(Q38703633)

5 September 2017

title

Targeting Epigenetic Mechanisms for Chronic Pain: A Valid Approach for the Development of Novel Therapeutics (English)

1 reference

Beverley Greenwood-Van Meerveld

5 September 2017

0 references

series ordinal

3

object named as

Beverley Greenwood-Van Meerveld

1 reference

5 September 2017

Casey O Ligon

1

1 reference

5 September 2017

Rachel D Moloney

series ordinal

2

1 reference

5 September 2017

language of work or name

English

0 references

publication date

19 January 2016

1 reference

Journal of Pharmacology and Experimental Therapeutics

5 September 2017

published in

1 reference

5 September 2017

volume

357

1 reference

5 September 2017

issue

1

1 reference

5 September 2017

page(s)

84-93

1 reference

Afferent pain pathways: a neuroanatomical review

5 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1124%2FJPET.115.231670

Inhibition of Class II Histone Deacetylases in the Spinal Cord Attenuates Inflammatory Hyperalgesia

21 January 2018

1 reference

https://api.crossref.org/works/10.1124%2FJPET.115.231670

21 January 2018

The mammalian epigenome

1 reference

https://api.crossref.org/works/10.1124%2FJPET.115.231670

21 January 2018

The neurobiology of pain

1 reference

https://api.crossref.org/works/10.1124%2FJPET.115.231670

Regulation of transcription by long noncoding RNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1124%2FJPET.115.231670

Survey of chronic pain in Europe: Prevalence, impact on daily life, and treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1124%2FJPET.115.231670

Epigenetics and the transition from acute to chronic pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1124%2FJPET.115.231670

Intestinal barrier function in health and gastrointestinal disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1124%2FJPET.115.231670

Epigenetic upregulation of metabotropic glutamate receptor 2 in the spinal cord attenuates oestrogen-induced visceral hypersensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1124%2FJPET.115.231670

Gray matter alterations in chronic pain: A network-oriented meta-analytic approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1124%2FJPET.115.231670

Visceral Pain: Mechanisms of Peripheral and Central Sensitization

21 January 2018

1 reference

https://api.crossref.org/works/10.1124%2FJPET.115.231670

DNA methylation and demethylation in mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1124%2FJPET.115.231670

Erasing the methyl mark: histone demethylases at the center of cellular differentiation and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1124%2FJPET.115.231670

Protein methyltransferases as a target class for drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1124%2FJPET.115.231670

HDAC4 is required for inflammation-associated thermal hypersensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1124%2FJPET.115.231670

Colocalized structural and functional changes in the cortex of patients with trigeminal neuropathic pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1124%2FJPET.115.231670

Opioids for chronic pain: new evidence, new strategies, safe prescribing

21 January 2018

1 reference

https://api.crossref.org/works/10.1124%2FJPET.115.231670

HDAC inhibitors attenuate the development of hypersensitivity in models of neuropathic pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1124%2FJPET.115.231670

Chronic opioid use is associated with increased DNA methylation correlating with increased clinical pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1124%2FJPET.115.231670

Diffusion tensor imaging detects microstructural reorganization in the brain associated with chronic irritable bowel syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1124%2FJPET.115.231670

An integrated encyclopedia of DNA elements in the human genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1124%2FJPET.115.231670

The widespread impact of mammalian MicroRNAs on mRNA repression and evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1124%2FJPET.115.231670

Bidirectional integrative regulation of Cav1.2 calcium channel by microRNA miR-103: role in pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1124%2FJPET.115.231670

Elevated circulating miR-150 and miR-342-3p in patients with irritable bowel syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1124%2FJPET.115.231670

Regulation of gene expression and pain states by epigenetic mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1124%2FJPET.115.231670

Pain as a global public health priority

21 January 2018

1 reference

https://api.crossref.org/works/10.1124%2FJPET.115.231670

Epigenetic regulation of gene expression in physiological and pathological brain processes

21 January 2018

1 reference

https://api.crossref.org/works/10.1124%2FJPET.115.231670

The modern pharmacology of paracetamol: therapeutic actions, mechanism of action, metabolism, toxicity and recent pharmacological findings

21 January 2018

1 reference

https://api.crossref.org/works/10.1124%2FJPET.115.231670

Altered viscerotopic cortical innervation in patients with irritable bowel syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1124%2FJPET.115.231670

Chatting histone modifications in mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1124%2FJPET.115.231670

Acetaminophen-induced Liver Injury: from Animal Models to Humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1124%2FJPET.115.231670

Stress-induced pain: a target for the development of novel therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1124%2FJPET.115.231670

Role of BDNF epigenetics in activity-dependent neuronal plasticity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1124%2FJPET.115.231670

Epigenetic upregulation of CCL2 and CCL3 via histone modifications in infiltrating macrophages after peripheral nerve injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1124%2FJPET.115.231670

Central mechanisms of pathological pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1124%2FJPET.115.231670

G9a is essential for epigenetic silencing of K(+) channel genes in acute-to-chronic pain transition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1124%2FJPET.115.231670

MicroRNA-146a-5p attenuates neuropathic pain via suppressing TRAF6 signaling in the spinal cord

21 January 2018

1 reference

https://api.crossref.org/works/10.1124%2FJPET.115.231670

Synaptic plasticity in pathological pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1124%2FJPET.115.231670

Brain white matter structural properties predict transition to chronic pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1124%2FJPET.115.231670

HDAC inhibitors restore C-fibre sensitivity in experimental neuropathic pain model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1124%2FJPET.115.231670

Early-life stress-induced visceral hypersensitivity and anxiety behavior is reversed by histone deacetylase inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1124%2FJPET.115.231670

HDAC inhibitor-based therapies: can we interpret the code?

