(Q38134108)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24003925%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

title

The targeting of β-cells by T lymphocytes in human type 1 diabetes: clinical perspectives (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24003925%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

0 references

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24003925%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

Christian Boitard

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24003925%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

author name string

C Briet

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24003925%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

C Bécourt

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24003925%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

F Lemonnier

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24003925%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

language of work or name

1 reference

1 September 2013

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24003925%20AND%20SRC:MED&resulttype=core&format=json

Diabetes, Obesity and Metabolism

19 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24003925%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

volume

15 Suppl 3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24003925%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

page(s)

89-97

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24003925%20AND%20SRC:MED&resulttype=core&format=json

HLA class I and genetic susceptibility to type 1 diabetes: results from the Type 1 Diabetes Genetics Consortium

19 February 2020

cites work

1 reference

Genetics of type 1A diabetes

21 January 2018

1 reference

Role of beta-cells in type 1 diabetes pathogenesis

21 January 2018

1 reference

Modifier loci condition autoimmunity provoked by Aire deficiency

21 January 2018

1 reference

Prediction and pathogenesis in type 1 diabetes.

21 January 2018

1 reference

T cell recognition of autoantigens in human type 1 diabetes: clinical perspectives

21 January 2018

1 reference

Beyond the hormone: insulin as an autoimmune target in type 1 diabetes

21 January 2018

1 reference

Acceleration of type 1 diabetes mellitus in proinsulin 2-deficient NOD mice

21 January 2018

1 reference

T cell epitopes of insulin defined in HLA-DR4 transgenic mice are derived from preproinsulin and proinsulin

21 January 2018

1 reference

Pro- and anti-inflammatory cytokine production by autoimmune T cells against preproinsulin in HLA-DRB1*04, DQ8 Type 1 diabetes

21 January 2018

1 reference

A disease-associated cellular immune response in type 1 diabetics to an immunodominant epitope of insulin

21 January 2018

1 reference

Structure of a human insulin peptide-HLA-DQ8 complex and susceptibility to type 1 diabetes

21 January 2018

1 reference

Autoreactive T cell responses show proinflammatory polarization in diabetes but a regulatory phenotype in health

21 January 2018

1 reference

The insulin A-chain epitope recognized by human T cells is posttranslationally modified

21 January 2018

1 reference

Recognition of a subregion of human proinsulin by class I-restricted T cells in type 1 diabetic patients

21 January 2018

1 reference

Recognition of human proinsulin leader sequence by class I-restricted T-cells in HLA-A*0201 transgenic mice and in human type 1 diabetes

21 January 2018

1 reference

Autoreactive CD8 T cells associated with beta cell destruction in type 1 diabetes

21 January 2018

1 reference

Human β-cell killing by autoreactive preproinsulin-specific CD8 T cells is predominantly granule-mediated with the potency dependent upon T-cell receptor avidity

21 January 2018

1 reference

Single insulin-specific CD8+ T cells show characteristic gene expression profiles in human type 1 diabetes

21 January 2018

1 reference

Naturally processed T cell epitopes from human glutamic acid decarboxylase identified using mice transgenic for the type 1 diabetes-associated human MHC class II allele, DRB1*0401.

21 January 2018

1 reference

Identification and modulation of a naturally processed T cell epitope from the diabetes-associated autoantigen human glutamic acid decarboxylase 65 (hGAD65).

21 January 2018

1 reference

Induction of insulitis by glutamic acid decarboxylase peptide-specific and HLA-DQ8-restricted CD4(+) T cells from human DQ transgenic mice

21 January 2018

1 reference

Autoreactive human T-cell receptor initiates insulitis and impaired glucose tolerance in HLA DR4 transgenic mice

21 January 2018

1 reference

Detection of GAD65-specific T-cells by major histocompatibility complex class II tetramers in type 1 diabetic patients and at-risk subjects

21 January 2018

1 reference

Identification of naturally processed T cell epitopes from glutamic acid decarboxylase presented in the context of HLA-DR alleles by T lymphocytes of recent onset IDDM patients

21 January 2018

1 reference

Recurrence of type 1 diabetes after simultaneous pancreas-kidney transplantation, despite immunosuppression, is associated with autoantibodies and pathogenic autoreactive CD4 T-cells.

