(Q38367673)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25739910%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

review article

1 reference

title

Accelerated ageing of the lung in COPD: new concepts (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25739910%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

author name string

Nicolas Mercado

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25739910%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

language of work or name

English

0 references

publication date

4 March 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25739910%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25739910%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

volume

70

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25739910%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

issue

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25739910%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

page(s)

482-489

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25739910%20AND%20SRC:MED&resulttype=core&format=json

COPD as a disease of accelerated lung aging

2 March 2020

cites work

1 reference

https://api.crossref.org/works/10.1136%2FTHORAXJNL-2014-206084

Free radical theory of aging: an update: increasing the functional life span

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FTHORAXJNL-2014-206084

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FTHORAXJNL-2014-206084

Taking a "good" look at free radicals in the aging process

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FTHORAXJNL-2014-206084

Senescent cells, tumor suppression, and organismal aging: good citizens, bad neighbors

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FTHORAXJNL-2014-206084

Inflamm-ageing and lifelong antigenic load as major determinants of ageing rate and longevity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FTHORAXJNL-2014-206084

Premature lung aging and cellular senescence in the pathogenesis of idiopathic pulmonary fibrosis and COPD/emphysema

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FTHORAXJNL-2014-206084

The aging lung and chronic obstructive pulmonary disease: similarity and difference

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FTHORAXJNL-2014-206084

The role of mitochondria in aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FTHORAXJNL-2014-206084

IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FTHORAXJNL-2014-206084

Caloric restriction improves efficiency and capacity of the mitochondrial electron transport chain in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FTHORAXJNL-2014-206084

Regulation of lifespan in Drosophila by modulation of genes in the TOR signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FTHORAXJNL-2014-206084

21 January 2018

The hallmarks of aging

1 reference

https://api.crossref.org/works/10.1136%2FTHORAXJNL-2014-206084

p53, ROS and senescence in the control of aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FTHORAXJNL-2014-206084

Targeting phosphoinositide-3-kinase-delta with theophylline reverses corticosteroid insensitivity in chronic obstructive pulmonary disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FTHORAXJNL-2014-206084

Vascular endothelial growth factor activates PI3K/Akt/forkhead signaling in endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FTHORAXJNL-2014-206084

TGF-β and Smad3 modulate PI3K/Akt signaling pathway in vascular smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FTHORAXJNL-2014-206084

mTOR is a key modulator of ageing and age-related disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FTHORAXJNL-2014-206084

Mitochondrial H2O2 regulates the angiogenic phenotype via PTEN oxidation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FTHORAXJNL-2014-206084

PTEN identified as important risk factor of chronic obstructive pulmonary disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FTHORAXJNL-2014-206084

Sirtuins in stress response: guardians of the genome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FTHORAXJNL-2014-206084

A protein deacetylase SIRT1 is a negative regulator of metalloproteinase-9.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FTHORAXJNL-2014-206084

Geroprotectors as a novel therapeutic strategy for COPD, an accelerating aging disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FTHORAXJNL-2014-206084

Autophagy induction by SIRT6 through attenuation of insulin-like growth factor signaling is involved in the regulation of human bronchial epithelial cell senescence.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FTHORAXJNL-2014-206084

Sirtuin 6 (SIRT6) rescues the decline of homologous recombination repair during replicative senescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FTHORAXJNL-2014-206084

A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FTHORAXJNL-2014-206084

Increased Rheb-TOR signaling enhances sensitivity of the whole organism to oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FTHORAXJNL-2014-206084

FOXO3 deficiency leads to increased susceptibility to cigarette smoke-induced inflammation, airspace enlargement, and chronic obstructive pulmonary disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FTHORAXJNL-2014-206084

SIRT1 protects against emphysema via FOXO3-mediated reduction of premature senescence in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FTHORAXJNL-2014-206084

Decreased histone deacetylase 2 impairs Nrf2 activation by oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FTHORAXJNL-2014-206084

Decline in NRF2-regulated antioxidants in chronic obstructive pulmonary disease lungs due to loss of its positive regulator, DJ-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FTHORAXJNL-2014-206084

mTOR signaling in growth control and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FTHORAXJNL-2014-206084

FOXO3A directs a protective autophagy program in haematopoietic stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FTHORAXJNL-2014-206084

DNA damage as a molecular link in the pathogenesis of COPD in smokers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FTHORAXJNL-2014-206084

Dysfunction of endothelial progenitor cells from smokers and chronic obstructive pulmonary disease patients due to increased DNA damage and senescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FTHORAXJNL-2014-206084

Autophagy fights disease through cellular self-digestion

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FTHORAXJNL-2014-206084

Connecting autophagy to senescence in pathophysiology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FTHORAXJNL-2014-206084

Autosis is a Na+,K+-ATPase-regulated form of cell death triggered by autophagy-inducing peptides, starvation, and hypoxia-ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FTHORAXJNL-2014-206084

Autophagy protein microtubule-associated protein 1 light chain-3B (LC3B) activates extrinsic apoptosis during cigarette smoke-induced emphysema