21 January 2018

1 reference

https://api.crossref.org/works/10.1124%2FJPET.115.231670

Dynamic protein methylation in chromatin biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1124%2FJPET.115.231670

Epigenetic modification of spinal miR-219 expression regulates chronic inflammation pain by targeting CaMKIIγ.

21 January 2018

1 reference

https://api.crossref.org/works/10.1124%2FJPET.115.231670

Mix and match: heterodimers and opioid tolerance

21 January 2018

1 reference

https://api.crossref.org/works/10.1124%2FJPET.115.231670

Promoter demethylation of cystathionine-β-synthetase gene contributes to inflammatory pain in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1124%2FJPET.115.231670

Critical role of nociceptor plasticity in chronic pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1124%2FJPET.115.231670

Emerging roles of microRNAs in chronic pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1124%2FJPET.115.231670

MicroRNA-mediated GABA Aα-1 receptor subunit down-regulation in adult spinal cord following neonatal cystitis-induced chronic visceral pain in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1124%2FJPET.115.231670

DNA methylation: roles in mammalian development

21 January 2018

1 reference

https://api.crossref.org/works/10.1124%2FJPET.115.231670

miR-203 regulates nociceptive sensitization after incision by controlling phospholipase A2 activating protein expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1124%2FJPET.115.231670

DNA methylation of SPARC and chronic low back pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1124%2FJPET.115.231670

Persistent inflammation-induced up-regulation of brain-derived neurotrophic factor (BDNF) promotes synaptic delivery of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor GluA1 subunits in descending pain modulatory circuits

21 January 2018

1 reference

https://api.crossref.org/works/10.1124%2FJPET.115.231670

Importance of epigenetic mechanisms in visceral pain induced by chronic water avoidance stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1124%2FJPET.115.231670

Common chronic pain conditions in developed and developing countries: gender and age differences and comorbidity with depression-anxiety disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1124%2FJPET.115.231670

Intrathecal 5-azacytidine inhibits global DNA methylation and methyl- CpG-binding protein 2 expression and alleviates neuropathic pain in rats following chronic constriction injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1124%2FJPET.115.231670

The balancing act: endogenous modulation of pain in functional gastrointestinal disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1124%2FJPET.115.231670

MicroRNA-124 as a novel treatment for persistent hyperalgesia

21 January 2018

1 reference

https://api.crossref.org/works/10.1124%2FJPET.115.231670

Central sensitization: implications for the diagnosis and treatment of pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1124%2FJPET.115.231670

Neuronal plasticity: increasing the gain in pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1124%2FJPET.115.231670

Aberrant methylation at HOXA10 may be responsible for its aberrant expression in the endometrium of patients with endometriosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1124%2FJPET.115.231670

Promoter hypermethylation of progesterone receptor isoform B (PR-B) in endometriosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1124%2FJPET.115.231670

Valproate prevents dysregulation of spinal glutamate and reduces the development of hypersensitivity in rats after peripheral nerve injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1124%2FJPET.115.231670

Transposable elements in the mammalian germline: a comfortable niche or a deadly trap?

21 January 2018

1 reference

https://api.crossref.org/works/10.1124%2FJPET.115.231670

Role of MicroRNA in Visceral Pain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1124%2FJPET.115.231670

Epigenetic suppression of GAD65 expression mediates persistent pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1124%2FJPET.115.231670

MeCP2 repression of G9a in regulation of pain and morphine reward

21 January 2018

1 reference

https://api.crossref.org/works/10.1124%2FJPET.115.231670

A long noncoding RNA contributes to neuropathic pain by silencing Kcna2 in primary afferent neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1124%2FJPET.115.231670

New insights into visceral hypersensitivity--clinical implications in IBS

21 January 2018

1 reference

https://api.crossref.org/works/10.1124%2FJPET.115.231670

Intestinal membrane permeability and hypersensitivity in the irritable bowel syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1124%2FJPET.115.231670

Curcumin alleviates neuropathic pain by inhibiting p300/CBP histone acetyltransferase activity-regulated expression of BDNF and cox-2 in a rat model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1124%2FJPET.115.231670

p300 exerts an epigenetic role in chronic neuropathic pain through its acetyltransferase activity in rats following chronic constriction injury (CCI).

21 January 2018

1 reference

https://api.crossref.org/works/10.1124%2FJPET.115.231670

CANALIZATION OF DEVELOPMENT AND THE INHERITANCE OF ACQUIRED CHARACTERS

21 January 2018

1 reference

https://api.crossref.org/works/10.1124%2FJPET.115.231670

21 January 2018

Identifiers

DOI

10.1124/JPET.115.231670

1 reference

5 September 2017

1 reference