(Q38186800)

30 August 2017

title

Uncovering the pathogenesis of large granular lymphocytic leukemia-novel STAT3 and STAT5b mutations (English)

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30 August 2017

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Kimmo Porkka

2

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Satu Mustjoki

object named as

Satu Mustjoki

5

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author name string

Hanna L M Rajala

1

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30 August 2017

Jaroslaw P Maciejewski

3

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30 August 2017

Thomas P Loughran

4

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30 August 2017

language of work or name

English

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publication date

11 February 2014

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30 August 2017

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30 August 2017

volume

46

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30 August 2017

issue

3

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30 August 2017

page(s)

114-122

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Leukemia of large granular lymphocytes: association with clonal chromosomal abnormalities and autoimmune neutropenia, thrombocytopenia, and hemolytic anemia

30 August 2017

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21 January 2018

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21 January 2018

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Constitutive activation of Stat3 by the Src and JAK tyrosine kinases participates in growth regulation of human breast carcinoma cells

21 January 2018

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STAT3 is constitutively activated in Hodgkin cell lines

21 January 2018

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Exome sequencing of head and neck squamous cell carcinoma reveals inactivating mutations in NOTCH1

21 January 2018

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Initial genome sequencing and analysis of multiple myeloma

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Cytokines in arthritis--the 'big numbers' move centre stage

21 January 2018

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Pathophysiology of psoriasis: recent advances on IL-23 and Th17 cytokines

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Human TH17 lymphocytes promote blood-brain barrier disruption and central nervous system inflammation

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STAT3 mutations are highly specific for large granular lymphocytic leukemia

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Somatic mutations activating STAT3 in human inflammatory hepatocellular adenomas

21 January 2018

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STAT3 mutations identified in human hematologic neoplasms induce myeloid malignancies in a mouse bone marrow transplantation model.

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Frequent in-frame somatic deletions activate gp130 in inflammatory hepatocellular tumours

21 January 2018

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A novel missense (M206K) STAT3 mutation in diffuse large B cell lymphoma deregulates STAT3 signaling

21 January 2018

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STAT3 exon 21 mutation is rare in common human cancers

21 January 2018

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STAT3 mutations indicate the presence of subclinical T-cell clones in a subset of aplastic anemia and myelodysplastic syndrome patients

21 January 2018

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Requirement of STAT5b for sexual dimorphism of body growth rates and liver gene expression

21 January 2018

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Stat5b is essential for natural killer cell-mediated proliferation and cytolytic activity

21 January 2018

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A novel Ncr1-Cre mouse reveals the essential role of STAT5 for NK-cell survival and development

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Human papillomavirus is a necessary cause of invasive cervical cancer worldwide

21 January 2018

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21 January 2018

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STAT3 transcription factor is constitutively activated and is oncogenic in nasal-type NK/T-cell lymphoma

21 January 2018

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https://api.crossref.org/works/10.3109%2F07853890.2014.882105

Aberrant expression and constitutive activation of STAT3 in cervical carcinogenesis: implications in high-risk human papillomavirus infection

21 January 2018

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21 January 2018

LGL leukemia and HTLV.

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Molecular analysis of TCR clonotypes in LGL: a clonal model for polyclonal responses.

21 January 2018

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Aberrant overexpression of IL-15 initiates large granular lymphocyte leukemia through chromosomal instability and DNA hypermethylation

21 January 2018

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Systematic characterization of human CD8+ T cells with natural killer cell markers in comparison with natural killer cells and normal CD8+ T cells

21 January 2018

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21 January 2018

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Mono/oligoclonal T and NK cells are common in chronic myeloid leukemia patients at diagnosis and expand during dasatinib therapy.

21 January 2018

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Functional heterogeneity and high frequencies of cytomegalovirus-specific CD8(+) T lymphocytes in healthy seropositive donors.

21 January 2018

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https://api.crossref.org/works/10.3109%2F07853890.2014.882105

Clonal expansion of T/NK-cells during tyrosine kinase inhibitor dasatinib therapy

21 January 2018

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https://api.crossref.org/works/10.3109%2F07853890.2014.882105

Clonal populations of T cells in normal elderly humans: the T cell equivalent to "benign monoclonal gammapathy".

21 January 2018

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https://api.crossref.org/works/10.3109%2F07853890.2014.882105

Orally bioavailable small-molecule inhibitor of transcription factor Stat3 regresses human breast and lung cancer xenografts

21 January 2018

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https://api.crossref.org/works/10.3109%2F07853890.2014.882105

A STAT3-decoy oligonucleotide induces cell death in a human colorectal carcinoma cell line by blocking nuclear transfer of STAT3 and STAT3-bound NF-κB.

21 January 2018

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https://api.crossref.org/works/10.3109%2F07853890.2014.882105

Small molecule STAT5-SH2 domain inhibitors exhibit potent antileukemia activity

21 January 2018

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Therapeutic modulators of STAT signalling for human diseases

21 January 2018

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https://api.crossref.org/works/10.3109%2F07853890.2014.882105

The STAT5 Inhibitor Pimozide Displays Efficacy in Models of Acute Myelogenous Leukemia Driven by FLT3 Mutations

21 January 2018

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https://api.crossref.org/works/10.3109%2F07853890.2014.882105

Myelodysplastic Syndromes

21 January 2018

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10.3109/07853890.2014.882105

21 January 2018

Identifiers

DOI

1 reference

30 August 2017

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