(Q38638219)

5 September 2017

title

Uromodulin: from physiology to rare and complex kidney disorders (English)

1 reference

5 September 2017

1

Olivier Devuyst

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author name string

Eric Olinger

series ordinal

2

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5 September 2017

Luca Rampoldi

series ordinal

3

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5 September 2017

language of work or name

English

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publication date

7 August 2017

1 reference

Nature Reviews Nephrology

5 September 2017

published in

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5 September 2017

volume

13

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5 September 2017

issue

9

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5 September 2017

page(s)

525-544

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https://scigraph.springernature.com/pub.10.1038/nrneph.2017.101

5 September 2017

exact match

0 references

cites work

Immunofluorescent localization of Tamm-Horsfall mucoprotein in human kidney

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https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

The nature of urinary casts

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Uromodulin: a unique 85-kilodalton immunosuppressive glycoprotein isolated from urine of pregnant women

21 January 2018

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Identification of human uromodulin as the Tamm-Horsfall urinary glycoprotein

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

The rediscovery of uromodulin (Tamm-Horsfall protein): from tubulointerstitial nephropathy to chronic kidney disease.

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Mutations of the UMOD gene are responsible for medullary cystic kidney disease 2 and familial juvenile hyperuricaemic nephropathy

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

A cluster of mutations in the UMOD gene causes familial juvenile hyperuricemic nephropathy with abnormal expression of uromodulin

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Multiple loci associated with indices of renal function and chronic kidney disease

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Common noncoding UMOD gene variants induce salt-sensitive hypertension and kidney damage by increasing uromodulin expression

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Common variants in UMOD associate with urinary uromodulin levels: a meta-analysis

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Uromodulin (Tamm-Horsfall glycoprotein): a renal ligand for lymphokines

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Nucleotide sequence and peptide motifs of mouse uromodulin (Tamm-Horsfall protein)--the most abundant protein in mammalian urine

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

A structured interdomain linker directs self-polymerization of human uromodulin

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

The ZP domain is a conserved module for polymerization of extracellular proteins

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

The turnover rate of rabbit urinary Tamm-Horsfall glycoprotein

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Tamm-Horsfall urinary glycoprotein. The chemical composition

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Bence Jones proteins bind to a common peptide segment of Tamm-Horsfall glycoprotein to promote heterotypic aggregation

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Intracellular transport, cell-surface exposure and release of recombinant Tamm-Horsfall glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Allelism of MCKD, FJHN and GCKD caused by impairment of uromodulin export dynamics

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Defective intracellular trafficking of uromodulin mutant isoforms

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Glycosylation sites and site-specific glycosylation in human Tamm-Horsfall glycoprotein

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Tamm-Horsfall glycoprotein: biology and clinical relevance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Pregnancy-associated changes in the glycosylation of tamm-horsfall glycoprotein. Expression of sialyl Lewis(x) sequences on core 2 type O-glycans derived from uromodulin.

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Functional rafts in cell membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Role of lipid rafts in membrane delivery of renal epithelial Na+-K+-ATPase, thick ascending limb

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

N-Glycans mediate the apical sorting of a GPI-anchored, raft-associated protein in Madin-Darby canine kidney cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Analysis of uromodulin polymerization provides new insights into the mechanisms regulating ZP domain-mediated protein assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Effects of freezing on the estimated amounts of Tamm--Horsfall glycoprotein in urine, as determined by radioimmunoassay

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Urinary uromodulin carries an intact ZP domain generated by a conserved C-terminal proteolytic cleavage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

The serine protease hepsin mediates urinary secretion and polymerisation of Zona Pellucida domain protein uromodulin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

The development of a radioimmunoassay for the measurement of urinary Tamm-Horsfall glycoprotein in the presence of sodium dodecyl sulphate

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Determination of uromodulin in human urine: influence of storage and processing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Analysis of Tamm-Horsfall protein by high-performance liquid chromatography with native fluorescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Genome-wide association study of blood pressure extremes identifies variant near UMOD associated with hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Selectively reduced expression of thick ascending limb Tamm-Horsfall protein in hypothyroid kidneys

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Proteomics. Tissue-based map of the human proteome

21 January 2018

2 references

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

21 January 2018

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

7 January 2021

inferred from DOI database lookup

Deep Sequencing in Microdissected Renal Tubules Identifies Nephron Segment-Specific Transcriptomes

