(Q38131284)

29 August 2017

The cyclin-dependent kinase family in the social amoebozoan Dictyostelium discoideum (English)

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29 August 2017

Dictyostelium discoideum

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author name string

Robert J Huber

series ordinal

1

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PubMed ID

23974243

29 August 2017

language of work or name

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22 August 2013

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Cellular and Molecular Life Sciences

29 August 2017

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29 August 2017

71

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29 August 2017

4

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29 August 2017

629-639

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https://scigraph.springernature.com/pub.10.1007/s00018-013-1449-3

29 August 2017

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21 January 2018

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An overview of Cdk1-controlled targets and processes

21 January 2018

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Cell cycle, CDKs and cancer: a changing paradigm

21 January 2018

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Cyclin dependent kinases in cancer: potential for therapeutic intervention

21 January 2018

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Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution

21 January 2018

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The mammalian Mediator complex and its role in transcriptional regulation

21 January 2018

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Targeting of CDK8 to a promoter-proximal RNA element demonstrates catalysis-dependent activation of gene expression.

21 January 2018

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Mediator complexes and eukaryotic transcription regulation: an overview

21 January 2018

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Cyclin-dependent kinase 5 (cdk5) activation requires interaction with three domains of p35.

21 January 2018

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Extraneuronal roles of cyclin-dependent kinase 5.

21 January 2018

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Novel insights into the beneficial and detrimental actions of cdk5.

21 January 2018

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The impact of cyclin-dependent kinase 5 depletion on poly(ADP-ribose) polymerase activity and responses to radiation

21 January 2018

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Cdk5 targets active Src for ubiquitin-dependent degradation by phosphorylating Src(S75).

21 January 2018

1 reference

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Modulation of aberrant CDK5 signaling rescues impaired neurogenesis in models of Alzheimer's disease.

21 January 2018

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Cdk5: a multifaceted kinase in neurodegenerative diseases

21 January 2018

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Cdk5-mediated phosphorylation of endophilin B1 is required for induced autophagy in models of Parkinson's disease

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-013-1449-3

Simple system--substantial share: the use of Dictyostelium in cell biology and molecular medicine

21 January 2018

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Evolutionary crossroads in developmental biology: Dictyostelium discoideum

21 January 2018

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The cell cycle and its relationship to development in Dictyostelium discoideum

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1449-3

The developmental fate of Dictyostelium discoideum cells depends greatly on the cell-cycle position at the onset of starvation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1449-3

Cell-autonomous determination of cell-type choice in Dictyostelium development by cell-cycle phase

21 January 2018

1 reference

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Non-genetic heterogeneity and cell fate choice in Dictyostelium discoideum

21 January 2018

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Initial cell type choice in Dictyostelium

21 January 2018

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Prespore cell fate bias in G1 phase of the cell cycle in Dictyostelium discoideum

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1449-3

A retinoblastoma ortholog controls stalk/spore preference in Dictyostelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1449-3

Live imaging of the Dictyostelium cell cycle reveals widespread S phase during development, a G2 bias in spore differentiation and a premitotic checkpoint.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1449-3

Mitochondrial DNA replication but no nuclear DNA replication during development of Dictyostelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1449-3

Cyclin B and Cdc2 expression and Cd2 kinase activity during Dictyostelium differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1449-3

Isolation and characterization of a cdc 2 cDNA from Dictyostelium discoideum

21 January 2018

1 reference

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The ordering of expression among a few genes can provide simple cancer biomarkers and signal BRCA1 mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1449-3

Binding and catalytic properties of the Cdc2 and Crp proteins of Dictyostelium.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1449-3

The role of cyclin synthesis and degradation in the control of maturation promoting factor activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1449-3

Nucleocytoplasmic transfer of cyclin dependent kinase 5 and its binding to puromycin-sensitive aminopeptidase in Dictyostelium discoideum.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1449-3

The cyclin-dependent kinase inhibitor roscovitine inhibits kinase activity, cell proliferation, multicellular development, and Cdk5 nuclear translocation in Dictyostelium discoideum.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1449-3

The isolation from a unicellular organism, Dictyostelium discoideum, of a highly-related cdc2 gene with characteristics of the PCTAIRE subfamily.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1449-3

The cdk5/p35 kinase is essential for neurite outgrowth during neuronal differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1449-3

Differential roles of nuclear and cytoplasmic cyclin-dependent kinase 5 in apoptotic and excitotoxic neuronal death

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1449-3

Nuclear localization of Cdk5 is a key determinant in the postmitotic state of neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1449-3

Cdk5 and MAPK are associated with complexes of cytoskeletal proteins in rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1449-3

The neuronal p35 activator of Cdk5 is a novel F-actin binding and bundling protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1449-3

Dictyostelium puromycin-sensitive aminopeptidase A is a nucleoplasmic nucleomorphin-binding protein that relocates to the cytoplasm during mitosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1449-3

