(Q28576044)

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16192386%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

title

Differential roles of nuclear and cytoplasmic cyclin-dependent kinase 5 in apoptotic and excitotoxic neuronal death (English)

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16192386%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

0 references

1 reference

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16192386%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

Paul R. Albert

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16192386%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

David S Park

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16192386%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

5

Steven M Callaghan

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16192386%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

6

Ruth S Slack

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16192386%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

author name string

Neena Kushwaha

2

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16192386%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

Yi Zhang

3

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16192386%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

Inez Vincent

8

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16192386%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

Michael J O'Hare

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16192386%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

language of work or name

English

0 references

publication date

1 September 2005

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16192386%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

published in

Journal of Neuroscience

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16192386%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

volume

25

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16192386%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

issue

39

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16192386%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

page(s)

8954-8966

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16192386%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

7 January 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC6725602/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Cyclins and cell cycle checkpoints

1 reference

12 December 2020

Involvement of cell cycle elements, cyclin-dependent kinases, pRb, and E2F x DP, in B-amyloid-induced neuronal death

1 reference

12 December 2020

Bax-dependent caspase-3 activation is a key determinant in p53-induced apoptosis in neurons

1 reference

12 December 2020

Role of cell cycle regulatory proteins in cerebellar granule neuron apoptosis.

1 reference

12 December 2020

Inhibition of tau phosphorylating protein kinase cdk5 prevents beta-amyloid-induced neuronal death

1 reference

12 December 2020

Mitotic signaling by beta-amyloid causes neuronal death

1 reference

12 December 2020

Conversion of p35 to p25 deregulates Cdk5 activity and promotes neurodegeneration

1 reference

12 December 2020

Ran-mediated nuclear export of the von Hippel-Lindau tumor suppressor protein occurs independently of its assembly with cullin-2

1 reference

12 December 2020

Caspases cleave the amino-terminal calpain inhibitory unit of calpastatin during apoptosis in human Jurkat T cells

1 reference

12 December 2020

Calpain-dependent proteolytic cleavage of the p35 cyclin-dependent kinase 5 activator to p25

1 reference

12 December 2020

Involvement of retinoblastoma family members and E2F/DP complexes in the death of neurons evoked by DNA damage

1 reference

12 December 2020

Oxidative DNA damage precedes DNA fragmentation after experimental stroke in rat brain

1 reference

12 December 2020

Neurotoxicity induces cleavage of p35 to p25 by calpain

1 reference

12 December 2020

Involvement of caspase 3 in apoptotic death of cortical neurons evoked by DNA damage.

1 reference

12 December 2020

Induction and modulation of cerebellar granule neuron death by E2F-1

1 reference

12 December 2020

Regulation of G(1) cyclin-dependent kinases in the mammalian cell cycle

1 reference

12 December 2020

The levels of cdk5 and p35 proteins and tau phosphorylation are reduced during neuronal apoptosis

1 reference

12 December 2020

Mechanism of action of camptothecin

1 reference

12 December 2020

Ratio of 8-hydroxyguanine in intact DNA to free 8-hydroxyguanine is increased in Alzheimer disease ventricular cerebrospinal fluid

1 reference

12 December 2020

Deregulation of Cdk5 in a mouse model of ALS: toxicity alleviated by perikaryal neurofilament inclusions

1 reference

12 December 2020

Characterization and expression of calpain 10. A novel ubiquitous calpain with nuclear localization

1 reference

12 December 2020

Cyclin-dependent kinases and P53 pathways are activated independently and mediate Bax activation in neurons after DNA damage.

1 reference

12 December 2020

1 reference

12 December 2020

Early-onset ataxia with ocular motor apraxia and hypoalbuminemia is caused by mutations in a new HIT superfamily gene

1 reference

12 December 2020

The gene mutated in ataxia-ocular apraxia 1 encodes the new HIT/Zn-finger protein aprataxin

1 reference

12 December 2020

APAF1 is a key transcriptional target for p53 in the regulation of neuronal cell death.

1 reference

12 December 2020

Cyclin-dependent kinase 5 prevents neuronal apoptosis by negative regulation of c-Jun N-terminal kinase 3.

1 reference

12 December 2020

Cdc2 phosphorylation of BAD links the cell cycle to the cell death machinery

1 reference

12 December 2020

Interaction of the c-Jun/JNK pathway and cyclin-dependent kinases in death of embryonic cortical neurons evoked by DNA damage

1 reference

12 December 2020

Apoptosis-inducing factor is involved in the regulation of caspase-independent neuronal cell death

1 reference

12 December 2020

Mutation of TDP1, encoding a topoisomerase I-dependent DNA damage repair enzyme, in spinocerebellar ataxia with axonal neuropathy

1 reference

12 December 2020

Subcellular localization and in vivo subunit interactions of ubiquitous mu-calpain.

