(Q38198852)

30 August 2017

title

Gene expression regulation mediated through reversible m⁶A RNA methylation (English)

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30 August 2017

Dan Dominissini

2

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Gidi Rechavi

series ordinal

3

object named as

Gideon Rechavi

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30 August 2017

Ye Fu

1

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30 August 2017

Chuan He

series ordinal

4

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30 August 2017

publication date

25 March 2014

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30 August 2017

published in

Nature Reviews Genetics

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30 August 2017

volume

15

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30 August 2017

issue

5

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30 August 2017

page(s)

293-306

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DNA methylation landscapes: provocative insights from epigenomics

30 August 2017

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31 March 2020

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31 March 2020

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31 March 2020

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RNA nucleotide methylation

31 March 2020

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N6-methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO

31 March 2020

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ALKBH5 is a mammalian RNA demethylase that impacts RNA metabolism and mouse fertility

31 March 2020

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Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq

31 March 2020

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Comprehensive analysis of mRNA methylation reveals enrichment in 3' UTRs and near stop codons

31 March 2020

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Methylated nucleotides block 5' terminus of HeLa cell messenger RNA.

31 March 2020

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Localization of N6-methyladenosine in the Rous sarcoma virus genome

31 March 2020

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Comparison of methylated sequences in messenger RNA and heterogeneous nuclear RNA from mouse L cells

31 March 2020

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Nucleotide sequences at the N6-methyladenosine sites of HeLa cell messenger ribonucleic acid

31 March 2020

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An in vitro system for accurate methylation of internal adenosine residues in messenger RNA

31 March 2020

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Context effects on N6-adenosine methylation sites in prolactin mRNA.

31 March 2020

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Sequences containing methylated nucleotides at the 5' termini of messenger RNAs: possible implications for processing

31 March 2020

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Yeast targets for mRNA methylation

31 March 2020

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Mobilities of modified ribonucleotides on two-dimensional cellulose thin-layer chromatography

31 March 2020

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Induction of sporulation in Saccharomyces cerevisiae leads to the formation of N6-methyladenosine in mRNA: a potential mechanism for the activity of the IME4 gene

31 March 2020

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High-resolution mapping reveals a conserved, widespread, dynamic mRNA methylation program in yeast meiosis

31 March 2020

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Probing N6-methyladenosine RNA modification status at single nucleotide resolution in mRNA and long noncoding RNA

31 March 2020

1 reference

N6-methyladenosine residues in an intron-specific region of prolactin pre-mRNA.

31 March 2020

1 reference

The thermodynamic stability of RNA duplexes and hairpins containing N6-alkyladenosines and 2-methylthio-N6-alkyladenosines

31 March 2020

1 reference

Identification of a selective polymerase enables detection of N(6)-methyladenosine in RNA.

31 March 2020

1 reference

Analysis of RNA base modification and structural rearrangement by single-molecule real-time detection of reverse transcription

31 March 2020

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The biosynthesis and functional roles of methylated nucleosides in eukaryotic mRNA

31 March 2020

1 reference

A METTL3-METTL14 complex mediates mammalian nuclear RNA N6-adenosine methylation

31 March 2020

1 reference

Structure prediction and phylogenetic analysis of a functionally diverse family of proteins homologous to the MT-A70 subunit of the human mRNA:m(6)A methyltransferase

31 March 2020

1 reference

N6-methyladenosine modification destabilizes developmental regulators in embryonic stem cells

31 March 2020

1 reference

Two proteins that form a complex are required for 7-methylguanosine modification of yeast tRNA.

31 March 2020

1 reference

Trmt61B is a methyltransferase responsible for 1-methyladenosine at position 58 of human mitochondrial tRNAs

31 March 2020

1 reference

The bipartite structure of the tRNA m1A58 methyltransferase from S. cerevisiae is conserved in humans

31 March 2020

1 reference

Structure of the yeast tRNA m7G methylation complex

31 March 2020

1 reference

MTA is an Arabidopsis messenger RNA adenosine methylase and interacts with a homolog of a sex-specific splicing factor

31 March 2020

1 reference

RNA methylation by the MIS complex regulates a cell fate decision in yeast

31 March 2020

1 reference

Identification of WTAP, a novel Wilms' tumour 1-associating protein

31 March 2020

1 reference

Mammalian WTAP is a regulatory subunit of the RNA N6-methyladenosine methyltransferase

