(Q38683208)

5 September 2017

title

10 Genetic approaches to understanding the physiologic importance of the carboxyl methylation of isoprenylated proteins (English)

1 reference

5 September 2017

Steven G Clarke

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26718044%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Martin O Bergoc

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26718044%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Mark Phillips

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26718044%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

language of work or name

1 reference

1 January 2006

1 reference

5 September 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26718044%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

volume

24

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26718044%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

page(s)

273-301

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26718044%20AND%20SRC:MED&resulttype=core&format=json

Protein prenylation: molecular mechanisms and functional consequences

10 June 2020

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7 January 2021

Modulation of Ras and a-factor function by carboxyl-terminal proteolysis

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7 January 2021

CaaX converting enzymes

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7 January 2021

Mammalian prenylcysteine carboxyl methyltransferase is in the endoplasmic reticulum

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7 January 2021

A novel membrane-associated metalloprotease, Ste24p, is required for the first step of NH2-terminal processing of the yeast a-factor precursor

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7 January 2021

Dual roles for Ste24p in yeast a-factor maturation: NH2-terminal proteolysis and COOH-terminal CAAX processing

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7 January 2021

Signal transduction. How receptors turn Ras on.

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7 January 2021

Signal transduction. Why Ras needs Rho.

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7 January 2021

Disruption of the mouse Rce1 gene results in defective Ras processing and mislocalization of Ras within cells

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7 January 2021

Cloning and characterization of a mammalian prenyl protein-specific protease

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7 January 2021

Defective prelamin A processing and muscular and adipocyte alterations in Zmpste24 metalloproteinase-deficient mice.

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7 January 2021

Farnesyl cysteine C-terminal methyltransferase activity is dependent upon the STE14 gene product in Saccharomyces cerevisiae

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7 January 2021

The Saccharomyces cerevisiae prenylcysteine carboxyl methyltransferase Ste14p is in the endoplasmic reticulum membrane

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7 January 2021

Inhibition of membrane-associated methyltransferases by a cholesterol-based metal chelator

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7 January 2021

Protein carboxyl methylation in Saccharomyces cerevisiae: evidence for STE14-dependent and STE14-independent pathways

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7 January 2021

Functional inactivation of genes by dominant negative mutations

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7 January 2021

Nucleotide sequence of the yeast STE14 gene, which encodes farnesylcysteine carboxyl methyltransferase, and demonstration of its essential role in a-factor export

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7 January 2021

Fluorimetric evaluation of the affinities of isoprenylated peptides for lipid bilayers.

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7 January 2021

Isoprenylation/methylation of proteins enhances membrane association by a hydrophobic mechanism

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7 January 2021

The role of G protein methylation in the function of a geranylgeranylated beta gamma isoform

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7 January 2021

Significance of C-terminal cysteine modifications to the biological activity of the Saccharomyces cerevisiae a-factor mating pheromone

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7 January 2021

Role of carboxylmethylation in chemoattractant receptor-stimulated G protein activation and functional responses

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7 January 2021

Effect of gamma subunit carboxyl methylation on the interaction of G protein alpha subunits with beta gamma subunits of defined composition

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7 January 2021

Functional significance of G protein carboxymethylation

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7 January 2021

Phosducin and betagamma-transducin interaction I: effects of post-translational modifications

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7 January 2021

Identification of an isoprenylated cysteine methyl ester hydrolase activity in bovine rod outer segment membranes

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7 January 2021

Fractionation and characterization of protein C-terminal prenyl-cysteine methylesterase activities from rabbit brain

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7 January 2021

Carboxyl methylation of Ras-related proteins during signal transduction in neutrophils

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7 January 2021

Postprenylation CAAX processing is required for proper localization of Ras but not Rho GTPases

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7 January 2021

A polybasic domain or palmitoylation is required in addition to the CAAX motif to localize p21ras to the plasma membrane

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7 January 2021

Limited accumulation of damaged proteins in l-isoaspartyl (D-aspartyl) O-methyltransferase-deficient mice.

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7 January 2021

Novel methyltransferase activity modifying the carboxy terminal bis(geranylgeranyl)-Cys-Ala-Cys structure of small GTP-binding proteins

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7 January 2021

Targeted inactivation of the isoprenylcysteine carboxyl methyltransferase gene causes mislocalization of K-Ras in mammalian cells

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7 January 2021

Prenylcysteine carboxylmethyltransferase is essential for the earliest stages of liver development in mice

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7 January 2021

Absence of the CAAX endoprotease Rce1: effects on cell growth and transformation

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7 January 2021

Modification of eukaryotic signaling proteins by C-terminal methylation reactions

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7 January 2021

Prenylation-dependent association of Ki-Ras with microtubules. Evidence for a role in subcellular trafficking

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7 January 2021

The C-terminal polylysine region and methylation of K-Ras are critical for the interaction between K-Ras and microtubules

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7 January 2021

H-ras but not K-ras traffics to the plasma membrane through the exocytic pathway

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7 January 2021

Post-translational processing of RhoA. Carboxyl methylation of the carboxyl-terminal prenylcysteine increases the half-life of Rhoa

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7 January 2021

Signals from Ras and Rho GTPases interact to regulate expression of p21Waf1/Cip1.

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7 January 2021

Cross-talk between Ras and Rho signalling pathways in transformation favours proliferation and increased motility

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7 January 2021

Biochemical studies of Zmpste24-deficient mice

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7 January 2021

Isoprenylation is required for the processing of the lamin A precursor

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7 January 2021

In vitro assay and characterization of the farnesylation-dependent prelamin A endoprotease

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7 January 2021

Recurrent de novo point mutations in lamin A cause Hutchinson–Gilford progeria syndrome

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7 January 2021

Homozygous and compound heterozygous mutations in ZMPSTE24 cause the laminopathy restrictive dermopathy

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7 January 2021

A carboxyl-terminal interaction of lamin B1 is dependent on the CAAX endoprotease Rce1 and carboxymethylation

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7 January 2021

Post-prenylation-processing enzymes as new targets in oncogenesis

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7 January 2021

Targeting Ras and Rho GTPases as opportunities for cancer therapeutics

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7 January 2021

Automated identification of putative methyltransferases from genomic open reading frames

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7 January 2021

Carboxyl methylation of Ras regulates membrane targeting and effector engagement

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7 January 2021

Carboxyl methylation of Ras-related proteins

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7 January 2021

Farnesylcysteine analogues inhibit chemotactic peptide receptor-mediated G-protein activation in human HL-60 granulocyte membranes

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7 January 2021

Purification, functional reconstitution, and characterization of the Saccharomyces cerevisiae isoprenylcysteine carboxylmethyltransferase Ste14p

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7 January 2021

The carboxyl methyltransferase modifying G proteins is a metalloenzyme

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7 January 2021

Isoprenylcysteine carboxyl methyltransferase deficiency in mice

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7 January 2021

10.1016/S1874-6047(06)80012-0

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26718044%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

1 reference