(Q38197434)

30 August 2017

1 reference

title

Current concepts and clinical applications of stroke genetics (English)

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30 August 2017

3

Martin Dichgans

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30 August 2017

4

Jonathan Rosand

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30 August 2017

2

Rainer Malik

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30 August 2017

1

Guido J Falcone

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30 August 2017

publication date

1 April 2014

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30 August 2017

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30 August 2017

volume

13

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30 August 2017

issue

4

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30 August 2017

page(s)

405-418

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Reengineering translational science: the time is right

30 August 2017

cites work

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7 January 2021

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7 January 2021

Genome-wide association analysis identifies 13 new risk loci for schizophrenia

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7 January 2021

APOE genotype and extent of bleeding and outcome in lobar intracerebral haemorrhage: a genetic association study

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7 January 2021

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7 January 2021

Stroke Genetics Network (SiGN) study: design and rationale for a genome-wide association study of ischemic stroke subtypes

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7 January 2021

Ischaemic stroke: one or several complex genetic disorders?

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7 January 2021

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7 January 2021

Risk factors for intracerebral hemorrhage differ according to hemorrhage location

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7 January 2021

The Causative Classification of Stroke system: an international reliability and optimization study

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7 January 2021

Genomewide association studies and assessment of the risk of disease

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7 January 2021

The complete genome of an individual by massively parallel DNA sequencing

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7 January 2021

In search of low-frequency and rare variants affecting complex traits

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7 January 2021

Recommendations of the National Heart, Lung, and Blood Institute working group on cerebrovascular biology and disease

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7 January 2021

A randomized and clinical effectiveness trial comparing two pharmacogenetic algorithms and standard care for individualizing warfarin dosing (CoumaGen-II).

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7 January 2021

Genotype imputation with thousands of genomes

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7 January 2021

Genotype and SNP calling from next-generation sequencing data

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7 January 2021

Evaluation of coverage variation of SNP chips for genome-wide association studies.

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7 January 2021

Candidate gene association studies: a comprehensive guide to useful in silico tools

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7 January 2021

Designing genome-wide association studies: sample size, power, imputation, and the choice of genotyping chip

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7 January 2021

Best practices and joint calling of the HumanExome BeadChip: the CHARGE Consortium

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7 January 2021

Dense genotyping identifies and localizes multiple common and rare variant association signals in celiac disease

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7 January 2021

The metabochip, a custom genotyping array for genetic studies of metabolic, cardiovascular, and anthropometric traits

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7 January 2021

Genotype imputation for genome-wide association studies

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7 January 2021

Whole exome and whole genome sequencing

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7 January 2021

Detection of clinically relevant genetic variants in autism spectrum disorder by whole-genome sequencing

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7 January 2021

Assumption-free estimation of heritability from genome-wide identity-by-descent sharing between full siblings

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7 January 2021

Association between a literature-based genetic risk score and cardiovascular events in women

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7 January 2021

Heritability in the genomics era — concepts and misconceptions

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7 January 2021

GCTA: a tool for genome-wide complex trait analysis

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https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970029-8

7 January 2021

Heritability estimates identify a substantial genetic contribution to risk and outcome of intracerebral hemorrhage

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https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970029-8

7 January 2021

Genetic heritability of ischemic stroke and the contribution of previously reported candidate gene and genomewide associations

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https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970029-8

7 January 2021

Power and predictive accuracy of polygenic risk scores.

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https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970029-8

7 January 2021

A study of twins and stroke

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https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970029-8

7 January 2021

Systematic review of methods and results of studies of the genetic epidemiology of ischemic stroke

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https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970029-8

7 January 2021

Evaluating the genetic component of ischemic stroke subtypes: a family history study.

