(Q38763707)

6 September 2017

Platelet-derived sphingosine-1-phosphate and inflammation: from basic mechanisms to clinical implications (English)

1 reference

6 September 2017

Stefania Elena Navone

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26950429%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Giovanni Marfia

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26950429%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Rolando Campanella

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26950429%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Laura Riboni

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26950429%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

author name string

Clara Di Vito

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26950429%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Loubna Abdel Hadi

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26950429%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Maria Elisa Mancuso

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26950429%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

publication date

7 March 2016

1 reference

6 September 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26950429%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

volume

27

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26950429%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

issue

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26950429%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

page(s)

393-401

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26950429%20AND%20SRC:MED&resulttype=core&format=json

The incredible journey: From megakaryocyte development to platelet formation.

1 June 2020

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21 January 2018

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Role of sphingosine kinases and lipid phosphate phosphatases in regulating spatial sphingosine 1-phosphate signalling in health and disease

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Principles of bioactive lipid signalling: lessons from sphingolipids

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"Inside-out" signaling of sphingosine-1-phosphate: therapeutic targets

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21 January 2018

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Emerging biology of sphingosine-1-phosphate: its role in pathogenesis and therapy

21 January 2018

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Sphingosine 1-phosphate lyase, a key regulator of sphingosine 1-phosphate signaling and function

21 January 2018

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Sphingosine-1-phosphate phosphatases

21 January 2018

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Lipid phosphate phosphatases and their roles in mammalian physiology and pathology

21 January 2018

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Sources, metabolism, and regulation of circulating sphingosine-1-phosphate

21 January 2018

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Endothelium-protective sphingosine-1-phosphate provided by HDL-associated apolipoprotein M

21 January 2018

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Interaction of sphingosine 1-phosphate with plasma components, including lipoproteins, regulates the lipid receptor-mediated actions

21 January 2018

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Plasma lipoproteins behave as carriers of extracellular sphingosine 1-phosphate: is this an atherogenic mediator or an anti-atherogenic mediator?

21 January 2018

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Erythrocytes store and release sphingosine 1-phosphate in blood.

21 January 2018

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Vascular endothelium as a contributor of plasma sphingosine 1-phosphate

21 January 2018

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Plasma sphingosine-1-phosphate measurement in healthy subjects: close correlation with red blood cell parameters.

21 January 2018

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The sphingosine-1-phosphate transporter Spns2 expressed on endothelial cells regulates lymphocyte trafficking in mice

21 January 2018

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Sphingosine kinase 2 (Sphk2) regulates platelet biogenesis by providing intracellular sphingosine 1-phosphate (S1P).

21 January 2018

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A novel role of sphingosine 1-phosphate receptor S1pr1 in mouse thrombopoiesis

21 January 2018

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S1P and the birth of platelets.

21 January 2018

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Shaping of terminal megakaryocyte differentiation and proplatelet development by sphingosine-1-phosphate receptor S1P4.

21 January 2018

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Sphingosine 1-phosphate as a link between blood coagulation and inflammation

21 January 2018

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Sphingosine 1-phosphate in coagulation and inflammation.

21 January 2018

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The S1P(2) receptor expressed in human platelets is linked to the RhoA-Rho kinase pathway and is down regulated in type 2 diabetes.

21 January 2018

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Phospholipids released from activated platelets improve platelet aggregation and endothelial cell migration

21 January 2018

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Sphingosine 1-Phosphate Produced by Sphingosine Kinase 2 Intrinsically Controls Platelet Aggregation In Vitro and In Vivo.

21 January 2018

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21 January 2018

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21 January 2018

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Zn2+-stimulated sphingomyelinase is secreted by many cell types and is a product of the acid sphingomyelinase gene

21 January 2018

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Neutral/alkaline and acid ceramidase activities are actively released by murine endothelial cells.

21 January 2018

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Transfer of phosphatidylcholine, phosphatidylethanolamine and sphingomyelin from low- and high-density lipoprotein to human platelets

21 January 2018

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21 January 2018

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Evidence for the presence of multiple forms of Sph kinase in human platelets

21 January 2018

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Sphingosine 1-phosphate is released from the cytosol of rat platelets in a carrier-mediated manner

21 January 2018

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Granule-mediated release of sphingosine-1-phosphate by activated platelets

21 January 2018

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Lipid phosphate phosphatases regulate lysophosphatidic acid production and signaling in platelets: studies using chemical inhibitors of lipid phosphate phosphatase activity

21 January 2018

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Sphingosine 1-phosphate release from platelets during clot formation: close correlation between platelet count and serum sphingosine 1-phosphate concentration

21 January 2018

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Multiple mechanisms linked to platelet activation result in lysophosphatidic acid and sphingosine 1-phosphate generation in blood.

21 January 2018

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The immunomodulator FTY720 is phosphorylated and released from platelets

21 January 2018

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Quantification of sphingosine 1-phosphate by validated LC-MS/MS method revealing strong correlation with apolipoprotein M in plasma but not in serum due to platelet activation during blood coagulation

21 January 2018

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Sphingosine 1-phosphate-related metabolism in the blood vessel.

21 January 2018

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Sphingosine 1-phosphate (S1P) carrier-dependent regulation of endothelial barrier: high density lipoprotein (HDL)-S1P prolongs endothelial barrier enhancement as compared with albumin-S1P via effects on levels, trafficking, and signaling of S1P1.