1 reference

12 December 2020

Cdk5-Mediated Inhibition of the Protective Effects of Transcription Factor MEF2 in Neurotoxicity-Induced Apoptosis

1 reference

12 December 2020

Calpains mediate p53 activation and neuronal death evoked by DNA damage.

1 reference

12 December 2020

Cyclin-dependent kinase-5 is involved in neuregulin-dependent activation of phosphatidylinositol 3-kinase and Akt activity mediating neuronal survival.

1 reference

12 December 2020

1 reference

12 December 2020

Cdk5 activation induces hippocampal CA1 cell death by directly phosphorylating NMDA receptors

1 reference

12 December 2020

Cyclin-dependent kinase 5 is a mediator of dopaminergic neuron loss in a mouse model of Parkinson's disease

1 reference

12 December 2020

Decreased cyclin-dependent kinase 5 (cdk5) activity is accompanied by redistribution of cdk5 and cytoskeletal proteins and increased cytoskeletal protein phosphorylation in p35 null mice.

1 reference

12 December 2020

Cdk5: mediator of neuronal death and survival

1 reference

12 December 2020

Gene regulation and DNA damage in the ageing human brain

1 reference

12 December 2020

The pathophysiology of mitochondrial cell death

1 reference

12 December 2020

p53 activation domain 1 is essential for PUMA upregulation and p53-mediated neuronal cell death

1 reference

12 December 2020

G1 cell-cycle control and cancer

1 reference

12 December 2020

Multiple agents rescue PC12 cells from serum-free cell death by translation- and transcription-independent mechanisms

1 reference

12 December 2020

A short amino acid sequence able to specify nuclear location

1 reference

12 December 2020

DNA damage and chronic neuronal degenerations

1 reference

12 December 2020

The HIV-1 Rev activation domain is a nuclear export signal that accesses an export pathway used by specific cellular RNAs

1 reference

12 December 2020

Bax-deficient mice with lymphoid hyperplasia and male germ cell death

1 reference

12 December 2020

An Isoform of the Neuronal Cyclin-dependent Kinase 5 (Cdk5) Activator

1 reference

12 December 2020

Selective nuclear transport of mu-calpain

1 reference

12 December 2020

m-Calpain requires DNA for activity on nuclear proteins at low calcium concentrations

1 reference

12 December 2020

DNA single-strand breaks in postischemic gerbil brain detected by in situ nick translation procedure

1 reference

12 December 2020

Induction of neuronal apoptosis by camptothecin, an inhibitor of DNA topoisomerase-I: evidence for cell cycle-independent toxicity

1 reference

12 December 2020

Evidence for p53-mediated modulation of neuronal viability.

1 reference

12 December 2020

Targeted disruption of the cyclin-dependent kinase 5 gene results in abnormal corticogenesis, neuronal pathology and perinatal death

1 reference

12 December 2020

Induction of CPP32-like activity in PC12 cells by withdrawal of trophic support. Dissociation from apoptosis

1 reference

12 December 2020

G1/S cell cycle blockers and inhibitors of cyclin-dependent kinases suppress camptothecin-induced neuronal apoptosis

1 reference

12 December 2020

Early detection of DNA strand breaks in the brain after transient focal ischemia: implications for the role of DNA damage in apoptosis and neuronal cell death.

1 reference

12 December 2020

Oxidative DNA damage in the parkinsonian brain: an apparent selective increase in 8-hydroxyguanine levels in substantia nigra.

1 reference

12 December 2020

Cyclin dependent kinase inhibitors and dominant negative cyclin dependent kinase 4 and 6 promote survival of NGF-deprived sympathetic neurons

1 reference

12 December 2020

Bax involvement in p53-mediated neuronal cell death

1 reference

12 December 2020

Oxidative mechanisms in nigral cell death in Parkinson's disease.

1 reference

12 December 2020

The regulation of E2F by pRB-family proteins

1 reference

12 December 2020

Caspase-mediated fragmentation of calpain inhibitor protein calpastatin during apoptosis

1 reference

12 December 2020

p35, the neuronal-specific activator of cyclin-dependent kinase 5 (Cdk5) is degraded by the ubiquitin-proteasome pathway.

1 reference

12 December 2020

Apaf1 (CED-4 homolog) regulates programmed cell death in mammalian development

1 reference

12 December 2020

Cyclin-dependent kinases participate in death of neurons evoked by DNA-damaging agents

1 reference

12 December 2020

Increased nuclear DNA oxidation in the brain in Alzheimer's disease.

1 reference

12 December 2020

Transcription-dependent nuclear-cytoplasmic trafficking is required for the function of the von Hippel-Lindau tumor suppressor protein

1 reference

12 December 2020

Cleavage of the calpain inhibitor, calpastatin, during apoptosis

1 reference

12 December 2020

10.1523/JNEUROSCI.2899-05.2005

Identifiers

DOI

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16192386%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16192386%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

2 references

31 January 2017