(Q38423379)

3 September 2017

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title

The NAIP-NLRC4 inflammasome in innate immune detection of bacterial flagellin and type III secretion apparatus (English)

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3 September 2017

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Yue Zhao

1

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PubMed ID

25879286

3 September 2017

Feng Shao

series ordinal

2

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PubMed ID

25879286

3 September 2017

language of work or name

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1 May 2015

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3 September 2017

Immunological Reviews

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3 September 2017

265

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3 September 2017

1

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3 September 2017

85-102

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Complete atomic model of the bacterial flagellar filament by electron cryomicroscopy

3 September 2017

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Structure of the bacterial flagellar protofilament and implications for a switch for supercoiling

21 January 2018

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Coordinating assembly of a bacterial macromolecular machine

21 January 2018

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Functions of bacterial flagella

21 January 2018

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Roles for motility in bacterial-host interactions

21 January 2018

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The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5

21 January 2018

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21 January 2018

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In vitro induction of cecropin genes--an immune response in a Drosophila blood cell line

21 January 2018

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MAP kinase signalling cascade in Arabidopsis innate immunity.

21 January 2018

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Bacterial type III secretion systems: specialized nanomachines for protein delivery into target cells

21 January 2018

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Polarisation of type III translocation by Pseudomonas aeruginosa requires PcrG, PcrV and PopN

21 January 2018

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Subversion of trafficking, apoptosis, and innate immunity by type III secretion system effectors

21 January 2018

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Biochemistry and cell signaling taught by bacterial effectors

21 January 2018

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Intimin and the host cell--is it bound to end in Tir(s)?

21 January 2018

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Molecular pathogenesis of Shigella spp.: controlling host cell signaling, invasion, and death by type III secretion.

21 January 2018

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The Salmonella-containing vacuole: moving with the times

21 January 2018

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Yersinia YopJ acetylates and inhibits kinase activation by blocking phosphorylation

21 January 2018

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The phosphothreonine lyase activity of a bacterial type III effector family

21 January 2018

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Cysteine methylation disrupts ubiquitin-chain sensing in NF-κB activation

21 January 2018

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Pathogen blocks host death receptor signalling by arginine GlcNAcylation of death domains

21 January 2018

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21 January 2018

The plant immune system

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Approaching the asymptote? Evolution and revolution in immunology

21 January 2018

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Approaching the asymptote: 20 years later

21 January 2018

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21 January 2018

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Innate immune sensing and signaling of cytosolic nucleic acids

21 January 2018

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The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta

21 January 2018

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Non-canonical inflammasome activation targets caspase-11

21 January 2018

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The death domain superfamily in intracellular signaling of apoptosis and inflammation

21 January 2018

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The PYHIN protein family as mediators of host defenses.

21 January 2018

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Structures of the HIN Domain:DNA Complexes Reveal Ligand Binding and Activation Mechanisms of the AIM2 Inflammasome and IFI16 Receptor

21 January 2018

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HIN-200 proteins regulate caspase activation in response to foreign cytoplasmic DNA

21 January 2018

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Molecular Mechanism for p202-Mediated Specific Inhibition of AIM2 Inflammasome Activation

21 January 2018

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IFI16 acts as a nuclear pathogen sensor to induce the inflammasome in response to Kaposi Sarcoma-associated herpesvirus infection

21 January 2018

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Interaction between pyrin and the apoptotic speck protein (ASC) modulates ASC-induced apoptosis

21 January 2018

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Cryopyrin and pyrin activate caspase-1, but not NF-kappaB, via ASC oligomerization.

21 January 2018

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A candidate gene for familial Mediterranean fever

21 January 2018

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Ancient Missense Mutations in a New Member of the RoRet Gene Family Are Likely to Cause Familial Mediterranean Fever

21 January 2018

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Innate immune sensing of bacterial modifications of Rho GTPases by the Pyrin inflammasome

21 January 2018

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Immunological function of familial Mediterranean fever disease protein Pyrin

21 January 2018

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NOD-like receptors: role in innate immunity and inflammatory disease

21 January 2018

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Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3

21 January 2018

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Plant NBS-LRR proteins in pathogen sensing and host defense

21 January 2018

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NALPs: a novel protein family involved in inflammation

21 January 2018

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Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle-Wells syndrome

21 January 2018

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NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder

21 January 2018

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Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3

21 January 2018

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Cryopyrin activates the inflammasome in response to toxins and ATP

