(Q38314317)

2 September 2017

Translation-dependent displacement of UPF1 from coding sequences causes its enrichment in 3' UTRs (English)

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2 September 2017

3

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2 September 2017

Andreas R Gruber

2

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Oliver Mühlemann

series ordinal

4

object named as

Oliver Mühlemann

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2 September 2017

David Zünd

1

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2 September 2017

7 July 2013

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Nature Structural & Molecular Biology

2 September 2017

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2 September 2017

20

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2 September 2017

8

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2 September 2017

936-943

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https://scigraph.springernature.com/pub.10.1038/nsmb.2635

2 September 2017

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cites work

The human RNA surveillance factor UPF1 is required for S phase progression and genome stability

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Human UPF1 interacts with TPP1 and telomerase and sustains telomere leading-strand replication

21 January 2018

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Mammalian Staufen1 recruits Upf1 to specific mRNA 3'UTRs so as to elicit mRNA decay

21 January 2018

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Regulated degradation of replication-dependent histone mRNAs requires both ATR and Upf1

21 January 2018

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NMD: a multifaceted response to premature translational termination

21 January 2018

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Nonsense-mediated mRNA decay in human cells: mechanistic insights, functions beyond quality control and the double-life of NMD factors

21 January 2018

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Aberrant growth and lethality of Arabidopsis deficient in nonsense-mediated RNA decay factors is caused by autoimmune-like response

21 January 2018

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Rent1, a trans-effector of nonsense-mediated mRNA decay, is essential for mammalian embryonic viability

21 January 2018

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Nonsense-mediated mRNA decay effectors are essential for zebrafish embryonic development and survival

21 January 2018

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Drosophila Upf1 and Upf2 loss of function inhibits cell growth and causes animal death in a Upf3-independent manner

21 January 2018

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Nonsense surveillance regulates expression of diverse classes of mammalian transcripts and mutes genomic noise

21 January 2018

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Identification of hundreds of novel UPF1 target transcripts by direct determination of whole transcriptome stability

21 January 2018

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The abundance of RNPS1, a protein component of the exon junction complex, can determine the variability in efficiency of the Nonsense Mediated Decay pathway

21 January 2018

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Autoregulation of the nonsense-mediated mRNA decay pathway in human cells

21 January 2018

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RNA helicases at work: binding and rearranging

21 January 2018

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Molecular mechanisms for the RNA-dependent ATPase activity of Upf1 and its regulation by Upf2

21 January 2018

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Structural and functional insights into the human Upf1 helicase core

21 January 2018

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Unusual bipartite mode of interaction between the nonsense-mediated decay factors, UPF1 and UPF2

21 January 2018

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Characterization of the biochemical properties of the human Upf1 gene product that is involved in nonsense-mediated mRNA decay

21 January 2018

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NMD factors UPF2 and UPF3 bridge UPF1 to the exon junction complex and stimulate its RNA helicase activity

21 January 2018

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The surveillance complex interacts with the translation release factors to enhance termination and degrade aberrant mRNAs

21 January 2018

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Tight intramolecular regulation of the human Upf1 helicase by its N- and C-terminal domains

21 January 2018

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Upf1 ATPase-dependent mRNP disassembly is required for completion of nonsense- mediated mRNA decay

21 January 2018

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Binding of a novel SMG-1-Upf1-eRF1-eRF3 complex (SURF) to the exon junction complex triggers Upf1 phosphorylation and nonsense-mediated mRNA decay

21 January 2018

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A competition between stimulators and antagonists of Upf complex recruitment governs human nonsense-mediated mRNA decay

21 January 2018

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Poly(A)-binding protein acts in translation termination via eukaryotic release factor 3 interaction and does not influence [PSI(+)] propagation

21 January 2018

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The eukaryotic polypeptide chain releasing factor (eRF3/GSPT) carrying the translation termination signal to the 3'-Poly(A) tail of mRNA. Direct association of erf3/GSPT with polyadenylate-binding protein

21 January 2018

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Interactions between UPF1, eRFs, PABP and the exon junction complex suggest an integrated model for mammalian NMD pathways

21 January 2018

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A faux 3'-UTR promotes aberrant termination and triggers nonsense-mediated mRNA decay

21 January 2018

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A conserved role for cytoplasmic poly(A)-binding protein 1 (PABPC1) in nonsense-mediated mRNA decay

21 January 2018

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Posttranscriptional gene regulation by spatial rearrangement of the 3' untranslated region

21 January 2018

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Proximity of the poly(A)-binding protein to a premature termination codon inhibits mammalian nonsense-mediated mRNA decay

21 January 2018

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The cryo-EM structure of the UPF-EJC complex shows UPF1 poised toward the RNA 3' end.

