(Q38725573)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27989769%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

title

Adaptive Chromatin Remodeling Drives Glioblastoma Stem Cell Plasticity and Drug Tolerance (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27989769%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

1 reference

15

1 reference

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30 March 2020

Shawn M. Gillespie

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27989769%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

Tyler Miller

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27989769%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

Peter van Galen

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27989769%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

16

Jeremy N Rich

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27989769%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

20

Bradley E Bernstein

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27989769%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

author name string

Brian B Liau

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27989769%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

Cem Sievers

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27989769%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

Laura K Donohue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27989769%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

William A Flavahan

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27989769%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

Andrew S Venteicher

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27989769%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

Christine H Hebert

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27989769%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

Christopher D Carey

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27989769%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

Scott J Rodig

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27989769%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

Sarah J Shareef

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27989769%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

Fadi J Najm

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27989769%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

Hiroaki Wakimoto

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27989769%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

Jon C Aster

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27989769%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

Mario L Suvà

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27989769%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

Anoop P Patel

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27989769%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

language of work or name

English

0 references

publication date

15 December 2016

1 reference

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30 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27989769%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

volume

20

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27989769%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27989769%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

page(s)

233-246.e7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27989769%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

30 March 2020

1 reference

10 June 2022

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pmc&rettype=xml&id=5291795

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NOTCH blockade combined with radiation therapy and temozolomide prolongs survival of orthotopic glioblastoma.

23 June 2018

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23 June 2018

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23 June 2018

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PDGF receptor alpha inhibition induces apoptosis in glioblastoma cancer stem cells refractory to anti-Notch and anti-EGFR treatment.

23 June 2018

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Inhibition of demethylases by GSK-J1/J4.

23 June 2018

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Rational design of highly active sgRNAs for CRISPR-Cas9-mediated gene inactivation.

23 June 2018

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Molecular heterogeneity of glioblastoma and its clinical relevance

23 June 2018

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Contrasting roles of histone 3 lysine 27 demethylases in acute lymphoblastic leukaemia

23 June 2018

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Mechanisms of disseminated cancer cell dormancy: an awakening field

23 June 2018

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Quiescent sox2(+) cells drive hierarchical growth and relapse in sonic hedgehog subgroup medulloblastoma

23 June 2018

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Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma

23 June 2018

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Cancer epigenetics: tumor heterogeneity, plasticity of stem-like states, and drug resistance.

23 June 2018

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Prospective identification and purification of quiescent adult neural stem cells from their in vivo niche

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5291795

The histone lysine demethylase JMJD3/KDM6B is recruited to p53 bound promoters and enhancer elements in a p53 dependent manner

23 June 2018

1 reference

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ngs.plot: Quick mining and visualization of next-generation sequencing data by integrating genomic databases

23 June 2018

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Reconstructing and reprogramming the tumor-propagating potential of glioblastoma stem-like cells

23 June 2018

1 reference

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An epigenetic mechanism of resistance to targeted therapy in T cell acute lymphoblastic leukemia

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5291795

Full-length RNA-seq from single cells using Smart-seq2.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5291795

Targeted therapy resistance mediated by dynamic regulation of extrachromosomal mutant EGFR DNA.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5291795

The somatic genomic landscape of glioblastoma

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5291795

Epigenomic enhancer annotation reveals a key role for NFIX in neural stem cell quiescence

23 June 2018

1 reference

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Software for computing and annotating genomic ranges

23 June 2018

1 reference

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Overcoming intrinsic multidrug resistance in melanoma by blocking the mitochondrial respiratory chain of slow-cycling JARID1B(high) cells

23 June 2018

1 reference

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The Genotype-Tissue Expression (GTEx) project

23 June 2018

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Occupying Chromatin: Polycomb Mechanisms for Getting to Genomic Targets, Stopping Transcriptional Traffic, and Staying Put

23 June 2018

1 reference

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Genome-wide chromatin state transitions associated with developmental and environmental cues

23 June 2018

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Histone demethylase Jumonji D3 (JMJD3) as a tumor suppressor by regulating p53 protein nuclear stabilization

23 June 2018

1 reference

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Diagnostic and therapeutic avenues for glioblastoma: no longer a dead end?

