(Q38580577)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26338715%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

title

Emerging trends in enzyme inhibition by multivalent nanoconstructs (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26338715%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26338715%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

Jean-Yves Winum

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26338715%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

Sébastien Ulrich

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26338715%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

Pascal Dumy

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26338715%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

author name string

Nasreddine Kanfar

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26338715%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

Renaud Zelli

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26338715%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

Alberto Marra

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26338715%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

publication date

1 October 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26338715%20AND%20SRC:MED&resulttype=core&format=json

Organic and Biomolecular Chemistry

23 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26338715%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

volume

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26338715%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

issue

39

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26338715%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

page(s)

9894-9906

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26338715%20AND%20SRC:MED&resulttype=core&format=json

Multivalency as a chemical organization and action principle

23 February 2020

cites work

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

The cluster glycoside effect

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

Multivalent scaffolds in glycoscience: an overview

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

Multivalent glycoconjugate syntheses and applications using aromatic scaffolds

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

Calixarene and calixresorcarene glycosides: their synthesis and biological applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

Synthetic non-peptide mimetics of alpha-helices

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

RAFT Nano-constructs: surfing to biological applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

Synthetic Peptide templates for molecular recognition: recent advances and applications.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

Glycoclusters on oligonucleotide and PNA scaffolds: synthesis and applications.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

Polymer therapeutics: concepts and applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

The dendritic effect illustrated with phosphorus dendrimers

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

Glycopeptide dendrimers as Pseudomonas aeruginosa biofilm inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

Biomedical applications of dendrimers: a tutorial

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

Click chemistry for drug development and diverse chemical-biology applications.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

Oxime ligation: a chemoselective click-type reaction for accessing multifunctional biomolecular constructs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

Recent applications of thiol-ene coupling as a click process for glycoconjugation

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

Thiol-ene click chemistry

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

Synthetic multivalent ligands as probes of signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

Tetravalent glycocyclopeptide with nanomolar affinity to wheat germ agglutinin

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

Size dependence of steric shielding and multivalency effects for globular binding inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

Multivalent iminosugars to modulate affinity and selectivity for glycosidases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

Topological effects and binding modes operating with multivalent iminosugar-based glycoclusters and mannosidases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

Glycosidase inhibition with fullerene iminosugar balls: a dramatic multivalent effect.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

Dimeric zanamivir conjugates with various linking groups are potent, long-lasting inhibitors of influenza neuraminidase including H5N1 avian influenza.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

Potent and long-acting dimeric inhibitors of influenza virus neuraminidase are effective at a once-weekly dosing regimen

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

Highly potent and long-acting trimeric and tetrameric inhibitors of influenza virus neuraminidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

Attaching zanamivir to a polymer markedly enhances its activity against drug-resistant strains of influenza a virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

Synthesis and anti-influenza evaluation of polyvalent sialidase inhibitors bearing 4-guanidino-Neu5Ac2en derivatives

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

Synthesis and anti-influenza evaluation of polyvalent sialidase inhibitors bearing 4-guanidino-Neu5Ac2en derivatives

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

Fluorescent Silica Nanoparticles with Multivalent Inhibitory Effects towards Carbonic Anhydrases

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

Dependence of avidity on linker length for a bivalent ligand-bivalent receptor model system

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

Exploring carbonic anhydrase inhibition with multimeric coumarins displayed on a fullerene scaffold.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

Bivalent inhibition of human beta-tryptase

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

Potent bivalent inhibition of human tryptase-beta by a synthetic inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

Bivalency as a principle for proteasome inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

Dimerized linear mimics of a natural cyclopeptide (TMC-95A) are potent noncovalent inhibitors of the eukaryotic 20S proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

Design and evaluation of novel bivalent thrombin inhibitors based on amidinophenylalanines

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

Double click reaction for the acquisition of a highly potent and selective mPTPB inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

Multivalency in the inhibition of oxidative protein folding by arsenic(III) species

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

Synthesis and 5-lipoxygenase inhibitory activity of new cinnamoyl and caffeoyl clusters.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

The multivalent effect in glycosidase inhibition: a new, rapidly emerging topic in glycoscience

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

Multivalent inhibitors for carbohydrate-processing enzymes: beyond the "lock-and-key" concept

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

The multivalent effect in glycosidase inhibition: probing the influence of valency, peripheral ligand structure, and topology with cyclodextrin-based iminosugar click clusters.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

Synthesis of the first examples of iminosugar clusters based on cyclopeptoid cores

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

Fullerene-sp2-iminosugar balls as multimodal ligands for lectins and glycosidases: a mechanistic hypothesis for the inhibitory multivalent effect.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

Enhancing the Receptor Affinity of the Sialic Acid-binding Domain of Vibrio cholerae Sialidase through Multivalency

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

Carbonic anhydrases: novel therapeutic applications for inhibitors and activators

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

Multiple binding modes of inhibitors to carbonic anhydrases: how to design specific drugs targeting 15 different isoforms?