Bestatin inhibits cell growth, cell division, and spore cell differentiation in Dictyostelium discoideum

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1449-3

How the cyclin became a cyclin: regulated proteolysis in the cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1449-3

Puromycin-sensitive aminopeptidase. Sequence analysis, expression, and functional characterization

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1449-3

Cyclin-dependent kinase 5 is a calmodulin-binding protein that associates with puromycin-sensitive aminopeptidase in the nucleus of Dictyostelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1449-3

Calmodulin: a prototypical calcium sensor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1449-3

CaMBOT: profiling and characterizing calmodulin-binding proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1449-3

Scanning the human proteome for calmodulin-binding proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1449-3

Calmodulin binding and Cdk5 phosphorylation of p35 regulate its effect on microtubules

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1449-3

Calcium, calmodulin and cell cycle progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1449-3

Regulation of cell cycle progression by calcium/calmodulin-dependent pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1449-3

Inducible expression of calmodulin antisense RNA in Dictyostelium cells inhibits the completion of cytokinesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1449-3

Biochemical and cellular effects of roscovitine, a potent and selective inhibitor of the cyclin-dependent kinases cdc2, cdk2 and cdk5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1449-3

Roscovitine regulates invasive breast cancer cell (MDA-MB231) proliferation and survival through cell cycle regulatory protein cdk5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1449-3

Cyclin-dependent kinase 5 regulates endothelial cell migration and angiogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1449-3

Design, synthesis, and testing of an 6-O-linked series of benzimidazole based inhibitors of CDK5/p25.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1449-3

Roscovitine targets, protein kinases and pyridoxal kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1449-3

A uniform procedure for the purification of CDK7/CycH/MAT1, CDK8/CycC and CDK9/CycT1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1449-3

Roscovitine inhibits activation of promoters in herpes simplex virus type 1 genomes independently of promoter-specific factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1449-3

Potential use of pharmacological cyclin-dependent kinase inhibitors as anti-HIV therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1449-3

Roscovitine, a selective CDK inhibitor, reduces the basal and estrogen-induced phosphorylation of ER-α in human ER-positive breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1449-3

Cyclin-dependent kinase inhibitors enhance the resolution of inflammation by promoting inflammatory cell apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1449-3

Regulation of NMDA receptors by cyclin-dependent kinase-5

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1449-3

Cdk5 regulates the organization of Nestin and its association with p35

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1449-3

A novel Dictyostelium Cdk8 is required for aggregation, but is dispensable for growth.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1449-3

A homologue of Cdk8 is required for spore cell differentiation in Dictyostelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1449-3

Targets downstream of Cdk8 in Dictyostelium development

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1449-3

Control of cyclin C levels during development of Dictyostelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1449-3

Tissue-specific G1-phase cell-cycle arrest prior to terminal differentiation in Dictyostelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1449-3

Dependence of cell-type proportioning and sorting on cell cycle phase in Dictyostelium discoideum

21 January 2018

1 reference

12 December 2020

Dictyostelium as a model for human disease

1 reference

12 December 2020

The cdk5 homologue, crp, regulates endocytosis and secretion in dictyostelium and is necessary for optimum growth and differentiation

1 reference

12 December 2020

Overexpression of a truncated cyclin B gene arrests Dictyostelium cell division during mitosis.

1 reference

12 December 2020

Calmodulin and the contractile vacuole complex in mitotic cells of Dictyostelium discoideum

1 reference

12 December 2020

Intrathecal cdk5 inhibitor, roscovitine, attenuates morphine antinociceptive tolerance in rats

1 reference

12 December 2020

Aminopeptidases: structure and function

1 reference

12 December 2020

Analysis of cell cycle progression during the development of Dictyostelium and its relationship to differentiation

1 reference

12 December 2020

A revision of the Dictyostelium discoideum cell cycle

1 reference

12 December 2020

The cell cycle and sorting behaviour in Dictyostelium discoideum

1 reference

12 December 2020

p39 activates cdk5 in neurons, and is associated with the actin cytoskeleton

1 reference

12 December 2020

The effects of bestatin, a microbial aminopeptidase inhibitor, on epidermal growth factor-induced DNA synthesis and cell division in primary cultured hepatocytes of rats

1 reference

12 December 2020

The Dictyostelium cell cycle and its relationship to differentiation

1 reference

12 December 2020

Inhibition of Aminopeptidase and Acetylcholinesterase by Puromycin and Puromycin Analogs

1 reference

12 December 2020

dictyExpress: a Dictyostelium discoideum gene expression database with an explorative data analysis web-based interface.

1 reference

12 December 2020

10.1007/S00018-013-1449-3

Identifiers

DOI

1 reference

29 August 2017

1 reference

PubMed ID

23974243