(Q38243161)

31 August 2017

title

Haematopoietic development and leukaemia in Down syndrome (English)

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31 August 2017

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Irene Roberts

1

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31 August 2017

Shai Izraeli

series ordinal

2

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31 August 2017

language of work or name

English

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publication date

22 August 2014

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British Journal of Haematology

31 August 2017

published in

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31 August 2017

volume

167

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31 August 2017

issue

5

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31 August 2017

page(s)

587-599

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Natural history of GATA1 mutations in Down syndrome

31 August 2017

cites work

1 reference

Classification of human chromosome 21 gene-expression variations in Down syndrome: impact on disease phenotypes

21 January 2018

1 reference

Perturbed hematopoiesis in the Tc1 mouse model of Down syndrome

21 January 2018

1 reference

Mutations of JAK2 in acute lymphoblastic leukaemias associated with Down's syndrome

21 January 2018

1 reference

Perturbation of fetal hematopoiesis in a mouse model of Down syndrome's transient myeloproliferative disorder

21 January 2018

1 reference

Identification of distinct molecular phenotypes in acute megakaryoblastic leukemia by gene expression profiling.

21 January 2018

1 reference

Acute lymphoblastic leukemia in children with Down syndrome: a retrospective analysis from the Ponte di Legno study group

21 January 2018

1 reference

Fetal liver hepatic progenitors are supportive stromal cells for hematopoietic stem cells

21 January 2018

1 reference

Trisomy 21 enhances human fetal erythro-megakaryocytic development

21 January 2018

1 reference

Trisomy 21-associated defects in human primitive hematopoiesis revealed through induced pluripotent stem cells

21 January 2018

1 reference

Altered expression of mitochondrial and extracellular matrix genes in the heart of human fetuses with chromosome 21 trisomy

21 January 2018

1 reference

The cerebellar transcriptome during postnatal development of the Ts1Cje mouse, a segmental trisomy model for Down syndrome.

21 January 2018

1 reference

RUNX1 regulates phosphoinositide 3-kinase/AKT pathway: role in chemotherapy sensitivity in acute megakaryocytic leukemia.

21 January 2018

1 reference

RUNX1 and GATA-1 coexpression and cooperation in megakaryocytic differentiation

21 January 2018

1 reference

miR-99a/100~125b tricistrons regulate hematopoietic stem and progenitor cell homeostasis by shifting the balance between TGFβ and Wnt signaling

21 January 2018

1 reference

Cytogenetic features of acute lymphoblastic and myeloid leukemias in pediatric patients with Down syndrome: an iBFM-SG study

21 January 2018

1 reference

Natural history of transient myeloproliferative disorder clinically diagnosed in Down syndrome neonates: a report from the Children's Oncology Group Study A2971.

21 January 2018

1 reference

Constitutional aneuploidy and cancer predisposition

21 January 2018

1 reference

The role of parathyroid hormone and insulin-like growth factors in hematopoietic niches: physiology and pharmacology

21 January 2018

1 reference

Risk of death for children with down syndrome and sepsis

21 January 2018

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MicroRNA fingerprints during human megakaryocytopoiesis

21 January 2018

1 reference

The role of cytidine deaminase and GATA1 mutations in the increased cytosine arabinoside sensitivity of Down syndrome myeloblasts and leukemia cell lines

21 January 2018

1 reference

GATA1, cytidine deaminase, and the high cure rate of Down syndrome children with acute megakaryocytic leukemia.

21 January 2018

1 reference

Hsa-mir-125b-2 is highly expressed in childhood ETV6/RUNX1 (TEL/AML1) leukemias and confers survival advantage to growth inhibitory signals independent of p53

21 January 2018

1 reference

Massively parallel sequencing reveals the complex structure of an irradiated human chromosome on a mouse background in the Tc1 model of Down syndrome

21 January 2018

1 reference

Acquired mutations in GATA1 in neonates with Down's syndrome with transient myeloid disorder

21 January 2018

1 reference

Risks of leukaemia and solid tumours in individuals with Down's syndrome.

