(Q38333998)

2 September 2017

title

Deregulated apoptosis signaling in core-binding factor leukemia differentiates clinically relevant, molecular marker-independent subgroups (English)

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2 September 2017

7

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2 September 2017

S C Lück

1

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2 September 2017

A C Russ

2

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2 September 2017

U Botzenhardt

3

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2 September 2017

P Paschka

4

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2 September 2017

R F Schlenk

5

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2 September 2017

H Döhner

6

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2 September 2017

K Döhner

8

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2 September 2017

L Bullinger

9

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2 September 2017

publication date

24 June 2011

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2 September 2017

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2 September 2017

volume

25

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2 September 2017

issue

11

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2 September 2017

page(s)

1728-1738

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https://scigraph.springernature.com/pub.10.1038/leu.2011.154

2 September 2017

exact match

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cites work

Core binding factor acute myeloid leukemia

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.154

Core binding factor and its role in normal hematopoietic development

21 January 2018

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Identification of genes that synergize with Cbfb-MYH11 in the pathogenesis of acute myeloid leukemia

21 January 2018

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Gene-expression profiling identifies distinct subclasses of core binding factor acute myeloid leukemia

21 January 2018

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https://api.crossref.org/works/10.1038%2FLEU.2011.154

Prognostic factors and outcome of core binding factor acute myeloid leukemia patients with t(8;21) differ from those of patients with inv(16): a Cancer and Leukemia Group B study

21 January 2018

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https://api.crossref.org/works/10.1038%2FLEU.2011.154

Individual patient data-based meta-analysis of patients aged 16 to 60 years with core binding factor acute myeloid leukemia: a survey of the German Acute Myeloid Leukemia Intergroup

21 January 2018

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https://api.crossref.org/works/10.1038%2FLEU.2011.154

KIT mutations confer a distinct gene expression signature in core binding factor leukaemia

21 January 2018

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https://api.crossref.org/works/10.1038%2FLEU.2011.154

Adverse prognostic significance of KIT mutations in adult acute myeloid leukemia with inv(16) and t(8;21): a Cancer and Leukemia Group B Study

21 January 2018

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https://api.crossref.org/works/10.1038%2FLEU.2011.154

Cell death: critical control points

21 January 2018

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https://api.crossref.org/works/10.1038%2FLEU.2011.154

21 January 2018

The Hallmarks of Cancer

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https://api.crossref.org/works/10.1038%2FLEU.2011.154

IAPs: from caspase inhibitors to modulators of NF-kappaB, inflammation and cancer

21 January 2018

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Inhibitor of apoptosis proteins in hematological malignancies

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https://api.crossref.org/works/10.1038%2FLEU.2011.154

IAP antagonists induce autoubiquitination of c-IAPs, NF-kappaB activation, and TNFalpha-dependent apoptosis

21 January 2018

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https://api.crossref.org/works/10.1038%2FLEU.2011.154

Bcl-2 inhibitors: small molecules with a big impact on cancer therapy

21 January 2018

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An inhibitor of Bcl-2 family proteins induces regression of solid tumours

21 January 2018

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https://api.crossref.org/works/10.1038%2FLEU.2011.154

Targeting the mitogen-activated protein kinase pathway: physiological feedback and drug response

21 January 2018

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https://api.crossref.org/works/10.1038%2FLEU.2011.154

PAK signaling in oncogenesis.

21 January 2018

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https://api.crossref.org/works/10.1038%2FLEU.2011.154

Cell cycle, CDKs and cancer: a changing paradigm

21 January 2018

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Cluster analysis and display of genome-wide expression patterns

21 January 2018

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https://api.crossref.org/works/10.1038%2FLEU.2011.154

Reversal of stathmin-mediated resistance to paclitaxel and vinblastine in human breast carcinoma cells

21 January 2018

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https://api.crossref.org/works/10.1038%2FLEU.2011.154

An allosteric kinase inhibitor binds the p21-activated kinase autoregulatory domain covalently.

