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English
Generation of the Cdk5 activator p25 is a memory mechanism that is affected in early Alzheimer's disease.
scientific article published on May 2014
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scholarly article
1 reference
stated in
Europe PubMed Central
PMCID
4013459
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24822036%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 March 2020
title
Generation of the Cdk5 activator p25 is a memory mechanism that is affected in early Alzheimer's disease
(English)
1 reference
stated in
Europe PubMed Central
PMCID
4013459
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24822036%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 March 2020
main subject
Alzheimer's disease
0 references
author
Karl Peter Giese
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMCID
4013459
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24822036%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 March 2020
author name string
K Peter Giese
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMCID
4013459
retrieved
31 August 2017
publication date
1 May 2014
1 reference
stated in
Europe PubMed Central
PMCID
4013459
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24822036%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 March 2020
published in
Frontiers in Molecular Neuroscience
1 reference
stated in
Europe PubMed Central
PMCID
4013459
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24822036%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 March 2020
volume
7
1 reference
stated in
Europe PubMed Central
PMCID
4013459
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24822036%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 March 2020
page(s)
36
1 reference
stated in
Europe PubMed Central
PMCID
4013459
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24822036%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 March 2020
cites work
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PubMed Central
reference URL
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Apolipoprotein E4 effects in Alzheimer's disease are mediated by synaptotoxic oligomeric amyloid-β
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Schizophrenia is associated with dysregulation of a Cdk5 activator that regulates synaptic protein expression and cognition
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PubMed Central
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The GSK3 hypothesis of Alzheimer's disease
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6 September 2017
Role of Septin cytoskeleton in spine morphogenesis and dendrite development in neurons
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Cyclin-dependent kinase 5 in synaptic plasticity, learning and memory.
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6 September 2017
Is there a role of the cyclin-dependent kinase 5 activator p25 in Alzheimer's disease?
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013459
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6 September 2017
Differential roles of nuclear and cytoplasmic cyclin-dependent kinase 5 in apoptotic and excitotoxic neuronal death
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Alzheimer's disease is a synaptic failure
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6 September 2017
A survey of Cdk5 activator p35 and p25 levels in Alzheimer's disease brains
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013459
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6 September 2017
Conversion of p35 to p25 deregulates Cdk5 activity and promotes neurodegeneration
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013459
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6 September 2017
Interplay between cyclin-dependent kinase 5 and glycogen synthase kinase 3 beta mediated by neuregulin signaling leads to differential effects on tau phosphorylation and amyloid precursor protein processing.
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reference URL
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14 September 2017
Cyclin-dependent kinase 5 activator p25 is generated during memory formation and is reduced at an early stage in Alzheimer's disease.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013459
retrieved
31 August 2018
Comparison of a protein-level and peptide-level labeling strategy for quantitative proteomics of synaptosomes using isobaric tags
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013459
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31 August 2018
The roles of cyclin-dependent kinase 5 and glycogen synthase kinase 3 in tau hyperphosphorylation.
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013459
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31 August 2018
Opposing roles of transient and prolonged expression of p25 in synaptic plasticity and hippocampus-dependent memory.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013459
retrieved
31 August 2018
Sexual dimorphisms in the effect of low-level p25 expression on synaptic plasticity and memory.
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stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013459
retrieved
31 August 2018
Improved reversal learning and altered fear conditioning in transgenic mice with regionally restricted p25 expression.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013459
retrieved
31 August 2018
Brain levels of CDK5 activator p25 are not increased in Alzheimer's or other neurodegenerative diseases with neurofibrillary tangles.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013459
retrieved
31 August 2018
Calpain-mediated degradation of p35 to p25 in postmortem human and rat brains.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013459
retrieved
31 August 2018
Neurobiology: p25 protein in neurodegeneration
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.3389%2FFNMOL.2014.00036
retrieved
21 January 2018
Calpain-dependent proteolytic cleavage of the p35 cyclin-dependent kinase 5 activator to p25
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24822036
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
The GTP-binding protein Septin 7 is critical for dendrite branching and dendritic-spine morphology
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24822036
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.3389/FNMOL.2014.00036
1 reference
stated in
Europe PubMed Central
PMCID
4013459
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24822036%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 March 2020
Fatcat ID
release_je5nffpfn5errensr4vxmot7je
1 reference
stated in
Fatcat
reference URL
https://api.fatcat.wiki/v0/release/je5nffpfn5errensr4vxmot7je
retrieved
24 November 2022
based on heuristic
mapped directly with Wikidata item
PMCID
4013459
1 reference
stated in
Europe PubMed Central
PMCID
4013459
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24822036%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 March 2020
PubMed ID
24822036
1 reference
stated in
Europe PubMed Central
PMCID
4013459
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24822036%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 March 2020
ResearchGate publication ID
262267632
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