(Q38187337)

30 August 2017

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Caspases and inflammasomes in metabolic inflammation (English)

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30 August 2017

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Alexander M Skeldon

1

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30 August 2017

May Faraj

series ordinal

2

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30 August 2017

Maya Saleh

series ordinal

3

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30 August 2017

publication date

11 February 2014

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Immunology & Cell Biology

30 August 2017

published in

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30 August 2017

volume

92

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30 August 2017

issue

4

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30 August 2017

page(s)

304-313

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Immunological and inflammatory functions of the interleukin-1 family

30 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.5

Inflammatory links between obesity and metabolic disease

21 January 2018

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Adipose tissue inflammation and ectopic lipid accumulation

21 January 2018

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Visceral and subcutaneous adipose tissue volumes are cross-sectionally related to markers of inflammation and oxidative stress: the Framingham Heart Study

21 January 2018

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Adipocyte dysfunctions linking obesity to insulin resistance and type 2 diabetes

21 January 2018

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Inflammation and metabolic disorders

21 January 2018

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Chronic exposure to interleukin-6 causes hepatic insulin resistance in mice

21 January 2018

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https://api.crossref.org/works/10.1038%2FICB.2014.5

Diabetes, lipids, and adipocyte secretagogues

21 January 2018

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Effects of acute hyperinsulinemia on VLDL triglyceride and VLDL apoB production in normal weight and obese individuals

21 January 2018

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Type 2 diabetes: principles of pathogenesis and therapy

21 January 2018

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Regulation of plasma triglycerides in insulin resistance and diabetes

21 January 2018

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https://api.crossref.org/works/10.1038%2FICB.2014.5

The machinery of Nod-like receptors: refining the paths to immunity and cell death

21 January 2018

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https://api.crossref.org/works/10.1038%2FICB.2014.5

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.5

Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.5

Linking lipid metabolism to the innate immune response in macrophages through sterol regulatory element binding protein-1a.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.5

Non-canonical inflammasome activation targets caspase-11

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.5

The inflammasome-mediated caspase-1 activation controls adipocyte differentiation and insulin sensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.5

Inflammasome is a central player in the induction of obesity and insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.5

Obesity development in caspase-1-deficient mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.5

Role of caspase-1 in regulation of triglyceride metabolism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.5

Fatty acid-induced NLRP3-ASC inflammasome activation interferes with insulin signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.5

The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.5

Functional interactions between the gut microbiota and host metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.5

An obesity-associated gut microbiome with increased capacity for energy harvest

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.5

NLRP6 inflammasome regulates colonic microbial ecology and risk for colitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.5

Familial transmission rather than defective innate immunity shapes the distinct intestinal microbiota of TLR-deficient mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.5

Metabolic syndrome and altered gut microbiota in mice lacking Toll-like receptor 5

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.5

Caspase-1 deficiency in mice reduces intestinal triglyceride absorption and hepatic triglyceride secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.5

The caspase-1 digestome identifies the glycolysis pathway as a target during infection and septic shock

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.5

PPARγ signaling and metabolism: the good, the bad and the future

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.5

Caspase-mediated degradation of PPARgamma proteins in adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.5

Tumor necrosis factor-alpha induces caspase-mediated cleavage of peroxisome proliferator-activated receptor gamma in adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.5

Sirtuins mediate mammalian metabolic responses to nutrient availability

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.5

High-fat diet triggers inflammation-induced cleavage of SIRT1 in adipose tissue to promote metabolic dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.5

Serine phosphorylation of insulin receptor substrate 1 by inhibitor kappa B kinase complex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.5

A central role for JNK in obesity and insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.5

The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.5

The cellular and signaling networks linking the immune system and metabolism in disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.5

Thioredoxin-interacting protein links oxidative stress to inflammasome activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.5

Elimination of the NLRP3-ASC inflammasome protects against chronic obesity-induced pancreatic damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.5

Activation of the Nlrp3 inflammasome in infiltrating macrophages by endocannabinoids mediates beta cell loss in type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.5

Purification and characterization of a peptide from amyloid-rich pancreases of type 2 diabetic patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.5

Diabetes due to a progressive defect in beta-cell mass in rats transgenic for human islet amyloid polypeptide (HIP Rat): a new model for type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.5

Spontaneous diabetes mellitus in transgenic mice expressing human islet amyloid polypeptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.5

Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.5

IRE1α induces thioredoxin-interacting protein to activate the NLRP3 inflammasome and promote programmed cell death under irremediable ER stress.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.5

Thioredoxin-interacting protein mediates ER stress-induced β cell death through initiation of the inflammasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.5

