(Q38608263)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26471369%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

title

From sewer to saviour - targeting the lymphatic system to promote drug exposure and activity (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26471369%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26471369%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

Lisa M. Kaminskas

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26471369%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

Christopher J.H. Porter

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26471369%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

author name string

Natalie L Trevaskis

1

1 reference

4 September 2017

Lisa M Kaminskas

2

1 reference

4 September 2017

Christopher J H Porter

3

1 reference

4 September 2017

language of work or name

1 reference

16 October 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26471369%20AND%20SRC:MED&resulttype=core&format=json

Nature Reviews Drug Discovery

27 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26471369%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

volume

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26471369%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

issue

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26471369%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

page(s)

781-803

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26471369%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/nrd4608

27 February 2020

exact match

0 references

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Interstitial fluid and lymph formation and transport: physiological regulation and roles in inflammation and cancer

31 March 2020

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On the Absorption of Fluids from the Connective Tissue Spaces

31 March 2020

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Microvascular fluid exchange and the revised Starling principle

31 March 2020

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New developments in clinical aspects of lymphatic disease

31 March 2020

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Emerging roles of lymphatic endothelium in regulating adaptive immunity

31 March 2020

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Oral tolerance to food protein

31 March 2020

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Angptl4 protects against severe proinflammatory effects of saturated fat by inhibiting fatty acid uptake into mesenteric lymph node macrophages

31 March 2020

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Mesenteric lymph nodes at the center of immune anatomy

31 March 2020

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Lymphatic lipid transport: sewer or subway?

31 March 2020

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Lymphatic vasculature mediates macrophage reverse cholesterol transport in mice

31 March 2020

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Lymphatic vessels are essential for the removal of cholesterol from peripheral tissues by SR-BI-mediated transport of HDL.

31 March 2020

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The link between lymphatic function and adipose biology.

31 March 2020

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Adipose tissue and the immune system

31 March 2020

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Lymphatic vascular defects promoted by Prox1 haploinsufficiency cause adult-onset obesity

31 March 2020

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Apelin inhibits diet-induced obesity by enhancing lymphatic and blood vessel integrity

31 March 2020

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Chronic high-fat diet impairs collecting lymphatic vessel function in mice

31 March 2020

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Reduced adipose tissue lymphatic drainage of macromolecules in obese subjects: a possible link between obesity and local tissue inflammation?

31 March 2020

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Obesity increases inflammation and impairs lymphatic function in a mouse model of lymphedema

31 March 2020

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Obesity impairs lymphatic fluid transport and dendritic cell migration to lymph nodes

31 March 2020

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Visceral fat accumulation induced by a high-fat diet causes the atrophy of mesenteric lymph nodes in obese mice

31 March 2020

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The lymphatic vasculature in disease

31 March 2020

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Lymphatic vessels in health and disease

31 March 2020

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Current views on the function of the lymphatic vasculature in health and disease

31 March 2020

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Lymphatic and interstitial flow in the tumour microenvironment: linking mechanobiology with immunity

31 March 2020

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Lymphatic vessels: new targets for the treatment of inflammatory diseases

31 March 2020

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Expansion of the lymphatic vasculature in cancer and inflammation: new opportunities for in vivo imaging and drug delivery.

31 March 2020

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Role of the lymphatic system in the pathogenesis of Crohn's disease

31 March 2020

1 reference

VEGF-C-dependent stimulation of lymphatic function ameliorates experimental inflammatory bowel disease

31 March 2020

1 reference

An important role of lymphatic vessel activation in limiting acute inflammation

31 March 2020

1 reference

Increased lymphangiogenesis in joints of mice with inflammatory arthritis

31 March 2020

1 reference

Macrophages regulate salt-dependent volume and blood pressure by a vascular endothelial growth factor-C-dependent buffering mechanism

31 March 2020

1 reference

Increased nitric oxide production in lymphatic endothelial cells causes impairment of lymphatic drainage in cirrhotic rats.