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Atlas of gene expression in the mouse kidney: new features of glomerular parietal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Tamm-Horsfall protein-mRNA synthesis is localized to the thick ascending limb of Henle's loop in rat kidney

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Elucidation of the distal convoluted tubule transcriptome identifies new candidate genes involved in renal Mg(2+) handling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Tamm-Horsfall protein translocates to the basolateral domain of thick ascending limbs, interstitium, and circulation during recovery from acute kidney injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Tamm-Horsfall protein--uromodulin (1950-1990).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Atlas of gene expression in the developing kidney at microanatomic resolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Longitudinal patterns of urine biomarkers in infants across gestational ages

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Kidney-specific activity of the bovine uromodulin promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

The use of the uromodulin promoter to target production of recombinant proteins into urine of transgenic animals

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Thick ascending limb-specific expression of Cre recombinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

An intricate network of conserved DNA upstream motifs and associated transcription factors regulate the expression of uromodulin gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

A transcriptional network in polycystic kidney disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

The UCSC Genome Browser database: 2015 update

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Phylogeny of Tamm-Horsfall protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

GP-2/THP gene family encodes self-binding glycosylphosphatidylinositol-anchored proteins in apical secretory compartments of pancreas and kidney

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Phylogenetic, ontogenetic, and pathological aspects of the urine-concentrating mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Activation of the bumetanide-sensitive Na+,K+,2Cl- cotransporter (NKCC2) is facilitated by Tamm-Horsfall protein in a chloride-sensitive manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Tamm-Horsfall glycoprotein interacts with renal outer medullary potassium channel ROMK2 and regulates its function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Renal effects of Tamm-Horsfall protein (uromodulin) deficiency in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Validation of uromodulin as a candidate gene for human essential hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Pathophysiology-based treatment of idiopathic calcium kidney stones

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

N-Glycans carried by Tamm-Horsfall glycoprotein have a crucial role in the defense against urinary tract diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Progressive renal papillary calcification and ureteral stone formation in mice deficient for Tamm-Horsfall protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Tamm-Horsfall protein is a critical renal defense factor protecting against calcium oxalate crystal formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Idiopathic hypercalciuria and formation of calcium renal stones

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Uromodulin upregulates TRPV5 by impairing caveolin-mediated endocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Association of variants at UMOD with chronic kidney disease and kidney stones-role of age and comorbid diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Ablation of the Tamm-Horsfall protein gene increases susceptibility of mice to bladder colonization by type 1-fimbriated Escherichia coli.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Tamm-Horsfall protein knockout mice are more prone to urinary tract infection: rapid communication

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Tamm-Horsfall protein binds to type 1 fimbriated Escherichia coli and prevents E. coli from binding to uroplakin Ia and Ib receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Urinary Uromodulin and Risk of Urinary Tract Infections: The Cardiovascular Health Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

The Uromodulin Gene Locus Shows Evidence of Pathogen Adaptation through Human Evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Tamm-Horsfall glycoprotein binds IgG with high affinity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

The relationship of the influenza virus inhibitory activity of glycoproteins to their molecular size and sialic acid content

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Tamm-Horsfall protein-deficient thick ascending limbs promote injury to neighboring S3 segments in an MIP-2-dependent mechanism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Tamm-Horsfall protein protects the kidney from ischemic injury by decreasing inflammation and altering TLR4 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Tamm-Horsfall Protein Regulates Granulopoiesis and Systemic Neutrophil Homeostasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Tamm-Horsfall glycoprotein links innate immune cell activation with adaptive immunity via a Toll-like receptor-4-dependent mechanism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Uromodulin triggers IL-1β-dependent innate immunity via the NLRP3 inflammasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Tamm Horsfall protein binds to a single class of carbohydrate specific receptors on human neutrophils

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Uromodulin facilitates neutrophil migration across renal epithelial monolayers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Mechanisms of intranephronal proteinaceous cast formation by low molecular weight proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

The pathogenesis and diagnosis of acute kidney injury in multiple myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Mechanism and prevention of acute kidney injury from cast nephropathy in a rodent model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Pathobiology of cast nephropathy from human Bence Jones proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Localization of a single binding site for immunoglobulin light chains on human Tamm-Horsfall glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Mapping the binding domain of immunoglobulin light chains for Tamm-Horsfall protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Acute Kidney Injury Urine Biomarkers in Very Low-Birth-Weight Infants

