(Q38201247)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24691255%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

title

The biogenesis of chromosome translocations (English)

1 reference

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12 March 2020

publication date

1 April 2014

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24691255%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24691255%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

volume

16

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12 March 2020

issue

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24691255%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

page(s)

293-300

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24691255%20AND%20SRC:MED&resulttype=core&format=json

Massive genomic rearrangement acquired in a single catastrophic event during cancer development

12 March 2020

cites work

1 reference

The impact of translocations and gene fusions on cancer causation

21 January 2018

1 reference

Spatial genome organization in the formation of chromosomal translocations

21 January 2018

1 reference

Mechanism and control of V(D)J recombination versus class switch recombination: similarities and differences

21 January 2018

1 reference

The mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathway

21 January 2018

1 reference

More than just a focus: The chromatin response to DNA damage and its role in genome integrity maintenance

21 January 2018

1 reference

Imaging of protein movement induced by chromosomal breakage: tiny 'local' lesions pose great 'global' challenges

21 January 2018

1 reference

DNA breaks promote genomic instability by impeding proper chromosome segregation.

21 January 2018

1 reference

Positional stability of single double-strand breaks in mammalian cells

21 January 2018

1 reference

Changes in chromatin structure and mobility in living cells at sites of DNA double-strand breaks

21 January 2018

1 reference

Live cell microscopy analysis of radiation-induced DNA double-strand break motion.

21 January 2018

1 reference

In situ visualization of DNA double-strand break repair in human fibroblasts

21 January 2018

1 reference

Dynamics of DNA double-strand breaks revealed by clustering of damaged chromosome domains.

21 January 2018

1 reference

Chromatin mobility is increased at sites of DNA double-strand breaks

21 January 2018

1 reference

Increased mobility of double-strand breaks requires Mec1, Rad9 and the homologous recombination machinery.

21 January 2018

1 reference

Cohesin and the nucleolus constrain the mobility of spontaneous repair foci

21 January 2018

1 reference

Checkpoint kinases and the INO80 nucleosome remodeling complex enhance global chromatin mobility in response to DNA damage.

21 January 2018

1 reference

53BP1 promotes non-homologous end joining of telomeres by increasing chromatin mobility

21 January 2018

1 reference

Beyond the sequence: cellular organization of genome function

21 January 2018

1 reference

The cellular etiology of chromosome translocations.

21 January 2018

1 reference

Influences of chromosome size, gene density and nuclear position on the frequency of constitutional translocations in the human population

21 January 2018

1 reference

Conservation of relative chromosome positioning in normal and cancer cells

21 January 2018

1 reference

Intermingling of chromosome territories in interphase suggests role in translocations and transcription-dependent associations

21 January 2018

1 reference

Structural basis for Robertsonian translocations in man: association of ribosomal genes in the nucleolar fibrillar center in meiotic spermatocytes and oocytes

21 January 2018

1 reference

Chromosome territories, nuclear architecture and gene regulation in mammalian cells

21 January 2018

1 reference

Tissue-specific spatial organization of genomes

21 January 2018

1 reference

Effect of nuclear architecture on the efficiency of double-strand break repair

21 January 2018

1 reference

Genome-wide translocation sequencing reveals mechanisms of chromosome breaks and rearrangements in B cells

21 January 2018

1 reference

Translocation-capture sequencing reveals the extent and nature of chromosomal rearrangements in B lymphocytes

21 January 2018

1 reference

Spatial organization of the mouse genome and its role in recurrent chromosomal translocations

21 January 2018

1 reference

Close proximity to Igh is a contributing factor to AID-mediated translocations.

21 January 2018

1 reference

Spatial dynamics of chromosome translocations in living cells.

21 January 2018

1 reference

Long-range directional movement of an interphase chromosome site

21 January 2018

1 reference

Actin-dependent intranuclear repositioning of an active gene locus in vivo.

21 January 2018

1 reference

Chromatin movement in the maintenance of genome stability.

21 January 2018

1 reference

Principles of chromosomal organization: lessons from yeast

21 January 2018

1 reference

The budding yeast nucleus.

21 January 2018

1 reference

Chromatin motion is constrained by association with nuclear compartments in human cells.

21 January 2018

1 reference

Chromatin movement visualized with photoactivable GFP-labeled histone H4.

21 January 2018

1 reference

Chromosome order in HeLa cells changes during mitosis and early G1, but is stably maintained during subsequent interphase stages.

21 January 2018

1 reference

The radial positioning of chromatin is not inherited through mitosis but is established de novo in early G1.

21 January 2018

1 reference

Chromosome dynamics in the yeast interphase nucleus

21 January 2018

1 reference

Chromatin dynamics is correlated with replication timing

21 January 2018

1 reference

Single-molecule imaging of DNA pairing by RecA reveals a three-dimensional homology search

21 January 2018

1 reference

RecA filament sliding on DNA facilitates homology search

21 January 2018

1 reference

Homologous chromosomes make contact at the sites of double-strand breaks in genes in somatic G0/G1-phase human cells

21 January 2018

1 reference

Colocalization of multiple DNA double-strand breaks at a single Rad52 repair centre

21 January 2018

1 reference

The Smc5-Smc6 complex and SUMO modification of Rad52 regulates recombinational repair at the ribosomal gene locus.