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FTHORAXJNL-2014-206084

Egr-1 regulates autophagy in cigarette smoke-induced chronic obstructive pulmonary disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FTHORAXJNL-2014-206084

Histone deacetylase 6-mediated selective autophagy regulates COPD-associated cilia dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FTHORAXJNL-2014-206084

Mitophagy-dependent necroptosis contributes to the pathogenesis of COPD

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FTHORAXJNL-2014-206084

Insufficient autophagy promotes bronchial epithelial cell senescence in chronic obstructive pulmonary disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FTHORAXJNL-2014-206084

Prolonged cigarette smoke exposure alters mitochondrial structure and function in airway epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FTHORAXJNL-2014-206084

Functional interaction between autophagy and ciliogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FTHORAXJNL-2014-206084

Insufficient autophagy in idiopathic pulmonary fibrosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FTHORAXJNL-2014-206084

Reserve autophagic capacity in alveolar epithelia provides a replicative niche for influenza A virus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FTHORAXJNL-2014-206084

Autophagy as a stress-response and quality-control mechanism: implications for cell injury and human disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FTHORAXJNL-2014-206084

Smoking exposure induces human lung endothelial cell adaptation to apoptotic stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FTHORAXJNL-2014-206084

Identification of an autophagy defect in smokers' alveolar macrophages.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FTHORAXJNL-2014-206084

Carbon monoxide confers protection in sepsis by enhancing beclin 1-dependent autophagy and phagocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FTHORAXJNL-2014-206084

Defective phagocytosis in airways disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FTHORAXJNL-2014-206084

Mechanistic links between aging and lung fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FTHORAXJNL-2014-206084

Mitochondrial localization and function of heme oxygenase-1 in cigarette smoke-induced cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FTHORAXJNL-2014-206084

Downregulation of lung mitochondrial prohibitin in COPD.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FTHORAXJNL-2014-206084

Prohibitin 1 modulates mitochondrial stress-related autophagy in human colonic epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FTHORAXJNL-2014-206084

Prohibitin-1 maintains the angiogenic capacity of endothelial cells by regulating mitochondrial function and senescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FTHORAXJNL-2014-206084

Targeting mitochondrial dysfunction in lung diseases: emphasis on mitophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FTHORAXJNL-2014-206084

Mitochondria and mitophagy: the yin and yang of cell death control

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FTHORAXJNL-2014-206084

Mitochondrial fragmentation in cigarette smoke-induced bronchial epithelial cell senescence.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FTHORAXJNL-2014-206084

Parkin protein deficiency exacerbates cardiac injury and reduces survival following myocardial infarction

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FTHORAXJNL-2014-206084

Loss of PINK1 function promotes mitophagy through effects on oxidative stress and mitochondrial fission

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FTHORAXJNL-2014-206084

Mitochondrial turnover in the heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FTHORAXJNL-2014-206084

Role of PINK1 binding to the TOM complex and alternate intracellular membranes in recruitment and activation of the E3 ligase Parkin

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FTHORAXJNL-2014-206084

Mitophagy is triggered by mild oxidative stress in a mitochondrial fission dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FTHORAXJNL-2014-206084

Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FTHORAXJNL-2014-206084

TNF-alpha impairs regulation of muscle oxidative phenotype: implications for cachexia?

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FTHORAXJNL-2014-206084

Mitochondrial dysfunction and oxidative stress activate inflammasomes: impact on the aging process and age-related diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FTHORAXJNL-2014-206084

Telomere length is a determinant of emphysema susceptibility.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FTHORAXJNL-2014-206084

Concise review: clinical prospects for treating chronic obstructive pulmonary disease with regenerative approaches

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FTHORAXJNL-2014-206084

Metabolic requirements for the maintenance of self-renewing stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FTHORAXJNL-2014-206084

Type 2 alveolar cells are stem cells in adult lung.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FTHORAXJNL-2014-206084

Alveolar progenitor and stem cells in lung development, renewal and cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FTHORAXJNL-2014-206084

Isolation of alveolar epithelial type II progenitor cells from adult human lungs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FTHORAXJNL-2014-206084

c-Kit is essential for alveolar maintenance and protection from emphysema-like disease in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FTHORAXJNL-2014-206084

Mechanisms of immunosenescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FTHORAXJNL-2014-206084

Aging of the Innate Immune System: An Update

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FTHORAXJNL-2014-206084

Senescence in chronic obstructive pulmonary disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FTHORAXJNL-2014-206084

T cell senescence and contraction of T cell repertoire diversity in patients with chronic obstructive pulmonary disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FTHORAXJNL-2014-206084

Innate immunity and chronic obstructive pulmonary disease: a mini-review

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FTHORAXJNL-2014-206084

The search for antiaging interventions: from elixirs to fasting regimens

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FTHORAXJNL-2014-206084

Reprogramming of COPD lung fibroblasts through formation of induced pluripotent stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FTHORAXJNL-2014-206084