31 March 2020

1 reference

An overview of lymphatic vessels and their emerging role in cardiovascular disease

31 March 2020

1 reference

Persistent HIV-1 replication is associated with lower antiretroviral drug concentrations in lymphatic tissues

31 March 2020

1 reference

Lymphoid organs function as major reservoirs for human immunodeficiency virus

31 March 2020

1 reference

Association between persistent lymphatic infection by hepatitis C virus after antiviral treatment and mixed cryoglobulinemia

31 March 2020

1 reference

Lymphangiogenesis and lymphatic remodeling induced by filarial parasites: implications for pathogenesis

31 March 2020

1 reference

31 March 2020

Ebola haemorrhagic fever

1 reference

Gut lymph and lymphatics: a source of factors leading to organ injury and dysfunction

31 March 2020

1 reference

Lymphatic endothelial progenitor cells contribute to de novo lymphangiogenesis in human renal transplants.

31 March 2020

1 reference

Mechanism of oral tolerance induction to therapeutic proteins

31 March 2020

1 reference

Engineering approaches to immunotherapy.

31 March 2020

1 reference

Lipid-based delivery systems and intestinal lymphatic drug transport: a mechanistic update

31 March 2020

1 reference

Nano-chemotherapeutics: maximising lymphatic drug exposure to improve the treatment of lymph-metastatic cancers.

31 March 2020

1 reference

Intestinal lymphatic transport for drug delivery

31 March 2020

1 reference

Effect of molecular weight on the lymphatic absorption of water-soluble compounds following subcutaneous administration

31 March 2020

1 reference

Engineering synthetic vaccines using cues from natural immunity

31 March 2020

1 reference

Lymphatic absorption is a significant contributor to the subcutaneous bioavailability of insulin in a sheep model

31 March 2020

1 reference

Systemic availability and lymphatic transport of human growth hormone administered by subcutaneous injection

31 March 2020

1 reference

Lymphatic Absorption of Subcutaneously Administered Proteins: Influence of Different Injection Sites on the Absorption of Darbepoetin Alfa Using a Sheep Model

31 March 2020

1 reference

Pharmacokinetic model to describe the lymphatic absorption of r-metHu-leptin after subcutaneous injection to sheep

31 March 2020

1 reference

The absorption of darbepoetin alfa occurs predominantly via the lymphatics following subcutaneous administration to sheep.

31 March 2020

1 reference

Lymphatic absorption is the primary contributor to the systemic availability of epoetin Alfa following subcutaneous administration to sheep.

31 March 2020

1 reference

Lymphatic uptake and biodistribution of liposomes after subcutaneous injection. II. Influence of liposomal size, lipid compostion and lipid dose

31 March 2020

1 reference

Exploiting lymphatic transport and complement activation in nanoparticle vaccines

31 March 2020

1 reference

Demonstration of ATP-dependent, transcellular transport of lipid across the lymphatic endothelium using an in vitro model of the lacteal.

31 March 2020

1 reference

Antitumor activity of a homing peptide that targets tumor lymphatics and tumor cells

31 March 2020

1 reference

A tumor-homing peptide with a targeting specificity related to lymphatic vessels

31 March 2020

1 reference

Plasma-lymph exchange and interstitial distribution volumes of charged macromolecules in the lung.

31 March 2020

1 reference

Diffusion of particles in the extracellular matrix: the effect of repulsive electrostatic interactions

31 March 2020

1 reference

PEGylation of polylysine dendrimers improves absorption and lymphatic targeting following SC administration in rats

31 March 2020

1 reference

Biodegradable PLGA based nanoparticles for sustained regional lymphatic drug delivery

31 March 2020

1 reference

Microneedle-based intradermal delivery enables rapid lymphatic uptake and distribution of protein drugs

31 March 2020

1 reference

Intradermal vaccine delivery: will new delivery systems transform vaccine administration?

31 March 2020

1 reference

Intradermal, epidermal and transcutaneous vaccination: from immunology to clinical practice

31 March 2020

1 reference

Roles of dextrans on improving lymphatic drainage for liposomal drug delivery system

31 March 2020

1 reference

Structure-based programming of lymph-node targeting in molecular vaccines

31 March 2020

1 reference

Hyaluronic acid-polyethyleneimine conjugate for target specific intracellular delivery of siRNA.

31 March 2020

1 reference

Mitochondrial/cell-surface protein p32/gC1qR as a molecular target in tumor cells and tumor stroma

31 March 2020

1 reference

Targeting of albumin-embedded paclitaxel nanoparticles to tumors

31 March 2020

1 reference

LyP-1-conjugated nanoparticles for targeting drug delivery to lymphatic metastatic tumors

31 March 2020

1 reference

LyP-1-conjugated PEGylated liposomes: a carrier system for targeted therapy of lymphatic metastatic tumor.

