(Q38587415)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26373263%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

title

Centrosome function and assembly in animal cells (English)

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24 February 2020

2

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24 February 2020

author name string

Paul T Conduit

series ordinal

1

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24 February 2020

Jordan W Raff

series ordinal

3

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24 February 2020

publication date

16 September 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26373263%20AND%20SRC:MED&resulttype=core&format=json

Nature Reviews Molecular Cell Biology

24 February 2020

published in

1 reference

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24 February 2020

volume

16

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24 February 2020

issue

10

1 reference

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24 February 2020

page(s)

611-624

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26373263%20AND%20SRC:MED&resulttype=core&format=json

The centrosome in cells and organisms

24 February 2020

cites work

1 reference

The centrosome and cellular organization

31 March 2020

1 reference

Exploring the evolutionary history of centrosomes

31 March 2020

1 reference

Centrosomes as signalling centres

31 March 2020

1 reference

Concerning the origin of malignant tumours by Theodor Boveri. Translated and annotated by Henry Harris

31 March 2020

1 reference

How do cilia organize signalling cascades?

31 March 2020

1 reference

The primary cilium: guardian of organ development and homeostasis

31 March 2020

1 reference

Recent advances in primary ciliary dyskinesia genetics.

31 March 2020

1 reference

Proteomic characterization of the human centrosome by protein correlation profiling

31 March 2020

1 reference

CentrosomeDB: a new generation of the centrosomal proteins database for Human and Drosophila melanogaster

31 March 2020

1 reference

The centrosome in vertebrates: more than a microtubule-organizing center

31 March 2020

1 reference

Centrosomes in cellular regulation

31 March 2020

1 reference

Centrosome duplication: of rules and licenses

31 March 2020

1 reference

The centrosome cycle: Centriole biogenesis, duplication and inherent asymmetries

31 March 2020

1 reference

Experiments concerning the cleavage stimulus in sand dollar eggs

31 March 2020

1 reference

Acentrosomal spindle assembly and chromosome segregation during oocyte meiosis

31 March 2020

1 reference

Microtubule nucleation and establishment of the mitotic spindle in vascular plant cells

31 March 2020

1 reference

Self-organization of microtubules into bipolar spindles around artificial chromosomes in Xenopus egg extracts

31 March 2020

1 reference

Morphogenetic properties of microtubules and mitotic spindle assembly

31 March 2020

1 reference

The mitotic spindle: a self-made machine

31 March 2020

1 reference

The mechanism of spindle assembly: functions of Ran and its target TPX2

31 March 2020

1 reference

Cooperative mechanisms of mitotic spindle formation

31 March 2020

1 reference

Augmin: a protein complex required for centrosome-independent microtubule generation within the spindle

31 March 2020

1 reference

New look inside the spindle: microtubule-dependent microtubule generation within the spindle

31 March 2020

1 reference

The augmin connection in the geometry of microtubule networks

31 March 2020

1 reference

HAUS, the 8-subunit human Augmin complex, regulates centrosome and spindle integrity

31 March 2020

1 reference

Self-organization of MTOCs replaces centrosome function during acentrosomal spindle assembly in live mouse oocytes

31 March 2020

1 reference

Dissecting the function and assembly of acentriolar microtubule organizing centers in Drosophila cells in vivo

31 March 2020

1 reference

Microtubule cytoskeleton remodeling by acentriolar microtubule-organizing centers at the entry and exit from mitosis in Drosophila somatic cells

31 March 2020

1 reference

Acentrosomal spindle organization renders cancer cells dependent on the kinesin HSET.

