(Q40602773)

English

Epigallocatechin-3-gallate inhibits epidermal growth factor receptor signaling pathway. Evidence for direct inhibition of ERK1/2 and AKT kinases.

scientific article published on 29 December 2003

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scholarly article

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Europe PubMed Central

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17 November 2019

Epigallocatechin-3-gallate inhibits epidermal growth factor receptor signaling pathway. Evidence for direct inhibition of ERK1/2 and AKT kinases (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14701854%20AND%20SRC:MED&resulttype=core&format=json

17 November 2019

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17 November 2019

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Sivaprakasam Balasubramanian

2

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17 November 2019

Richard L Eckert

3

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17 November 2019

Ellen A Rorke

4

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17 November 2019

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29 December 2003

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17 November 2019

Journal of Biological Chemistry

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17 November 2019

279

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17 November 2019

12755-12762

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17 November 2019

13

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17 November 2019

The Hallmarks of Cancer

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Transcriptional regulation of the EGF receptor promoter by HPV16 and retinoic acid in human ectocervical epithelial cells

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Retinoids suppress epidermal growth factor-associated cell proliferation by inhibiting epidermal growth factor receptor-dependent ERK1/2 activation.

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Antimutagenic activity of tea towards 2-hydroxyamino-3-methylimidazo[4,5-f]quinoline: effect of tea concentration and brew time on electrophile scavenging.

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21 January 2018

Green tea polyphenol (-)-epigallocatechin 3-gallate inhibits MMP-2 secretion and MT1-MMP-driven migration in glioblastoma cells

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Ester bond-containing tea polyphenols potently inhibit proteasome activity in vitro and in vivo

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Growth inhibition of leukemic cells by (-)-epigallocatechin gallate, the main constituent of green tea.

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TGF-beta-mediated cell cycle arrest of HPV16-immortalized human ectocervical cells correlates with decreased E6/E7 mRNA and increased p53 and p21(WAF-1) expression.

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21 January 2018

Transforming growth factor beta regulation of epidermal growth factor receptor in ectocervical epithelial cells

1 reference

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21 January 2018

The protein kinase B/Akt signalling pathway in human malignancy

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21 January 2018

Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases

1 reference

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21 January 2018

p38 MAP kinases: beyond the stress response

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21 January 2018

Regulation of MAP kinase activity by peptide receptor signalling pathway: paradigms of multiplicity

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21 January 2018

Dual inhibition of focal adhesion kinase and epidermal growth factor receptor pathways cooperatively induces death receptor-mediated apoptosis in human breast cancer cells

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PIK3CA as an oncogene in cervical cancer

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Increase of the resistance of human cervical carcinoma cells to cisplatin by inhibition of the MEK to ERK signaling pathway partly via enhancement of anticancer drug-induced NF kappa B activation

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21 January 2018

Suppression of extracellular signals and cell proliferation through EGF receptor binding by (-)-epigallocatechin gallate in human A431 epidermoid carcinoma cells

1 reference

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21 January 2018

The EGF/ErbB receptor family and apoptosis

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21 January 2018

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

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21 January 2018

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

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21 January 2018

A phosphatidylinositol 3-kinase/Akt pathway promotes translocation of Mdm2 from the cytoplasm to the nucleus

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21 January 2018

The PTEN, Mdm2, p53 tumor suppressor-oncoprotein network

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21 January 2018

PKB/Akt mediates cell-cycle progression by phosphorylation of p27(Kip1) at threonine 157 and modulation of its cellular localization

1 reference

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21 January 2018

PKB/Akt phosphorylates p27, impairs nuclear import of p27 and opposes p27-mediated G1 arrest

1 reference

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21 January 2018

Cytoplasmic relocalization and inhibition of the cyclin-dependent kinase inhibitor p27(Kip1) by PKB/Akt-mediated phosphorylation in breast cancer

1 reference

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21 January 2018

The forkhead transcription factor FoxO regulates transcription of p27Kip1 and Bim in response to IL-2

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21 January 2018

Reversible G(1) arrest induced by inhibition of the epidermal growth factor receptor tyrosine kinase requires up-regulation of p27(KIP1) independent of MAPK activity

1 reference

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21 January 2018

Persistent ERK phosphorylation negatively regulates cAMP response element-binding protein (CREB) activity via recruitment of CREB-binding protein to pp90RSK.

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21 January 2018

Role and regulation of 90 kDa ribosomal S6 kinase (RSK) in signal transduction.

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21 January 2018

p38 Mitogen-activated protein kinases on the body surface--a function for p38 delta.

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21 January 2018

A regulatory role for p38 delta MAPK in keratinocyte differentiation. Evidence for p38 delta-ERK1/2 complex formation

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Identifiers

10.1074/JBC.M312333200

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14701854%20AND%20SRC:MED&resulttype=core&format=json

17 November 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14701854%20AND%20SRC:MED&resulttype=core&format=json

17 November 2019

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