31 March 2020

1 reference

Integrins in cancer: biological implications and therapeutic opportunities

31 March 2020

1 reference

Harnessing biomaterials to engineer the lymph node microenvironment for immunity or tolerance.

31 March 2020

1 reference

Cationic micelle delivery of Trp2 peptide for efficient lymphatic draining and enhanced cytotoxic T-lymphocyte responses.

31 March 2020

1 reference

Lymphatic-targeted cationic liposomes: a robust vaccine adjuvant for promoting long-term immunological memory.

31 March 2020

1 reference

In vivo targeting of dendritic cells for activation of cellular immunity using vaccine carriers based on pH-responsive microparticles

31 March 2020

1 reference

The Lymphatic System Plays a Major Role in the Intravenous and Subcutaneous Pharmacokinetics of Trastuzumab in Rats

31 March 2020

1 reference

PEGylated polylysine dendrimers increase lymphatic exposure to doxorubicin when compared to PEGylated liposomal and solution formulations of doxorubicin

31 March 2020

1 reference

Lipid-calcium phosphate nanoparticles for delivery to the lymphatic system and SPECT/CT imaging of lymph node metastases

31 March 2020

1 reference

Brain-wide pathway for waste clearance captured by contrast-enhanced MRI

31 March 2020

1 reference

A paravascular pathway facilitates CSF flow through the brain parenchyma and the clearance of interstitial solutes, including amyloid β.

31 March 2020

1 reference

Cerebral arterial pulsation drives paravascular CSF-interstitial fluid exchange in the murine brain

31 March 2020

1 reference

Sleep drives metabolite clearance from the adult brain

31 March 2020

1 reference

Evaluating glymphatic pathway function utilizing clinically relevant intrathecal infusion of CSF tracer

31 March 2020

1 reference

A dural lymphatic vascular system that drains brain interstitial fluid and macromolecules

31 March 2020

1 reference

Structural and functional features of central nervous system lymphatic vessels

31 March 2020

1 reference

Rationale and applications of lipids as prodrug carriers

31 March 2020

1 reference

Gut-associated lymphoid tissues for the development of oral vaccines

31 March 2020

1 reference

Oral delivery of proteins by biodegradable nanoparticles

31 March 2020

1 reference

Nanoparticle uptake by the oral route: Fulfilling its potential?

31 March 2020

1 reference

Intestinal lymphatic transport of halofantrine occurs after oral administration of a unit-dose lipid-based formulation to fasted dogs

31 March 2020

1 reference

Effect of short-, medium-, and long-chain fatty acid-based vehicles on the absolute oral bioavailability and intestinal lymphatic transport of halofantrine and assessment of mass balance in lymph-cannulated and non-cannulated rats

31 March 2020

1 reference

A mouse model to evaluate the impact of species, sex, and lipid load on lymphatic drug transport

31 March 2020

1 reference

The mechanism of lymphatic access of two cholesteryl ester transfer protein inhibitors (CP524,515 and CP532,623) and evaluation of their impact on lymph lipoprotein profiles

31 March 2020

1 reference

The role of lymphatic transport on the systemic bioavailability of the Bcl-2 protein family inhibitors navitoclax (ABT-263) and ABT-199.

31 March 2020

1 reference

The role of molecular physicochemical properties and apolipoproteins in association of drugs with triglyceride-rich lipoproteins: in-silico prediction of uptake by chylomicrons

31 March 2020

1 reference

Uptake of lipophilic drugs by plasma derived isolated chylomicrons: linear correlation with intestinal lymphatic bioavailability

31 March 2020

1 reference

Exploring the Impact of Drug Properties on the Extent of Intestinal Lymphatic Transport - In Vitro and In Vivo Studies

31 March 2020

1 reference

Biomimetic reassembled chylomicrons as novel association model for the prediction of lymphatic transportation of highly lipophilic drugs via the oral route.

31 March 2020

1 reference

Successful in silico predicting of intestinal lymphatic transfer

31 March 2020

1 reference

Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

31 March 2020

1 reference

The role of ligand efficiency metrics in drug discovery.

