(Q38501146)

English

Green tea polyphenol epigallocatechin-3-gallate suppresses collagen production and proliferation in keloid fibroblasts via inhibition of the STAT3-signaling pathway

scientific article published on 08 May 2008

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scholarly article

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Europe PubMed Central

PubMed publication ID

3 September 2017

Green tea polyphenol epigallocatechin-3-gallate suppresses collagen production and proliferation in keloid fibroblasts via inhibition of the STAT3-signaling pathway (English)

1 reference

Europe PubMed Central

PubMed publication ID

3 September 2017

1 reference

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author name string

Gyuman Park

1

1 reference

Europe PubMed Central

PubMed publication ID

3 September 2017

Byung Sun Yoon

2

1 reference

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PubMed publication ID

3 September 2017

Jai-Hee Moon

3

1 reference

Europe PubMed Central

PubMed publication ID

3 September 2017

Bona Kim

4

1 reference

Europe PubMed Central

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3 September 2017

Eun Kyoung Jun

5

1 reference

Europe PubMed Central

PubMed publication ID

3 September 2017

Sejong Oh

6

1 reference

Europe PubMed Central

PubMed publication ID

3 September 2017

Hyunggee Kim

7

1 reference

Europe PubMed Central

PubMed publication ID

3 September 2017

Hea Joon Song

8

1 reference

Europe PubMed Central

PubMed publication ID

3 September 2017

Joo Young Noh

9

1 reference

Europe PubMed Central

PubMed publication ID

3 September 2017

Chilhwan Oh

10

1 reference

Europe PubMed Central

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3 September 2017

Seungkwon You

11

1 reference

Europe PubMed Central

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3 September 2017

language of work or name

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publication date

8 May 2008

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Europe PubMed Central

PubMed publication ID

3 September 2017

Journal of Investigative Dermatology

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Europe PubMed Central

PubMed publication ID

3 September 2017

128

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Europe PubMed Central

PubMed publication ID

3 September 2017

10

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Europe PubMed Central

PubMed publication ID

3 September 2017

2429-2441

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Europe PubMed Central

PubMed publication ID

3 September 2017

Epigallocathechin-3 gallate selectively inhibits the PDGF-BB-induced intracellular signaling transduction pathway in vascular smooth muscle cells and inhibits transformation of sis-transfected NIH 3T3 fibroblasts and human glioblastoma cells (A172).

1 reference

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Keloid pathogenesis and treatment

1 reference

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7 January 2021

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High glucose-induced replicative senescence: point of no return and effect of telomerase.

1 reference

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Epigallocatechin-3-gallate-induced stress signals in HT-29 human colon adenocarcinoma cells

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Stimulation of Type I Collagen Transcription in Human Skin Fibroblasts by TGF-β: Involvement of Smad 3

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Double-blinded, placebo-controlled trial of green tea extracts in the clinical and histologic appearance of photoaging skin.

1 reference

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STATs and gene regulation

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Inhibition of carcinogenesis by tea: the evidence from experimental studies

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Upregulation of transforming growth factor-beta1 and vascular endothelial growth factor in cultured keloid fibroblasts: relevance to angiogenic activity

1 reference

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Molecular pathway for (-)-epigallocatechin-3-gallate-induced cell cycle arrest and apoptosis of human prostate carcinoma cells

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Increased migration and metastatic potential of tumor cells expressing aquaporin water channels

1 reference

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7 January 2021

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(-)-Epigallocatechin-3-gallate, a polyphenolic compound from green tea, inhibits fibroblast adhesion and migration through multiple mechanisms

1 reference

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7 January 2021

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Safety studies on epigallocatechin gallate (EGCG) preparations. Part 2: dermal, acute and short-term toxicity studies

1 reference

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Detection and chemical identification of natural bio-antimutagens. A case of the green tea factor

1 reference

https://api.crossref.org/works/10.1038%2FJID.2008.103

7 January 2021

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Medical and surgical therapies for keloids

1 reference

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7 January 2021

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Upregulation of secretory connective tissue growth factor (CTGF) in keratinocyte-fibroblast coculture contributes to keloid pathogenesis

1 reference

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Safety of dietary supplements: chronotropic and inotropic effects on isolated rat atria

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Green tea polyphenols in the prevention of colon cancer

1 reference

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Activation of ERK and p38 kinase mediated keloid fibroblast apoptosis after flashlamp pulsed-dye laser treatment

1 reference

https://api.crossref.org/works/10.1038%2FJID.2008.103

7 January 2021

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Stat3 contributes to keloid pathogenesis via promoting collagen production, cell proliferation and migration.

