(Q42152373)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22522823%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

title

The cryo-EM structure of the UPF-EJC complex shows UPF1 poised toward the RNA 3' end (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22522823%20AND%20SRC:MED&resulttype=core&format=json

cryogenic electron microscopy

29 January 2020

main subject

0 references

author

David Gil

5

1 reference

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29 January 2020

Oscar Llorca

9

1 reference

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29 January 2020

Roberto Melero

1

1 reference

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29 January 2020

7

Henning Urlaub

1 reference

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29 January 2020

author name string

Gretel Buchwald

2

1 reference

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29 January 2020

Raquel Castaño

3

1 reference

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29 January 2020

Monika Raabe

4

1 reference

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29 January 2020

Melisa Lázaro

6

1 reference

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29 January 2020

Elena Conti

8

1 reference

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29 January 2020

publication date

22 April 2012

1 reference

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Nature Structural & Molecular Biology

29 January 2020

published in

1 reference

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29 January 2020

volume

19

1 reference

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29 January 2020

page(s)

498-505, S1-2

1 reference

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29 January 2020

issue

5

1 reference

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https://scigraph.springernature.com/pub.10.1038/nsmb.2287

29 January 2020

exact match

0 references

cites work

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1 reference

The many pathways of RNA degradation

21 January 2018

1 reference

The nonsense-mediated decay RNA surveillance pathway

21 January 2018

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21 January 2018

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21 January 2018

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A competition between stimulators and antagonists of Upf complex recruitment governs human nonsense-mediated mRNA decay

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21 January 2018

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A faux 3'-UTR promotes aberrant termination and triggers nonsense-mediated mRNA decay

21 January 2018

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A conserved role for cytoplasmic poly(A)-binding protein 1 (PABPC1) in nonsense-mediated mRNA decay

21 January 2018

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The exon-exon junction complex provides a binding platform for factors involved in mRNA export and nonsense-mediated mRNA decay

21 January 2018

1 reference

The exon junction complex differentially marks spliced junctions

21 January 2018

1 reference

The surveillance complex interacts with the translation release factors to enhance termination and degrade aberrant mRNAs

21 January 2018

1 reference

Binding of a novel SMG-1-Upf1-eRF1-eRF3 complex (SURF) to the exon junction complex triggers Upf1 phosphorylation and nonsense-mediated mRNA decay

21 January 2018

1 reference

Interactions between UPF1, eRFs, PABP and the exon junction complex suggest an integrated model for mammalian NMD pathways

21 January 2018

1 reference

A mutated human homologue to yeast Upf1 protein has a dominant-negative effect on the decay of nonsense-containing mRNAs in mammalian cells

21 January 2018

1 reference

NMD factors UPF2 and UPF3 bridge UPF1 to the exon junction complex and stimulate its RNA helicase activity

21 January 2018

1 reference

Molecular mechanisms for the RNA-dependent ATPase activity of Upf1 and its regulation by Upf2

21 January 2018

1 reference

Y14 and hUpf3b form an NMD-activating complex

21 January 2018

1 reference

Insights into the recruitment of the NMD machinery from the crystal structure of a core EJC-UPF3b complex

21 January 2018

1 reference

Human SMG-1, a novel phosphatidylinositol 3-kinase-related protein kinase, associates with components of the mRNA surveillance complex and is involved in the regulation of nonsense-mediated mRNA decay

21 January 2018

1 reference

SMG-8 and SMG-9, two novel subunits of the SMG-1 complex, regulate remodeling of the mRNA surveillance complex during nonsense-mediated mRNA decay

21 January 2018

1 reference

The nonsense-mediated mRNA decay SMG-1 kinase is regulated by large-scale conformational changes controlled by SMG-8.

21 January 2018

1 reference

N- and C-terminal Upf1 phosphorylations create binding platforms for SMG-6 and SMG-5:SMG-7 during NMD

21 January 2018

1 reference

Upf1 phosphorylation triggers translational repression during nonsense-mediated mRNA decay

21 January 2018

1 reference

SMG7 is a 14-3-3-like adaptor in the nonsense-mediated mRNA decay pathway

21 January 2018

1 reference

Evidence for a pioneer round of mRNA translation: mRNAs subject to nonsense-mediated decay in mammalian cells are bound by CBP80 and CBP20

21 January 2018

1 reference

Upf1 senses 3'UTR length to potentiate mRNA decay

21 January 2018

1 reference

Exon-junction complex components specify distinct routes of nonsense-mediated mRNA decay with differential cofactor requirements

21 January 2018

1 reference

Upf1 ATPase-dependent mRNP disassembly is required for completion of nonsense- mediated mRNA decay

21 January 2018

1 reference

Structure of the exon junction core complex with a trapped DEAD-box ATPase bound to RNA

21 January 2018

1 reference

The crystal structure of the exon junction complex reveals how it maintains a stable grip on mRNA

21 January 2018

1 reference

The structural basis for the interaction between nonsense-mediated mRNA decay factors UPF2 and UPF3

21 January 2018

1 reference

Structural and functional insights into the human Upf1 helicase core

21 January 2018

1 reference

Unusual bipartite mode of interaction between the nonsense-mediated decay factors, UPF1 and UPF2

21 January 2018

1 reference

Identification and characterization of human orthologues to Saccharomyces cerevisiae Upf2 protein and Upf3 protein (Caenorhabditis elegans SMG-4)

21 January 2018

1 reference

The exon junction core complex is locked onto RNA by inhibition of eIF4AIII ATPase activity

21 January 2018

1 reference

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21 January 2018

1 reference

Three-dimensional reconstruction from a single-exposure, random conical tilt series applied to the 50S ribosomal subunit of Escherichia coli

21 January 2018

2 references

https://pubmed.ncbi.nlm.nih.gov/22522823

21 January 2018

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Merging molecular electron microscopy and mass spectrometry by carbon film-assisted endoproteinase digestion

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Structural insights into RNA processing by the human RISC-loading complex

21 January 2018

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21 January 2018

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Coupled 5′ Nucleotide Recognition and Processivity in Xrn1-Mediated mRNA Decay

21 January 2018

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Disassembly of exon junction complexes by PYM

21 January 2018

1 reference

Control of RNP motility and localization by a splicing-dependent structure in oskar mRNA.

21 January 2018

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Cooperative hydrogen bond interactions in the streptavidin-biotin system

21 January 2018

1 reference

Accurate determination of local defocus and specimen tilt in electron microscopy

21 January 2018

1 reference

Bsoft: image processing and molecular modeling for electron microscopy

21 January 2018

1 reference

3-D structures of macromolecules using single-particle analysis in EMAN.

21 January 2018

1 reference

Image processing for electron microscopy single-particle analysis using XMIPP.

21 January 2018

1 reference

EMAN2: an extensible image processing suite for electron microscopy

21 January 2018

1 reference

SPIDER image processing for single-particle reconstruction of biological macromolecules from electron micrographs

21 January 2018

1 reference

Visualizing density maps with UCSF Chimera

21 January 2018

1 reference

Protein structure prediction on the Web: a case study using the Phyre server

21 January 2018

1 reference

The three-dimensional arcitecture of the EJC core

21 January 2018

1 reference

ATP is a cofactor of the Upf1 protein that modulates its translation termination and RNA binding activities

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22522823

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NSMB.2287

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22522823%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

1 reference