31 March 2020

1 reference

Synergy between multiple microtubule-generating pathways confers robustness to centrosome-driven mitotic spindle formation

31 March 2020

1 reference

Centrosome-independent mitotic spindle formation in vertebrates

31 March 2020

1 reference

Spindle assembly in Xenopus egg extracts: respective roles of centrosomes and microtubule self-organization

31 March 2020

1 reference

Loss of centrioles causes chromosomal instability in vertebrate somatic cells

31 March 2020

1 reference

31 March 2020

Flies without centrioles

1 reference

From stem cell to embryo without centrioles

31 March 2020

1 reference

Asterless is a centriolar protein required for centrosome function and embryo development in Drosophila

31 March 2020

1 reference

Centrosome loss or amplification does not dramatically perturb global gene expression in Drosophila

31 March 2020

1 reference

Centrosome loss in the evolution of planarians

31 March 2020

1 reference

Mechanisms of asymmetric cell division: flies and worms pave the way.

31 March 2020

1 reference

Asymmetric cell division: recent developments and their implications for tumour biology

31 March 2020

1 reference

Acentrosomal Drosophila epithelial cells exhibit abnormal cell division, leading to cell death and compensatory proliferation

31 March 2020

1 reference

Requirement of a centrosomal activity for cell cycle progression through G1 into S phase

31 March 2020

1 reference

Centrosomes enhance the fidelity of cytokinesis in vertebrates and are required for cell cycle progression

31 March 2020

1 reference

The Polo kinase Plk4 functions in centriole duplication

31 March 2020

1 reference

SAK/PLK4 is required for centriole duplication and flagella development

31 March 2020

1 reference

A genome-wide RNAi screen to dissect centriole duplication and centrosome maturation in Drosophila.

31 March 2020

1 reference

Acentriolar mitosis activates a p53-dependent apoptosis pathway in the mouse embryo

31 March 2020

1 reference

Lack of centrioles and primary cilia in STIL(-/-) mouse embryos

31 March 2020

1 reference

Cortical neurogenesis in the absence of centrioles.

31 March 2020

1 reference

Stabilization of cartwheel-less centrioles for duplication requires CEP295-mediated centriole-to-centrosome conversion

31 March 2020

1 reference

Cell biology. Reversible centriole depletion with an inhibitor of Polo-like kinase 4.

31 March 2020

1 reference

p53 protects against genome instability following centriole duplication failure

31 March 2020

1 reference

Centrosome function in cancer: guilty or innocent?

31 March 2020

1 reference

A clinical overview of centrosome amplification in human cancers

31 March 2020

1 reference

Causes and consequences of centrosome abnormalities in cancer

31 March 2020

1 reference

Centrosome amplification can initiate tumorigenesis in flies.

31 March 2020

1 reference

Centrosome dysfunction in Drosophila neural stem cells causes tumors that are not due to genome instability.

31 March 2020

1 reference

Centrosome hypertrophy in human breast tumors: implications for genomic stability and cell polarity

31 March 2020

1 reference

Centrosome amplification drives chromosomal instability in breast tumor development

31 March 2020

1 reference

Centrosomes, chromosome instability (CIN) and aneuploidy

31 March 2020

1 reference

Aneuploidy acts both oncogenically and as a tumor suppressor

31 March 2020

1 reference

Mitotic chromosomal instability and cancer: mouse modelling of the human disease.

31 March 2020

1 reference

Spindle multipolarity is prevented by centrosomal clustering.

31 March 2020

1 reference

Mechanisms to suppress multipolar divisions in cancer cells with extra centrosomes

31 March 2020

1 reference

A mechanism linking extra centrosomes to chromosomal instability

31 March 2020

1 reference

Multipolar spindle pole coalescence is a major source of kinetochore mis-attachment and chromosome mis-segregation in cancer cells

31 March 2020

1 reference

Centrosome amplification causes microcephaly

31 March 2020

1 reference

The autoregulated instability of Polo-like kinase 4 limits centrosome duplication to once per cell cycle

31 March 2020

1 reference

Cytokinesis failure triggers hippo tumor suppressor pathway activation.

31 March 2020

1 reference

Oncogenes and tumour suppressors take on centrosomes

31 March 2020

1 reference

Oncogene-like induction of cellular invasion from centrosome amplification

31 March 2020

1 reference

Centrosome amplification and the origin of chromosomal instability in breast cancer

31 March 2020

1 reference

Primary microcephaly: do all roads lead to Rome?