31 March 2020

1 reference

Targeted delivery of a model immunomodulator to the lymphatic system: comparison of alkyl ester versus triglyceride mimetic lipid prodrug strategies

31 March 2020

1 reference

Studies on intestinal lymphatic absorption of drugs. I. Lymphatic absorption of alkyl ester derivatives and alpha-monoglyceride derivatives of drugs

31 March 2020

1 reference

Studies on intestinal lymphatic absorption of drugs. II. Glyceride prodrugs for improving lymphatic absorption of naproxen and nicotinic acid

31 March 2020

1 reference

The oral absorption of phospholipid prodrugs: in vivo and in vitro mechanistic investigation of trafficking of a lecithin-valproic acid conjugate following oral administration

31 March 2020

1 reference

Deacylation-reacylation cycle: a possible absorption mechanism for the novel lymphotropic antitumor agent dipalmitoylphosphatidylfluorouridine in rats

31 March 2020

1 reference

Recent advances in the understanding of uptake of microparticulates across the gastrointestinal lymphatics

31 March 2020

1 reference

Nanoparticles for oral delivery: targeted nanoparticles with peptidic ligands for oral protein delivery

31 March 2020

1 reference

Immunology of Gut Mucosal Vaccines

31 March 2020

1 reference

Oral delivery system prolongs blood circulation of docetaxel nanocapsules via lymphatic absorption

31 March 2020

1 reference

Transepithelial transport of Fc-targeted nanoparticles by the neonatal fc receptor for oral delivery

31 March 2020

1 reference

Mucosal vaccines: the promise and the challenge

31 March 2020

1 reference

Intestinal CD103+, but not CX3CR1+, antigen sampling cells migrate in lymph and serve classical dendritic cell functions.

31 March 2020

1 reference

Intestinal dendritic cells

31 March 2020

1 reference

CX3CR1-mediated dendritic cell access to the intestinal lumen and bacterial clearance

31 March 2020

1 reference

Lectin-mediated mucosal delivery of drugs and microparticles

31 March 2020

1 reference

Utilizing bacterial mechanisms of epithelial cell entry: invasin-induced oral uptake of latex nanoparticles

31 March 2020

1 reference

Targeting nanoparticles to M cells with non-peptidic ligands for oral vaccination

31 March 2020

1 reference

Goblet cell-targeting nanoparticles for oral insulin delivery and the influence of mucus on insulin transport

31 March 2020

1 reference

Unique insights into the intestinal absorption, transit, and subsequent biodistribution of polymer-derived microspheres

31 March 2020

1 reference

Gastrointestinal uptake of biodegradable microparticles: effect of particle size

31 March 2020

1 reference

Nanoparticle uptake by the rat gastrointestinal mucosa: quantitation and particle size dependency

31 March 2020

1 reference

A method for quantifying particle absorption from the small intestine of the mouse

31 March 2020

1 reference

Enhanced oral uptake of tomato lectin-conjugated nanoparticles in the rat

31 March 2020

1 reference

Novel self assembling nanoparticles for the oral administration of fondaparinux: synthesis, characterization and in vivo evaluation

31 March 2020

1 reference

Lectin-modified solid lipid nanoparticles as carriers for oral administration of insulin

31 March 2020

1 reference

Oral uptake and translocation of a polylysine dendrimer with a lipid surface

31 March 2020

1 reference

Pulmonary administration of PEGylated polylysine dendrimers: absorption from the lung versus retention within the lung is highly size-dependent

31 March 2020

1 reference

Recent progress in mucosal vaccine development: potential and limitations

31 March 2020

1 reference

Exploiting mucosal surfaces for the development of mucosal vaccines.

31 March 2020

1 reference

PPS nanoparticles as versatile delivery system to induce systemic and broad mucosal immunity after intranasal administration.

31 March 2020

1 reference

Nanoparticle size influences the magnitude and quality of mucosal immune responses after intranasal immunization

31 March 2020

1 reference

Biodegradable polymeric nanocarriers for pulmonary drug delivery

31 March 2020

1 reference

The lungs as a portal of entry for systemic drug delivery

31 March 2020

1 reference

Lung lymphatic anatomy and correlates.

31 March 2020

1 reference

Bronchus-associated lymphoid tissue: an entry site for antigens for successful mucosal vaccinations?

