(Q38475671)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21448187%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

title

New non-quinone geldanamycin analogs from genetically engineered Streptomyces hygroscopicus (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21448187%20AND%20SRC:MED&resulttype=core&format=json

Streptomyces hygroscopicus

26 January 2020

main subject

1 reference

1 reference

(13,17,20-Trihydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-3-oxo-2-azabicyclo[16.3.1]docosa-1(21),4,10,14,18(22),19-hexaen-9-yl) carbamate

1 reference

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21448187%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

8

Bang Yeon Hwang

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21448187%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

author name string

Cheng-Zhu Wu

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21448187%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

An Na Moon

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21448187%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

Jae-Hyuk Jang

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21448187%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

Dongho Lee

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21448187%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

Sun-Young Kang

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21448187%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

Joon-Tae Park

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21448187%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

Jong Seog Ahn

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21448187%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

Young Ho Kim

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21448187%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

Hong-Sub Lee

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21448187%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

publication date

30 March 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21448187%20AND%20SRC:MED&resulttype=core&format=json

full work available at URL

26 January 2020

https://www.nature.com/articles/ja201124.pdf

1 reference

19 March 2024

https://api.unpaywall.org/v2/10.1038/ja.2011.24?email=unpaywall_01@example.com

published in

The Journal of Antibiotics

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21448187%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

volume

64

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21448187%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

issue

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21448187%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

page(s)

461-463

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21448187%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

1 reference

19 March 2024

https://api.unpaywall.org/v2/10.1038/ja.2011.24?email=unpaywall_01@example.com

access restriction status

open access

1 reference

based on heuristic

inferred from online access status

exact match

https://scigraph.springernature.com/pub.10.1038/ja.2011.24

0 references

cites work

ATPase inhibitors of heat-shock protein 90, second season

1 reference

https://api.crossref.org/works/10.1038%2FJA.2011.24

HSP90 and the chaperoning of cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2011.24

Structure and functional relationships of Hsp90.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2011.24

Hsp90: a novel target for the disruption of multiple signaling cascades

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2011.24

A high-affinity conformation of Hsp90 confers tumour selectivity on Hsp90 inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2011.24

Cancer: the rules of attraction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2011.24

Inhibition of heat shock protein HSP90-pp60v-src heteroprotein complex formation by benzoquinone ansamycins: essential role for stress proteins in oncogenic transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2011.24

ATP binding and hydrolysis are essential to the function of the Hsp90 molecular chaperone in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2011.24

Preclinical pharmacologic evaluation of geldanamycin as an antitumor agent

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2011.24

Discovery and development of heat shock protein 90 inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2011.24

Heat-shock protein 90 inhibitors as novel cancer chemotherapeutics - an update

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2011.24

A phase II trial of 17-allylamino-17-demethoxygeldanamycin in patients with hormone-refractory metastatic prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2011.24

Dihydroquinone ansamycins: toward resolving the conflict between low in vitro affinity and high cellular potency of geldanamycin derivatives

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2011.24

Optimizing natural products by biosynthetic engineering: discovery of nonquinone Hsp90 inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2011.24

Rational biosynthetic engineering for optimization of geldanamycin analogues

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2011.24

Mutasynthesis of geldanamycin by the disruption of a gene producing starter unit: generation of structural diversity at the benzoquinone ring.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2011.24

Biosynthesis of the heat-shock protein 90 inhibitor geldanamycin: new insight into the formation of the benzoquinone moiety

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2011.24

Synthesis and anticancer activity of geldanamycin derivatives derived from biosynthetically generated metabolites

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2011.24

New tricyclic geldanamycin analogues from an engineered strain of Streptomyces hygroscopicus JCM4427

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2011.24

Reaction of geldanamycin and C17-substituted analogues with glutathione: product identifications and pharmacological implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2011.24

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/JA.2011.24

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21448187%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

26 January 2020

1005363767

0 references

1 reference