31 March 2020

1 reference

Cdk5rap2 exposes the centrosomal root of microcephaly syndromes

31 March 2020

1 reference

Molecular and cellular basis of autosomal recessive primary microcephaly

31 March 2020

1 reference

Small organelle, big responsibility: the role of centrosomes in development and disease

31 March 2020

1 reference

Cerebral organoids model human brain development and microcephaly

31 March 2020

1 reference

Cdk5rap2 interacts with pericentrin to maintain the neural progenitor pool in the developing neocortex

31 March 2020

1 reference

Neural stem cells: the need for a proper orientation

31 March 2020

1 reference

The cell biology of neurogenesis: toward an understanding of the development and evolution of the neocortex

31 March 2020

1 reference

Male gametogenesis without centrioles.

31 March 2020

1 reference

Mechanisms and pathways of growth failure in primordial dwarfism.

31 March 2020

1 reference

Centriole disassembly in vivo and its effect on centrosome structure and function in vertebrate cells

31 March 2020

1 reference

Centriole assembly in Caenorhabditis elegans

31 March 2020

1 reference

Sequential protein recruitment in C. elegans centriole formation

31 March 2020

1 reference

Towards a molecular architecture of centriole assembly

31 March 2020

1 reference

Mapping molecules to structure: unveiling secrets of centriole and cilia assembly with near-atomic resolution

31 March 2020

1 reference

The centriole duplication cycle

31 March 2020

1 reference

31 March 2020

1 reference

The C. elegans zyg-1 gene encodes a regulator of centrosome duplication with distinct maternal and paternal roles in the embryo

31 March 2020

1 reference

3D-structured illumination microscopy provides novel insight into architecture of human centrosomes

31 March 2020

1 reference

Centrosome maturation and duplication in C. elegans require the coiled-coil protein SPD-2.

31 March 2020

1 reference

The Caenorhabditis elegans centrosomal protein SPD-2 is required for both pericentriolar material recruitment and centriole duplication.

31 March 2020

1 reference

Drosophila asterless and vertebrate Cep152 Are orthologs essential for centriole duplication

31 March 2020

1 reference

Asterless is a scaffold for the onset of centriole assembly

31 March 2020

1 reference

Cep152 interacts with Plk4 and is required for centriole duplication.

31 March 2020

1 reference

Cep152 acts as a scaffold for recruitment of Plk4 and CPAP to the centrosome

31 March 2020

1 reference

Human Cep192 and Cep152 cooperate in Plk4 recruitment and centriole duplication

31 March 2020

1 reference

Hierarchical recruitment of Plk4 and regulation of centriole biogenesis by two centrosomal scaffolds, Cep192 and Cep152.

31 March 2020

1 reference

Direct binding of SAS-6 to ZYG-1 recruits SAS-6 to the mother centriole for cartwheel assembly

31 March 2020

1 reference

Plk4 phosphorylates Ana2 to trigger Sas6 recruitment and procentriole formation

31 March 2020

1 reference

Direct interaction of Plk4 with STIL ensures formation of a single procentriole per parental centriole.

31 March 2020

1 reference

Plk4-dependent phosphorylation of STIL is required for centriole duplication.

31 March 2020

1 reference

Structures of SAS-6 suggest its organization in centrioles

31 March 2020

1 reference

Structural Basis of the 9-Fold Symmetry of Centrioles

31 March 2020

1 reference

CPAP is a cell-cycle regulated protein that controls centriole length

31 March 2020

1 reference

The human microcephaly protein STIL interacts with CPAP and is required for procentriole formation

31 March 2020

1 reference

Bld10p, a novel protein essential for basal body assembly in Chlamydomonas: localization to the cartwheel, the first ninefold symmetrical structure appearing during assembly

31 March 2020

1 reference

Bld10p constitutes the cartwheel-spoke tip and stabilizes the 9-fold symmetry of the centriole