31 March 2020

1 reference

Update on macrophage clearance of inhaled micro- and nanoparticles

31 March 2020

1 reference

Mucociliary clearance in the airways

31 March 2020

1 reference

Intralobular pulmonary lymphatic distribution in normal human lung using D2-40 antipodoplanin immunostaining

31 March 2020

1 reference

Visualização da Rede Linfática Pulmonar Profunda usando Radioliposomas

31 March 2020

1 reference

Molecular weight-dependent lymphatic transfer of fluorescein isothiocyanate-labeled dextrans after intrapulmonary administration and effects of various absorption enhancers on the lymphatic transfer of drugs in rats

31 March 2020

1 reference

Rapid translocation of nanoparticles from the lung airspaces to the body

31 March 2020

1 reference

Lymphatic uptake of pulmonary delivered radiolabelled solid lipid nanoparticles

31 March 2020

1 reference

Aerosol delivery of liposomal formulated paclitaxel and vitamin E analog reduces murine mammary tumor burden and metastases

31 March 2020

1 reference

Rapid lymph accumulation of polystyrene nanoparticles following pulmonary administration.

31 March 2020

1 reference

Naive and memory T cells show distinct pathways of lymphocyte recirculation

31 March 2020

1 reference

Afferent lymph-derived T cells and DCs use different chemokine receptor CCR7-dependent routes for entry into the lymph node and intranodal migration

31 March 2020

1 reference

Subcutaneous and intravenous delivery of diagnostic agents to the lymphatic system: applications in lymphoscintigraphy and indirect lymphography

31 March 2020

1 reference

Accumulation of fingolimod (FTY720) in lymphoid tissues contributes to prolonged efficacy

31 March 2020

1 reference

Nanoparticles target distinct dendritic cell populations according to their size

31 March 2020

1 reference

Surface engineered nanospheres with enhanced drainage into lymphatics and uptake by macrophages of the regional lymph nodes

31 March 2020

1 reference

Lymphatic uptake and biodistribution of liposomes after subcutaneous injection . IV. Fate of liposomes in regional lymph nodes

31 March 2020

1 reference

In vivo targeting of dendritic cells in lymph nodes with poly(propylene sulfide) nanoparticles.

31 March 2020

1 reference

The conduit system transports soluble antigens from the afferent lymph to resident dendritic cells in the T cell area of the lymph node

31 March 2020

1 reference

Synthetic CD4+ T cell-targeted antigen-presenting cells elicit protective antitumor responses

31 March 2020

1 reference

Enhancing humoral responses to a malaria antigen with nanoparticle vaccines that expand Tfh cells and promote germinal center induction

31 March 2020

1 reference

Liposomes to target the lymphatics by subcutaneous administration

31 March 2020

1 reference

Lymphatic delivery and pharmacokinetics of methotrexate after intramuscular injection of differently charged liposome-entrapped methotrexate to rats

31 March 2020

1 reference

Methotrexate-conjugated PEGylated dendrimers show differential patterns of deposition and activity in tumor-burdened lymph nodes after intravenous and subcutaneous administration in rats

31 March 2020

1 reference

Advances in lymphatic imaging and drug delivery.

31 March 2020

1 reference

Contribution of lymphatically transported testosterone undecanoate to the systemic exposure of testosterone after oral administration of two andriol formulations in conscious lymph duct-cannulated dogs.

31 March 2020

1 reference

Lymphatic transport of Methylnortestosterone undecanoate (MU) and the bioavailability of methylnortestosterone are highly sensitive to the mass of coadministered lipid after oral administration of MU.

31 March 2020

1 reference

Single, escalating dose pharmacokinetics, safety and food effects of a new oral androgen dimethandrolone undecanoate in man: a prototype oral male hormonal contraceptive

31 March 2020

1 reference

A conscious dog model for assessing the absorption, enterocyte-based metabolism, and intestinal lymphatic transport of halofantrine.

31 March 2020

1 reference

Intestinal lymphatic transport enhances the post-prandial oral bioavailability of a novel cannabinoid receptor agonist via avoidance of first-pass metabolism.

31 March 2020

1 reference

An examination of the interplay between enterocyte-based metabolism and lymphatic drug transport in the rat.

31 March 2020

1 reference

A self-assembled nanocarrier loading teniposide improves the oral delivery and drug concentration in tumor

31 March 2020

1 reference

1,3-dipalmitoylglycerol ester of chlorambucil as a lymphotropic, orally administrable antineoplastic agent

31 March 2020

1 reference

PEGylation of interferon α2 improves lymphatic exposure after subcutaneous and intravenous administration and improves antitumour efficacy against lymphatic breast cancer metastases.