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https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970029-8

7 January 2021

Family history in ischemic stroke before 70 years of age: the Sahlgrenska Academy Study on Ischemic Stroke

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7 January 2021

Siblings with ischemic stroke study: results of a genome-wide scan for stroke loci

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7 January 2021

Mendelian etiologies of stroke

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7 January 2021

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7 January 2021

Mitochondrial myopathy, encephalopathy, lactic acidosis, and strokelike episodes: A distinctive clinical syndrome

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7 January 2021

Prevalence of Fabry disease in patients with cryptogenic stroke: a prospective study.

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7 January 2021

Distinct phenotypic and functional features of CADASIL mutations in the Notch3 ligand binding domain

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7 January 2021

Cerebral autosomal recessive arteriopathy with subcortical infarcts and leukoencephalopathy.

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7 January 2021

Heterozygous Fabry women are not just carriers, but have a significant burden of disease and impaired quality of life.

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7 January 2021

Narrative review: Fabry disease

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7 January 2021

Pathophysiology and treatment of stroke in sickle-cell disease: present and future

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7 January 2021

Stroke in young patients with hyperhomocysteinemia due to cystathionine beta-synthase deficiency

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7 January 2021

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7 January 2021

Clinical and genetic features of Ehlers-Danlos syndrome type IV, the vascular type

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7 January 2021

Neurovascular manifestations of heritable connective tissue disorders. A review

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7 January 2021

Clinical features and outcome in North American adults with moyamoya phenomenon

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https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970029-8

7 January 2021

ABO(H) blood groups and vascular disease: a systematic review and meta-analysis.

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https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970029-8

7 January 2021

Risk variants for atrial fibrillation on chromosome 4q25 associate with ischemic stroke.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970029-8

7 January 2021

Variants conferring risk of atrial fibrillation on chromosome 4q25.

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https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970029-8

7 January 2021

The association of the 4q25 susceptibility variant for atrial fibrillation with stroke is limited to stroke of cardioembolic etiology

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https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970029-8

7 January 2021

Independent susceptibility markers for atrial fibrillation on chromosome 4q25.

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https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970029-8

7 January 2021

A sequence variant in ZFHX3 on 16q22 associates with atrial fibrillation and ischemic stroke

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https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970029-8

7 January 2021

Genome-wide association study identifies a variant in HDAC9 associated with large vessel ischemic stroke

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https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970029-8

7 January 2021

Common variants at 6p21.1 are associated with large artery atherosclerotic stroke

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https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970029-8

7 January 2021

Meta-analysis of genome-wide association studies identifies 1q22 as a susceptibility locus for intracerebral hemorrhage

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https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970029-8

7 January 2021

Variants at APOE influence risk of deep and lobar intracerebral hemorrhage

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970029-8

7 January 2021

COL4A1 mutations in patients with sporadic late-onset intracerebral hemorrhage

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https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970029-8

7 January 2021

COL4A2 mutations impair COL4A1 and COL4A2 secretion and cause hemorrhagic stroke

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7 January 2021

Molecular pathway for the localized formation of the sinoatrial node

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7 January 2021

Pitx2 prevents susceptibility to atrial arrhythmias by inhibiting left-sided pacemaker specification

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https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970029-8

7 January 2021

PITX2 insufficiency leads to atrial electrical and structural remodeling linked to arrhythmogenesis

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https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970029-8

7 January 2021

PITX2c Is Expressed in the Adult Left Atrium, and Reducing Pitx2c Expression Promotes Atrial Fibrillation Inducibility and Complex Changes in Gene Expression

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https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970029-8

7 January 2021

A human alpha-fetoprotein enhancer-binding protein, ATBF1, contains four homeodomains and seventeen zinc fingers

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https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970029-8

7 January 2021

A common allele on chromosome 9 associated with coronary heart disease

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https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970029-8

7 January 2021

A common variant on chromosome 9p21 affects the risk of myocardial infarction

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https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970029-8

7 January 2021

Genomewide association analysis of coronary artery disease

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https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970029-8

7 January 2021

The same sequence variant on 9p21 associates with myocardial infarction, abdominal aortic aneurysm and intracranial aneurysm

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https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970029-8

