(Q38330390)

2 September 2017

Autophagy deficiency in beta cells leads to compromised unfolded protein response and progression from obesity to diabetes in mice (English)

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2 September 2017

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M Komatsu

13

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author name string

W Quan

1

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2 September 2017

K Y Hur

2

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2 September 2017

Y Lim

3

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2 September 2017

S H Oh

4

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2 September 2017

J-C Lee

5

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2 September 2017

K H Kim

6

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2 September 2017

G H Kim

7

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2 September 2017

S-W Kim

8

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2 September 2017

H L Kim

9

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2 September 2017

M-K Lee

10

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2 September 2017

K-W Kim

11

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2 September 2017

J Kim

12

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2 September 2017

M-S Lee

14

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2 September 2017

11 November 2011

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2 September 2017

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2 September 2017

55

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2 September 2017

392-403

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2 September 2017

2

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https://scigraph.springernature.com/pub.10.1007/s00125-011-2350-y

2 September 2017

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cites work

Autophagy as a regulated pathway of cellular degradation

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2350-Y

Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00125-011-2350-Y

Autophagy requires endoplasmic reticulum targeting of the PI3-kinase complex via Atg14L.

21 January 2018

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The roles of intracellular protein-degradation pathways in neurodegeneration

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00125-011-2350-Y

ER stress (PERK/eIF2alpha phosphorylation) mediates the polyglutamine-induced LC3 conversion, an essential step for autophagy formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2350-Y

Autophagy is activated for cell survival after endoplasmic reticulum stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2350-Y

Endoplasmic reticulum stress triggers autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2350-Y

Control of mRNA translation preserves endoplasmic reticulum function in beta cells and maintains glucose homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2350-Y

Endoplasmic reticulum stress contributes to beta cell apoptosis in type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2350-Y

Loss of autophagy diminishes pancreatic beta cell mass and function with resultant hyperglycemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2350-Y

Autophagy in human type 2 diabetes pancreatic beta cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2350-Y

In vivo analysis of autophagy in response to nutrient starvation using transgenic mice expressing a fluorescent autophagosome marker

21 January 2018

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Translation attenuation through eIF2alpha phosphorylation prevents oxidative stress and maintains the differentiated state in beta cells

21 January 2018

1 reference

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Role of calcium in pancreatic islet cell death by IFN-gamma/TNF-alpha

21 January 2018

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Lysophosphatidylcholine as a death effector in the lipoapoptosis of hepatocytes

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00125-011-2350-Y

Generation of cell lines with tetracycline-regulated autophagy and a role for autophagy in controlling cell size.

21 January 2018

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The regulatory subunits of PI3K, p85alpha and p85beta, interact with XBP-1 and increase its nuclear translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2350-Y

A regulatory subunit of phosphoinositide 3-kinase increases the nuclear accumulation of X-box-binding protein-1 to modulate the unfolded protein response

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2350-Y

Real-time redox measurements during endoplasmic reticulum stress reveal interlinked protein folding functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2350-Y

Initiation and execution of lipotoxic ER stress in pancreatic beta-cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2350-Y

RIP-Cre revisited, evidence for impairments of pancreatic beta-cell function

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00125-011-2350-Y

Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00125-011-2350-Y

Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

21 January 2018

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Autophagy regulates lipid metabolism

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00125-011-2350-Y

The role of autophagy in cardiomyocytes in the basal state and in response to hemodynamic stress

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00125-011-2350-Y

Defective hepatic autophagy in obesity promotes ER stress and causes insulin resistance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2350-Y

A decrease in cellular energy status stimulates PERK-dependent eIF2alpha phosphorylation and regulates protein synthesis in pancreatic beta-cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2350-Y

NF-kappa B prevents beta cell death and autoimmune diabetes in NOD mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2350-Y

Autophagy is important in islet homeostasis and compensatory increase of beta cell mass in response to high-fat diet

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2350-Y

Ubiquitin fold modifier 1 (UFM1) and its target UFBP1 protect pancreatic beta cells from ER stress-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2350-Y

Autophagy suppresses tumorigenesis through elimination of p62

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2350-Y

Altered lipid content inhibits autophagic vesicular fusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2350-Y

LC3, a microtubule-associated protein1A/B light chain3, is involved in cytoplasmic lipid droplet formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2350-Y

Dissecting the dynamic turnover of GFP-LC3 in the autolysosome

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22075916

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Transactivation of the grp78 promoter by Ca2+ depletion. A comparative analysis with A23187 and the endoplasmic reticulum Ca(2+)-ATPase inhibitor thapsigargin

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22075916

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Apoptosis of pancreatic beta-cells detected in accelerated diabetes of NOD mice: no role of Fas-Fas ligand interaction in autoimmune diabetes

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22075916

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1007/S00125-011-2350-Y

1 reference

Dimensions Publication ID

2 September 2017

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1 reference