(Q38359658)

2 September 2017

title

RAG1-DNA binding in V(D)J recombination. Specificity and DNA-induced conformational changes revealed by fluorescence and CD spectroscopy (English)

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2 September 2017

Mihai Ciubotaru

1

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2 September 2017

Leon M Ptaszek

2

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2 September 2017

Gary A Baker

3

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2 September 2017

Sheila N Baker

4

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2 September 2017

Frank V Bright

5

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2 September 2017

David G Schatz

6

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2 September 2017

language of work or name

English

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publication date

17 December 2002

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Journal of Biological Chemistry

2 September 2017

published in

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2 September 2017

volume

278

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2 September 2017

issue

8

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2 September 2017

page(s)

5584-5596

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Somatic generation of antibody diversity

2 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209758200

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21 January 2018

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The RAG proteins and V(D)J recombination: complexes, ends, and transposition

21 January 2018

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The RAG proteins in V(D)J recombination: more than just a nuclease

21 January 2018

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RAG-1 and RAG-2, adjacent genes that synergistically activate V(D)J recombination

21 January 2018

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The V(D)J recombination activating gene, RAG-1.

21 January 2018

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V(D)J recombination: modulation of RAG1 and RAG2 cleavage activity on 12/23 substrates by whole cell extract and DNA-bending proteins

21 January 2018

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Stimulation of V(D)J cleavage by high mobility group proteins

21 January 2018

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Analysis of regions of RAG-2 important for V(D)J recombination

21 January 2018

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Definition of a core region of RAG-2 that is functional in V(D)J recombination

21 January 2018

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Expression and V(D)J recombination activity of mutated RAG-1 proteins

21 January 2018

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Dispensable sequence motifs in the RAG-1 and RAG-2 genes for plasmid V(D)J recombination

21 January 2018

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RAG1 mediates signal sequence recognition and recruitment of RAG2 in V(D)J recombination

21 January 2018

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Distinct roles of RAG1 and RAG2 in binding the V(D)J recombination signal sequences

21 January 2018

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A stable RAG1-RAG2-DNA complex that is active in V(D)J cleavage

21 January 2018

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RAG1 and RAG2 cooperate in specific binding to the recombination signal sequence in vitro

21 January 2018

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RAG-2 promotes heptamer occupancy by RAG-1 in the assembly of a V(D)J initiation complex

21 January 2018

1 reference

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Identification of basic residues in RAG2 critical for DNA binding by the RAG1-RAG2 complex

21 January 2018

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Footprint analysis of the RAG protein recombination signal sequence complex for V(D)J type recombination.

21 January 2018

1 reference

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V(D)J recombination signal recognition: distinct, overlapping DNA-protein contacts in complexes containing RAG1 with and without RAG2.

21 January 2018

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A dimer of the lymphoid protein RAG1 recognizes the recombination signal sequence and the complex stably incorporates the high mobility group protein HMG2.

21 January 2018

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A RAG1 and RAG2 tetramer complex is active in cleavage in V(D)J recombination

21 January 2018

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A RAG-1/RAG-2 tetramer supports 12/23-regulated synapsis, cleavage, and transposition of V(D)J recombination signals

21 January 2018

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Functional organization of single and paired V(D)J cleavage complexes

21 January 2018

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Assembly of the RAG1/RAG2 synaptic complex

21 January 2018

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A C-terminal region of RAG1 contacts the coding DNA during V(D)J recombination.

21 January 2018

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The DDE motif in RAG-1 is contributed in trans to a single active site that catalyzes the nicking and transesterification steps of V(D)J recombination

21 January 2018

1 reference

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Cell cycle regulation of V(D)J recombination-activating protein RAG-2.

21 January 2018

1 reference

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Identification of two catalytic residues in RAG1 that define a single active site within the RAG1/RAG2 protein complex.

21 January 2018

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Transposition mediated by RAG1 and RAG2 and its implications for the evolution of the immune system

21 January 2018

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DNA-induced conformational changes in bacteriophage 434 repressor

21 January 2018

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HU binding to DNA: evidence for multiple complex formation and DNA bending

21 January 2018

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21 January 2018

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Fluorescence quenching studies: analysis of nonlinear Stern-Volmer data

21 January 2018

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Escherichia coli integration host factor stabilizes bacteriophage Mu repressor interactions with operator DNA in vitro

21 January 2018

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Effects of fluorescent probe structure on the dynamics at cysteine-34 within bovine serum albumin: evidence for probe-dependent modulation of the cybotactic region

21 January 2018

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Yeast TATA binding protein interaction with DNA: fluorescence determination of oligomeric state, equilibrium binding, on-rate, and dissociation kinetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209758200

Determination of protein tertiary structure class from circular dichroism spectra

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209758200

RAG-1 and RAG-2-dependent assembly of functional complexes with V(D)J recombination substrates in solution

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209758200

rag-1 and rag-2 are components of a high-molecular-weight complex, and association of rag-2 with this complex is rag-1 dependent

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209758200

Cyclin A/CDK2 regulates V(D)J recombination by coordinating RAG-2 accumulation and DNA repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209758200

Regulation of V(D)J recombination activator protein RAG-2 by phosphorylation

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M209758200

Dimer-dimer interfaces of the lambda-repressor are different in liganded and free states

21 January 2018

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Oligomeric states of the HIV-1 integrase as measured by time-resolved fluorescence anisotropy

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M209758200

DNA binding induces dissociation of the multimeric form of HIV-1 integrase: a time-resolved fluorescence anisotropy study

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M209758200

Crystal structure of the RAG1 dimerization domain reveals multiple zinc-binding motifs including a novel zinc binuclear cluster

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209758200

The homeodomain region of Rag-1 reveals the parallel mechanisms of bacterial and V(D)J recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209758200

Identification of two topologically independent domains in RAG1 and their role in macromolecular interactions relevant to V(D)J recombination

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M209758200

Effects of ethanol volume percent on fluorescein-labeled spinach apo- and holocalmodulin

21 January 2018

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Segmental flexibility in an antibody molecule

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M209758200

Theoretical CD studies of polypeptide helices: examination of important electronic and geometric factors

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M209758200

1 reference

2 September 2017

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