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Early markers of Fabry disease revealed by proteomics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Identification of a unique urinary biomarker profile in patients with autosomal dominant polycystic kidney disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Associations of Urinary Uromodulin with Clinical Characteristics and Markers of Tubular Function in the General Population

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Clinical, Genetic, and Urinary Factors Associated with Uromodulin Excretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Functional genomic annotation of genetic risk loci highlights inflammation and epithelial biology networks in CKD

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Urinary uromodulin, kidney function, and cardiovascular disease in elderly adults

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Monitoring changes in gene expression in renal ischemia-reperfusion in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Association of Preoperative Urinary Uromodulin with AKI after Cardiac Surgery

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Comparison of urinary proteins in calcium stone formers and healthy individuals: a case-control study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Plasma Uromodulin Correlates With Kidney Function and Identifies Early Stages in Chronic Kidney Disease Patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Serum uromodulin predicts graft failure in renal transplant recipients

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Evidence for a role of uromodulin in chronic kidney disease progression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Tamm-Horsfall protein: are serum levels a marker for urinary tract obstruction?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Serum Uromodulin and Mortality Risk in Patients Undergoing Coronary Angiography

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Autoantibodies to Tamm-Horsfall protein, a tool for diagnosing the level of urinary-tract infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

The presence in serum of proteins which are immunologically cross-reactive with Tamm-Horsfall glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Mutations causing medullary cystic kidney disease type 1 lie in a large VNTR in MUC1 missed by massively parallel sequencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Atypical familial juvenile hyperuricemic nephropathy associated with a hepatocyte nuclear factor-1beta gene mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Dominant renin gene mutations associated with early-onset hyperuricemia, anemia, and chronic kidney failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Heterozygous Loss-of-Function SEC61A1 Mutations Cause Autosomal-Dominant Tubulo-Interstitial and Glomerulocystic Kidney Disease with Anemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Autosomal dominant tubulointerstitial kidney disease: diagnosis, classification, and management--A KDIGO consensus report

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Epidemiology of uromodulin-associated kidney disease - results from a nation-wide survey.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Phenotype and outcome in hereditary tubulointerstitial nephritis secondary to UMOD mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Association between genotype and phenotype in uromodulin-associated kidney disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Renal fibrosis is the common feature of autosomal dominant tubulointerstitial kidney diseases caused by mutations in mucin 1 or uromodulin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Alterations of uromodulin biology: a common denominator of the genetically heterogeneous FJHN/MCKD syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Uromodulin mutations causing familial juvenile hyperuricaemic nephropathy lead to protein maturation defects and retention in the endoplasmic reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

A transgenic mouse model for uromodulin-associated kidney diseases shows specific tubulo-interstitial damage, urinary concentrating defect and renal failure.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Novel missense mutation of uromodulin in mice causes renal dysfunction with alterations in urea handling, energy, and bone metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Standardized, systemic phenotypic analysis of Umod(C93F) and Umod(A227T) mutant mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Mitochondrial Dysregulation Secondary to Endoplasmic Reticulum Stress in Autosomal Dominant Tubulointerstitial Kidney Disease - UMOD (ADTKD-UMOD)

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

A mouse model for inherited renal fibrosis associated with endoplasmic reticulum stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Homozygosity for uromodulin disorders: FJHN and MCKD-type 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Mutant tamm-horsfall glycoprotein accumulation in endoplasmic reticulum induces apoptosis reversed by colchicine and sodium 4-phenylbutyrate

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

No amelioration of uromodulin maturation and trafficking defect by sodium 4-phenylbutyrate in vivo: studies in mouse models of uromodulin-associated kidney disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

A primary culture system of mouse thick ascending limb cells with preserved function and uromodulin processing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

New loci associated with kidney function and chronic kidney disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Genetic loci influencing kidney function and chronic kidney disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Genome-wide association and functional follow-up reveals new loci for kidney function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Rare mutations associating with serum creatinine and chronic kidney disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Genetic association for renal traits among participants of African ancestry reveals new loci for renal function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Association of eGFR-Related Loci Identified by GWAS with Incident CKD and ESRD.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Genome-wide association study of kidney function decline in individuals of European descent