31 March 2020

1 reference

Identification of Wilms' tumor 1-associating protein complex and its role in alternative splicing and the cell cycle

31 March 2020

1 reference

Adenosine Methylation in Arabidopsis mRNA is Associated with the 3' End and Reduced Levels Cause Developmental Defects

31 March 2020

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Drosophila Inducer of MEiosis 4 (IME4) is required for Notch signaling during oogenesis

31 March 2020

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31 March 2020

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Variation in FTO contributes to childhood obesity and severe adult obesity

31 March 2020

1 reference

A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity

31 March 2020

1 reference

Genome-wide association scan shows genetic variants in the FTO gene are associated with obesity-related traits

31 March 2020

1 reference

The obesity-associated FTO gene encodes a 2-oxoglutarate-dependent nucleic acid demethylase

31 March 2020

1 reference

Inactivation of the Fto gene protects from obesity

31 March 2020

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Overexpression of Fto leads to increased food intake and results in obesity

31 March 2020

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Loss-of-function mutation in the dioxygenase-encoding FTO gene causes severe growth retardation and multiple malformations

31 March 2020

1 reference

Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA

31 March 2020

1 reference

Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine

31 March 2020

1 reference

Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1

31 March 2020

1 reference

Oxidative demethylation of 3-methylthymine and 3-methyluracil in single-stranded DNA and RNA by mouse and human FTO

31 March 2020

1 reference

The fat mass and obesity associated gene (Fto) regulates activity of the dopaminergic midbrain circuitry

31 March 2020

1 reference

Role for the obesity-related FTO gene in the cellular sensing of amino acids

31 March 2020

1 reference

Crystal structure of the FTO protein reveals basis for its substrate specificity

31 March 2020

1 reference

Sprouts of RNA epigenetics: the discovery of mammalian RNA demethylases.

31 March 2020

1 reference

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts

31 March 2020

1 reference

FTO-mediated formation of N6-hydroxymethyladenosine and N6-formyladenosine in mammalian RNA.

31 March 2020

1 reference

Global quantification of mammalian gene expression control

31 March 2020

1 reference

Metabolic labeling of RNA uncovers principles of RNA production and degradation dynamics in mammalian cells

31 March 2020

1 reference

The FTO Gene, Implicated in Human Obesity, Is Found Only in Vertebrates and Marine Algae

31 March 2020

1 reference

Prediction of novel families of enzymes involved in oxidative and other complex modifications of bases in nucleic acids

31 March 2020

1 reference

N6-methyladenosine-dependent regulation of messenger RNA stability

31 March 2020

1 reference

Regulation of cytoplasmic mRNA decay

31 March 2020

1 reference

The multiple lives of NMD factors: balancing roles in gene and genome regulation

31 March 2020

1 reference

Decapping and Decay of Messenger RNA Occur in Cytoplasmic Processing Bodies

31 March 2020

1 reference

IRE1alpha kinase activation modes control alternate endoribonuclease outputs to determine divergent cell fates.

31 March 2020

1 reference

Metabolism and regulation of canonical histone mRNAs: life without a poly(A) tail

31 March 2020

1 reference

The importance of CELF control: molecular and biological roles of the CUG-BP, Elav-like family of RNA-binding proteins

31 March 2020

1 reference

Endonuclease-mediated mRNA decay involves the selective targeting of PMR1 to polyribosome-bound substrate mRNA.

31 March 2020

1 reference

RNA decay modulates gene expression and controls its fidelity

31 March 2020

1 reference

MicroRNAs: small RNAs with a big role in gene regulation

31 March 2020

1 reference

Diversifying microRNA sequence and function

31 March 2020

1 reference

Selective elimination of messenger RNA prevents an incidence of untimely meiosis

31 March 2020

1 reference

Suppression of RNA recognition by Toll-like receptors: the impact of nucleoside modification and the evolutionary origin of RNA

31 March 2020

1 reference

Toll-like receptor and RIG-I-like receptor signaling

31 March 2020

1 reference

Sculpting of the spliceosomal branch site recognition motif by a conserved pseudouridine

31 March 2020

1 reference

Transcriptome-wide analysis of regulatory interactions of the RNA-binding protein HuR.

