(Q38366488)

2 September 2017

1 reference

title

Hypocretin (orexin) biology and the pathophysiology of narcolepsy with cataplexy (English)

1 reference

2 September 2017

0 references

1 reference

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25728441%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Roland Liblau

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25728441%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Anne Vassalli

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25728441%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

author name string

Ali Seifinejad

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25728441%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

publication date

16 February 2015

1 reference

2 September 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25728441%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

volume

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25728441%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25728441%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

page(s)

318-328

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25728441%20AND%20SRC:MED&resulttype=core&format=json

Distinct narcolepsy syndromes in Orexin receptor-2 and Orexin null mice: molecular genetic dissection of Non-REM and REM sleep regulatory processes

4 June 2020

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Genetic ablation of orexin neurons in mice results in narcolepsy, hypophagia, and obesity

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7 January 2021

Narcolepsy in orexin knockout mice: molecular genetics of sleep regulation

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7 January 2021

The sleep disorder canine narcolepsy is caused by a mutation in the hypocretin (orexin) receptor 2 gene

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7 January 2021

Hypocretin (orexin) deficiency in human narcolepsy.

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7 January 2021

Reduced number of hypocretin neurons in human narcolepsy

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7 January 2021

A mutation in a case of early onset narcolepsy and a generalized absence of hypocretin peptides in human narcoleptic brains

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7 January 2021

Polymorphisms in hypocretin/orexin pathway genes and narcolepsy

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7 January 2021

Polymorphisms in the vicinity of the hypocretin/orexin are not associated with human narcolepsy

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7 January 2021

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7 January 2021

The hypocretins: hypothalamus-specific peptides with neuroexcitatory activity

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7 January 2021

Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior

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7 January 2021

Clinical, polysomnographic and genome-wide association analyses of narcolepsy with cataplexy: a European Narcolepsy Network study

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7 January 2021

Hypocretin (orexin) regulation of sleep-to-wake transitions

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7 January 2021

The hypocretins/orexins: integrators of multiple physiological functions

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7 January 2021

Discharge of identified orexin/hypocretin neurons across the sleep-waking cycle.

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7 January 2021

Release of hypocretin (orexin) during waking and sleep states.

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7 January 2021

Behavioral correlates of activity in identified hypocretin/orexin neurons

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7 January 2021

Human hypocretin and melanin-concentrating hormone levels are linked to emotion and social interaction

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7 January 2021

Increased body-mass index in patients with narcolepsy.

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7 January 2021

Body mass index-independent metabolic alterations in narcolepsy with cataplexy.

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7 January 2021

Glucose tolerance in patients with narcolepsy.

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7 January 2021

The hypocretins and the reward function: what have we learned so far?

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7 January 2021

Highly specific role of hypocretin (orexin) neurons: differential activation as a function of diurnal phase, operant reinforcement versus operant avoidance and light level

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970218-2

7 January 2021

Hypothalamic orexin neurons regulate arousal according to energy balance in mice

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970218-2

7 January 2021

Orexin signaling mediates the antidepressant-like effect of calorie restriction

1 reference

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7 January 2021

Orexin neurons function in an efferent pathway of a food-entrainable circadian oscillator in eliciting food-anticipatory activity and wakefulness.

1 reference

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7 January 2021

A role for hypocretin (orexin) in male sexual behavior.

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7 January 2021

Hypocretin-1 dose-dependently modulates maternal behaviour in mice

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7 January 2021

A key role for orexin in panic anxiety.

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7 January 2021

Hcrtr1 and 2 signaling differentially regulates depression-like behaviors

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7 January 2021

Dopaminergic regulation of sleep and cataplexy in a murine model of narcolepsy.

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7 January 2021

Orexin neurons suppress narcolepsy via 2 distinct efferent pathways

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7 January 2021

GABAB agonism promotes sleep and reduces cataplexy in murine narcolepsy

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7 January 2021

Tuning arousal with optogenetic modulation of locus coeruleus neurons

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7 January 2021

Locus coeruleus neurons: cessation of activity during cataplexy

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7 January 2021

Cataplexy-active neurons in the hypothalamus: implications for the role of histamine in sleep and waking behavior

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7 January 2021

Electroencephalogram paroxysmal θ characterizes cataplexy in mice and children.