1 reference

https://api.crossref.org/works/10.1038%2FJID.2008.103

7 January 2021

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Synchronous activation of ERK and phosphatidylinositol 3-kinase pathways is required for collagen and extracellular matrix production in keloids

1 reference

https://api.crossref.org/works/10.1038%2FJID.2008.103

7 January 2021

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Role of the Raf/MEK/ERK and the PI3K/Akt(PKB) pathways in fibroblast senescence

1 reference

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Abnormal balance between proliferation and apoptotic cell death in fibroblasts derived from keloid lesions

1 reference

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7 January 2021

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Keloids--clinical diagnosis, pathogenesis, and treatment options.

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7 January 2021

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Epigallocatechin-3-gallate decreases VEGF production in head and neck and breast carcinoma cells by inhibiting EGFR-related pathways of signal transduction.

1 reference

https://api.crossref.org/works/10.1038%2FJID.2008.103

7 January 2021

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Treatment of keloids and hypertrophic scars

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7 January 2021

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The effect of superpulsed carbon dioxide laser energy on keloid and normal dermal fibroblast secretion of growth factors: a serum-free study

1 reference

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7 January 2021

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Elevated polyamines lead to selective induction of apoptosis and inhibition of tumorigenesis by (-)-epigallocatechin-3-gallate (EGCG) in ODC/Ras transgenic mice

1 reference

https://api.crossref.org/works/10.1038%2FJID.2008.103

7 January 2021

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Smad3 signalling plays an important role in keloid pathogenesis via epithelial-mesenchymal interactions

1 reference

https://api.crossref.org/works/10.1038%2FJID.2008.103

7 January 2021

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Suppression of transforming growth factor beta/smad signaling in keloid-derived fibroblasts by quercetin: implications for the treatment of excessive scars.

1 reference

https://api.crossref.org/works/10.1038%2FJID.2008.103

7 January 2021

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Keloids - a frustrating hurdle in wound healing

1 reference

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Epigallocatechin-3-gallate inhibits epidermal growth factor receptor signaling pathway. Evidence for direct inhibition of ERK1/2 and AKT kinases.

1 reference

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Keloid fibroblast responsiveness to epidermal growth factor and activation of downstream intracellular signaling pathways

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Upregulation of the Wnt/beta-catenin pathway induced by transforming growth factor-beta in hypertrophic scars and keloids

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Molecular mechanisms underlying chemopreventive activities of anti-inflammatory phytochemicals: down-regulation of COX-2 and iNOS through suppression of NF-kappa B activation

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Platelet-derived growth factors-AA and -BB regulate collagen and collagenase gene expression differentially in human fibroblasts

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A single ascending dose study of epigallocatechin gallate in healthy volunteers

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The specific anti-cancer activity of green tea (-)-epigallocatechin-3-gallate (EGCG).

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Phosphorylation regulates Myc expression via prolonged activation of the mitogen-activated protein kinase pathway.

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Dexamethasone induction of keloid regression through effective suppression of VEGF expression and keloid fibroblast proliferation

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Increased vascular endothelial growth factor may account for elevated level of plasminogen activator inhibitor-1 via activating ERK1/2 in keloid fibroblasts

1 reference

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P38 MAP kinase mediates transforming growth factor-beta2 transcription in human keloid fibroblasts.

1 reference

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Cellular characteristics of primary and immortal canine embryonic fibroblast cells

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Crosstalk of hypoxia-mediated signaling pathways in upregulating plasminogen activator inhibitor-1 expression in keloid fibroblasts

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(-)-Epigallocatechin-3-gallate inhibits growth of gastric cancer by reducing VEGF production and angiogenesis

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Identifiers

10.1038/JID.2008.103

1 reference

Europe PubMed Central

PubMed publication ID

3 September 2017

Dimensions Publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

3 September 2017

ResearchGate publication ID

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