(Q38215034)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24862830%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

title

Is it time to test biguanide metformin in the treatment of melanoma? (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24862830%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

1 reference

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24862830%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

author name string

Michael Cerezo

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24862830%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

Tijana Tomic

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24862830%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

Stéphane Rocchi

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24862830%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

publication date

26 June 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24862830%20AND%20SRC:MED&resulttype=core&format=json

Pigment Cell & Melanoma Research

19 March 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24862830%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

volume

28

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24862830%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24862830%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

page(s)

8-20

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24862830%20AND%20SRC:MED&resulttype=core&format=json

Nonenzymatic glycosylation of erythrocytic proteins in normal and diabetic subjects. Enzymes of nucleoside and nucleotide metabolism

19 March 2020

cites work

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Avoiding hypoglycaemia while achieving good glycaemic control in type 2 diabetes through optimal use of oral agent therapy

21 January 2018

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The antidiabetic drug metformin exerts an antitumoral effect in vitro and in vivo through a decrease of cyclin D1 level.

21 January 2018

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Targeting cancer cell metabolism: the combination of metformin and 2-deoxyglucose induces p53-dependent apoptosis in prostate cancer cells

21 January 2018

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Increased cancer-related mortality for patients with type 2 diabetes who use sulfonylureas or insulin

21 January 2018

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Systemic treatment with the antidiabetic drug metformin selectively impairs p53-deficient tumor cell growth

21 January 2018

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Metformin is a potent inhibitor of endometrial cancer cell proliferation--implications for a novel treatment strategy

21 January 2018

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Metformin blocks melanoma invasion and metastasis development in AMPK/p53-dependent manner.

21 January 2018

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The influence of glucose-lowering therapies on cancer risk in type 2 diabetes

21 January 2018

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Regulation of insulin receptor substrate-1 by mTORC2 (mammalian target of rapamycin complex 2)

21 January 2018

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Metformin inhibits mammalian target of rapamycin-dependent translation initiation in breast cancer cells

21 January 2018

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Understanding the benefit of metformin use in cancer treatment

21 January 2018

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Dimethylbiguanide inhibits cell respiration via an indirect effect targeted on the respiratory chain complex I.

21 January 2018

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New insights into the mechanisms of macroautophagy in mammalian cells

21 January 2018

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Metformin and reduced risk of cancer in diabetic patients

21 January 2018

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Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state

21 January 2018

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Insulin-lowering effects of metformin in women with early breast cancer

21 January 2018

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In vitro metformin anti-neoplastic activity in epithelial ovarian cancer.

21 January 2018

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Apoptosis. Death deceiver.

21 January 2018

1 reference

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Defining the role of mTOR in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12267

AMPK phosphorylation of raptor mediates a metabolic checkpoint

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12267

AMPK: a key regulator of energy balance in the single cell and the whole organism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12267

AMPK: a key sensor of fuel and energy status in skeletal muscle

21 January 2018

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A serine/threonine kinase gene defective in Peutz-Jeghers syndrome

21 January 2018

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Metformin inhibits the inflammatory response associated with cellular transformation and cancer stem cell growth

21 January 2018

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Cancer stem cells versus phenotype-switching in melanoma

21 January 2018

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Activation of AMP-activated protein kinase leads to the phosphorylation of elongation factor 2 and an inhibition of protein synthesis

21 January 2018

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Metformin Suppresses Colorectal Aberrant Crypt Foci in a Short-term Clinical Trial

21 January 2018

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Important role of the LKB1-AMPK pathway in suppressing tumorigenesis in PTEN-deficient mice

21 January 2018

1 reference

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TSC2 integrates Wnt and energy signals via a coordinated phosphorylation by AMPK and GSK3 to regulate cell growth

21 January 2018

1 reference

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Dual antiglioma action of metformin: cell cycle arrest and mitochondria-dependent apoptosis.

21 January 2018

1 reference

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Role for Rab7 in maturation of late autophagic vacuoles

21 January 2018

1 reference

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In vitro and in vivo anti-melanoma action of metformin.

21 January 2018

1 reference

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AMP-activated protein kinase induces a p53-dependent metabolic checkpoint

21 January 2018

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LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

21 January 2018

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Metformin, independent of AMPK, inhibits mTORC1 in a rag GTPase-dependent manner

21 January 2018

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Metformin-induced stimulation of AMP-activated protein kinase in beta-cells impairs their glucose responsiveness and can lead to apoptosis

21 January 2018

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A possible linkage between AMP-activated protein kinase (AMPK) and mammalian target of rapamycin (mTOR) signalling pathway

21 January 2018

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21 January 2018

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Tumor cell metabolism: cancer's Achilles' heel

21 January 2018

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Characterization of 5'AMP-activated protein kinase activity in the heart and its role in inhibiting acetyl-CoA carboxylase during reperfusion following ischemia

21 January 2018

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Fatty-acid synthase and human cancer: new perspectives on its role in tumor biology

21 January 2018

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The role of autophagy during the early neonatal starvation period

21 January 2018

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Ulk1 plays a critical role in the autophagic clearance of mitochondria and ribosomes during reticulocyte maturation