1 reference

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7 January 2021

Neuronal activity in narcolepsy: identification of cataplexy-related cells in the medial medulla

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7 January 2021

Role of the medial prefrontal cortex in cataplexy.

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7 January 2021

Genetic and familial aspects of narcolepsy

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7 January 2021

Age at onset of narcolepsy in two large populations of patients in France and Quebec.

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7 January 2021

HLA and narcolepsy in a German population

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7 January 2021

HLA antigens in Japanese patients with narcolepsy. All the patients were DR2 positive

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7 January 2021

DQB1 locus alone explains most of the risk and protection in narcolepsy with cataplexy in Europe

1 reference

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7 January 2021

Complex HLA-DR and -DQ interactions confer risk of narcolepsy-cataplexy in three ethnic groups

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7 January 2021

HLA-DQ beta gene contributes to susceptibility and resistance to insulin-dependent diabetes mellitus

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7 January 2021

Crystal structure of HLA-DQ0602 that protects against type 1 diabetes and confers strong susceptibility to narcolepsy

1 reference

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7 January 2021

HLA-DQB1*0602 homozygosity increases relative risk for narcolepsy but not disease severity in two ethnic groups. US Modafinil in Narcolepsy Multicenter Study Group

1 reference

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7 January 2021

Linkage of human narcolepsy with HLA association to chromosome 4p13-q21

1 reference

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7 January 2021

A narcolepsy susceptibility locus maps to a 5 Mb region of chromosome 21q.

1 reference

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7 January 2021

A missense mutation in myelin oligodendrocyte glycoprotein as a cause of familial narcolepsy with cataplexy

1 reference

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7 January 2021

Narcolepsy is a common phenotype in HSAN IE and ADCA-DN.

1 reference

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7 January 2021

A novel de novo exon 21 DNMT1 mutation causes cerebellar ataxia, deafness, and narcolepsy in a Brazilian patient

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970218-2

7 January 2021

Mutations in DNMT1 cause autosomal dominant cerebellar ataxia, deafness and narcolepsy

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970218-2

7 January 2021

Genome-wide association study identifies new HLA class II haplotypes strongly protective against narcolepsy

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7 January 2021

Variant between CPT1B and CHKB associated with susceptibility to narcolepsy

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7 January 2021

Narcolepsy is strongly associated with the T-cell receptor alpha locus

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970218-2

7 January 2021

Genome wide analysis of narcolepsy in China implicates novel immune loci and reveals changes in association prior to versus after the 2009 H1N1 influenza pandemic

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970218-2

7 January 2021

Detecting shared pathogenesis from the shared genetics of immune-related diseases

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7 January 2021

Common variants in P2RY11 are associated with narcolepsy

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7 January 2021

ImmunoChip study implicates antigen presentation to T cells in narcolepsy

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970218-2

7 January 2021

Successful management of cataplexy with intravenous immunoglobulins at narcolepsy onset

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7 January 2021

Elevated anti-streptococcal antibodies in patients with recent narcolepsy onset

1 reference

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7 January 2021

Increased risk of narcolepsy in children and adults after pandemic H1N1 vaccination in France.

1 reference

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7 January 2021

Decreased incidence of childhood narcolepsy 2 years after the 2009 H1N1 winter flu pandemic

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7 January 2021

Possible association between HLA-B7 and narcolepsy

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7 January 2021

Genetic markers in narcolepsy

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7 January 2021

Post-H1N1 narcolepsy-cataplexy

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7 January 2021

AS03 adjuvanted AH1N1 vaccine associated with an abrupt increase in the incidence of childhood narcolepsy in Finland

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7 January 2021

Increased childhood incidence of narcolepsy in western Sweden after H1N1 influenza vaccination

1 reference

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7 January 2021

The incidence of narcolepsy in Europe: before, during, and after the influenza A(H1N1)pdm09 pandemic and vaccination campaigns

1 reference

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7 January 2021

Studies of humoral immunity to preprohypocretin in human leukocyte antigen DQB1*0602-positive narcoleptic subjects with cataplexy.