21 January 2018

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The nonsense-mediated mRNA decay SMG-1 kinase is regulated by large-scale conformational changes controlled by SMG-8.

21 January 2018

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The role of SMG-1 in nonsense-mediated mRNA decay.

21 January 2018

1 reference

SMG7 is a 14-3-3-like adaptor in the nonsense-mediated mRNA decay pathway

21 January 2018

1 reference

N- and C-terminal Upf1 phosphorylations create binding platforms for SMG-6 and SMG-5:SMG-7 during NMD

21 January 2018

1 reference

An unusual arrangement of two 14-3-3-like domains in the SMG5-SMG7 heterodimer is required for efficient nonsense-mediated mRNA decay

21 January 2018

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SMG6 promotes endonucleolytic cleavage of nonsense mRNA in human cells

21 January 2018

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SMG6 is the catalytic endonuclease that cleaves mRNAs containing nonsense codons in metazoan

21 January 2018

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Human proline-rich nuclear receptor coregulatory protein 2 mediates an interaction between mRNA surveillance machinery and decapping complex

21 January 2018

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SMG5-PNRC2 is functionally dominant compared with SMG5-SMG7 in mammalian nonsense-mediated mRNA decay

21 January 2018

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SMG7 acts as a molecular link between mRNA surveillance and mRNA decay

21 January 2018

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Upf1 senses 3'UTR length to potentiate mRNA decay

21 January 2018

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Rules that govern UPF1 binding to mRNA 3' UTRs

21 January 2018

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iCLIP reveals the function of hnRNP particles in splicing at individual nucleotide resolution

21 January 2018

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Analysis of CLIP and iCLIP methods for nucleotide-resolution studies of protein-RNA interactions

21 January 2018

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CLIPZ: a database and analysis environment for experimentally determined binding sites of RNA-binding proteins

21 January 2018

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RNA homeostasis governed by cell type-specific and branched feedback loops acting on NMD.

21 January 2018

1 reference

Staufen1 regulates diverse classes of mammalian transcripts

21 January 2018

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A screen for nuclear transcripts identifies two linked noncoding RNAs associated with SC35 splicing domains

21 January 2018

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Efficient downregulation of immunoglobulin mu mRNA with premature translation-termination codons requires the 5'-half of the VDJ exon

21 January 2018

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Inhibition of Translation in Eukaryotic Systems by Harringtonine

21 January 2018

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Evidence for a pioneer round of mRNA translation: mRNAs subject to nonsense-mediated decay in mammalian cells are bound by CBP80 and CBP20

21 January 2018

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Human Upf proteins target an mRNA for nonsense-mediated decay when bound downstream of a termination codon

21 January 2018

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Separable roles for rent1/hUpf1 in altered splicing and decay of nonsense transcripts

21 January 2018

1 reference

21 January 2018

The meaning of nonsense

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SMG-2 is a phosphorylated protein required for mRNA surveillance in Caenorhabditis elegans and related to Upf1p of yeast

21 January 2018

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Mapping and quantifying mammalian transcriptomes by RNA-Seq

21 January 2018

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Fast mapping of short sequences with mismatches, insertions and deletions using index structures

21 January 2018

1 reference

WebLogo: A Sequence Logo Generator

21 January 2018

1 reference

FindPeaks 3.1: a tool for identifying areas of enrichment from massively parallel short-read sequencing technology

21 January 2018

1 reference

21 January 2018

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Translation is required to remove Y14 from mRNAs in the cytoplasm

21 January 2018

1 reference

CLIP-seq of eIF4AIII reveals transcriptome-wide mapping of the human exon junction complex

31 March 2020

1 reference

31 March 2020

Identifiers

DOI

10.1038/NSMB.2635

1 reference

PubMed ID

23832275

Dimensions Publication ID

2 September 2017

0 references

1 reference

PubMed ID

23832275