21 January 2018

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Gout-associated uric acid crystals activate the NALP3 inflammasome

21 January 2018

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Mechanisms and functions of inflammasomes

21 January 2018

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PYPAF7, a novel PYRIN-containing Apaf1-like protein that regulates activation of NF-kappa B and caspase-1-dependent cytokine processing

21 January 2018

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PYPAF1, a PYRIN-containing Apaf1-like protein that assembles with ASC and regulates activation of NF-kappa B

21 January 2018

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The pyrin domain: a possible member of the death domain-fold family implicated in apoptosis and inflammation

21 January 2018

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NLRP6 negatively regulates innate immunity and host defence against bacterial pathogens

21 January 2018

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NLRP12 suppresses colon inflammation and tumorigenesis through the negative regulation of noncanonical NF-κB signaling

21 January 2018

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Identification of Ipaf, a human caspase-1-activating protein related to Apaf-1

21 January 2018

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Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf

21 January 2018

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The Salmonella invasin SipB induces macrophage apoptosis by binding to caspase-1

21 January 2018

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Cytosolic recognition of flagellin by mouse macrophages restricts Legionella pneumophila infection

21 January 2018

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Flagellin-deficient Legionella mutants evade caspase-1- and Naip5-mediated macrophage immunity

21 January 2018

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The Legionella pneumophila replication vacuole: making a cosy niche inside host cells

21 January 2018

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Type IV secretion systems: versatility and diversity in function

21 January 2018

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Bacterial type IV secretion: conjugation systems adapted to deliver effector molecules to host cells

21 January 2018

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A C-terminal translocation signal required for Dot/Icm-dependent delivery of the Legionella RalF protein to host cells

21 January 2018

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Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1beta in salmonella-infected macrophages

21 January 2018

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Cytoplasmic flagellin activates caspase-1 and secretion of interleukin 1beta via Ipaf

21 January 2018

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Injection of flagellin into the host cell cytosol by Salmonella enterica serotype Typhimurium

21 January 2018

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Regulation of Legionella phagosome maturation and infection through flagellin and host Ipaf.

21 January 2018

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Critical role for Ipaf in Pseudomonas aeruginosa-induced caspase-1 activation

21 January 2018

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Immune recognition of Pseudomonas aeruginosa mediated by the IPAF/NLRC4 inflammasome.

21 January 2018

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Pseudomonas aeruginosa activates caspase 1 through Ipaf

21 January 2018

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Multiple Nod-like receptors activate caspase 1 during Listeria monocytogenes infection

21 January 2018

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Differential regulation of caspase-1 activation, pyroptosis, and autophagy via Ipaf and ASC in Shigella-infected macrophages

21 January 2018

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Innate immune detection of the type III secretion apparatus through the NLRC4 inflammasome

21 January 2018

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Critical function for Naip5 in inflammasome activation by a conserved carboxy-terminal domain of flagellin

21 January 2018

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The inner rod protein controls substrate switching and needle length in a Salmonella type III secretion system

21 January 2018

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Innate immune recognition of bacterial ligands by NAIPs determines inflammasome specificity

21 January 2018

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The NLRC4 inflammasome receptors for bacterial flagellin and type III secretion apparatus.

21 January 2018

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Human NAIP and mouse NAIP1 recognize bacterial type III secretion needle protein for inflammasome activation

21 January 2018

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Naip5 affects host susceptibility to the intracellular pathogen Legionella pneumophila.

21 January 2018

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Birc1e is the gene within the Lgn1 locus associated with resistance to Legionella pneumophila.

21 January 2018

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The neuronal apoptosis inhibitory protein (Naip) is expressed in macrophages and is modulated after phagocytosis and during intracellular infection with Legionella pneumophila.

21 January 2018

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Toll-like receptor 5 recognizes a conserved site on flagellin required for protofilament formation and bacterial motility

21 January 2018

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Differential requirements for NAIP5 in activation of the NLRC4 inflammasome

21 January 2018

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A hemidominant Naip5 allele in mouse strain MOLF/Ei-derived macrophages restricts Legionella pneumophila intracellular growth.

