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Tau Immunotherapy
scientific article
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Statements
instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PMCID
4777344
retrieved
4 September 2017
title
Tau Immunotherapy
(English)
1 reference
stated in
Europe PubMed Central
PMCID
4777344
retrieved
4 September 2017
main subject
immunotherapy
1 reference
based on heuristic
inferred from title
author
Einar M Sigurdsson
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMCID
4777344
retrieved
4 September 2017
publication date
10 November 2015
1 reference
stated in
Europe PubMed Central
PMCID
4777344
retrieved
4 September 2017
published in
Neurodegenerative Diseases
1 reference
stated in
Europe PubMed Central
PMCID
4777344
retrieved
4 September 2017
volume
16
1 reference
stated in
Europe PubMed Central
PMCID
4777344
retrieved
4 September 2017
issue
1-2
1 reference
stated in
Europe PubMed Central
PMCID
4777344
retrieved
4 September 2017
page(s)
34-38
1 reference
stated in
Europe PubMed Central
PMCID
4777344
retrieved
4 September 2017
cites work
Passive immunization with phospho-tau antibodies reduces tau pathology and functional deficits in two distinct mouse tauopathy models
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777344
retrieved
6 September 2017
Tau immunotherapy for Alzheimer's disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777344
retrieved
6 September 2017
Passive immunotherapy of tauopathy targeting pSer413-tau: a pilot study in mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777344
retrieved
6 September 2017
Antibody-derived in vivo imaging of tau pathology
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777344
retrieved
6 September 2017
First-in-man tau vaccine targeting structural determinants essential for pathological tau-tau interaction reduces tau oligomerisation and neurofibrillary degeneration in an Alzheimer's disease model
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777344
retrieved
6 September 2017
Epitope analysis following active immunization with tau proteins reveals immunogens implicated in tau pathogenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777344
retrieved
6 September 2017
Harnessing the immune system for treatment and detection of tau pathology.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777344
retrieved
6 September 2017
Antibody uptake into neurons occurs primarily via clathrin-dependent Fcγ receptor endocytosis and is a prerequisite for acute tau protein clearance.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777344
retrieved
6 September 2017
Two novel Tau antibodies targeting the 396/404 region are primarily taken up by neurons and reduce Tau protein pathology
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777344
retrieved
6 September 2017
Imaging of tau pathology in a tauopathy mouse model and in Alzheimer patients compared to normal controls
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777344
retrieved
6 September 2017
Efficacy and safety of a liposome-based vaccine against protein Tau, assessed in tau.P301L mice that model tauopathy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777344
retrieved
6 September 2017
Tau passive immunotherapy in mutant P301L mice: antibody affinity versus specificity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777344
retrieved
6 September 2017
Tau-targeted immunization impedes progression of neurofibrillary histopathology in aged P301L tau transgenic mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777344
retrieved
6 September 2017
Passive immunization with anti-Tau antibodies in two transgenic models: reduction of Tau pathology and delay of disease progression.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777344
retrieved
6 September 2017
Passive immunization targeting pathological phospho-tau protein in a mouse model reduces functional decline and clears tau aggregates from the brain
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777344
retrieved
6 September 2017
Engineering the variable region of therapeutic IgG antibodies.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777344
retrieved
6 September 2017
Immunotherapy targeting pathological tau prevents cognitive decline in a new tangle mouse model
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777344
retrieved
6 September 2017
Immunotherapy targeting pathological tau protein in Alzheimer's disease and related tauopathies.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777344
retrieved
6 September 2017
Targeting phospho-Ser422 by active Tau Immunotherapy in the THYTau22 mouse model: a suitable therapeutic approach
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777344
retrieved
14 September 2017
Immunotherapy targeting pathological tau conformers in a tangle mouse model reduces brain pathology with associated functional improvements.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777344
retrieved
14 September 2017
[(18)F]THK-5117 PET for assessing neurofibrillary pathology in Alzheimer's disease.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777344
retrieved
31 August 2018
Tau immunization: a cautionary tale?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777344
retrieved
31 August 2018
Human secreted tau increases amyloid-beta production
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777344
retrieved
31 August 2018
Tau-targeting passive immunization modulates aspects of pathology in tau transgenic mice.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777344
retrieved
31 August 2018
Non-invasive assessment of Alzheimer's disease neurofibrillary pathology using 18F-THK5105 PET.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777344
retrieved
31 August 2018
Anti-tau antibodies that block tau aggregate seeding in vitro markedly decrease pathology and improve cognition in vivo.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777344
retrieved
31 August 2018
Early clinical PET imaging results with the novel PHF-tau radioligand [F18]-T808.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777344
retrieved
31 August 2018
Repeated immunization of mice with phosphorylated-tau peptides causes neuroinflammation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777344
retrieved
31 August 2018
Early clinical PET imaging results with the novel PHF-tau radioligand [F-18]-T807.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777344
retrieved
31 August 2018
Tauopathy-like abnormalities and neurologic deficits in mice immunized with neuronal tau protein.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777344
retrieved
31 August 2018
Identifiers
DOI
10.1159/000440842
1 reference
stated in
Europe PubMed Central
PMCID
4777344
retrieved
4 September 2017
PMCID
4777344
1 reference
stated in
Europe PubMed Central
PMCID
4777344
retrieved
4 September 2017
PubMed ID
26551002
1 reference
stated in
Europe PubMed Central
PMCID
4777344
retrieved
4 September 2017
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