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Clinical trials in amyotrophic lateral sclerosis: why so many negative trials and how can trials be improved?
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Europe PubMed Central
PubMed publication ID
25316019
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25316019%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 February 2020
review article
1 reference
stated in
Europe PubMed Central
title
Clinical trials in amyotrophic lateral sclerosis: why so many negative trials and how can trials be improved?
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
25316019
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25316019%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 February 2020
main subject
amyotrophic lateral sclerosis
0 references
author
Vincenzo Silani
series ordinal
3
1 reference
stated in
Europe PubMed Central
PubMed publication ID
25316019
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25316019%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 February 2020
Hiroshi Mitsumoto
series ordinal
1
object named as
Hiroshi Mitsumoto
1 reference
stated in
Europe PubMed Central
PubMed publication ID
25316019
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25316019%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 February 2020
author name string
Benjamin R Brooks
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
25316019
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25316019%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 February 2020
publication date
1 November 2014
1 reference
stated in
Europe PubMed Central
PubMed publication ID
25316019
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25316019%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 February 2020
published in
Lancet Neurology
1 reference
stated in
Europe PubMed Central
PubMed publication ID
25316019
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25316019%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 February 2020
volume
13
1 reference
stated in
Europe PubMed Central
PubMed publication ID
25316019
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25316019%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 February 2020
issue
11
1 reference
stated in
Europe PubMed Central
PubMed publication ID
25316019
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25316019%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 February 2020
page(s)
1127-1138
1 reference
stated in
Europe PubMed Central
PubMed publication ID
25316019
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25316019%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 February 2020
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Decreased glutamate transport by the brain and spinal cord in amyotrophic lateral sclerosis
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7 January 2021
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Update on the glutamatergic neurotransmitter system and the role of excitotoxicity in amyotrophic lateral sclerosis
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7 January 2021
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7 January 2021
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AMPA receptor calcium permeability, GluR2 expression, and selective motoneuron vulnerability
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7 January 2021
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Critical review of gangliosides and thyrotropin-releasing hormone in peripheral neuromuscular diseases
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7 January 2021
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inferred from DOI database lookup
Neurotrophic factors and neuromuscular disease: I. General comments, the neurotrophin family, and neuropoietic cytokines
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970129-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Neuroinflammation in amyotrophic lateral sclerosis: role of glial activation in motor neuron disease
1 reference
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Crossref
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7 January 2021
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Autoimmunity and ALS.
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7 January 2021
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inferred from DOI database lookup
Oxidative stress in ALS: key role in motor neuron injury and therapeutic target
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Crossref
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7 January 2021
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Clinical perspective on oxidative stress in sporadic amyotrophic lateral sclerosis
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Crossref
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7 January 2021
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Lithium delays progression of amyotrophic lateral sclerosis
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Crossref
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7 January 2021
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Treatment with arimoclomol, a coinducer of heat shock proteins, delays disease progression in ALS mice
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Crossref
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7 January 2021
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Emerging drugs for amyotrophic lateral sclerosis
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Controversies and priorities in amyotrophic lateral sclerosis
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Crossref
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https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970129-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Trends in risks associated with new drug development: success rates for investigational drugs
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Crossref
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https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970129-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Efficacy and safety of xaliproden in amyotrophic lateral sclerosis: results of two phase III trials
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Crossref
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7 January 2021
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inferred from DOI database lookup
A clinical trial of creatine in ALS.
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Crossref
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https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970129-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Creatine monohydrate in ALS: effects on strength, fatigue, respiratory status and ALSFRS.
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Crossref
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https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970129-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
High dose vitamin E therapy in amyotrophic lateral sclerosis as add-on therapy to riluzole: results of a placebo-controlled double-blind study
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970129-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Trial of celecoxib in amyotrophic lateral sclerosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970129-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Pentoxifylline in ALS: a double-blind, randomized, multicenter, placebo-controlled trial
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970129-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Efficacy of minocycline in patients with amyotrophic lateral sclerosis: a phase III randomised trial.
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970129-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Brain and plasma riluzole pharmacokinetics: effect of minocycline combination
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Crossref
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7 January 2021
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inferred from DOI database lookup
Phase II/III randomized trial of TCH346 in patients with ALS
1 reference
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Subcutaneous IGF-1 is not beneficial in 2-year ALS trial
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Phase II trial of CoQ10 for ALS finds insufficient evidence to justify phase III.
