(Q44953389)

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Fullerene-sp2-iminosugar balls as multimodal ligands for lectins and glycosidases: a mechanistic hypothesis for the inhibitory multivalent effect.

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Europe PubMed Central

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28 February 2020

Fullerene-sp2-iminosugar balls as multimodal ligands for lectins and glycosidases: a mechanistic hypothesis for the inhibitory multivalent effect (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24150869%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

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Carmen Ortiz Mellet

4

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24150869%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

José Manuel García Fernández

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24150869%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

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Rocío Rísquez-Cuadro

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28 February 2020

Jean-François Nierengarten

3

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28 February 2020

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22 October 2013

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28 February 2020

Chemistry—A European Journal

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28 February 2020

19

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28 February 2020

49

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28 February 2020

16791-16803

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28 February 2020

Recent structural insights into the expanding world of carbohydrate-active enzymes

1 reference

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Complex genetic regulation of protein glycosylation

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Carbohydrate-binding modules: fine-tuning polysaccharide recognition

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1 reference

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21 January 2018

Structure and ligand binding of carbohydrate-binding module CsCBM6-3 reveals similarities with fucose-specific lectins and "galactose-binding" domains

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The C-Terminal Domain of the Arabinosyltransferase Mycobacterium tuberculosis EmbC Is a Lectin-Like Carbohydrate Binding Module

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History of lectins: from hemagglutinins to biological recognition molecules

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Conformational analyses of the reaction coordinate of glycosidases

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The cluster glycoside effect

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Design and creativity in synthesis of multivalent neoglycoconjugates

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Multivalent ligand presentation as a central concept to study intricate carbohydrate-protein interactions

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21 January 2018

Insights in the rational design of synthetic multivalent glycoconjugates as lectin ligands.

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Carbosilane glycodendrimers.

1 reference

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Multivalent glyco(cyclo)peptides.

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Cyclodextrin-based multivalent glycodisplays: covalent and supramolecular conjugates to assess carbohydrate-protein interactions.

1 reference

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Multivalency in heterogeneous glycoenvironments: hetero-glycoclusters, -glycopolymers and -glycoassemblies.

1 reference

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21 January 2018

Recent developments in design and synthesis of bicyclic azasugars, carbasugars and related molecules as glycosidase inhibitors

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21 January 2018

Developing inhibitors of glycan processing enzymes as tools for enabling glycobiology.

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Imino sugars and glycosyl hydrolases: historical context, current aspects, emerging trends

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21 January 2018

Synthetic multivalent ligands as probes of signal transduction

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21 January 2018

Recent progress and challenges in the discovery of new neuraminidase inhibitors

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21 January 2018

Recent advances in neuraminidase inhibitor development as anti-influenza drugs

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21 January 2018

Dimeric zanamivir conjugates with various linking groups are potent, long-lasting inhibitors of influenza neuraminidase including H5N1 avian influenza.

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21 January 2018

Highly potent and long-acting trimeric and tetrameric inhibitors of influenza virus neuraminidase

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21 January 2018

Multivalent iminosugars to modulate affinity and selectivity for glycosidases.

1 reference

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21 January 2018

Glycosidase inhibition with fullerene iminosugar balls: a dramatic multivalent effect.

1 reference

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21 January 2018

The multivalent effect in glycosidase inhibition: probing the influence of valency, peripheral ligand structure, and topology with cyclodextrin-based iminosugar click clusters.

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201303158

21 January 2018

Synthesis of dodecavalent fullerene-based glycoclusters and evaluation of their binding properties towards a bacterial lectin

1 reference

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21 January 2018

Multivalent protein-carbohydrate interactions: isothermal titration microcalorimetry studies

1 reference

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21 January 2018

The inhibition of liposaccharide heptosyltransferase WaaC with multivalent glycosylated fullerenes: a new mode of glycosyltransferase inhibition

1 reference

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21 January 2018

Synthesis of N-, S-, and C-glycoside castanospermine analogues with selective neutral alpha-glucosidase inhibitory activity as antitumour agents.

1 reference

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21 January 2018

sp2-Iminosugar O-, S-, and N-glycosides as conformational mimics of α-linked disaccharides; implications for glycosidase inhibition

1 reference

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A bicyclic 1-deoxygalactonojirimycin derivative as a novel pharmacological chaperone for GM1 gangliosidosis.

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Bicyclic derivatives of L-idonojirimycin as pharmacological chaperones for neuronopathic forms of Gaucher disease.

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Hepatocyte behavior on synthetic glycopolymer matrix: inhibitory effect of receptor-ligand binding on hepatocyte spreading.

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The functional valency of dodecamannosylated fullerenes with Escherichia coli FimH--towards novel bacterial antiadhesives.

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Crystal structures of isomaltase from Saccharomyces cerevisiae and in complex with its competitive inhibitor maltose

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1 reference

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Identifiers

10.1002/CHEM.201303158

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24150869%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24150869%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

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