31 March 2020

1 reference

Human microcephaly protein CEP135 binds to hSAS-6 and CPAP, and is required for centriole assembly

31 March 2020

1 reference

Drosophila bld10 is a centriolar protein that regulates centriole, basal body, and motile cilium assembly

31 March 2020

1 reference

BLD10/CEP135 is a microtubule-associated protein that controls the formation of the flagellum central microtubule pair

31 March 2020

1 reference

Drosophila Cep135/Bld10 maintains proper centriole structure but is dispensable for cartwheel formation

31 March 2020

1 reference

Abnormal centrosomal structure and duplication in Cep135-deficient vertebrate cells

31 March 2020

1 reference

Asterless licenses daughter centrioles to duplicate for the first time in Drosophila embryos

31 March 2020

1 reference

Caenorhabditis elegans centriolar protein SAS-6 forms a spiral that is consistent with imparting a ninefold symmetry

31 March 2020

1 reference

Structure of the SAS-6 cartwheel hub from Leishmania major

31 March 2020

1 reference

The homo-oligomerisation of both Sas-6 and Ana2 is required for efficient centriole assembly in flies

31 March 2020

1 reference

The Caenorhabditis elegans protein SAS-5 forms large oligomeric assemblies critical for centriole formation

31 March 2020

1 reference

Molecular basis for unidirectional scaffold switching of human Plk4 in centriole biogenesis

31 March 2020

1 reference

Structure of the C. elegans ZYG-1 Cryptic Polo Box Suggests a Conserved Mechanism for Centriolar Docking of Plk4 Kinases

31 March 2020

1 reference

Crystal structures of the CPAP/STIL complex reveal its role in centriole assembly and human microcephaly

31 March 2020

1 reference

Structural Analysis of the G-Box Domain of the Microcephaly Protein CPAP Suggests a Role in Centriole Architecture

31 March 2020

1 reference

STIL binding to Polo-box 3 of PLK4 regulates centriole duplication

31 March 2020

1 reference

Binding of STIL to Plk4 activates kinase activity to promote centriole assembly

31 March 2020

1 reference

PLK2 phosphorylation is critical for CPAP function in procentriole formation during the centrosome cycle

31 March 2020

1 reference

GCP6 is a substrate of Plk4 and required for centriole duplication

31 March 2020

1 reference

A multicomponent assembly pathway contributes to the formation of acentrosomal microtubule arrays in interphase Drosophila cells

31 March 2020

1 reference

The subcellular organization of Madin-Darby canine kidney cells during the formation of a polarized epithelium

31 March 2020

1 reference

Nucleation and capture of large cell surface-associated microtubule arrays that are not located near centrosomes in certain cochlear epithelial cells

31 March 2020

1 reference

A developmentally regulated two-step process generates a noncentrosomal microtubule network in Drosophila tracheal cells.

31 March 2020

1 reference

A role for the centrosome and PAR-3 in the hand-off of MTOC function during epithelial polarization

31 March 2020

1 reference

Fate of microtubule-organizing centers during myogenesis in vitro

31 March 2020

1 reference

Centrosome proteins form an insoluble perinuclear matrix during muscle cell differentiation

31 March 2020

1 reference

Axon extension occurs independently of centrosomal microtubule nucleation.

31 March 2020

1 reference

The mammalian SPD-2 ortholog Cep192 regulates centrosome biogenesis

31 March 2020

1 reference

Plk1-dependent recruitment of gamma-tubulin complexes to mitotic centrosomes involves multiple PCM components

31 March 2020

1 reference

Polo-like kinase 1 regulates Nlp, a centrosome protein involved in microtubule nucleation

31 March 2020

1 reference

Centrobin controls mother-daughter centriole asymmetry in Drosophila neuroblasts

31 March 2020

1 reference

Subdiffraction-resolution fluorescence microscopy reveals a domain of the centrosome critical for pericentriolar material organization

31 March 2020

1 reference

Subdiffraction imaging of centrosomes reveals higher-order organizational features of pericentriolar material

31 March 2020

1 reference

Structured illumination of the interface between centriole and peri-centriolar material

31 March 2020

1 reference

Centriolar satellites: busy orbits around the centrosome

31 March 2020

1 reference

Centriolar satellites are assembly points for proteins implicated in human ciliopathies, including oral-facial-digital syndrome 1.