1 reference
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Erythropoietin in amyotrophic lateral sclerosis: a pilot, randomized, double-blind, placebo-controlled study of safety and tolerability.
1 reference
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Glatiramer acetate has no impact on disease progression in ALS at 40 mg/day: a double- blind, randomized, multicentre, placebo-controlled trial
1 reference
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Crossref
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7 January 2021
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inferred from DOI database lookup
Glatiramer acetate immunization induces specific antibody and cytokine responses in ALS patients
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Safety and efficacy of lithium in combination with riluzole for treatment of amyotrophic lateral sclerosis: a randomised, double-blind, placebo-controlled trial
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Lithium carbonate in amyotrophic lateral sclerosis: lack of efficacy in a dose-finding trial
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970129-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phase II screening trial of lithium carbonate in amyotrophic lateral sclerosis: examining a more efficient trial design
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970129-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Lithium lacks effect on survival in amyotrophic lateral sclerosis: a phase IIb randomised sequential trial
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970129-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Lithium in patients with amyotrophic lateral sclerosis (LiCALS): a phase 3 multicentre, randomised, double-blind, placebo-controlled trial
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970129-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A phase II trial of talampanel in subjects with amyotrophic lateral sclerosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970129-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A randomized, double blind, placebo-controlled trial of pioglitazone in combination with riluzole in amyotrophic lateral sclerosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970129-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Design and initial results of a multi-phase randomized trial of ceftriaxone in amyotrophic lateral sclerosis
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970129-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Randomized double-blind placebo-controlled trial of acetyl-L-carnitine for ALS.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970129-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Dexpramipexole versus placebo for patients with amyotrophic lateral sclerosis (EMPOWER): a randomised, double-blind, phase 3 trial
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970129-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
A post hoc analysis of subgroup outcomes and creatinine in the phase III clinical trial (EMPOWER) of dexpramipexole in ALS
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970129-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
A phase II−III trial of olesoxime in subjects with amyotrophic lateral sclerosis
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970129-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Of mice and men: reconciling preclinical ALS mouse studies and human clinical trials
1 reference
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Current status of thyrotropin-releasing hormone therapy in amyotrophic lateral sclerosis. Committee on Health Care Issues, American Neurological Association
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970129-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Neuroprotective effects of creatine in a transgenic animal model of amyotrophic lateral sclerosis.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970129-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Lithium therapy in ALS
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970129-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Comments on Fornai et al. (PNAS/ Feb 2008)
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970129-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
No benefit from chronic lithium dosing in a sibling-matched, gender balanced, investigator-blinded trial using a standard mouse model of familial ALS
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970129-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Treatment with lithium carbonate does not improve disease progression in two different strains of SOD1 mutant mice
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970129-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Accelerated clinical discovery using self-reported patient data collected online and a patient-matching algorithm
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970129-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
The unregulated commercialization of stem cell treatments: a global perspective.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970129-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Olfactory ensheathing glia injections in Beijing: misleading patients with ALS.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970129-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
No benefits from experimental treatment with olfactory ensheathing cells in patients with ALS.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970129-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mesenchymal stem cell transplantation in amyotrophic lateral sclerosis: A Phase I clinical trial
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970129-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Intraspinal neural stem cell transplantation in amyotrophic lateral sclerosis: phase 1 trial outcomes.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970129-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Intraspinal stem cell transplantation in amyotrophic lateral sclerosis: a phase I safety trial, technical note, and lumbar safety outcomes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970129-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A two-stage design for a phase II clinical trial of coenzyme Q10 in ALS.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970129-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A pilot, double-blind, placebo-controlled trial of indinavir in patients with ALS.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970129-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Prognostic factors for survival in amyotrophic lateral sclerosis patients treated with riluzole
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970129-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Guidelines for preclinical animal research in ALS/MND: A consensus meeting
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970129-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Policy: NIH plans to enhance reproducibility
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970129-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Preventing familial amyotrophic lateral sclerosis: is a clinical trial feasible?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970129-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An antisense oligonucleotide against SOD1 delivered intrathecally for patients with SOD1 familial amyotrophic lateral sclerosis: a phase 1, randomised, first-in-man study
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970129-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The epidemiology and treatment of ALS: focus on the heterogeneity of the disease and critical appraisal of therapeutic trials