21 January 2018

1 reference

Double-strand breaks in heterochromatin move outside of a dynamic HP1a domain to complete recombinational repair.

21 January 2018

1 reference

DNA double-strand breaks in heterochromatin elicit fast repair protein recruitment, histone H2AX phosphorylation and relocation to euchromatin

21 January 2018

1 reference

Heterochromatin is refractory to gamma-H2AX modification in yeast and mammals

21 January 2018

1 reference

Molecular pathways: transcription factories and chromosomal translocations.

21 January 2018

1 reference

Myc dynamically and preferentially relocates to a transcription factory occupied by Igh

21 January 2018

1 reference

Identification of early replicating fragile sites that contribute to genome instability

21 January 2018

1 reference

Nuclear receptor-induced chromosomal proximity and DNA breaks underlie specific translocations in cancer

21 January 2018

1 reference

Gene deregulation and spatial genome reorganization near breakpoints prior to formation of translocations in anaplastic large cell lymphoma

21 January 2018

1 reference

A forward chemical genetic screen reveals an inhibitor of the Mre11-Rad50-Nbs1 complex

21 January 2018

1 reference

The MRE11 complex: starting from the ends.

21 January 2018

1 reference

The DNA double-strand break repair gene hMRE11 is mutated in individuals with an ataxia-telangiectasia-like disorder

21 January 2018

1 reference

Mre11 Dimers Coordinate DNA End Bridging and Nuclease Processing in Double-Strand-Break Repair

21 January 2018

1 reference

Multiple functions of MRN in end-joining pathways during isotype class switching

21 January 2018

1 reference

MRN complex function in the repair of chromosomal Rag-mediated DNA double-strand breaks

21 January 2018

1 reference

Role of Mre11 in chromosomal nonhomologous end joining in mammalian cells

21 January 2018

1 reference

Role of mammalian Mre11 in classical and alternative nonhomologous end joining

21 January 2018

1 reference

Human Mre11/human Rad50/Nbs1 and DNA ligase IIIalpha/XRCC1 protein complexes act together in an alternative nonhomologous end joining pathway

21 January 2018

1 reference

Cell cycle and genetic requirements of two pathways of nonhomologous end-joining repair of double-strand breaks in Saccharomyces cerevisiae

21 January 2018

1 reference

The nonhomologous end-joining pathway of DNA repair is required for genomic stability and the suppression of translocations

21 January 2018

1 reference

DNA repair protein Ku80 suppresses chromosomal aberrations and malignant transformation

21 January 2018

1 reference

Interplay of p53 and DNA-repair protein XRCC4 in tumorigenesis, genomic stability and development

21 January 2018

1 reference

Cathepsin L activity controls adipogenesis and glucose tolerance

21 January 2018

1 reference

Alternative end-joining is suppressed by the canonical NHEJ component Xrcc4-ligase IV during chromosomal translocation formation

21 January 2018

1 reference

Identification of a Saccharomyces cerevisiae Ku80 homologue: roles in DNA double strand break rejoining and in telomeric maintenance

21 January 2018

1 reference

Yeast Mre11 and Rad1 proteins define a Ku-independent mechanism to repair double-strand breaks lacking overlapping end sequences

21 January 2018

1 reference

Evidence for replicative repair of DNA double-strand breaks leading to oncogenic translocation and gene amplification

21 January 2018

1 reference

Unrepaired DNA breaks in p53-deficient cells lead to oncogenic gene amplification subsequent to translocations.

21 January 2018

1 reference

Alternative end-joining catalyzes class switch recombination in the absence of both Ku70 and DNA ligase 4.

21 January 2018

1 reference

Human DNA ligases I and III, but not ligase IV, are required for microhomology-mediated end joining of DNA double-strand breaks

21 January 2018

1 reference

DNA ligase III promotes alternative nonhomologous end-joining during chromosomal translocation formation

21 January 2018

1 reference

An essential role for CtIP in chromosomal translocation formation through an alternative end-joining pathway

21 January 2018

1 reference

A structural model for regulation of NHEJ by DNA-PKcs autophosphorylation

21 January 2018

1 reference

Choosing the right path: does DNA-PK help make the decision?

21 January 2018

1 reference

Autophosphorylation of DNA-PKCS regulates its dynamics at DNA double-strand breaks

21 January 2018

1 reference

How shelterin protects mammalian telomeres

21 January 2018

1 reference

Telomere dysfunction promotes non-reciprocal translocations and epithelial cancers in mice

21 January 2018

1 reference

Mechanisms of change in gene copy number

21 January 2018

1 reference

Segmental duplications arise from Pol32-dependent repair of broken forks through two alternative replication-based mechanisms

21 January 2018

1 reference

Frequent chromosomal translocations induced by DNA double-strand breaks

21 January 2018

1 reference

Lack of chromosome territoriality in yeast: promiscuous rejoining of broken chromosome ends.