21 January 2018

1 reference

A pediatric approach to the WHO classification of myelodysplastic and myeloproliferative diseases.

21 January 2018

1 reference

Severe TMD/AMKL with GATA1 mutation in a stillborn fetus with Down syndrome

21 January 2018

1 reference

Prediction of chromosomal aneuploidy from gene expression data.

21 January 2018

1 reference

Down syndrome acute lymphoblastic leukemia, a highly heterogeneous disease in which aberrant expression of CRLF2 is associated with mutated JAK2: a report from the International BFM Study Group

21 January 2018

1 reference

GATA1 mutations in transient leukemia and acute megakaryoblastic leukemia of Down syndrome

21 January 2018

1 reference

An inherited mutation leading to production of only the short isoform of GATA-1 is associated with impaired erythropoiesis

21 January 2018

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Chromosome copy number and leukemia-lessons from Down's syndrome

21 January 2018

1 reference

How I treat ALL in Down's syndrome: pathobiology and management

21 January 2018

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Translating dosage compensation to trisomy 21

21 January 2018

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Thyroid dysfunction in Down's syndrome: relation to age and thyroid autoimmunity

21 January 2018

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Highly penetrant myeloproliferative disease in the Ts65Dn mouse model of Down syndrome

21 January 2018

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Treatment and prognostic impact of transient leukemia in neonates with Down syndrome

21 January 2018

1 reference

Developmental stage-specific interplay of GATA1 and IGF signaling in fetal megakaryopoiesis and leukemogenesis

21 January 2018

1 reference

miR-125b-2 is a potential oncomiR on human chromosome 21 in megakaryoblastic leukemia

21 January 2018

1 reference

The genetic architecture of Down syndrome phenotypes revealed by high-resolution analysis of human segmental trisomies

21 January 2018

1 reference

Intrinsic defect of the immune system in children with Down syndrome: a review.

21 January 2018

1 reference

Triplication of a 21q22 region contributes to B cell transformation through HMGN1 overexpression and loss of histone H3 Lys27 trimethylation

21 January 2018

1 reference

Domains of genome-wide gene expression dysregulation in Down's syndrome.

21 January 2018

1 reference

Lack of age-associated LFA-1 up-regulation and impaired ICAM-1 binding in lymphocytes from patients with Down syndrome

21 January 2018

1 reference

Gene expression profiling in the adult Down syndrome brain.

21 January 2018

1 reference

Altered hematopoiesis in trisomy 21 as revealed through in vitro differentiation of isogenic human pluripotent cells

21 January 2018

1 reference

Insights into the manifestations, outcomes, and mechanisms of leukemogenesis in Down syndrome

21 January 2018

1 reference

Increased dosage of the chromosome 21 ortholog Dyrk1a promotes megakaryoblastic leukemia in a murine model of Down syndrome.

21 January 2018

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Development of acute megakaryoblastic leukemia in Down syndrome is associated with sequential epigenetic changes

21 January 2018

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GATA1s induces hyperproliferation of eosinophil precursors in Down syndrome transient leukemia

21 January 2018

1 reference

A prospective study of the natural history of transient leukemia (TL) in neonates with Down syndrome (DS): Children's Oncology Group (COG) study POG-9481.

21 January 2018

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Hematological abnormalities in adult patients with Down's syndrome

21 January 2018

1 reference

Rearrangement of CRLF2 in B-progenitor- and Down syndrome-associated acute lymphoblastic leukemia

21 January 2018

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Down syndrome (trisomy 21) thymuses have a decreased proportion of cells expressing high levels of TCR alpha, beta and CD3. A possible mechanism for diminished T cell function in Down syndrome

21 January 2018

1 reference

Familial dyserythropoietic anaemia and thrombocytopenia due to an inherited mutation in GATA1

21 January 2018

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Exome sequencing identifies putative drivers of progression of transient myeloproliferative disorder to AMKL in infants with Down syndrome.