31 March 2020

1 reference

Feasibility of eradication of breast cancer cells remaining in postlumpectomy cavity and draining lymph nodes following intracavitary injection of radioactive immunoliposomes

31 March 2020

1 reference

Carrier-based intralymphatic cisplatin chemotherapy for the treatment of metastatic squamous cell carcinoma of the head & neck.

31 March 2020

1 reference

Polymeric micelles for enhanced lymphatic drug delivery to treat metastatic tumors

31 March 2020

1 reference

Polymeric micelles incorporating (1,2-diaminocyclohexane)platinum (II) suppress the growth of orthotopic scirrhous gastric tumors and their lymph node metastasis.

31 March 2020

1 reference

Peripherally administered nanoparticles target monocytic myeloid cells, secondary lymphoid organs and tumors in mice

31 March 2020

1 reference

Prevention of nodal metastases in breast cancer following the lymphatic migration of paclitaxel-loaded expansile nanoparticles.

31 March 2020

1 reference

Intralymphatic chemotherapy using a hyaluronan-cisplatin conjugate.

31 March 2020

1 reference

Chemotherapy targeting regional lymph nodes by gastric submucosal injection of liposomal adriamycin in patients with gastric carcinoma.

31 March 2020

1 reference

Nanoparticle migration and delivery of Paclitaxel to regional lymph nodes in a large animal model

31 March 2020

1 reference

Lymphatic chemotherapy induces apoptosis in lymph node metastases in a rabbit breast carcinoma model

31 March 2020

1 reference

Magnetic functionalised carbon nanotubes as drug vehicles for cancer lymph node metastasis treatment

31 March 2020

1 reference

Local targeted therapy of liver metastasis from colon cancer by galactosylated liposome encapsulated with doxorubicin

31 March 2020

1 reference

Nano-sized drug-loaded micelles deliver payload to lymph node immune cells and prolong allograft survival

31 March 2020

1 reference

Targeted drug delivery to lymphocytes: a route to site-specific immunomodulation?

31 March 2020

1 reference

Efficacy of topical blockade of interleukin-1 in experimental dry eye disease

31 March 2020

1 reference

Interleukin-6 signalling regulates vascular endothelial growth factor-C synthesis and lymphangiogenesis in human oral squamous cell carcinoma

31 March 2020

1 reference

Tumour necrosis factor blockade increases lymphangiogenesis in murine and human arthritic joints

31 March 2020

1 reference

The role of the lymphatic system in vaccine trafficking and immune response

31 March 2020

1 reference

Trans-nodal migration of resident dendritic cells into medullary interfollicular regions initiates immunity to influenza vaccine

31 March 2020

1 reference

Intralymphatic immunotherapy

31 March 2020

1 reference

Intralymphatic allergen administration renders specific immunotherapy faster and safer: a randomized controlled trial

31 March 2020

1 reference

In situ engineering of the lymph node microenvironment via intranodal injection of adjuvant-releasing polymer particles

31 March 2020

1 reference

Intralymphatic immunization enhances DNA vaccination.

31 March 2020

1 reference

Nanoparticle conjugation of CpG enhances adjuvancy for cellular immunity and memory recall at low dose.

31 March 2020

1 reference

Multifunctional nanoparticles co-delivering Trp2 peptide and CpG adjuvant induce potent cytotoxic T-lymphocyte response against melanoma and its lung metastasis.

31 March 2020

1 reference

Interbilayer-crosslinked multilamellar vesicles as synthetic vaccines for potent humoral and cellular immune responses

31 March 2020

1 reference

Synthetic mast-cell granules as adjuvants to promote and polarize immunity in lymph nodes

31 March 2020

1 reference

Enhancing efficacy of anticancer vaccines by targeted delivery to tumor-draining lymph nodes

31 March 2020

1 reference

Targeting the tumor-draining lymph node with adjuvanted nanoparticles reshapes the anti-tumor immune response

31 March 2020

1 reference

Mucosal Immune System and M Cell-targeting Strategies for Oral Mucosal Vaccination

31 March 2020

1 reference

Large intestine-targeted, nanoparticle-releasing oral vaccine to control genitorectal viral infection