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Investigation of known estimated glomerular filtration rate loci in patients with type 2 diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Association of kidney structure-related gene variants with type 2 diabetes-attributed end-stage kidney disease in African Americans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Biomarkers for incident CKD: a new framework for interpreting the literature

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Common genetic variants of the human uromodulin gene regulate transcription and predict plasma uric acid levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Insights into kidney diseases from genome-wide association studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Evolving importance of kidney disease: from subspecialty to global health burden

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Uromodulin levels associate with a common UMOD variant and risk for incident CKD.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

An evolutionary framework for common diseases: the ancestral-susceptibility model

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Association of trypanolytic ApoL1 variants with kidney disease in African Americans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Tamm-horsfall protein protects against urinary tract infection by proteus mirabilis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Renal calcinosis and stone formation in mice lacking osteopontin, Tamm-Horsfall protein, or both

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Tamm-Horsfall protein regulates circulating and renal cytokines by affecting glomerular filtration rate and acting as a urinary cytokine trap

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Type of uromodulin mutation and allelic status influence onset and severity of uromodulin-associated kidney disease in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Trans-ethnic Fine Mapping Highlights Kidney-Function Genes Linked to Salt Sensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Uromodulin, kidney function, cardiovascular disease, and mortality.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Finding the missing heritability of complex diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Epidermal growth factor-like modules

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Uromucoid (Tamm-Horsfall glycoprotein) forms different polymeric arrangements on a filter surface under different physicochemical conditions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Genome-wide study of familial juvenile hyperuricaemic (gouty) nephropathy (FJHN) indicates a new locus, FJHN3, linked to chromosome 2p22.1-p21

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Uromodulin gene variant is associated with type 2 diabetic nephropathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Unexpectedly high prevalence of rare genetic disorders in kidney transplant recipients with an unknown causal nephropathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Biosynthesis and oligosaccharide processing of human Tamm-Horsfall glycoprotein permanently expressed in HeLa cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Renal tubular interactions of proteins

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

A blood group Sda-active pentasaccharide isolated from Tamm-Horsfall urinary glycoprotein

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Mechanism of membrane anchoring affects polarized expression of two proteins in MDCK cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Molecular forms of human urinary mucoprotein present under physiological conditions

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Development and characterization of a pseudo multiple reaction monitoring method for the quantification of human uromodulin in urine

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Serum uromodulin-a marker of kidney function and renal parenchymal integrity.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Dietary salt regulates expression of Tamm-Horsfall glycoprotein in rats

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Urinary excretion rate of Tamm-Horsfall protein is related to salt intake in humans

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Localization of the Tamm-Horsfall glycoprotein (uromodulin) gene to chromosome 16p12.3-16p13.11

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Isolation of mouse THP gene promoter and demonstration of its kidney-specific activity in transgenic mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Localization of Tamm-Horsfall glycoprotein in the fetal and neonatal hamster kidney as demonstrated by immunofluorescence and immunoelectron microscopical techniques

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Tamm-Horsfall protein as a marker of tubular maturation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Distribution of immunoreactive Tamm-Horsfall protein in various species in the vertebrate classes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Effects of Tamm-Horsfall protein with normal and reduced sialic acid content upon the crystallization of calcium phosphate and calcium oxalate in human urine

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Effects of Tamm-Horsfall protein on polymorphonuclear leukocyte function

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Marked reduction of Tamm-Horsfall protein synthesis in hyperprostaglandin E-syndrome

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Human Tamm-Horsfall glycoprotein: urinary and plasma levels in normal subjects and patients with renal disease determined by a fully validated radioimmunoassay

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Increased excretions of beta2-microglobulin, IL-6, and IL-8 and decreased excretion of Tamm-Horsfall glycoprotein in urine of patients with active lupus nephritis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Tamm-Horsfall glycoprotein in streptozotocin diabetic rats: a study of kidney in situ hybridization, immunohistochemistry, and urinary excretion

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Tubular secretion of Tamm-Horsfall protein is decreased in type 1 (insulin-dependent) diabetic patients with diabetic nephropathy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Tamm-Horsfall protein excretion and its relation to citrate in urine of stone-forming patients

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Isoelectric focusing of native urinary uromodulin (Tamm-Horsfall protein) shows no physicochemical differences between stone formers and non-stone formers

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Serum Tamm-Horsfall protein levels in childhood: relationship with age and glomerular filtration rate

