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English
The pathophysiology and pharmacology of hepcidin.
scientific article published on 17 February 2014
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instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PMC publication ID
3978192
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24552640%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 March 2020
title
The pathophysiology and pharmacology of hepcidin
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
3978192
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24552640%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 March 2020
main subject
pharmacology
1 reference
based on heuristic
inferred from title
pathophysiology
1 reference
based on heuristic
inferred from title
author
Piotr Ruchala
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
3978192
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24552640%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 March 2020
author name string
Elizabeta Nemeth
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
3978192
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24552640%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 March 2020
publication date
17 February 2014
1 reference
stated in
Europe PubMed Central
PMC publication ID
3978192
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24552640%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 March 2020
published in
Trends in Pharmacological Sciences
1 reference
stated in
Europe PubMed Central
PMC publication ID
3978192
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24552640%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 March 2020
volume
35
1 reference
stated in
Europe PubMed Central
PMC publication ID
3978192
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24552640%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 March 2020
issue
3
1 reference
stated in
Europe PubMed Central
PMC publication ID
3978192
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24552640%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 March 2020
page(s)
155-161
1 reference
stated in
Europe PubMed Central
PMC publication ID
3978192
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24552640%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 March 2020
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A hepcidin lowering agent mobilizes iron for incorporation into red blood cells in an adenine-induced kidney disease model of anemia in rats.
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High-throughput screening of small molecules identifies hepcidin antagonists
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An RNAi therapeutic targeting Tmprss6 decreases iron overload in Hfe(-/-) mice and ameliorates anemia and iron overload in murine β-thalassemia intermedia
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The hemochromatosis proteins HFE, TfR2, and HJV form a membrane-associated protein complex for hepcidin regulation
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Hepcidin-induced endocytosis of ferroportin is dependent on ferroportin ubiquitination
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Minihepcidins are rationally designed small peptides that mimic hepcidin activity in mice and may be useful for the treatment of iron overload
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Perturbation of hepcidin expression by BMP type I receptor deletion induces iron overload in mice
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Neogenin inhibits HJV secretion and regulates BMP-induced hepcidin expression and iron homeostasis
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The serine protease matriptase-2 (TMPRSS6) inhibits hepcidin activation by cleaving membrane hemojuvelin
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Iron regulates phosphorylation of Smad1/5/8 and gene expression of Bmp6, Smad7, Id1, and Atoh8 in the mouse liver
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Mutations in TMPRSS6 cause iron-refractory iron deficiency anemia (IRIDA)
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Dorsomorphin inhibits BMP signals required for embryogenesis and iron metabolism
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Targets of anticytokine therapy and the risk of infections in humans and mice
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6 September 2017
Posttranslational processing of hepcidin in human hepatocytes is mediated by the prohormone convertase furin
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6 September 2017
Modulation of bone morphogenetic protein signaling in vivo regulates systemic iron balance
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6 September 2017
Transferrin receptor 2: evidence for ligand-induced stabilization and redirection to a recycling pathway
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6 September 2017
Hereditary hemochromatosis protein, HFE, interaction with transferrin receptor 2 suggests a molecular mechanism for mammalian iron sensing
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6 September 2017
Suppression of hepcidin during anemia requires erythropoietic activity
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6 September 2017
Regulation of iron metabolism by hepcidin
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PubMed Central
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6 September 2017
A role of SMAD4 in iron metabolism through the positive regulation of hepcidin expression
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6 September 2017
The iron exporter ferroportin/Slc40a1 is essential for iron homeostasis
1 reference
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6 September 2017
Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization
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PubMed Central
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6 September 2017
Mutations in HFE2 cause iron overload in chromosome 1q-linked juvenile hemochromatosis
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6 September 2017
The gene encoding the iron regulatory peptide hepcidin is regulated by anemia, hypoxia, and inflammation
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6 September 2017
Liver iron concentrations and urinary hepcidin in beta-thalassemia
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14 September 2017
Serum and liver iron differently regulate the bone morphogenetic protein 6 (BMP6)-SMAD signaling pathway in mice
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28 September 2017
Hepcidin-25 concentrations are markedly increased in patients with chronic kidney disease and are inversely correlated with estimated glomerular filtration rates.
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PubMed Central
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31 August 2018
A fully human anti-hepcidin antibody modulates iron metabolism in both mice and nonhuman primates
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31 August 2018
Testosterone perturbs systemic iron balance through activation of epidermal growth factor receptor signaling in the liver and repression of hepcidin
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31 August 2018
Transfusion suppresses erythropoiesis and increases hepcidin in adult patients with β-thalassemia major: a longitudinal study
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PubMed Central
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31 August 2018
Effects of subcutaneous and intravenous golimumab on inflammatory biomarkers in patients with rheumatoid arthritis: results of a phase 1, randomized, open-label trial
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31 August 2018
Heparin: a potent inhibitor of hepcidin expression in vitro and in vivo
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31 August 2018
Autosomal dominant hereditary hemochromatosis associated with a novel ferroportin mutation and unique clinical features
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31 August 2018
Hepcidin is decreased in TFR2 hemochromatosis
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978192
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31 August 2018
Blunted hepcidin response to oral iron challenge in HFE-related hemochromatosis
1 reference
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PubMed Central
reference URL
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1 October 2018
Estrogen regulates iron homeostasis through governing hepatic hepcidin expression via an estrogen response element
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24552640
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Constitutive hepcidin expression prevents iron overload in a mouse model of hemochromatosis
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24552640
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Hepcidin regulation by innate immune and infectious stimuli
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24552640
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1016/J.TIPS.2014.01.004
1 reference
stated in
Europe PubMed Central
PMC publication ID
3978192
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24552640%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 March 2020
PMC publication ID
3978192
1 reference
stated in
Europe PubMed Central
PMC publication ID
3978192
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24552640%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 March 2020
PubMed publication ID
24552640
1 reference
stated in
Europe PubMed Central
PMC publication ID
3978192
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24552640%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 March 2020
ResearchGate publication ID
260269994
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