21 January 2018

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Sphingolipid metabolites in inflammatory disease

21 January 2018

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21 January 2018

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Acute systemic inflammation up-regulates secretory sphingomyelinase in vivo: a possible link between inflammatory cytokines and atherogenesis

21 January 2018

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Secretory sphingomyelinase in health and disease.

21 January 2018

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Conformational changes of apoB-100 in SMase-modified LDL mediate formation of large aggregates at acidic pH.

21 January 2018

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Platelet protease-activated receptor (PAR)4, but not PAR1, associated with neutral sphingomyelinase responsible for thrombin-stimulated ceramide-NF-κB signaling in human platelets

21 January 2018

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Platelet-derived microvesicles induce differential gene expression in monocytic cells: a DNA microarray study

21 January 2018

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Signaling of sphingosine-1-phosphate via the S1P/EDG-family of G-protein-coupled receptors

21 January 2018

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Endothelial functions of sphingosine-1-phosphate

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Sphingosine 1-phosphate promotes endothelial cell barrier integrity by Edg-dependent cytoskeletal rearrangement

21 January 2018

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Role of sphingosine-1 phosphate in the enhancement of endothelial barrier integrity by platelet-released products

21 January 2018

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Platelet-released phospholipids link haemostasis and angiogenesis

21 January 2018

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The functional role of platelets in the regulation of angiogenesis

21 January 2018

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Platelet-derived sphingosine 1-phosphate induces migration of Jurkat T cells.

21 January 2018

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Sphingosine 1-phosphate enhances Fc gamma receptor-mediated neutrophil activation and recruitment under flow conditions.

21 January 2018

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Sphingosine-1-phosphate induces thrombin receptor PAR-4 expression to enhance cell migration and COX-2 formation in human monocytes.

21 January 2018

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Platelets in inflammation and atherogenesis

21 January 2018

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Sphingosine 1-phosphate: a regulator of arterial lesions

21 January 2018

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Atheroprotective role of high-density lipoprotein (HDL)-associated sphingosine-1-phosphate (S1P)

21 January 2018

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Expression of adhesion molecules by sphingosine 1-phosphate and histamine in endothelial cells.

21 January 2018

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HDL-bound sphingosine 1-phosphate acts as a biased agonist for the endothelial cell receptor S1P1 to limit vascular inflammation

21 January 2018

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Predicting obstructive coronary artery disease with serum sphingosine-1-phosphate

21 January 2018

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Enhanced release of sphingosine-1-phosphate from hypercholesterolemic platelets: role in development of hypercholesterolemic atherosclerosis

21 January 2018

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Acid sphingomyelinase regulates platelet cell membrane scrambling, secretion, and thrombus formation

21 January 2018

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Platelet-derived sphingosine 1-phosphate induces contraction of coronary artery smooth muscle cells via S1P2.

21 January 2018

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FTY720, a synthetic sphingosine 1 phosphate analogue, inhibits development of atherosclerosis in low-density lipoprotein receptor-deficient mice.

21 January 2018

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The sphingosine-1-phosphate analogue FTY720 reduces atherosclerosis in apolipoprotein E-deficient mice.

21 January 2018

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Systemic sclerosis: a prototypic multisystem fibrotic disorder

21 January 2018

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Pathogenesis of Systemic Sclerosis

21 January 2018

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Understanding fibrosis in systemic sclerosis: shifting paradigms, emerging opportunities

21 January 2018

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Oxidative stress elicits platelet/leukocyte inflammatory interactions via HMGB1: a candidate for microvessel injury in sytemic sclerosis

21 January 2018

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Platelet contributions to the pathogenesis of systemic sclerosis

21 January 2018

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The role of platelets in the pathogenesis of systemic sclerosis

21 January 2018

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Elevated serum levels of arachidonoyl-lysophosphatidic acid and sphingosine 1-phosphate in systemic sclerosis

21 January 2018

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Pathogenesis of glomerular damage in glomerulonephritis

21 January 2018

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Platelet-derived growth factor: a potentially important cytokine in glomerular disease

21 January 2018

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Platelets are relevant mediators of renal injury induced by primary endothelial lesions

21 January 2018

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Sphingosine 1-phosphate in renal diseases

21 January 2018

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Targeting the sphingosine kinase/sphingosine 1-phosphate pathway to treat chronic inflammatory kidney diseases

21 January 2018

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Sphingosine 1-phosphate stimulates rat mesangial cell proliferation from outside the cells

21 January 2018

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Platelets mediate neutrophil-dependent immune complex nephritis in the rat

21 January 2018

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N,N-dimethylsphingosine inhibition of sphingosine kinase and sphingosine 1-phosphate activity in human platelets

21 January 2018

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Sphingolipids as bioactive regulators of thrombin generation

21 January 2018

1 reference

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S1P modulator FTY720 limits matrix expansion in acute anti-thy1 mesangioproliferative glomerulonephritis.

21 January 2018

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Fingolimod (FTY720): discovery and development of an oral drug to treat multiple sclerosis

21 January 2018

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10.3109/09537104.2016.1144179

21 January 2018

Identifiers

DOI

1 reference

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1 June 2020

1 reference