(Q38400938)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26526984%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

title

Phase 1 study of galunisertib, a TGF-beta receptor I kinase inhibitor, in Japanese patients with advanced solid tumors (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26526984%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

1 reference

ChEBI release 2020-05-28

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26526984%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Ken Ogasawara

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26526984%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

author name string

Hiroshi Nokihara

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26526984%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Yasuhide Yamada

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26526984%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Noboru Yamamoto

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26526984%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Kuniko Sunami

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26526984%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Hirofumi Utsumi

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26526984%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Hiroya Asou

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26526984%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Osamu TakahashI

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26526984%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Ivelina Gueorguieva

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26526984%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Tomohide Tamura

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26526984%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

language of work or name

1 reference

3 November 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26526984%20AND%20SRC:MED&resulttype=core&format=json

Cancer Chemotherapy and Pharmacology

28 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26526984%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

volume

76

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26526984%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

issue

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26526984%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

page(s)

1143-1152

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26526984%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1007/s00280-015-2895-4

28 February 2020

exact match

0 references

cites work

TGFbeta signaling in growth control, cancer, and heritable disorders

1 reference

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Role of transforming growth factor beta in cancer

21 January 2018

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Targeting the TGFβ signalling pathway in disease

21 January 2018

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TGF-beta signal transduction

21 January 2018

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New class of transforming growth factors potentiated by epidermal growth factor: isolation from non-neoplastic tissues

21 January 2018

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Transforming growth factor type beta: rapid induction of fibrosis and angiogenesis in vivo and stimulation of collagen formation in vitro

21 January 2018

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TGF-beta and epithelial-to-mesenchymal transitions

21 January 2018

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TGF-β inhibition enhances chemotherapy action against triple-negative breast cancer

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00280-015-2895-4

Semi-mechanistic modelling of the tumour growth inhibitory effects of LY2157299, a new type I receptor TGF-beta kinase antagonist, in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-015-2895-4

Differential Inhibition of the TGF-β Signaling Pathway in HCC Cells Using the Small Molecule Inhibitor LY2157299 and the D10 Monoclonal Antibody against TGF-β Receptor Type II.

21 January 2018

1 reference

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Transforming growth factor-β as a therapeutic target in hepatocellular carcinoma

21 January 2018

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TGF-beta inhibitors for the treatment of cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-015-2895-4

Anti-tumor activity of the TGF-β receptor kinase inhibitor galunisertib (LY2157299 monohydrate) in patient-derived tumor xenografts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-015-2895-4

Transforming growth factor-beta signaling in cancer invasion and metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-015-2895-4

Synthesis and activity of new aryl- and heteroaryl-substituted pyrazole inhibitors of the transforming growth factor-beta type I receptor kinase domain

21 January 2018

1 reference

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Induction of heart valve lesions by small-molecule ALK5 inhibitors.

21 January 2018

1 reference

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Defining a therapeutic window for the novel TGF-β inhibitor LY2157299 monohydrate based on a pharmacokinetic/pharmacodynamic model

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-015-2895-4

Pharmacokinetic, pharmacodynamic and biomarker evaluation of transforming growth factor-β receptor I kinase inhibitor, galunisertib, in phase 1 study in patients with advanced cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-015-2895-4