Atherosclerosis: current pathogenesis and therapeutic options

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.5

Macrophages in atherosclerosis: a dynamic balance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.5

NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.5

Cholesterol crystals activate the NLRP3 inflammasome in human macrophages: a novel link between cholesterol metabolism and inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.5

Scavenger receptors class A-I/II and CD36 are the principal receptors responsible for the uptake of modified low density lipoprotein leading to lipid loading in macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.5

CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.5

CD36 coordinates NLRP3 inflammasome activation by facilitating intracellular nucleation of soluble ligands into particulate ligands in sterile inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.5

Spontaneous hypercholesterolemia and arterial lesions in mice lacking apolipoprotein E

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.5

Atherosclerosis in ApoE-deficient mice progresses independently of the NLRP3 inflammasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.5

Interaction between free fatty acids and glucose metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.5

TLR4 links innate immunity and fatty acid-induced insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.5

Fetuin-A acts as an endogenous ligand of TLR4 to promote lipid-induced insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.5

A ceramide-centric view of insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.5

Hyperglycemia activates caspase-1 and TXNIP-mediated IL-1beta transcription in human adipose tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.5

Cryopyrin activates the inflammasome in response to toxins and ATP

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.5

The ATP-P2X7 signaling axis is dispensable for obesity-associated inflammasome activation in adipose tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.5

Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.5

Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.5

Gout-associated uric acid crystals activate the NALP3 inflammasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.5

Interleukin-1beta-induced insulin resistance in adipocytes through down-regulation of insulin receptor substrate-1 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.5

Lack of interleukin-1 receptor I (IL-1RI) protects mice from high-fat diet-induced adipose tissue inflammation coincident with improved glucose homeostasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.5

IL-1 plays an important role in lipid metabolism by regulating insulin levels under physiological conditions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.5

Interleukin-18 controls energy homeostasis by suppressing appetite and feed efficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.5

Interleukin-18 activates skeletal muscle AMPK and reduces weight gain and insulin resistance in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.5

Elevated plasma interleukin-18 is a marker of insulin-resistance in type 2 diabetic and non-diabetic humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.5

Elevated interleukin-18 levels are associated with the metabolic syndrome independent of obesity and insulin resistance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.5

Metabolic checkpoints in activated T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.5

Orchestration of metabolism by macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.5

Succinate is an inflammatory signal that induces IL-1β through HIF-1α.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.5

Sterol regulatory element binding protein 2 activation of NLRP3 inflammasome in endothelium mediates hemodynamic-induced atherosclerosis susceptibility.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.5

Caspase-1 activation of lipid metabolic pathways in response to bacterial pore-forming toxins promotes cell survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.5

Upregulated NLRP3 inflammasome activation in patients with type 2 diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.5

Expression of NLRP3 inflammasome and T cell population markers in adipose tissue are associated with insulin resistance and impaired glucose metabolism in humans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.5

Obesity phenotype is related to NLRP3 inflammasome activity and immunological profile of visceral adipose tissue.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.5

Interleukin-1-receptor antagonist in type 2 diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.5

Sustained effects of interleukin-1 receptor antagonist treatment in type 2 diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.5

Effects of gevokizumab on glycemia and inflammatory markers in type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.5

Resolvins: anti-inflammatory and proresolving mediators derived from omega-3 polyunsaturated fatty acids.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.5

Omega-3 fatty acids prevent inflammation and metabolic disorder through inhibition of NLRP3 inflammasome activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.5

Glyburide inhibits the Cryopyrin/Nalp3 inflammasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.5

Critical role of caspase-1 in vascular inflammation and development of atherosclerosis in Western diet-fed apolipoprotein E-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.5

Defective regulation of triglyceride metabolism by insulin in the liver in NIDDM

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.5

7 January 2021

Cytotoxicity of human pI 7 interleukin-1 for pancreatic islets of Langerhans

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.5

7 January 2021

Decreased fat mass in interleukin-1 receptor antagonist-deficient mice: impact on adipogenesis, food intake, and energy expenditure

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.5

7 January 2021

Deficiency of interleukin-18 in mice leads to hyperphagia, obesity and insulin resistance

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.5

7 January 2021

Elevated levels of interleukin-18 and tumor necrosis factor-alpha in serum of patients with type 2 diabetes mellitus: relationship with diabetic nephropathy

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.5

7 January 2021

Identifiers

DOI

10.1038/ICB.2014.5

1 reference

release_psj5k4vvdzdnvjzbuk3ak7cz7q

30 August 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/psj5k4vvdzdnvjzbuk3ak7cz7q

24 November 2022

mapped directly with Wikidata item

1 reference