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970129-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Alteration of nutritional status at diagnosis is a prognostic factor for survival of amyotrophic lateral sclerosis patients
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970129-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Prognostic factors in ALS: A critical review
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970129-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Can Selection of Rapidly Progressing Patients Shorten Clinical Trials in Amyotrophic Lateral Sclerosis?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970129-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cognitive decline and reduced survival in C9orf72 expansion frontotemporal degeneration and amyotrophic lateral sclerosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970129-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Executive dysfunction is a negative prognostic indicator in patients with ALS without dementia.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970129-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Degenerating compartment and functioning compartment of motor neurons in ALS: possible process of motor neuron loss
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970129-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Predictors of delay in the diagnosis and clinical trial entry of amyotrophic lateral sclerosis patients: a population-based study
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970129-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Electrodiagnostic criteria for diagnosis of ALS.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970129-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Lower motor neuron involvement examined by quantitative electromyography in amyotrophic lateral sclerosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970129-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A controlled trial of riluzole in amyotrophic lateral sclerosis. ALS/Riluzole Study Group
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970129-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Statistics in medicine--reporting of subgroup analyses in clinical trials.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970129-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Commentary on ‘A novel, efficient, randomized selection trial comparing combinations of drug therapy for ALS’
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970129-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Current pharmacological management of amyotrophic [corrected] lateral sclerosis and a role for rational polypharmacy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970129-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A novel, efficient, randomized selection trial comparing combinations of drug therapy for ALS.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970129-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Combination versus single agent chemotherapy: A review of the basis for selection of drug treatment of cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970129-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A randomized sequential trial of creatine in amyotrophic lateral sclerosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970129-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Pivotal studies of orphan drugs approved for neurological diseases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970129-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A double-blind study of L-threonine in patients with spinal spasticity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970129-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Noninvasive ventilation in ALS: indications and effect on quality of life
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970129-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Treatment of pseudobulbar affect in ALS with dextromethorphan/quinidine: a randomized trial
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970129-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dextromethorphan Plus Ultra Low‐Dose Quinidine Reduces Pseudobulbar Affect
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970129-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
High-frequency chest wall oscillation in ALS: an exploratory randomized, controlled trial.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970129-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
RETRACTED: Etidronate for fracture prevention in amyotrophic lateral sclerosis: a randomized controlled trial
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970129-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A randomized controlled trial of resistance exercise in individuals with ALS.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970129-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Modafinil treatment of fatigue in patients with ALS: a placebo-controlled study
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970129-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Randomized double-blind study of botulinum toxin type B for sialorrhea in ALS patients
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970129-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Botulinum toxin A versus B in sialorrhea: A prospective, randomized, double-blind, crossover pilot study in patients with amyotrophic lateral sclerosis or Parkinson's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970129-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effects of aerobic exercise therapy and cognitive behavioural therapy on functioning and quality of life in amyotrophic lateral sclerosis: protocol of the FACTS-2-ALS trial
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970129-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A study to evaluate safety and tolerability of repeated doses of tirasemtiv in patients with amyotrophic lateral sclerosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970129-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
High-caloric food supplements in the treatment of amyotrophic lateral sclerosis: A prospective interventional study
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970129-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hypercaloric enteral nutrition in patients with amyotrophic lateral sclerosis: a randomised, double-blind, placebo-controlled phase 2 trial
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970129-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Practice parameter update: the care of the patient with amyotrophic lateral sclerosis: multidisciplinary care, symptom management, and cognitive/behavioral impairment (an evidence-based review): report of the Quality Standards Subcommittee of the Am
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970129-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Practice parameter update: the care of the patient with amyotrophic lateral sclerosis: drug, nutritional, and respiratory therapies (an evidence-based review): report of the Quality Standards Subcommittee of the American Academy of Neurology
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970129-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S1474-4422(14)70129-2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
25316019
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25316019%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 February 2020
PubMed publication ID
25316019
1 reference
stated in
Europe PubMed Central
PubMed publication ID
25316019
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25316019%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 February 2020
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