31 March 2020

1 reference

31 March 2020

Centrosome maturation

1 reference

Pattern formation in centrosome assembly

31 March 2020

1 reference

Amorphous no more: subdiffraction view of the pericentriolar material architecture

31 March 2020

1 reference

Pericentriolar material structure and dynamics

31 March 2020

1 reference

PLK1 phosphorylation of pericentrin initiates centrosome maturation at the onset of mitosis

31 March 2020

1 reference

The centrosome-specific phosphorylation of Cnn by Polo/Plk1 drives Cnn scaffold assembly and centrosome maturation.

31 March 2020

1 reference

The Plk1 target Kizuna stabilizes mitotic centrosomes to ensure spindle bipolarity

31 March 2020

1 reference

Aurora A phosphorylation of TACC3/maskin is required for centrosome-dependent microtubule assembly in mitosis

31 March 2020

1 reference

Aurora A activates D-TACC-Msps complexes exclusively at centrosomes to stabilize centrosomal microtubules

31 March 2020

1 reference

Nek9 phosphorylation of NEDD1/GCP-WD contributes to Plk1 control of γ-tubulin recruitment to the mitotic centrosome

31 March 2020

1 reference

Novel NEDD1 phosphorylation sites regulate γ-tubulin binding and mitotic spindle assembly.

31 March 2020

1 reference

Microtubule nucleating gamma-TuSC assembles structures with 13-fold microtubule-like symmetry

31 March 2020

1 reference

Ring closure activates yeast γTuRC for species-specific microtubule nucleation

31 March 2020

1 reference

Cell-cycle dependent phosphorylation of yeast pericentrin regulates γ-TuSC-mediated microtubule nucleation.

31 March 2020

1 reference

Targeting of γ-tubulin complexes to microtubule organizing centers: conservation and divergence

31 March 2020

1 reference

The disassembly and reassembly of functional centrosomes in vitro

31 March 2020

1 reference

Planting the seeds of biotechnology

31 March 2020

1 reference

Recruitment of the gamma-tubulin ring complex to Drosophila salt-stripped centrosome scaffolds

31 March 2020

1 reference

A molecular mechanism of mitotic centrosome assembly in Drosophila

31 March 2020

1 reference

Centrosomes. Regulated assembly of a supramolecular centrosome scaffold in vitro

31 March 2020

1 reference

Maintaining the proper connection between the centrioles and the pericentriolar matrix requires Drosophila centrosomin

31 March 2020

1 reference

Centrosome maturation and mitotic spindle assembly in C. elegans require SPD-5, a protein with multiple coiled-coil domains

31 March 2020

1 reference

The Drosophila pericentrin-like protein is essential for cilia/flagella function, but appears to be dispensable for mitosis

31 March 2020

1 reference

The Drosophila Pericentrin-like-protein (PLP) cooperates with Cnn to maintain the integrity of the outer PCM.

31 March 2020

1 reference

Interphase centrosome organization by the PLP-Cnn scaffold is required for centrosome function

31 March 2020

1 reference

Gamma-tubulin is required for the structure and function of the microtubule organizing centre in Drosophila neuroblasts.

