(Q38516089)

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Identification of two distinct MYC breakpoint clusters and their association with various IGH breakpoint regions in the t(8;14) translocations in sporadic Burkitt-lymphoma.

scientific article published on 31 May 2007

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31 December 2019

Identification of two distinct MYC breakpoint clusters and their association with various IGH breakpoint regions in the t(8;14) translocations in sporadic Burkitt-lymphoma (English)

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31 December 2019

Burkitt lymphoma

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2

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31 December 2019

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Busch K

1

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31 December 2019

Fuchs U

3

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31 December 2019

Yeh RF

4

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31 December 2019

Harbott J

5

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31 December 2019

Klose I

6

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31 December 2019

Wiemels J

7

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31 December 2019

Novosel A

8

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31 December 2019

Reiter A

9

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31 December 2019

Borkhardt A

10

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31 December 2019

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31 May 2007

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31 December 2019

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31 December 2019

21

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31 December 2019

8

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31 December 2019

1739-1751

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31 December 2019

https://scigraph.springernature.com/pub.10.1038/sj.leu.2404753

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NF-kappa B p50-dependent in vivo footprints at Ig S gamma 3 DNA are correlated with mu-->gamma 3 switch recombination

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The RAG proteins and V(D)J recombination: complexes, ends, and transposition

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Translocation and rearrangements of the c-myc oncogene locus in human undifferentiated B-cell lymphomas

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V(D)J-mediated translocations in lymphoid neoplasms: a functional assessment of genomic instability by cryptic sites.

1 reference

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Mechanisms of chromosomal translocations in B cell lymphomas

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Frequent occurrence of deletions and duplications during somatic hypermutation: implications for oncogene translocations and heavy chain disease

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Genetic pathway to recurrent chromosome translocations in murine lymphoma involves V(D)J recombinase

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RAG proteins shepherd double-strand breaks to a specific pathway, suppressing error-prone repair, but RAG nicking initiates homologous recombination

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A non-B-DNA structure at the Bcl-2 major breakpoint region is cleaved by the RAG complex

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Both V(D)J coding ends but neither signal end can recombine at the bcl-2 major breakpoint region, and the rejoining is ligase IV dependent

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Double-strand break formation by the RAG complex at the bcl-2 major breakpoint region and at other non-B DNA structures in vitro

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Breakpoints of gross deletions coincide with non-B DNA conformations

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AID is required for c-myc/IgH chromosome translocations in vivo

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Reciprocal 8;14 translocation in EBV-negative B-cell acute lymphocytic leukemia with burkitt-type cells

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53BP1 links DNA damage-response pathways to immunoglobulin heavy chain class-switch recombination.

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Targeted transposition by the V(D)J recombinase

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Molecular mechanism of class switch recombination: linkage with somatic hypermutation

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Identifiers

10.1038/SJ.LEU.2404753

1 reference

Europe PubMed Central

PubMed publication ID

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31 December 2019

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1 reference

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PubMed publication ID

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31 December 2019

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