31 March 2020

1 reference

Integrative regulatory mapping indicates that the RNA-binding protein HuR couples pre-mRNA processing and mRNA stability

31 March 2020

1 reference

UneCLIPsing HuR nuclear function

31 March 2020

1 reference

HuR and miR-1192 regulate myogenesis by modulating the translation of HMGB1 mRNA

31 March 2020

1 reference

Changes in cellular mRNA stability, splicing, and polyadenylation through HuR protein sequestration by a cytoplasmic RNA virus

31 March 2020

1 reference

Posttranscriptional regulation of cancer traits by HuR

31 March 2020

1 reference

The functions of animal microRNAs

31 March 2020

1 reference

The evolution of gene regulation by transcription factors and microRNAs

31 March 2020

1 reference

Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight?

31 March 2020

1 reference

P bodies and the control of mRNA translation and degradation

31 March 2020

1 reference

RNA regulons: coordination of post-transcriptional events

31 March 2020

1 reference

Post-translational modifications regulate the ticking of the circadian clock.

31 March 2020

1 reference

P bodies: at the crossroads of post-transcriptional pathways

31 March 2020

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RNA-methylation-dependent RNA processing controls the speed of the circadian clock

31 March 2020

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Primate transcript and protein expression levels evolve under compensatory selection pressures

31 March 2020

1 reference

Variation and genetic control of protein abundance in humans

31 March 2020

1 reference

The birth of the Epitranscriptome: deciphering the function of RNA modifications

31 March 2020

1 reference

Converting nonsense codons into sense codons by targeted pseudouridylation

31 March 2020

1 reference

Unusual base pairing during the decoding of a stop codon by the ribosome

31 March 2020

1 reference

RNA pseudouridylation: new insights into an old modification

31 March 2020

1 reference

Transcriptome-wide mapping of 5-methylcytidine RNA modifications in bacteria, archaea, and yeast reveals m5C within archaeal mRNAs

31 March 2020

1 reference

Characterizing 5-methylcytosine in the mammalian epitranscriptome

31 March 2020

1 reference

Widespread occurrence of 5-methylcytosine in human coding and non-coding RNA

31 March 2020

1 reference

Missense mutation in pseudouridine synthase 1 (PUS1) causes mitochondrial myopathy and sideroblastic anemia (MLASA).

31 March 2020

1 reference

Mitochondrial myopathy and sideroblastic anemia (MLASA): missense mutation in the pseudouridine synthase 1 (PUS1) gene is associated with the loss of tRNA pseudouridylation

31 March 2020

1 reference

Prader-Willi phenotype caused by paternal deficiency for the HBII-85 C/D box small nucleolar RNA cluster

31 March 2020

1 reference

Repairing DNA-methylation damage

31 March 2020

1 reference

Direct reversal of DNA alkylation damage

31 March 2020

1 reference

The AlkB domain of mammalian ABH8 catalyzes hydroxylation of 5-methoxycarbonylmethyluridine at the wobble position of tRNA

31 March 2020

1 reference

ALKBH8-mediated formation of a novel diastereomeric pair of wobble nucleosides in mammalian tRNA

31 March 2020

1 reference

Structure of human RNA N6-methyladenine demethylase ALKBH5 provides insights into its mechanisms of nucleic acid recognition and demethylation

31 March 2020

1 reference

Crystal structure of the RNA demethylase ALKBH5 from zebrafish

31 March 2020

1 reference

Purification and cDNA cloning of the AdoMet-binding subunit of the human mRNA (N6-adenosine)-methyltransferase

31 March 2020

1 reference

12 December 2020

Influenza viral mRNA contains internal N6-methyladenosine and 5'-terminal 7-methylguanosine in cap structures

1 reference

12 December 2020

Cloning of Fatso (Fto), a novel gene deleted by the Fused toes (Ft) mouse mutation

1 reference

12 December 2020

Nucleotide Methylation Patterns in Eukaryotic mRNA

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12 December 2020

Sequence specificity of mRNA N6-adenosine methyltransferase

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12 December 2020

Identifiers

DOI

10.1038/NRG3724

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Dimensions Publication ID

30 August 2017

1004136167

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