(Q38189661)

30 August 2017

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title

Delivery of pineal melatonin to the brain and SCN: role of canaliculi, cerebrospinal fluid, tanycytes and Virchow-Robin perivascular spaces (English)

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30 August 2017

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1

Russel J Reiter

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30 August 2017

2

Dun Xian Tan

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30 August 2017

Seok Joong Kim

3

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30 August 2017

Maria Helena C Cruz

series ordinal

4

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30 August 2017

publication date

20 February 2014

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Brain Structure and Function

30 August 2017

published in

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30 August 2017

volume

219

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30 August 2017

issue

6

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30 August 2017

page(s)

1873-1887

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Melatonin-mitochondria interplay in health and disease.

30 August 2017

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21 January 2018

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21 January 2018

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High concentrations of the melatonin metabolite, N1-acetyl-N2-formyl-5-methoxykynuramine, in cerebrospinal fluid of patients with meningitis: a possible immunomodulatory mechanism.

21 January 2018

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Spontaneous central melatonin secretion and resorption kinetics of exogenous melatonin: a ventricular CSF study

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Melatonin as a natural ally against oxidative stress: a physicochemical examination.

21 January 2018

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On the free radical scavenging activities of melatonin's metabolites, AFMK and AMK.

21 January 2018

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Circadian actions of melatonin at the suprachiasmatic nucleus

21 January 2018

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Effects of melatonin treatment in septic newborns.

21 January 2018

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Melatonin, the circadian multioscillator system and health: the need for detailed analyses of peripheral melatonin signaling.

21 January 2018

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Melatonin: daily cycle in plasma and cerebrospinal fluid of calves

21 January 2018

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The Epiphyseal Complex in Fish and Reptiles

21 January 2018

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Melatonin plus exercise-based neurorehabilitative therapy for spinal cord injury

21 January 2018

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Genetic deletion of MT(1) and MT(2) melatonin receptors differentially abrogates the development and expression of methamphetamine-induced locomotor sensitization during the day and the night in C3H/HeN mice

21 January 2018

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Nose-to-brain transport of melatonin from polymer gel suspensions: a microdialysis study in rats

21 January 2018

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Presence of a distinct 24-hour melatonin rhythm in the ventricular cerebrospinal fluid of the goat

21 January 2018

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21 January 2018

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Circadian molecular clocks and cancer

21 January 2018

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Evidence that membrane-bound G protein-coupled melatonin receptors MT1 and MT2 are not involved in the neuroprotective effects of melatonin in focal cerebral ischemia.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00429-014-0719-7

Effects of memantine and melatonin on signal transduction pathways vascular leakage and brain injury after focal cerebral ischemia in mice

21 January 2018

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Mitochondrial fragmentation in neurodegeneration

21 January 2018

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21 January 2018

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Melatonin attenuates decrease of protein phosphatase 2A subunit B in ischemic brain injury

21 January 2018

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Scanning electron microscope observations of the canaliculi in the rat pineal gland

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Recirculation of cerebrospinal fluid through the tela choroidae is why high levels of melatonin can be found in the lateral ventricles

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00429-014-0719-7

Choroid plexus portals and a deficiency of melatonin can explain the neuropathology of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00429-014-0719-7

Melatonin synergizes with low doses of L-DOPA to improve dendritic spine density in the mouse striatum in experimental Parkinsonism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00429-014-0719-7

Sleep disorders in the older adult - a mini-review

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00429-014-0719-7

Rhythms of glutathione peroxidase and glutathione reductase in brain of chick and their inhibition by light

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00429-014-0719-7

Beneficial effects of endogenous and exogenous melatonin on neural reconstruction and functional recovery in an animal model of spinal cord injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00429-014-0719-7

Phase advance with separate and combined melatonin and light treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00429-014-0719-7

A serum melatonin rhythm in chickens and its abolition by pinealectomy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00429-014-0719-7

Melatonin: from seasonal to circadian signal

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00429-014-0719-7

Melatonin: both master clock output and internal time-giver in the circadian clocks network

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00429-014-0719-7

Daily rhythm of glucose-induced insulin secretion by isolated islets from intact and pinealectomized rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00429-014-0719-7

Melatonin, hydroxyl radical-mediated oxidative damage, and aging: a hypothesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00429-014-0719-7

Retrograde perfusions of the pineal region and the question of pineal vascular routes to brain and choroid plexuses

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00429-014-0719-7

Pineal canaliculi: demonstration, twenty-four-hour rhythmicity and experimental modification

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00429-014-0719-7

Endocrine Aspects of the Mammalian Pineal Gland:A Review

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00429-014-0719-7

What constitutes a physiological concentration of melatonin?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00429-014-0719-7

Melatonin as a pharmacological agent against neuronal loss in experimental models of Huntington's disease, Alzheimer's disease and parkinsonism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00429-014-0719-7