31 March 2020

1 reference

The kinetically dominant assembly pathway for centrosomal asters in Caenorhabditis elegans is gamma-tubulin dependent

31 March 2020

1 reference

Sas-4 provides a scaffold for cytoplasmic complexes and tethers them in a centrosome

31 March 2020

1 reference

Tubulin nucleotide status controls Sas-4-dependent pericentriolar material recruitment

31 March 2020

1 reference

SAS-4 is a C. elegans centriolar protein that controls centrosome size

31 March 2020

1 reference

The Caenorhabditis elegans pericentriolar material components SPD-2 and SPD-5 are monomeric in the cytoplasm before incorporation into the PCM matrix

31 March 2020

1 reference

Cnn dynamics drive centrosome size asymmetry to ensure daughter centriole retention in Drosophila neuroblasts

31 March 2020

1 reference

Importance of the CEP215-pericentrin interaction for centrosome maturation during mitosis

31 March 2020

1 reference

Human Cep192 is required for mitotic centrosome and spindle assembly

31 March 2020

1 reference

The Cep192-organized aurora A-Plk1 cascade is essential for centrosome cycle and bipolar spindle assembly

31 March 2020

1 reference

CDK5RAP2 functions in centrosome to spindle pole attachment and DNA damage response

31 March 2020

1 reference

CDK5RAP2 stimulates microtubule nucleation by the gamma-tubulin ring complex.

31 March 2020

1 reference

Mitosis-specific anchoring of gamma tubulin complexes by pericentrin controls spindle organization and mitotic entry

31 March 2020

1 reference

CDK5RAP2 is a pericentriolar protein that functions in centrosomal attachment of the gamma-tubulin ring complex

31 March 2020

1 reference

Interaction of Aurora-A and centrosomin at the microtubule-nucleating site in Drosophila and mammalian cells

31 March 2020

1 reference

Bimodal Interaction of Mammalian Polo-Like Kinase 1 and a Centrosomal Scaffold, Cep192, in the Regulation of Bipolar Spindle Formation

31 March 2020

1 reference

CDK5RAP2 regulates centriole engagement and cohesion in mice

31 March 2020

1 reference

Separase-dependent cleavage of pericentrin B is necessary and sufficient for centriole disengagement during mitosis

31 March 2020

1 reference

Degradation of Cep68 and PCNT cleavage mediate Cep215 removal from the PCM to allow centriole separation, disengagement and licensing.

31 March 2020

1 reference

Cep68 and Cep215 (Cdk5rap2) are required for centrosome cohesion

31 March 2020

1 reference

The sudden recruitment of gamma-tubulin to the centrosome at the onset of mitosis and its dynamic exchange throughout the cell cycle, do not require microtubules

31 March 2020

1 reference

Dynamic recruitment of Nek2 kinase to the centrosome involves microtubules, PCM-1, and localized proteasomal degradation.

31 March 2020

1 reference

Centrioles regulate centrosome size by controlling the rate of Cnn incorporation into the PCM.

31 March 2020

1 reference

Different Drosophila cell types exhibit differences in mitotic centrosome assembly dynamics

31 March 2020

1 reference

Centrosomes are autocatalytic droplets of pericentriolar material organized by centrioles

31 March 2020

1 reference

Isotropic incorporation of SPD-5 underlies centrosome assembly in C. elegans

31 March 2020

1 reference

Separate to operate: control of centrosome positioning and separation.

31 March 2020

1 reference

Controlling centrosome number: licenses and blocks

31 March 2020

1 reference

The centrosome is a dynamic structure that ejects PCM flares.

31 March 2020

1 reference

A centriole-free Drosophila cell line. A high voltage EM study

31 March 2020

1 reference

12 December 2020

Centrosome defects and genetic instability in malignant tumors

1 reference

12 December 2020

Microtubule nucleation by gamma-tubulin-containing rings in the centrosome

1 reference

12 December 2020

The centrosomin protein is required for centrosome assembly and function during cleavage in Drosophila.

1 reference

12 December 2020

Identifiers

DOI

10.1038/NRM4062

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26373263%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

24 February 2020

1002965183

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Fatcat ID

release_d2psvkzn2zdo3e5xhqrdbv7rra

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/d2psvkzn2zdo3e5xhqrdbv7rra

24 November 2022

mapped directly with Wikidata item

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