1 reference

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7 January 2021

Detection of autoantibodies against hypocretin, hcrtrl, and hcrtr2 in narcolepsy: anti-Hcrt system antibody in narcolepsy.

1 reference

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7 January 2021

Anti-Tribbles homolog 2 autoantibodies in Japanese patients with narcolepsy

1 reference

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7 January 2021

Anti-Tribbles homolog 2 (TRIB2) autoantibodies in narcolepsy are associated with recent onset of cataplexy

1 reference

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7 January 2021

Elevated Tribbles homolog 2-specific antibody levels in narcolepsy patients

1 reference

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7 January 2021

Neurons as targets for T cells in the nervous system.

1 reference

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7 January 2021

HLA class I and genetic susceptibility to type 1 diabetes: results from the Type 1 Diabetes Genetics Consortium

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7 January 2021

Herpes simplex virus encephalitis is a trigger of brain autoimmunity.

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7 January 2021

A functional autoantibody in narcolepsy.

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7 January 2021

Passive transfer of narcolepsy: anti-TRIB2 autoantibody positive patient IgG causes hypothalamic orexin neuron loss and sleep attacks in mice

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7 January 2021

Genetics of gene expression in primary immune cells identifies cell type-specific master regulators and roles of HLA alleles

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7 January 2021

Innate immune activity conditions the effect of regulatory variants upon monocyte gene expression

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7 January 2021

MHC class II signaling in antigen-presenting cells

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7 January 2021

Intracellular MHC class II molecules promote TLR-triggered innate immune responses by maintaining activation of the kinase Btk

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7 January 2021

Genetic variants regulating immune cell levels in health and disease.

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7 January 2021

The pathogenesis of poliomyelitis: what we don't know

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7 January 2021

HPV16 E6 variants and HLA class II polymorphism among Chinese women with cervical cancer

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7 January 2021

JC polyomavirus infection is strongly controlled by human leucocyte antigen class II variants

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7 January 2021

Deconstructing the Peptide-MHC Specificity of T Cell Recognition

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7 January 2021

A/H1N1 antibodies and TRIB2 autoantibodies in narcolepsy patients diagnosed in conjunction with the Pandemrix vaccination campaign in Sweden 2009-2010.

1 reference

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7 January 2021

Adjuvant System AS03 containing α-tocopherol modulates innate immune response and leads to improved adaptive immunity.

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7 January 2021

The adjuvant component α-tocopherol triggers via modulation of Nrf2 the expression and turnover of hypocretin in vitro and its implication to the development of narcolepsy

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7 January 2021

Pandemic influenza A H1N1 vaccines and narcolepsy: vaccine safety surveillance in action.

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7 January 2021

Immunopathogenesis of paraneoplastic neurological syndromes associated with anti-Hu antibodies: A beneficial antitumor immune response going awry

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7 January 2021

Neuroprotective intervention by interferon-γ blockade prevents CD8+ T cell-mediated dendrite and synapse loss

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7 January 2021

Therapeutic translation of iPSCs for treating neurological disease

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7 January 2021

Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors

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7 January 2021

Induced pluripotent stem cells from a spinal muscular atrophy patient

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7 January 2021

Subregional specification of embryonic stem cell-derived ventral telencephalic tissues by timed and combinatory treatment with extrinsic signals.

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7 January 2021

Prospective isolation of cortical interneuron precursors from mouse embryonic stem cells

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7 January 2021

From pluripotency to forebrain patterning: an in vitro journey astride embryonic stem cells

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7 January 2021

Differentiation and transplantation of functional pancreatic beta cells generated from induced pluripotent stem cells derived from a type 1 diabetes mouse model.

1 reference

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7 January 2021

iPSC-derived neural precursors exert a neuroprotective role in immune-mediated demyelination via the secretion of LIF.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970218-2

7 January 2021

Modelling schizophrenia using human induced pluripotent stem cells

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970218-2

7 January 2021

10.1016/S1474-4422(14)70218-2

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25728441%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

1 reference