(Q38545726)

4 September 2017

1 reference

title

BAP1, PBRM1 and SETD2 in clear-cell renal cell carcinoma: molecular diagnostics and possible targets for personalized therapies (English)

1 reference

4 September 2017

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26166446%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

Matteo Santoni

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26166446%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

Matteo Giulietti

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26166446%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

F Massari

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26166446%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

Antonio Lopez-Beltran

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26166446%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

Giovanni Principato

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26166446%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

Stefano Cascinu

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26166446%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

10

Marina Scarpelli

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26166446%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

13

Rodolfo Montironi

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26166446%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

3

Marc R Matrana

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26166446%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

6

Giulia Occhipinti

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26166446%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

author name string

Suma Satti

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26166446%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

Liang Cheng

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26166446%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

publication date

11 July 2015

1 reference

Expert Review of Molecular Diagnostics: new diagnostic technologies are set to revolutionise healthcare

4 September 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26166446%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

volume

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26166446%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

page(s)

1201-1210

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26166446%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

issue

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26166446%20AND%20SRC:MED&resulttype=core&format=json

Bevacizumab plus interferon alfa-2a for treatment of metastatic renal cell carcinoma: a randomised, double-blind phase III trial

14 June 2020

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21 January 2018

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21 January 2018

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21 January 2018

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Efficacy of everolimus in advanced renal cell carcinoma: a double-blind, randomised, placebo-controlled phase III trial

21 January 2018

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Targeted therapies and complete responses in first line treatment of metastatic renal cell carcinoma. A meta-analysis of published trials.

21 January 2018

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Molecular genetics of clear-cell renal cell carcinoma

21 January 2018

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VHL loss actuates a HIF-independent senescence programme mediated by Rb and p400.

21 January 2018

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BAP1 loss defines a new class of renal cell carcinoma

21 January 2018

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Adverse outcomes in clear cell renal cell carcinoma with mutations of 3p21 epigenetic regulators BAP1 and SETD2: a report by MSKCC and the KIRC TCGA research network

21 January 2018

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Effects on survival of BAP1 and PBRM1 mutations in sporadic clear-cell renal-cell carcinoma: a retrospective analysis with independent validation

21 January 2018

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BRCA1-associated protein 1 interferes with BRCA1/BARD1 RING heterodimer activity

21 January 2018

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Activation of the E3 ligase function of the BRCA1/BARD1 complex by polyubiquitin chains

21 January 2018

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Bap1 is essential for kidney function and cooperates with Vhl in renal tumorigenesis

21 January 2018

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Frequent mutation of BAP1 in metastasizing uveal melanomas

21 January 2018

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Histone deacetylase inhibitors induce growth arrest and differentiation in uveal melanoma

21 January 2018

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BAP1 regulates cell cycle progression through E2F1 target genes and mediates transcriptional silencing via H2A monoubiquitination in uveal melanoma cells.

21 January 2018

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BAP1 has a survival role in cutaneous melanoma

21 January 2018

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The nuclear deubiquitinase BAP1 is commonly inactivated by somatic mutations and 3p21.1 losses in malignant pleural mesothelioma

21 January 2018

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Molecular pathways in renal cell carcinoma: recent advances in genetics and molecular biology

21 January 2018

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BAF180 is a critical regulator of p21 induction and a tumor suppressor mutated in breast cancer

21 January 2018

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Polybromo-associated BRG1-associated factor components BRD7 and BAF180 are critical regulators of p53 required for induction of replicative senescence

21 January 2018

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Requirement for PBAF in transcriptional repression and repair at DNA breaks in actively transcribed regions of chromatin

21 January 2018

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BAF180 promotes cohesion and prevents genome instability and aneuploidy

21 January 2018

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Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma

21 January 2018

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Convergent structural alterations define SWItch/Sucrose NonFermentable (SWI/SNF) chromatin remodeler as a central tumor suppressive complex in pancreatic cancer

21 January 2018

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The mRNA expression of SETD2 in human breast cancer: correlation with clinico-pathological parameters

21 January 2018

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The genetic basis of early T-cell precursor acute lymphoblastic leukaemia

21 January 2018

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Comprehensive molecular characterization of clear cell renal cell carcinoma

21 January 2018

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Variation in chromatin accessibility in human kidney cancer links H3K36 methyltransferase loss with widespread RNA processing defects

21 January 2018

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The histone mark H3K36me3 regulates human DNA mismatch repair through its interaction with MutSα

21 January 2018

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SETD2 is required for DNA double-strand break repair and activation of the p53-mediated checkpoint.

21 January 2018

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SETD2-dependent histone H3K36 trimethylation is required for homologous recombination repair and genome stability

21 January 2018

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Evolutionary constraint helps unmask a splicing regulatory region in BRCA1 exon 11

21 January 2018

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SpliceAid 2: a database of human splicing factors expression data and RNA target motifs

21 January 2018

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Clinical and pathologic impact of select chromatin-modulating tumor suppressors in clear cell renal cell carcinoma

21 January 2018

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Loss of PBRM1 expression is associated with renal cell carcinoma progression

21 January 2018

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Loss of PBRM1 and BAP1 expression is less common in non-clear cell renal cell carcinoma than in clear cell renal cell carcinoma

21 January 2018

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Spectrum of diverse genomic alterations define non-clear cell renal carcinoma subtypes

21 January 2018

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Genomic architecture and evolution of clear cell renal cell carcinomas defined by multiregion sequencing

21 January 2018

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Cooperation and antagonism among cancer genes: the renal cancer paradigm

21 January 2018

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Mutational landscape and significance across 12 major cancer types

21 January 2018

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Germline BAP1 mutations predispose to renal cell carcinomas

21 January 2018

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A novel germline mutation in BAP1 predisposes to familial clear-cell renal cell carcinoma.

21 January 2018

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Germline BAP1 mutation predisposes to uveal melanoma, lung adenocarcinoma, meningioma, and other cancers

21 January 2018

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Germline BAP1 mutations predispose to malignant mesothelioma

21 January 2018

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Germline BAP1 inactivation is preferentially associated with metastatic ocular melanoma and cutaneous-ocular melanoma families

21 January 2018

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Inference on germline BAP1 mutations and asbestos exposure from the analysis of familial and sporadic mesothelioma in a high-risk area

21 January 2018

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Aberrant promoter hypermethylation of PBRM1, BAP1, SETD2, KDM6A and other chromatin-modifying genes is absent or rare in clear cell RCC

21 January 2018

1 reference

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Loss of BAP1 protein expression is an independent marker of poor prognosis in patients with low-risk clear cell renal cell carcinoma

21 January 2018

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Radiogenomics of clear cell renal cell carcinoma: associations between CT imaging features and mutations

21 January 2018

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BAP1 is phosphorylated at serine 592 in S-phase following DNA damage

21 January 2018

1 reference

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Tumor suppressor and deubiquitinase BAP1 promotes DNA double-strand break repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.2015.1068122

Integrated molecular analysis of clear-cell renal cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.2015.1068122

Frequent mutations of genes encoding ubiquitin-mediated proteolysis pathway components in clear cell renal cell carcinoma

21 January 2018

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Prevalence of germlineBAP1mutation in a population-based sample of uveal melanoma cases

21 January 2018

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