21 January 2018

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Development by self-digestion: molecular mechanisms and biological functions of autophagy

21 January 2018

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The energy sensing LKB1-AMPK pathway regulates p27(kip1) phosphorylation mediating the decision to enter autophagy or apoptosis

21 January 2018

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New users of metformin are at low risk of incident cancer: a cohort study among people with type 2 diabetes

21 January 2018

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LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1

21 January 2018

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The impact of new insights and revised practice guidelines on prescribing drugs in the treatment of Type 2 diabetes mellitus

21 January 2018

1 reference

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AMPK as a metabolic tumor suppressor: control of metabolism and cell growth

21 January 2018

1 reference

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Control of autophagy by oncogenes and tumor suppressor genes

21 January 2018

1 reference

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Antidiabetic drug metformin induces apoptosis in human MCF breast cancer via targeting ERK signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12267

Metformin accelerates the growth of BRAF V600E-driven melanoma by upregulating VEGF-A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12267

Overview of macroautophagy regulation in mammalian cells

21 January 2018

1 reference

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Autophagy: regulation and role in disease

21 January 2018

1 reference

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Metformin Prevents Tobacco Carcinogen–Induced Lung Tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12267

A protein conjugation system essential for autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12267

Drug therapy of non-insulin-dependent diabetes mellitus in the elderly

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12267

AMP-activated protein kinase (AMPK) signaling in endothelial cells is essential for angiogenesis in response to hypoxic stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12267

Combination therapy with vemurafenib (PLX4032/RG7204) and metformin in melanoma cell lines with distinct driver mutations

21 January 2018

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Hyperinsulinemia and type 2 diabetes: impact on cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12267

Secretome from senescent melanoma engages the STAT3 pathway to favor reprogramming of naive melanoma towards a tumor-initiating cell phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12267

Activation of AMP-activated protein kinase induces p53-dependent apoptotic cell death in response to energetic stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12267

Genome-wide inhibitory impact of the AMPK activator metformin on [kinesins, tubulins, histones, auroras and polo-like kinases] M-phase cell cycle genes in human breast cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12267

Aberrant mRNA translation in cancer pathogenesis: an old concept revisited comes finally of age.

21 January 2018

1 reference

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Bcl-2 inhibition of autophagy: a new route to cancer?

21 January 2018

1 reference

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Metformin therapy increases insulin-like growth factor binding protein-1 in hyperinsulinemic women with polycystic ovary syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12267

AMPK activators inhibit the proliferation of human melanomas bearing the activated MAPK pathway

21 January 2018

1 reference

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Therapeutic metformin/AMPK activation promotes the angiogenic phenotype in the ERalpha negative MDA-MB-435 breast cancer model

21 January 2018

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ATG12 conjugation to ATG3 regulates mitochondrial homeostasis and cell death

21 January 2018

1 reference

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Metformin attenuates ovarian cancer cell growth in an AMP-kinase dispensable manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12267

Overcoming intrinsic multidrug resistance in melanoma by blocking the mitochondrial respiratory chain of slow-cycling JARID1B(high) cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12267

Metabolic actions of metformin in the heart can occur by AMPK-independent mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12267

Deficiency of LKB1 in skeletal muscle prevents AMPK activation and glucose uptake during contraction

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12267

Rag proteins regulate amino-acid-induced mTORC1 signalling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12267

Growing roles for the mTOR pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12267

Prevention of pancreatic cancer induction in hamsters by metformin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12267

Relevance of the OCT1 transporter to the antineoplastic effect of biguanides

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12267

The LKB1-AMPK pathway: metabolism and growth control in tumour suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12267

The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12267

Effect of genetic variation in the organic cation transporter 1 (OCT1) on metformin action

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12267

Metformin and lactic acidosis: cause or coincidence? A review of case reports

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12267

Mimicry of a cellular low energy status blocks tumor cell anabolism and suppresses the malignant phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12267

Cell cycle-dependent induction of autophagy, mitophagy and reticulophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12267

Metformin inhibits melanoma development through autophagy and apoptosis mechanisms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12267

Regulation of insulin signalling by hyperinsulinaemia: role of IRS-1/2 serine phosphorylation and the mTOR/p70 S6K pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12267

Metformin induces apoptosis of pancreatic cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12267

On the Origin of Cancer Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12267

AMP-activated kinase (AMPK)-generated signals in malignant melanoma cell growth and survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12267

Autophagosome formation: core machinery and adaptations

21 January 2018

1 reference

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Phosphorylation of LKB1 at serine 428 by protein kinase C-zeta is required for metformin-enhanced activation of the AMP-activated protein kinase in endothelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12267

Targeting insulin-like growth factor pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12267

Phenformin enhances the therapeutic benefit of BRAF(V600E) inhibition in melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12267

Melanoma stem cells: the dark seed of melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12267

Metformin is an AMP kinase-dependent growth inhibitor for breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12267

Immunotherapy for malignant melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12267

Role of AMP-activated protein kinase in mechanism of metformin action

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12267