7 January 2021

Shared genetic susceptibility to ischemic stroke and coronary artery disease: a genome-wide analysis of common variants

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https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970029-8

7 January 2021

Mechanisms of sporadic cerebral small vessel disease: insights from neuroimaging

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970029-8

7 January 2021

Genetic susceptibility to thrombosis and its relationship to physiological risk factors: the GAIT study. Genetic Analysis of Idiopathic Thrombophilia

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970029-8

7 January 2021

Ischemic stroke is associated with the ABO locus: the EuroCLOT study

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970029-8

7 January 2021

Common mitochondrial sequence variants in ischemic stroke

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970029-8

7 January 2021

Multilocus genetic risk score associates with ischemic stroke in case-control and prospective cohort studies

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970029-8

7 January 2021

Genome-wide association studies of intracranial aneurysms: an update

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970029-8

7 January 2021

Genetic risk factors for intracranial aneurysms: a meta-analysis in more than 116,000 individuals

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970029-8

7 January 2021

Lacunar strokes and infarcts: a review

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https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970029-8

7 January 2021

The cerebral beta-amyloid angiopathies: hereditary and sporadic

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https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970029-8

7 January 2021

Clinical diagnosis of cerebral amyloid angiopathy: validation of the Boston criteria

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7 January 2021

Genetic and environmental risk factors for intracerebral hemorrhage: preliminary results of a population-based study

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970029-8

7 January 2021

Familial risk of ischemic and hemorrhagic stroke: a large-scale study of the Swedish population.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970029-8

7 January 2021

Cerebral amyloid angiopathy. A critical review

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970029-8

7 January 2021

Hereditary cystatin C amyloid angiopathy: genetic, clinical, and pathological aspects

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970029-8

7 January 2021

Hereditary cerebral hemorrhage with amyloidosis Dutch type (AbetaPP 693): decreased plasma amyloid-beta 42 concentration

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970029-8

7 January 2021

Flemish and Dutch mutations in amyloid beta precursor protein have different effects on amyloid beta secretion

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970029-8

7 January 2021

BACE2, a beta -secretase homolog, cleaves at the beta site and within the amyloid-beta region of the amyloid-beta precursor protein

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970029-8

7 January 2021

Clinical spectrum of type IV collagen (COL4A1) mutations: a novel genetic multisystem disease

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https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970029-8

7 January 2021

Clinical and brain MRI follow-up study of a family with COL4A1 mutation

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970029-8

7 January 2021

Neonatal porencephaly and adult stroke related to mutations in collagen IV A1

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https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970029-8

7 January 2021

The apolipoprotein E epsilon2 allele and the pathological features in cerebral amyloid angiopathy-related hemorrhage.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970029-8

7 January 2021

Role of COL4A1 in small-vessel disease and hemorrhagic stroke.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970029-8

7 January 2021

Genetics of Alzheimer disease

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970029-8

7 January 2021

Genetic variation at CR1 increases risk of cerebral amyloid angiopathy

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970029-8

7 January 2021

Genome-wide association studies of cerebral white matter lesion burden: the CHARGE consortium

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970029-8

7 January 2021

Burden of risk alleles for hypertension increases risk of intracerebral hemorrhage

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970029-8

7 January 2021

Apolipoprotein E genotype predicts hematoma expansion in lobar intracerebral hemorrhage

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970029-8

7 January 2021

Burden of blood pressure-related alleles is associated with larger hematoma volume and worse outcome in intracerebral hemorrhage

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970029-8

7 January 2021

Toward constructing an endophenotype strategy for bipolar disorders

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970029-8

7 January 2021

The clinical importance of white matter hyperintensities on brain magnetic resonance imaging: systematic review and meta-analysis

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970029-8

7 January 2021

Genetic variation in white matter hyperintensity volume in the Framingham Study.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970029-8

7 January 2021

Heritability of leukoaraiosis in hypertensive sibships

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970029-8

7 January 2021

Evidence for genetic variance in white matter hyperintensity volume in normal elderly male twins.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970029-8