31 March 2020

1 reference

Nanoparticle conjugation and pulmonary delivery enhance the protective efficacy of Ag85B and CpG against tuberculosis

31 March 2020

1 reference

Nanoparticle conjugation of antigen enhances cytotoxic T-cell responses in pulmonary vaccination

31 March 2020

1 reference

Oral tolerance: therapeutic implications for autoimmune diseases

31 March 2020

1 reference

Antigen-specific tolerance strategies for the prevention and treatment of autoimmune disease

31 March 2020

1 reference

31 March 2020

1 reference

Induced immune tolerance for kidney transplantation

31 March 2020

1 reference

31 March 2020

1 reference

Oral tolerance, food allergy, and immunotherapy: implications for future treatment

31 March 2020

1 reference

Oral tolerance originates in the intestinal immune system and relies on antigen carriage by dendritic cells

31 March 2020

1 reference

Mesenteric lymph nodes are critical for the induction of high-dose oral tolerance in the absence of Peyer's patches.

31 March 2020

1 reference

Induction of oral tolerance to cellular immune responses in the absence of Peyer's patches

31 March 2020

1 reference

Induction of mucosal tolerance in Peyer's patch-deficient, ligated small bowel loops

31 March 2020

1 reference

Peyer's patches are required for oral tolerance to proteins

31 March 2020

1 reference

Ovalbumin-protein sigma 1 M-cell targeting facilitates oral tolerance with reduction of antigen-specific CD4+ T cells

31 March 2020

1 reference

Oral delivery of antigens in liposomes with some lipid compositions modulates oral tolerance to the antigens

31 March 2020

1 reference

The level of BLyS (BAFF) correlates with the titre of autoantibodies in human Sjögren's syndrome

31 March 2020

1 reference

Attenuation of transplant arteriosclerosis by oral feeding of major histocompatibility complex encoding chitosan-DNA nanoparticles

31 March 2020

1 reference

Oral tolerance elicited in mice by beta-lactoglobulin entrapped in biodegradable microspheres

31 March 2020

1 reference

Nanoparticle delivery of mycophenolic acid upregulates PD-L1 on dendritic cells to prolong murine allograft survival

31 March 2020

1 reference

Polymeric synthetic nanoparticles for the induction of antigen-specific immunological tolerance

31 March 2020

1 reference

Antigen-specific suppression of inflammatory arthritis using liposomes.

31 March 2020

1 reference

Microparticles bearing encephalitogenic peptides induce T-cell tolerance and ameliorate experimental autoimmune encephalomyelitis

31 March 2020

1 reference

Lipid–Drug Association Enhanced HIV-1 Protease Inhibitor Indinavir Localization in Lymphoid Tissues and Viral Load Reduction: A Proof of Concept Study in HIV-2287-Infected Macaques

31 March 2020

1 reference

Long-acting three-drug combination anti-HIV nanoparticles enhance drug exposure in primate plasma and cells within lymph nodes and blood

31 March 2020

1 reference

Anti-HIV drug particles may overcome lymphatic drug insufficiency and associated HIV persistence

31 March 2020

1 reference

Nanotechnology-based systems for the treatment and prevention of HIV/AIDS.

31 March 2020

1 reference

Development of HIV reservoir targeted long acting nanoformulated antiretroviral therapies

31 March 2020

1 reference

Drug delivery systems in HIV pharmacotherapy: what has been done and the challenges standing ahead.

31 March 2020

1 reference

Synthesis and biological evaluation of two glycerolipidic prodrugs of didanosine for direct lymphatic delivery against HIV

31 March 2020

1 reference

A new nanomedicine based on didanosine glycerolipidic prodrug enhances the long term accumulation of drug in a HIV sanctuary

31 March 2020

1 reference

Pharmacodynamics of long-acting folic acid-receptor targeted ritonavir-boosted atazanavir nanoformulations

31 March 2020

1 reference

Lymphatic absorption and metabolism of orally administered testosterone undecanoate in man

31 March 2020

1 reference

Animal models for the study of intestinal lymphatic drug transport

31 March 2020

1 reference

Images in clinical medicine. Ultrasound imaging of the thoracic duct

31 March 2020

1 reference

Overcoming transport barriers for interstitial-, lymphatic-, and lymph node-targeted drug delivery

31 March 2020

1 reference

Transmural flow modulates cell and fluid transport functions of lymphatic endothelium

31 March 2020

1 reference

LYVE-1, a new homologue of the CD44 glycoprotein, is a lymph-specific receptor for hyaluronan

31 March 2020

1 reference

A tissue-engineered model of the intestinal lacteal for evaluating lipid transport by lymphatics

31 March 2020

1 reference

Quantitative analysis of albumin uptake and transport in the rat microvessel endothelial monolayer.