21 January 2018

1 reference

A model of oncogenic rearrangements: differences between chromosomal translocation mechanisms and simple double-strand break repair

21 January 2018

1 reference

Constitutional chromothripsis rearrangements involve clustered double-stranded DNA breaks and nonhomologous repair mechanisms

21 January 2018

1 reference

Complex reorganization and predominant non-homologous repair following chromosomal breakage in karyotypically balanced germline rearrangements and transgenic integration

21 January 2018

1 reference

Chromosome catastrophes involve replication mechanisms generating complex genomic rearrangements

21 January 2018

1 reference

A DNA replication mechanism for generating nonrecurrent rearrangements associated with genomic disorders

21 January 2018

1 reference

A microhomology-mediated break-induced replication model for the origin of human copy number variation

21 January 2018

1 reference

Homologous recombination and non-homologous end-joining pathways of DNA double-strand break repair have overlapping roles in the maintenance of chromosomal integrity in vertebrate cells

21 January 2018

1 reference

Modeling oncogenic translocations: distinct roles for double-strand break repair pathways in translocation formation in mammalian cells

21 January 2018

1 reference

DNA repair by nonhomologous end joining and homologous recombination during cell cycle in human cells

21 January 2018

1 reference

Double-strand break end resection and repair pathway choice

21 January 2018

1 reference

Dynamics of DNA damage response proteins at DNA breaks: a focus on protein modifications

21 January 2018

1 reference

The emerging role of nuclear architecture in DNA repair and genome maintenance

21 January 2018

1 reference

Chromatin remodeling at DNA double-strand breaks

21 January 2018

1 reference

Prime, repair, restore: the active role of chromatin in the DNA damage response

21 January 2018

1 reference

The dangers of transcription.

21 January 2018

1 reference

A plant homeodomain in RAG-2 that binds Hypermethylated lysine 4 of histone H3 is necessary for efficient antigen-receptor-gene rearrangement

21 January 2018

1 reference

RAG2 PHD finger couples histone H3 lysine 4 trimethylation with V(D)J recombination

21 January 2018

1 reference

Nonimmunoglobulin target loci of activation-induced cytidine deaminase (AID) share unique features with immunoglobulin genes

21 January 2018

1 reference

The genomic complexity of primary human prostate cancer

21 January 2018

1 reference

Targeted INO80 enhances subnuclear chromatin movement and ectopic homologous recombination

21 January 2018

1 reference

Chromosome Fragmentation after Induction of a Double-Strand Break Is an Active Process Prevented by the RMX Repair Complex

21 January 2018

2 references

21 January 2018

12 December 2020

Proximity ofTPRandNTRK1Rearranging Loci in Human Thyrocytes

1 reference

Multiple pathways of recombination induced by double-strand breaks in Saccharomyces cerevisiae

21 January 2018

1 reference

12 December 2020

Chromosomal breakpoint positions suggest a direct role for radiation in inducing illegitimate recombination between the ELE1 and RET genes in radiation-induced thyroid carcinomas

1 reference

12 December 2020

Proximity of chromosomal loci that participate in radiation-induced rearrangements in human cells

1 reference

12 December 2020

Live imaging of telomeres: yKu and Sir proteins define redundant telomere-anchoring pathways in yeast

1 reference

12 December 2020

Spatial proximity of translocation-prone gene loci in human lymphomas

1 reference

12 December 2020

Chromosomal translocation mechanisms at intronic alu elements in mammalian cells

1 reference

12 December 2020

Cell signaling. Nuclear actin as choreographer of cell morphology and transcription

1 reference

12 December 2020

Formation of NHEJ-derived reciprocal chromosomal translocations does not require Ku70.

1 reference

12 December 2020

Higher-order genome organization in human disease

1 reference

12 December 2020

DNA damage defines sites of recurrent chromosomal translocations in B lymphocytes

1 reference

12 December 2020

Increased chromosome mobility facilitates homology search during recombination

1 reference

12 December 2020

Monitoring homology search during DNA double-strand break repair in vivo

1 reference

12 December 2020

Saccharomyces cerevisiae Ku70 potentiates illegitimate DNA double-strand break repair and serves as a barrier to error-prone DNA repair pathways

1 reference

12 December 2020

Localisation and distance between ABL and BCR genes in interphase nuclei of bone marrow cells of control donors and patients with chronic myeloid leukaemia

1 reference

12 December 2020

The nuclear topography of ABL, BCR, PML, and RARalpha genes: evidence for gene proximity in specific phases of the cell cycle and stages of hematopoietic differentiation

1 reference

12 December 2020

Identifiers

DOI

10.1038/NCB2941

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24691255%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

12 March 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24691255%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

PubMed publication ID

24691255

1 reference