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

Carbonic anhydrase inhibitors. Comparison of aliphatic sulfamate/bis-sulfamate adducts with isozymes II and IX as a platform for designing tight-binding, more isoform-selective inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

Development of potent carbonic anhydrase inhibitors incorporating both sulfonamide and sulfamide groups

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

Out of the active site binding pocket for carbonic anhydrase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

Probing the surface of human carbonic anhydrase for clues towards the design of isoform specific inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

The inhibition of liposaccharide heptosyltransferase WaaC with multivalent glycosylated fullerenes: a new mode of glycosyltransferase inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

Discovery of inhibitors of Shiga toxin type 2 by on-plate generation and screening of a focused compound library.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

Chemical biology. A small-molecule inhibitor of the aberrant transcription factor CBFβ-SMMHC delays leukemia in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

Supramolecular chemical biology; bioactive synthetic self-assemblies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

Combining supramolecular chemistry with biology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

Supramolecular Control of Enzyme Activity through Cucurbit[8]uril-Mediated Dimerization

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

Dynamic display of bioactivity through host-guest chemistry

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

Dynamic multivalency for carbohydrate-protein recognition through dynamic combinatorial libraries based on Fe(II)-bipyridine complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

Spatiotemporal control and superselectivity in supramolecular polymers using multivalency

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

PNA as a Biosupramolecular Tag for Programmable Assemblies and Reactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

DNA-scaffolded multivalent ligands to modulate cell function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

Programmable multivalent display of receptor ligands using peptide nucleic acid nanoscaffolds.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

Generating DNA synbodies from previously discovered peptides.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

Self-assembly at all scales

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

Multifunctional dendritic sialopolymersomes as potential antiviral agents: their lectin binding and drug release properties.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

Multiplexed supramolecular self-assembly for non-viral gene delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

Amphiphilic Dendrimers: Novel Self‐Assembling Vectors for Efficient Gene Delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

Effects of structural modification on gene transfection and self-assembling properties of amphiphilic dendrimers

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

Self-assembly, DNA complexation, and pH response of amphiphilic dendrimers for gene transfection

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

Synergistic effects in gene delivery-a structure-activity approach to the optimisation of hybrid dendritic-lipidic transfection agents.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

Degradable self-assembling dendrons for gene delivery: experimental and theoretical insights into the barriers to cellular uptake

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

Adaptive amphiphilic dendrimer-based nanoassemblies as robust and versatile siRNA delivery systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

Degradable hybrid materials based on cationic acylhydrazone dynamic covalent polymers promote DNA complexation through multivalent interactions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

20 years of DNA-encoded chemical libraries.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

Dual-display of small molecules enables the discovery of ligand pairs and facilitates affinity maturation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

Selection of Carbonic Anhydrase IX Inhibitors from One Million DNA-Encoded Compounds

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

Dynamic combinatorial/covalent chemistry: a tool to read, generate and modulate the bioactivity of compounds and compound mixtures

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

Evolution of dynamic combinatorial chemistry

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

Dynamic combinatorial libraries: from exploring molecular recognition to systems chemistry

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

Dynamic combinatorial chemistry: on the road to fulfilling the promise

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

Dynamic Combinatorial Chemistry

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

Dynamic covalent chemistry

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

Dynamic combinatorial chemistry: a tool to facilitate the identification of inhibitors for protein targets.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

Probing secondary interactions in biomolecular recognition by dynamic combinatorial chemistry

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

DNA-Encoded Dynamic Combinatorial Chemical Libraries.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

A multi-ligation strategy for the synthesis of heterofunctionalized glycosylated scaffolds.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

Orthogonality in organic, polymer, and supramolecular chemistry: from Merrifield to click chemistry

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

Molecular scaffolds using multiple orthogonal conjugations: applications in chemical biology and drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

Inhibition of herpes simplex virus type 1 infection by silver nanoparticles capped with mercaptoethane sulfonate

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

Inhibition of HSV-1 attachment, entry, and cell-to-cell spread by functionalized multivalent gold nanoparticles

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

Gold nanoparticles capped with sulfate-ended ligands as anti-HIV agents.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

Inhibition of HIV fusion with multivalent gold nanoparticles

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

Pseudosaccharide functionalized dendrimers as potent inhibitors of DC-SIGN dependent Ebola pseudotyped viral infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

Design of monodisperse and well-defined polypeptide-based polyvalent inhibitors of anthrax toxin

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

Self-Assembling Multivalency - Supramolecular Polymers Assembled from Monovalent Mannose-Labelled Discotic Molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

A bivalent small molecule-drug conjugate directed against carbonic anhydrase IX can elicit complete tumour regression in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

A Small-Molecule Drug Conjugate for the Treatment of Carbonic Anhydrase IX Expressing Tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

Dynamic Expression of DNA Complexation with Self-assembled Biomolecular Clusters

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

Hydrophobically Modified Dendrons: Developing Structure−Activity Relationships for DNA Binding and Gene Transfection

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

Access to Biomolecular Assemblies through One-Pot Triple Orthogonal Chemoselective Ligations

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

Carbonic Anhydrase Inhibitor Coated Gold Nanoparticles Selectively Inhibit the Tumor-Associated Isoform IX over the Cytosolic Isozymes I and II

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

Carbonic Anhydrase Activators: Gold Nanoparticles Coated with Derivatized Histamine, Histidine, and Carnosine Show Enhanced Activatory Effects on Several Mammalian Isoforms

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

Dual-site binding of bivalent 4-aminopyridine- and 4-aminoquinoline-based AChE inhibitors: contribution of the hydrophobic alkylene tether to monomer and dimer affinities

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB01405K

21 January 2018

Identifiers

DOI

10.1039/C5OB01405K

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26338715%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

1 reference