21 January 2018

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Protective antigen-binding domain of anthrax lethal factor mediates translocation of a heterologous protein fused to its amino- or carboxy-terminus

21 January 2018

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Cutting edge: Mouse NAIP1 detects the type III secretion system needle protein

21 January 2018

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ASC, a novel 22-kDa protein, aggregates during apoptosis of human promyelocytic leukemia HL-60 cells

21 January 2018

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The PYRIN-CARD protein ASC is an activating adaptor for caspase-1

21 January 2018

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The pyroptosome: a supramolecular assembly of ASC dimers mediating inflammatory cell death via caspase-1 activation

21 January 2018

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Asc and Ipaf Inflammasomes direct distinct pathways for caspase-1 activation in response to Legionella pneumophila

21 January 2018

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Differential requirement for Caspase-1 autoproteolysis in pathogen-induced cell death and cytokine processing

21 January 2018

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The CARD plays a critical role in ASC foci formation and inflammasome signalling

21 January 2018

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Unified polymerization mechanism for the assembly of ASC-dependent inflammasomes

21 January 2018

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Crystal structure of NLRC4 reveals its autoinhibition mechanism

21 January 2018

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Structure of the apoptotic protease-activating factor 1 bound to ADP

21 January 2018

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Phosphorylation of NLRC4 is critical for inflammasome activation

21 January 2018

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Shigella type III secretion protein MxiI is recognized by Naip2 to induce Nlrc4 inflammasome activation independently of Pkcδ.

21 January 2018

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Formation and structure of a NAIP5-NLRC4 inflammasome induced by direct interactions with conserved N- and C-terminal regions of flagellin.

21 January 2018

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Crystal structure of the Caenorhabditis elegans apoptosome reveals an octameric assembly of CED-4

21 January 2018

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Molecular basis for specific recognition of bacterial ligands by NAIP/NLRC4 inflammasomes

21 January 2018

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Inflammasome activation causes dual recruitment of NLRC4 and NLRP3 to the same macromolecular complex.

21 January 2018

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Caspase-1-induced pyroptosis is an innate immune effector mechanism against intracellular bacteria.

21 January 2018

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Cooperation between multiple microbial pattern recognition systems is important for host protection against the intracellular pathogen Legionella pneumophila

21 January 2018

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Birc1e/Naip5 rapidly antagonizes modulation of phagosome maturation by Legionella pneumophila

21 January 2018

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Redundant roles for inflammasome receptors NLRP3 and NLRC4 in host defense against Salmonella

21 January 2018

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Epithelium-intrinsic NAIP/NLRC4 inflammasome drives infected enterocyte expulsion to restrict Salmonella replication in the intestinal mucosa

21 January 2018

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Contribution of flagellin pattern recognition to intestinal inflammation during Salmonella enterica serotype typhimurium infection

21 January 2018

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The neutrophil NLRC4 inflammasome selectively promotes IL-1β maturation without pyroptosis during acute Salmonella challenge

21 January 2018

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Role of the caspase-1 inflammasome in Salmonella typhimurium pathogenesis

21 January 2018

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Caspase-1-mediated activation of interleukin-1beta (IL-1beta) and IL-18 contributes to innate immune defenses against Salmonella enterica serovar Typhimurium infection

21 January 2018

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NLRC4-driven production of IL-1β discriminates between pathogenic and commensal bacteria and promotes host intestinal defense

21 January 2018

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Lethal inflammasome activation by a multidrug-resistant pathobiont upon antibiotic disruption of the microbiota

21 January 2018

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Rapid induction of inflammatory lipid mediators by the inflammasome in vivo

21 January 2018

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Temperature-dependent regulation of Yersinia enterocolitica Class III flagellar genes

21 January 2018

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Mycobacterium tuberculosis prevents inflammasome activation

21 January 2018

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A Yersinia effector protein promotes virulence by preventing inflammasome recognition of the type III secretion system

21 January 2018

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Structural and functional similarity between the bacterial type III secretion system needle protein PrgI and the eukaryotic apoptosis Bcl-2 proteins

21 January 2018

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NB-LRR proteins: pairs, pieces, perception, partners, and pathways

21 January 2018

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Mutation of NLRC4 causes a syndrome of enterocolitis and autoinflammation

21 January 2018

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An activating NLRC4 inflammasome mutation causes autoinflammation with recurrent macrophage activation syndrome

21 January 2018

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De novo CIAS1 mutations, cytokine activation, and evidence for genetic heterogeneity in patients with neonatal-onset multisystem inflammatory disease (NOMID): a new member of the expanding family of pyrin-associated autoinflammatory diseases

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1111/IMR.12293

1 reference

3 September 2017

1 reference

PubMed ID

25879286