21 January 2018

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Mutational processes molding the genomes of 21 breast cancers

21 January 2018

1 reference

Prognostic features in acute megakaryoblastic leukemia in children without Down syndrome: a report from the AML02 multicenter trial and the Children's Oncology Group Study POG 9421.

21 January 2018

1 reference

Incidence and clinical implications of GATA1 mutations in newborns with Down syndrome

21 January 2018

1 reference

Natural gene-expression variation in Down syndrome modulates the outcome of gene-dosage imbalance

21 January 2018

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Mutations in exon 2 of GATA1 are early events in megakaryocytic malignancies associated with trisomy 21

21 January 2018

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GATA1-mutant clones are frequent and often unsuspected in babies with Down syndrome: identification of a population at risk of leukemia

21 January 2018

1 reference

Acute megakaryoblastic leukaemia (AMKL) and transient myeloproliferative disorder (TMD) in Down syndrome: a multi-step model of myeloid leukaemogenesis

21 January 2018

1 reference

Perturbation of fetal liver hematopoietic stem and progenitor cell development by trisomy 21

21 January 2018

1 reference

Deregulated expression of cytokine receptor gene, CRLF2, is involved in lymphoid transformation in B-cell precursor acute lymphoblastic leukemia.

21 January 2018

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ERG is a megakaryocytic oncogene.

21 January 2018

1 reference

Exome sequencing identifies GATA1 mutations resulting in Diamond-Blackfan anemia

21 January 2018

1 reference

Gain-of-function mutations in interleukin-7 receptor-α (IL7R) in childhood acute lymphoblastic leukemias

21 January 2018

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Clinical characteristics and outcome of refractory/relapsed myeloid leukemia in children with Down syndrome.

21 January 2018

1 reference

Interleukin 7 and thymic stromal lymphopoietin: from immunity to leukemia

21 January 2018

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Naturally occurring oncogenic GATA1 mutants with internal deletions in transient abnormal myelopoiesis in Down syndrome

21 January 2018

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Abnormalities in the myeloid progenitor compartment in Down syndrome fetal liver precede acquisition of GATA1 mutations

21 January 2018

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The 2008 revision of the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia: rationale and important changes

21 January 2018

1 reference

Down syndrome B-lymphocyte subpopulations, intrinsic defect or decreased T-lymphocyte help.

21 January 2018

1 reference

Acquired mutations in GATA1 in the megakaryoblastic leukemia of Down syndrome

21 January 2018

1 reference

Frequent mutations in the GATA-1 gene in the transient myeloproliferative disorder of Down syndrome

21 January 2018

1 reference

Physical association of the patient-specific GATA1 mutants with RUNX1 in acute megakaryoblastic leukemia accompanying Down syndrome

21 January 2018

1 reference

The landscape of somatic mutations in Down syndrome-related myeloid disorders.

21 January 2018

1 reference

GABP controls a critical transcription regulatory module that is essential for maintenance and differentiation of hematopoietic stem/progenitor cells.

21 January 2018

1 reference

Insulin-like growth factor 2 expressed in a novel fetal liver cell population is a growth factor for hematopoietic stem cells

21 January 2018

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Susceptibility to leukemia and resistance to solid tumors in Down syndrome.

21 January 2018

1 reference

Transient leukaemia--a benign form of leukaemia in newborn infants with trisomy 21.

21 January 2018

1 reference

Acute leukemias in children with Down syndrome

21 January 2018

1 reference

Hematological abnormalities during the first week of life among neonates with Down syndrome: data from a multihospital healthcare system

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1111/BJH.13096

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release_fquixrq63bau7mam27z2wj2vju

31 August 2017

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/fquixrq63bau7mam27z2wj2vju

mapped directly with Wikidata item

24 November 2022

based on heuristic

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