21 January 2018

1 reference

Cellular immunity to a determinant common to glutamate decarboxylase and coxsackie virus in insulin-dependent diabetes

21 January 2018

1 reference

GAD65-reactive T cells are activated in patients with autoimmune type 1a diabetes

21 January 2018

1 reference

HLA-DQ8-associated T cell responses to the diabetes autoantigen phogrin (IA-2 beta) in human prediabetes

21 January 2018

1 reference

Islet-specific glucose-6-phosphatase catalytic subunit-related protein-reactive CD4+ T cells in human subjects.

21 January 2018

1 reference

Evidence for molecular mimicry between human T cell epitopes in rotavirus and pancreatic islet autoantigens

21 January 2018

1 reference

Autoantibodies and associated T-cell responses to determinants within the 831-860 region of the autoantigen IA-2 in Type 1 diabetes.

21 January 2018

1 reference

Cytotoxic T cells specific for glutamic acid decarboxylase in autoimmune diabetes

21 January 2018

1 reference

Identification of Novel HLA-A*0201-restricted epitopes in recent-onset type 1 diabetic subjects and antibody-positive relatives

21 January 2018

1 reference

Recognition of HLA class I-restricted beta-cell epitopes in type 1 diabetes.

21 January 2018

1 reference

HLA-B7-restricted islet epitopes are differentially recognized in type 1 diabetic children and adults and form weak peptide-HLA complexes

21 January 2018

1 reference

Simultaneous detection of circulating autoreactive CD8+ T-cells specific for different islet cell-associated epitopes using combinatorial MHC multimers.

21 January 2018

1 reference

Naturally arising human CD4 T-cells that recognize islet autoantigens and secrete interleukin-10 regulate proinflammatory T-cell responses via linked suppression

21 January 2018

1 reference

Functional avidity directs T-cell fate in autoreactive CD4+ T cells

21 January 2018

1 reference

Class III alleles at the insulin VNTR polymorphism are associated with regulatory T-cell responses to proinsulin epitopes in HLA-DR4, DQ8 individuals

21 January 2018

1 reference

DRB1*0401-restricted human T cell clone specific for the major proinsulin73-90 epitope expresses a down-regulatory T helper 2 phenotype

21 January 2018

1 reference

Comparative study of GAD65-specific CD4+ T cells in healthy and type 1 diabetic subjects

21 January 2018

1 reference

Defects in IL-2R signaling contribute to diminished maintenance of FOXP3 expression in CD4(+)CD25(+) regulatory T-cells of type 1 diabetic subjects

21 January 2018

1 reference

CD8+ suppressor-mediated regulation of human CD4+ T cell responses to glutamic acid decarboxylase 65.

21 January 2018

1 reference

Humanized mice for immune system investigation: progress, promise and challenges

21 January 2018

1 reference

Phenotypic alterations in insulin-deficient mutant mice.

21 January 2018

1 reference

HLA-A2.1-restricted education and cytolytic activity of CD8(+) T lymphocytes from beta2 microglobulin (beta2m) HLA-A2.1 monochain transgenic H-2Db beta2m double knockout mice

21 January 2018

1 reference

Effect of cyclosporin A treatment on the production of antibody in insulin-dependent (type I) diabetic patients

21 January 2018

1 reference

GAD65- and proinsulin-specific CD4+ T-cells detected by MHC class II tetramers in peripheral blood of type 1 diabetes patients and at-risk subjects

21 January 2018

1 reference

Identification of a -Cell-Specific HLA Class I Restricted Epitope in Type 1 Diabetes

21 January 2018

1 reference