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Serum Tamm-Horsfall Glycoprotein Level in Children with Various Renal Diseases

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Antibody to Tamm-Horsfall protein in patients with urinary tract obstruction and vesicoureteral reflux

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Antibody to Tamm-Horsfall protein after acute tubular necrosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Serum antibody against Tamm-Horsfall protein in patients with renal cell carcinoma

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Tubulointerstitial immune complex nephritis in rats immunized with Tamm-Horsfall protein

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Autoantibodies to Tamm-Horsfall glycoprotein in children with renal damage associated with urinary tract infections

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Studies to assess the biological relevance of anti-Tamm-Horsfall protein antibodies detected by direct-binding enzyme-linked immunosorbent assay

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

A novel pattern of mutation in uromodulin disorders: autosomal dominant medullary cystic kidney disease type 2, familial juvenile hyperuricemic nephropathy, and autosomal dominant glomerulocystic kidney disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Uromodulin storage disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Mutations in the uromodulin gene decrease urinary excretion of Tamm-Horsfall protein

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

A novel homozygous UMOD mutation reveals gene dosage effects on uromodulin processing and urinary excretion

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Tamm-Horsfall protein knockout mice do not develop medullary cystic kidney disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Apoptosis induced by an uromodulin mutant C112Y and its suppression by topiroxostat

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Salt wasting and blood pressure

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.101

Tamm-Horsfall protein excretion during chronic alterations in urinary concentration and protein intake in the rat

31 March 2020

1 reference

12 December 2020

Uromodulin (Tamm-Horsfall glycoprotein/uromucoid) is a phosphatidylinositol-linked membrane protein

1 reference

12 December 2020

Natural autoantibodies against Tamm-Horsfall glycoprotein in normal individuals in relation to age and in adult patients with kidney diseases

1 reference

12 December 2020

Myeloma cast nephropathy: immunohistochemical and lectin studies.

1 reference

12 December 2020

Physiopathologic aspects of Tamm-Horsfall protein: a phylogenetically conserved marker of the thick ascending limb of Henle's loop

1 reference

12 December 2020

In vitro evidence that carbohydrate moieties derived from uromodulin, an 85,000 dalton immunosuppressive glycoprotein isolated from human pregnancy urine, are immunosuppressive in the absence of intact protein

1 reference

12 December 2020

Renal tubular immune complex formation in mice immunized with Tamm-Horsfall protein

1 reference

12 December 2020

Pronounced decrease of Tamm-Horsfall proteinuria in diabetics

1 reference

12 December 2020

Tamm-Horsfall uromucoprotein and the pathogenesis of casts, reflux nephropathy, and nephritides

1 reference

12 December 2020

Tubulointerstitial nephritis and immunologic responses to Tamm-Horsfall protein in rabbits challenged with homologous urine or Tamm-Horsfall protein

1 reference

12 December 2020

Excretion of Tamm-Horsfall glycoprotein in renal disease

1 reference

12 December 2020

Serum Tamm-Horsfall glycoprotein levels in health and in renal disease

1 reference

12 December 2020

Localization of Tamm-Horsfall glycoprotein in the human kidney using immuno-fluorescence and immuno-electron microscopical techniques

1 reference

12 December 2020

Tamm-Horsfall glycoprotein: role in inhibition and promotion of renal calcium oxalate stone formation studied with Fourier-transform infrared spectroscopy

1 reference

12 December 2020

Localization and regulation of the rat renal Na(+)-K(+)-2Cl- cotransporter, BSC-1

1 reference

12 December 2020

Characterization of Tamm-Horsfall protein in a rat nephrolithiasis model

1 reference

12 December 2020

Familial juvenile hyperuricemic nephropathy and autosomal dominant medullary cystic kidney disease type 2: two facets of the same disease?

1 reference

12 December 2020

Direct visualization of a mucoprotein component of urine

1 reference

12 December 2020

Characterization and separation of an inhibitor of viral hemagglutination present in urine.

1 reference

12 December 2020

The serum uromodulin level is associated with kidney function.

1 reference

12 December 2020

Serum uromodulin concentrations correlate with glomerular filtration rate in patients with chronic kidney disease

1 reference

12 December 2020

The Hypertension Pandemic: An Evolutionary Perspective

1 reference

12 December 2020

Identifiers

DOI

10.1038/NRNEPH.2017.101

1 reference

5 September 2017

1 reference