Free Radical-Mediated Molecular Damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00429-014-0719-7

Evidence for a 'paravascular' fluid circulation in the mammalian central nervous system, provided by the rapid distribution of tracer protein throughout the brain from the subarachnoid space

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00429-014-0719-7

The effects of environmental lighting on the daily melatonin rhythm in primate cerebrospinal fluid.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00429-014-0719-7

Oxidation and ubiquitination in neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00429-014-0719-7

Regulation of antioxidant enzymes: a significant role for melatonin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00429-014-0719-7

Hypothalamic tanycytes: a key component of brain-endocrine interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00429-014-0719-7

Occurrence, diel patterns, and the influence of melatonin on the photosynthetic performance of cultured Symbiodinium

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00429-014-0719-7

Alzheimer's disease: pathological mechanisms and the beneficial role of melatonin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00429-014-0719-7

The spectral composition of evening light and individual differences in the suppression of melatonin and delay of sleep in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00429-014-0719-7

The central circadian timing system

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00429-014-0719-7

How to fix a broken clock

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00429-014-0719-7

Electrophysiological Effects of Melatonin on Mouse Per1 and non‐Per1 Suprachiasmatic Nuclei Neurones In Vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00429-014-0719-7

Endogenous melatonin increases in cerebrospinal fluid of patients after severe traumatic brain injury and correlates with oxidative stress and metabolic disarray.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00429-014-0719-7

Observations on the pineal system in the hamster. I. Relations of the superficial and deep pineal to the epithalamus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00429-014-0719-7

An interesting anatomical relationship between the hamster pineal gland and the ventricular system of the brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00429-014-0719-7

Chemical and physical properties and potential mechanisms: melatonin as a broad spectrum antioxidant and free radical scavenger.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00429-014-0719-7

Evolving concepts about the role of acidosis in ischemic neuropathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00429-014-0719-7

Melatonin enters the cerebrospinal fluid through the pineal recess

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00429-014-0719-7

Cellular lining of the sheep pineal recess studied by light-, transmission-, and scanning electron microscopy: morphologic indications for a direct secretion of melatonin from the pineal gland to the cerebrospinal fluid

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00429-014-0719-7

The Virchow-Robin spaces: delineation by magnetic resonance imaging with considerations on anatomofunctional implications.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00429-014-0719-7

Uptake of melatonin into the cerebrospinal fluid after nasal and intravenous delivery: studies in rats and comparison with a human study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00429-014-0719-7

Nocturnal Elevation of Plasma Melatonin and Urinary 5-Hydroxyindoleacetic Acid in Young Men: Attempts at Modification by Brief Changes in Environmental Lighting and Sleep and by Autonomic Drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00429-014-0719-7

Extrapineal melatonin: analysis of its subcellular distribution and daily fluctuations

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00429-014-0719-7

Plasma, cerebrospinal fluid, and brain distribution of 14C-melatonin in rat: a biochemical and autoradiographic study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00429-014-0719-7

Aging-dependent changes of microglial cells and their relevance for neurodegenerative disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00429-014-0719-7

Penetration and removal of horseradish peroxidase injected into the cerebrospinal fluid: role of cerebral perivascular spaces, endothelium and microglia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00429-014-0719-7

Methazolamide and melatonin inhibit mitochondrial cytochrome C release and are neuroprotective in experimental models of ischemic injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00429-014-0719-7

The melatonin MT1 receptor axis modulates mutant Huntingtin-mediated toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00429-014-0719-7

Cytoprotective effects of melatonin on astroglial cells subjected to palmitic acid treatment in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00429-014-0719-7

Reduced oxidative damage in ALS by high-dose enteral melatonin treatment

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00429-014-0719-7

Chronic phase advance alters circadian physiological rhythms and peripheral molecular clocks

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00429-014-0719-7

Melatonin improves D-galactose-induced aging effects on behavior, neurogenesis, and lipid peroxidation in the mouse dentate gyrus via increasing pCREB expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00429-014-0719-7

Effect of Oral Melatonin Administration on Melatonin, 5-Hydroxyindoleacetic Acid, Indoleacetic Acid, and Cyclic Nucleotides in Human Cerebrospinal Fluid

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00429-014-0719-7

Melatonin inhibits the caspase-1/cytochrome c/caspase-3 cell death pathway, inhibits MT1 receptor loss and delays disease progression in a mouse model of amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00429-014-0719-7

Melatonin antagonizes hypoxia-mediated glioblastoma cell migration and invasion via inhibition of HIF-1α.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00429-014-0719-7

Early neuropathological Alzheimer's changes in aged individuals are accompanied by decreased cerebrospinal fluid melatonin levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00429-014-0719-7

10.1007/S00429-014-0719-7

21 January 2018

Identifiers

DOI

1 reference

30 August 2017

1 reference