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Conformational and functional characterization of trapped complexes of the P-glycoprotein multidrug transporter.
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Europe PubMed Central
PMC publication ID
1609918
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16803457%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 December 2019
title
Conformational and functional characterization of trapped complexes of the P-glycoprotein multidrug transporter
(English)
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Europe PubMed Central
PMC publication ID
1609918
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16803457%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 December 2019
author
Frances J. Sharom
series ordinal
2
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Europe PubMed Central
PMC publication ID
1609918
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16803457%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 December 2019
author name string
Paula L Russell
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1
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Europe PubMed Central
PMC publication ID
1609918
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16803457%20AND%20SRC:MED&resulttype=core&format=json
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25 December 2019
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English
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publication date
1 October 2006
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PMC publication ID
1609918
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16803457%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 December 2019
published in
Biochemical Journal
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PMC publication ID
1609918
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16803457%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 December 2019
volume
399
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stated in
Europe PubMed Central
PMC publication ID
1609918
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16803457%20AND%20SRC:MED&resulttype=core&format=json
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25 December 2019
issue
2
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stated in
Europe PubMed Central
PMC publication ID
1609918
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16803457%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 December 2019
page(s)
315-323
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Europe PubMed Central
PMC publication ID
1609918
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16803457%20AND%20SRC:MED&resulttype=core&format=json
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25 December 2019
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Proximity of bound Hoechst 33342 to the ATPase catalytic sites places the drug binding site of P-glycoprotein within the cytoplasmic membrane leaflet
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FRET analysis indicates that the two ATPase active sites of the P-glycoprotein multidrug transporter are closely associated.
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Vanadate-induced trapping of nucleotides by purified maltose transport complex requires ATP hydrolysis
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AlF3 mimics the transition state of protein phosphorylation in the crystal structure of nucleoside diphosphate kinase and MgADP
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Peptides induce ATP hydrolysis at both subunits of the transporter associated with antigen processing
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Functionally similar vanadate-induced 8-azidoadenosine 5'-[alpha-(32)P]Diphosphate-trapped transition state intermediates of human P-glycoprotin are generated in the absence and presence of ATP hydrolysis
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25 September 2017
Drug-stimulated ATPase activity of human P-glycoprotein is blocked by disulfide cross-linking between the nucleotide-binding sites.
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25 September 2017
Human P-glycoprotein exhibits reduced affinity for substrates during a catalytic transition state
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25 September 2017
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25 September 2017
P-glycoprotein Is Stably Inhibited by Vanadate-induced Trapping of Nucleotide at a Single Catalytic Site
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25 September 2017
Characterization of the ATPase activity of P-glycoprotein from multidrug-resistant Chinese hamster ovary cells
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P-glycoprotein catalytic mechanism: studies of the ADP-vanadate inhibited state
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Stoichiometry and affinity of nucleotide binding to P-glycoprotein during the catalytic cycle
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31 August 2018
Nucleotide-induced conformational changes in P-glycoprotein and in nucleotide binding site mutants monitored by trypsin sensitivity.
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31 August 2018
Site-directed fluorescence labeling of P-glycoprotein on cysteine residues in the nucleotide binding domains.
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31 August 2018
Transmembrane aromatic amino acid distribution in P-glycoprotein. A functional role in broad substrate specificity.
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31 August 2018
Strategies for the purification of P-glycoprotein from multidrug-resistant Chinese hamster ovary cells
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31 August 2018
Both P-glycoprotein Nucleotide-binding Sites Are Catalytically Active
1 reference
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PubMed
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https://pubmed.ncbi.nlm.nih.gov/16803457
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Fluorescence studies on the nucleotide binding domains of the P-glycoprotein multidrug transporter
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/16803457
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Inhibition of P-glycoprotein ATPase activity by procedures involving trapping of nucleotide in catalytic sites
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/16803457
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Inhibition of P-glycoprotein ATPase activity by beryllium fluoride
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/16803457
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1042/BJ20060015
1 reference
stated in
Europe PubMed Central
PMC publication ID
1609918
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16803457%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 December 2019
PMC publication ID
1609918
1 reference
stated in
Europe PubMed Central
PMC publication ID
1609918
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16803457%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 December 2019
PubMed publication ID
16803457
1 reference
stated in
Europe PubMed Central
PMC publication ID
1609918
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16803457%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 December 2019
ResearchGate publication ID
6982162
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