(Q38769887)

15 June 2018

title

Limited heterogeneity of known driver gene mutations among the metastases of individual patients with pancreatic cancer (English)

1 reference

15 June 2018

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3

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15 June 2018

Benjamin Allen

5

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15 June 2018

Zachary A Kohutek

Zachary A Kohutek

10

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Kenneth W. Kinzler

18

Kenneth W Kinzler

1 reference

15 June 2018

Christine A Iacobuzio-Donahue

20

Christine A Iacobuzio-Donahue

1 reference

15 June 2018

Ralph H. Hruban

15

Ralph H Hruban

1 reference

15 June 2018

Martin A. Nowak

16

Martin A Nowak

1 reference

15 June 2018

Alvin P Makohon-Moore

1

Alvin P Makohon-Moore

1 reference

15 June 2018

Marc A Attiyeh

12

Marc Attiyeh

1 reference

15 June 2018

Laura D Wood

14

Laura D Wood

1 reference

15 June 2018

Jungeui Hong

11

Jungeui Hong

1 reference

15 June 2018

Fay Wong

8

Fay Wong

1 reference

15 June 2018

Nickolas Papadopoulos

17

Nickolas Papadopoulos

1 reference

15 June 2018

Krishnendu Chatterjee

7

Krishnendu Chatterjee

1 reference

15 June 2018

Ivana Bozic

4

Ivana Bozic

1 reference

15 June 2018

Yuchen Jiao

9

Yuchen Jiao

1 reference

15 June 2018

author name string

Ming Zhang

2

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15 June 2018

Deepanjan Kundu

6

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15 June 2018

Breanna Javier

13

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15 June 2018

language of work or name

English

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publication date

16 January 2017

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15 June 2018

published in

Nature Genetics

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15 June 2018

volume

49

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15 June 2018

issue

3

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15 June 2018

page(s)

358-366

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15 June 2018

Tissue-specific mutation accumulation in human adult stem cells during life

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23 June 2018

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The genomic landscape and evolution of endometrial carcinoma progression and abdominopelvic metastasis

23 June 2018

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Substantial interindividual and limited intraindividual genomic diversity among tumors from men with metastatic prostate cancer

23 June 2018

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Genomic analyses identify molecular subtypes of pancreatic cancer

23 June 2018

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Quantifying Clonal and Subclonal Passenger Mutations in Cancer Evolution

23 June 2018

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23 June 2018

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Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity

23 June 2018

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Adenosquamous carcinoma of the pancreas: Molecular characterization of 23 patients along with a literature review

23 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5663439

A spatial model predicts that dispersal and cell turnover limit intratumour heterogeneity

23 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5663439

Phylogenetic analyses of melanoma reveal complex patterns of metastatic dissemination.

23 June 2018

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Toward understanding and exploiting tumor heterogeneity

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5663439

Pancreatic Cancer Metastases Harbor Evidence of Polyclonality

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5663439

Subclonal diversification of primary breast cancer revealed by multiregion sequencing

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5663439

Reconstruction of clonal trees and tumor composition from multi-sample sequencing data

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5663439

Fast and scalable inference of multi-sample cancer lineages

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5663439

Whole-exome sequencing of pancreatic cancer defines genetic diversity and therapeutic targets

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5663439

The evolutionary history of lethal metastatic prostate cancer

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5663439

Tracking the origins and drivers of subclonal metastatic expansion in prostate cancer.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5663439

Whole genomes redefine the mutational landscape of pancreatic cancer

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5663439

A Big Bang model of human colorectal tumor growth

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5663439

Spatial and temporal diversity in genomic instability processes defines lung cancer evolution

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5663439

Genomic architecture and evolution of clear cell renal cell carcinomas defined by multiregion sequencing

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5663439

Genomic and transcriptomic plasticity in treatment-naive ovarian cancer

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5663439

Inference of tumor phylogenies with improved somatic mutation discovery

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5663439

Exome sequencing identifies frequent inactivating mutations in BAP1, ARID1A and PBRM1 in intrahepatic cholangiocarcinomas

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5663439

Cumulative haploinsufficiency and triplosensitivity drive aneuploidy patterns and shape the cancer genome

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5663439

Target inference from collections of genomic intervals

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5663439

23 June 2018

Cancer genome landscapes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5663439

Half or more of the somatic mutations in cancers of self-renewing tissues originate prior to tumor initiation

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5663439

CRAVAT: cancer-related analysis of variants toolkit

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5663439

Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5663439

Clinical significance of the genetic landscape of pancreatic cancer and implications for identification of potential long-term survivors

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5663439

Genetic basis of pancreas cancer development and progression: insights from whole-exome and whole-genome sequencing

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5663439

The molecular evolution of acquired resistance to targeted EGFR blockade in colorectal cancers

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5663439

Emergence of KRAS mutations and acquired resistance to anti-EGFR therapy in colorectal cancer

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5663439

Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5663439

Clonal evolution in cancer

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5663439

Control-FREEC: a tool for assessing copy number and allelic content using next-generation sequencing data

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5663439

Detection and quantification of rare mutations with massively parallel sequencing

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5663439

Tumour evolution inferred by single-cell sequencing

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5663439

Distant metastasis occurs late during the genetic evolution of pancreatic cancer

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5663439

The patterns and dynamics of genomic instability in metastatic pancreatic cancer

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5663439

A census of amplified and overexpressed human cancer genes

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5663439

Circos: an information aesthetic for comparative genomics

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5663439

Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5663439

Metastasis: from dissemination to organ-specific colonization

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5663439

The pathology and genetics of metastatic pancreatic cancer

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5663439

Core signaling pathways in human pancreatic cancers revealed by global genomic analyses

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5663439

Subclonal phylogenetic structures in cancer revealed by ultra-deep sequencing

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5663439

Comparative lesion sequencing provides insights into tumor evolution

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5663439

The epigenomics of cancer

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5663439

Genetic clonal diversity predicts progression to esophageal adenocarcinoma

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5663439

Immortalizing the complexity of cancer metastasis: genetic features of lethal metastatic pancreatic cancer obtained from rapid autopsy

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5663439

Missense mutations of MADH4: characterization of the mutational hot spot and functional consequences in human tumors

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5663439

Somatic mosaicism: on the road to cancer.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5663439

Intratumor heterogeneity in localized lung adenocarcinomas delineated by multiregion sequencing

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5663439

Secondary mutations inBRCA2associated with clinical resistance to a PARP inhibitor

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5663439

Reconstructing metastatic seeding patterns of human cancers

3 December 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNG.3764

inferred from DOI database lookup

7 January 2021

based on heuristic

The European Genome-phenome Archive of human data consented for biomedical research.

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNG.3764

inferred from DOI database lookup

7 January 2021

based on heuristic

Abrogation of the Rb/p16 tumor-suppressive pathway in virtually all pancreatic carcinomas

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28092682

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NG.3764

1 reference

15 June 2018

Dimensions Publication ID

0 references

1 reference

15 June 2018

PubMed publication ID

28092682

1 reference

15 June 2018