7 January 2021

White matter lesions, cognition, and recurrent hemorrhage in lobar intracerebral hemorrhage.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970029-8

7 January 2021

Leukoaraiosis is associated with warfarin-related hemorrhage following ischemic stroke

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970029-8

7 January 2021

Leukoaraiosis Is a Risk Factor for Symptomatic Intracerebral Hemorrhage After Thrombolysis for Acute Stroke

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970029-8

7 January 2021

17q25 Locus is associated with white matter hyperintensity volume in ischemic stroke, but not with lacunar stroke status

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970029-8

7 January 2021

Genetics of ischaemic stroke

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970029-8

7 January 2021

Paediatric stroke: genetic insights into disease mechanisms and treatment targets

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970029-8

7 January 2021

Warfarin and absolute risk of hemorrhagic stroke

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970029-8

7 January 2021

Predictors of hematoma volume in deep and lobar supratentorial intracerebral hemorrhage.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970029-8

7 January 2021

Effect of VKORC1 haplotypes on transcriptional regulation and warfarin dose

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970029-8

7 January 2021

Association of polymorphisms in the cytochrome P450 CYP2C9 with warfarin dose requirement and risk of bleeding complications

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970029-8

7 January 2021

Estimation of the warfarin dose with clinical and pharmacogenetic data

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970029-8

7 January 2021

Warfarin pharmacogenetics: a single VKORC1 polymorphism is predictive of dose across 3 racial groups

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970029-8

7 January 2021

Genetic warfarin dosing: tables versus algorithms.

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https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970029-8

7 January 2021

A randomized trial of genotype-guided dosing of warfarin.

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https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970029-8

7 January 2021

A pharmacogenetic versus a clinical algorithm for warfarin dosing

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https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970029-8

7 January 2021

Personalized approaches to clopidogrel therapy: are we there yet?

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970029-8

7 January 2021

A predictive clinical-genetic model of tissue plasminogen activator response in acute ischemic stroke

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970029-8

7 January 2021

Genetic determinants of dabigatran plasma levels and their relation to bleeding

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970029-8

7 January 2021

Estimation of effect size distribution from genome-wide association studies and implications for future discoveries

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970029-8

7 January 2021

Improving the reliability of stroke subgroup classification using the Trial of ORG 10172 in Acute Stroke Treatment (TOAST) criteria.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970029-8

7 January 2021

A computerized algorithm for etiologic classification of ischemic stroke: the Causative Classification of Stroke System.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970029-8

7 January 2021

NINDS stroke genetics network (SiGN) experience with the causative classification system.

1 reference

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7 January 2021

Uncovering the roles of rare variants in common disease through whole-genome sequencing

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7 January 2021

A decade's perspective on DNA sequencing technology

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7 January 2021

Complement factor H polymorphism in age-related macular degeneration

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7 January 2021

A multilocus genetic risk score for coronary heart disease: case-control and prospective cohort analyses

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https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970029-8

7 January 2021

Impact of inherited genetic variants associated with lipid profile, hypertension, and coronary artery disease on the risk of intracranial and abdominal aortic aneurysms

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https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970029-8

7 January 2021

Large sample size, wide variant spectrum, and advanced machine-learning technique boost risk prediction for inflammatory bowel disease

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7 January 2021

Incremental value of rare genetic variants for the prediction of multifactorial diseases

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7 January 2021

Personalized medicine: potential, barriers and contemporary issues

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7 January 2021

Prenatal assessment of fetal chromosomal and genetic disorders through maternal plasma DNA analysis

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https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970029-8

7 January 2021

Breast and ovarian cancer risks due to inherited mutations in BRCA1 and BRCA2

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https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970029-8

7 January 2021

Stroke genetics: prospects for personalized medicine

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7 January 2021

10.1016/S1474-4422(14)70029-8

Identifiers

DOI

1 reference

30 August 2017

1 reference