31 March 2020

1 reference

Caveolae-deficient Endothelial Cells Show Defects in the Uptake and Transport of Albuminin Vivo

31 March 2020

1 reference

Sleep facilitates clearance of metabolites from the brain: glymphatic function in aging and neurodegenerative diseases

31 March 2020

1 reference

Paravascular microcirculation facilitates rapid lipid transport and astrocyte signaling in the brain

31 March 2020

1 reference

Transcytosis of nanoparticle and dendrimer delivery systems: evolving vistas

31 March 2020

1 reference

Nanoparticles as potential oral delivery systems of proteins and vaccines: a mechanistic approach.

31 March 2020

1 reference

Polymeric particulate technologies for oral drug delivery and targeting: a pathophysiological perspective

31 March 2020

1 reference

Lipid nanoparticles for oral delivery of raloxifene: optimization, stability, in vivo evaluation and uptake mechanism.

31 March 2020

1 reference

Intestinal absorption and intestinal lymphatic transport of sirolimus from self-microemulsifying drug delivery systems assessed using the single-pass intestinal perfusion (SPIP) technique and a chylomicron flow blocking approach: linear correlation w

31 March 2020

1 reference

Bile salts enhance the intestinal absorption of lipophilic drug loaded lipid nanocarriers: mechanism and effect in rats

31 March 2020

1 reference

The absorption, distribution, excretion and toxicity of mesoporous silica nanoparticles in mice following different exposure routes

31 March 2020

1 reference

Evaluation of a chylomicron flow blocking approach to investigate the intestinal lymphatic transport of lipophilic drugs

31 March 2020

1 reference

Interaction of tumor cells and lymphatic vessels in cancer progression

31 March 2020

1 reference

Hypercholesterolemic mice exhibit lymphatic vessel dysfunction and degeneration

31 March 2020

1 reference

Impaired lymphatic contraction associated with immunosuppression

31 March 2020

1 reference

Lymphatic trafficking kinetics and near-infrared imaging using star polymer architectures with controlled anionic character

31 March 2020

1 reference

"Tolerosomes" are produced by intestinal epithelial cells

31 March 2020

1 reference

Multiple facets of intestinal permeability and epithelial handling of dietary antigens

31 March 2020

1 reference

Chylomicrons promote intestinal absorption and systemic dissemination of dietary antigen (ovalbumin) in mice

31 March 2020

1 reference

Intestinal villous M cells: an antigen entry site in the mucosal epithelium

31 March 2020

1 reference

The impact of lymphatic transport on the systemic disposition of lipophilic drugs.

31 March 2020

1 reference

B cells acquire particulate antigen in a macrophage-rich area at the boundary between the follicle and the subcapsular sinus of the lymph node

31 March 2020

1 reference

Subcapsular sinus macrophages in lymph nodes clear lymph-borne viruses and present them to antiviral B cells

31 March 2020

1 reference

Enhanced lymphatic delivery of mitomycin C conjugated with dextran

31 March 2020

1 reference

12 December 2020

The lymphatic route. IX. Distribution of recombinant interferon-alpha 2 administered subcutaneously with oedematogenic drugs

1 reference

12 December 2020

Thoracic duct embolization for the management of chylothoraces

1 reference

12 December 2020

Generation of effector memory T cell-based mucosal and systemic immunity with pulmonary nanoparticle vaccination

1 reference

12 December 2020

TNF-alpha drives remodeling of blood vessels and lymphatics in sustained airway inflammation in mice

1 reference

12 December 2020

[Biochemical and ultrastructural study of actidione-cycloheximide effect on fat intestinal absorption in the rat (author's transl)]

1 reference

12 December 2020

Exploitation of the Macrophage Mannose Receptor (CD206) in Infectious Disease Diagnostics and Therapeutics.

1 reference

12 December 2020

The lymphatic route. VI. Distribution of recombinant interferon-alpha 2 in rabbit and pig plasma and lymph

1 reference

12 December 2020