21 January 2018

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https://api.crossref.org/works/10.1038%2FLEU.2011.154

Insight into tubulin regulation from a complex with colchicine and a stathmin-like domain.

21 January 2018

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https://api.crossref.org/works/10.1038%2FLEU.2011.154

Microtubule dynamics as a target in oncology

21 January 2018

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Autocrine TNFalpha signaling renders human cancer cells susceptible to Smac-mimetic-induced apoptosis

21 January 2018

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The Bcl-2 homology domain 3 mimetic ABT-737 targets the apoptotic machinery in acute lymphoblastic leukemia resulting in synergistic in vitro and in vivo interactions with established drugs

21 January 2018

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https://api.crossref.org/works/10.1038%2FLEU.2011.154

Mechanisms of apoptosis sensitivity and resistance to the BH3 mimetic ABT-737 in acute myeloid leukemia

21 January 2018

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https://api.crossref.org/works/10.1038%2FLEU.2011.154

Therapeutic efficacy of ABT-737, a selective inhibitor of BCL-2, in small cell lung cancer

21 January 2018

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Influence of Bcl-2 family members on the cellular response of small-cell lung cancer cell lines to ABT-737.

21 January 2018

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https://api.crossref.org/works/10.1038%2FLEU.2011.154

'Seed' analysis of off-target siRNAs reveals an essential role of Mcl-1 in resistance to the small-molecule Bcl-2/Bcl-XL inhibitor ABT-737.

21 January 2018

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https://api.crossref.org/works/10.1038%2FLEU.2011.154

Acquired resistance to ABT-737 in lymphoma cells that up-regulate MCL-1 and BFL-1.

21 January 2018

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https://api.crossref.org/works/10.1038%2FLEU.2011.154

Identification of expression signatures predictive of sensitivity to the Bcl-2 family member inhibitor ABT-263 in small cell lung carcinoma and leukemia/lymphoma cell lines

21 January 2018

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https://api.crossref.org/works/10.1038%2FLEU.2011.154

An open-label, multicenter, phase I/II study of single-agent AT-101 in men with castrate-resistant prostate cancer

21 January 2018

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https://api.crossref.org/works/10.1038%2FLEU.2011.154

Phase I study of obatoclax mesylate (GX15-070), a small molecule pan-Bcl-2 family antagonist, in patients with advanced chronic lymphocytic leukemia

21 January 2018

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https://api.crossref.org/works/10.1038%2FLEU.2011.154

Navitoclax, a targeted high-affinity inhibitor of BCL-2, in lymphoid malignancies: a phase 1 dose-escalation study of safety, pharmacokinetics, pharmacodynamics, and antitumour activity

21 January 2018

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https://api.crossref.org/works/10.1038%2FLEU.2011.154

cIAP1, cIAP2, and XIAP act cooperatively via nonredundant pathways to regulate genotoxic stress-induced nuclear factor-kappaB activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.154

IAPs contain an evolutionarily conserved ubiquitin-binding domain that regulates NF-kappaB as well as cell survival and oncogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.154

RIPK1 is not essential for TNFR1-induced activation of NF-kappaB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.154

cIAP1 and cIAP2 facilitate cancer cell survival by functioning as E3 ligases that promote RIP1 ubiquitination

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.154

cIAP1 and TAK1 protect cells from TNF-induced necrosis by preventing RIP1/RIP3-dependent reactive oxygen species production

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.154

IAP-targeted therapies for cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.154

Molecular characterization of acute myeloid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.154

inferred from DOI database lookup

7 January 2021

based on heuristic

The clinical spectrum of adult acute myeloid leukaemia associated with core binding factor translocations

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.154

inferred from DOI database lookup

7 January 2021

based on heuristic

Therapeutic targeting of the MEK/MAPK signal transduction module in acute myeloid leukemia

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.154

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/LEU.2011.154

1 reference

Dimensions Publication ID

2 September 2017

1015514892

0 references

1 reference