23 June 2018

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An integrated encyclopedia of DNA elements in the human genome

23 June 2018

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A restricted cell population propagates glioblastoma growth after chemotherapy

23 June 2018

1 reference

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A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response

23 June 2018

1 reference

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Heterodimeric JAK-STAT activation as a mechanism of persistence to JAK2 inhibitor therapy

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5291795

RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5291795

Genome-wide analysis reveals conserved and divergent features of Notch1/RBPJ binding in human and murine T-lymphoblastic leukemia cells

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5291795

The role of Notch signaling in adult neurogenesis

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5291795

The central nervous system-restricted transcription factor Olig2 opposes p53 responses to genotoxic damage in neural progenitors and malignant glioma

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5291795

Differential expression analysis for sequence count data

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5291795

Notch and EGFR pathway interaction regulates neural stem cell number and self-renewal

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5291795

Mechanistic insights into Notch receptor signaling from structural and biochemical studies

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5291795

Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5291795

A temporarily distinct subpopulation of slow-cycling melanoma cells is required for continuous tumor growth

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5291795

ChIPpeakAnno: a Bioconductor package to annotate ChIP-seq and ChIP-chip data

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5291795

A chromatin-mediated reversible drug-tolerant state in cancer cell subpopulations

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5291795

Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5291795

FoxOs cooperatively regulate diverse pathways governing neural stem cell homeostasis

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5291795

FoxO3 regulates neural stem cell homeostasis

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5291795

The H3K27me3 demethylase JMJD3 contributes to the activation of the INK4A-ARF locus in response to oncogene- and stress-induced senescence

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5291795

Fast and accurate short read alignment with Burrows-Wheeler transform

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5291795

SSEA-1 is an enrichment marker for tumor-initiating cells in human glioblastoma

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5291795

The canonical Notch signaling pathway: unfolding the activation mechanism

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5291795

Human glioblastoma-derived cancer stem cells: establishment of invasive glioma models and treatment with oncolytic herpes simplex virus vectors

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5291795

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5291795

Integrative analysis of HIF binding and transactivation reveals its role in maintaining histone methylation homeostasis

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5291795

Activity of dasatinib, a dual SRC/ABL kinase inhibitor, and IPI-504, a heat shock protein 90 inhibitor, against gastrointestinal stromal tumor-associated PDGFRAD842V mutation.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5291795

A role for the transcription factor HEY1 in glioblastoma

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5291795

The histone H3 lysine-27 demethylase Jmjd3 links inflammation to inhibition of polycomb-mediated gene silencing

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5291795

Glioma stem cells promote radioresistance by preferential activation of the DNA damage response

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5291795

Tumor stem cells derived from glioblastomas cultured in bFGF and EGF more closely mirror the phenotype and genotype of primary tumors than do serum-cultured cell lines

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5291795

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5291795

Identification of human brain tumour initiating cells

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5291795

Cooperative transcriptional activation by the neurogenic basic helix-loop-helix protein MASH1 and members of the myocyte enhancer factor-2 (MEF2) family

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5291795

Expansion of CD133-positive glioma cells in recurrent de novo glioblastomas after radiotherapy and chemotherapy.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5291795

An aberrant transcription factor network essential for Wnt signaling and stem cell maintenance in glioblastoma.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5291795

Essential roles of Notch signaling in maintenance of neural stem cells in developing and adult brains.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5291795

Autocrine TGF-beta signaling maintains tumorigenicity of glioma-initiating cells through Sry-related HMG-box factors.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5291795

SOX2 silencing in glioblastoma tumor-initiating cells causes stop of proliferation and loss of tumorigenicity.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5291795

Differential Notch signalling distinguishes neural stem cells from intermediate progenitors.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5291795

Mastermind critically regulates Notch-mediated lymphoid cell fate decisions.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5291795

10.1016/J.STEM.2016.11.003

31 August 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27989769%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27989769%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

PubMed publication ID

27989769

1 reference