(Q38791607)

6 September 2017

Chronic inflammatory airway diseases: the central role of the epithelium revisited (English)

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6 September 2017

S T Gohy

1

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6 September 2017

C Hupin

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2

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6 September 2017

C Pilette

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3

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6 September 2017

M Z Ladjemi

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4

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6 September 2017

1 April 2016

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Clinical & Experimental Allergy

6 September 2017

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6 September 2017

46

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6 September 2017

4

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6 September 2017

529-542

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Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010

6 September 2017

1 reference

The burden of allergic rhinitis and asthma

21 January 2018

1 reference

Bronchial epithelium as a target for innovative treatments in asthma

21 January 2018

1 reference

The airway epithelium: structural and functional properties in health and disease

21 January 2018

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Airway epithelial cells: current concepts and challenges.

21 January 2018

1 reference

Epithelium dysfunction in asthma

21 January 2018

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Hypoxia-inducible factor 1 mediates nasal polypogenesis by inducing epithelial-to-mesenchymal transition

21 January 2018

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Imprinting of the COPD airway epithelium for dedifferentiation and mesenchymal transition.

21 January 2018

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Airway epithelial regulation of pulmonary immune homeostasis and inflammation.

21 January 2018

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Crystal structure of a claudin provides insight into the architecture of tight junctions

21 January 2018

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The tight junction: a multifunctional complex

21 January 2018

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Multifunctional strands in tight junctions

21 January 2018

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Barrier function of airway tract epithelium

21 January 2018

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E-cadherin-mediated adhesion inhibits ligand-dependent activation of diverse receptor tyrosine kinases.

21 January 2018

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Distinct molecular forms of beta-catenin are targeted to adhesive or transcriptional complexes

21 January 2018

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Epithelial injury and repair in airways diseases.

21 January 2018

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Epithelial-mesenchymal transition and its implications for fibrosis

21 January 2018

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Tissue remodelling in chronic bronchial diseases: from the epithelial to mesenchymal phenotype

21 January 2018

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Airway epithelial repair, regeneration, and remodeling after injury in chronic obstructive pulmonary disease

21 January 2018

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Muco-ciliary differentiation of nasal epithelial cells is decreased after wound healing in vitro.

21 January 2018

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Epithelial repair mechanisms in the lung

21 January 2018

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Regulation of human airway surface liquid

21 January 2018

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Normal CFTR inhibits epidermal growth factor receptor-dependent pro-inflammatory chemokine production in human airway epithelial cells

21 January 2018

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Antimicrobial peptides and proteins in the innate defense of the airway surface

21 January 2018

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Downregulation of polymeric immunoglobulin receptor and secretory IgA antibodies in eosinophilic upper airway diseases.

21 January 2018

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Mucins: a biologically relevant glycan barrier in mucosal protection

21 January 2018

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Structure and function of the polymeric mucins in airways mucus.

21 January 2018

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Cationic polypeptides are required for antibacterial activity of human airway fluid.

21 January 2018

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Mammalian defensins in the antimicrobial immune response

21 January 2018

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Mechanisms for induction of acquired host immunity by neutrophil peptide defensins

21 January 2018

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Cathelicidin LL-37 increases lung epithelial cell stiffness, decreases transepithelial permeability, and prevents epithelial invasion by Pseudomonas aeruginosa.

21 January 2018

1 reference

Up-regulation of S100A8 and S100A9 protein in bronchial epithelial cells by lipopolysaccharide.

21 January 2018

1 reference

Secretory leukocyte protease inhibitor and elafin/trappin-2: versatile mucosal antimicrobials and regulators of immunity.

21 January 2018

1 reference

Epithelial cells trigger frontline immunoglobulin class switching through a pathway regulated by the inhibitor SLPI.

21 January 2018

1 reference

Prostaglandin, leukotriene, and lipoxin balance in chronic rhinosinusitis with and without nasal polyposis

21 January 2018

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Roles of cysteinyl leukotrienes in airway inflammation, smooth muscle function, and remodeling

21 January 2018

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Mediators of chronic obstructive pulmonary disease

21 January 2018

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Innate immunity in the lung: how epithelial cells fight against respiratory pathogens

21 January 2018

1 reference

Innate immunity in the respiratory epithelium.

21 January 2018

1 reference

Toll-like receptors and their crosstalk with other innate receptors in infection and immunity

21 January 2018

1 reference

DAMPs activating innate and adaptive immune responses in COPD.

21 January 2018

1 reference

The danger within: endogenous danger signals, atopy and asthma

21 January 2018

1 reference

Innate and adaptive immune responses in asthma

21 January 2018

1 reference

Bronchial epithelial cells: The key effector cells in the pathogenesis of chronic obstructive pulmonary disease?

21 January 2018

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Group 2 innate lymphoid cells facilitate sensitization to local, but not systemic, TH2-inducing allergen exposures

21 January 2018

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Preferential recruitment of CCR6-expressing Th17 cells to inflamed joints via CCL20 in rheumatoid arthritis and its animal model.

21 January 2018

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The nucleotide-binding domain, leucine-rich repeat protein 3 inflammasome/IL-1 receptor I axis mediates innate, but not adaptive, immune responses after exposure to particulate matter under 10 μm.

21 January 2018

1 reference

Many chemokines including CCL20/MIP-3alpha display antimicrobial activity.

21 January 2018

1 reference

CCL17/thymus and activation-regulated chemokine induces calcitonin gene-related peptide in human airway epithelial cells through CCR4.

21 January 2018

1 reference

Critical role of constitutive type I interferon response in bronchial epithelial cell to influenza infection

21 January 2018

1 reference

B Cell-Activating Factor. An Orchestrator of Lymphoid Follicles in Severe Chronic Obstructive Pulmonary Disease

21 January 2018

1 reference

Lymphoid follicle cells in chronic obstructive pulmonary disease overexpress the chemokine receptor CXCR3.

21 January 2018

1 reference

The immune geography of IgA induction and function

21 January 2018

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Immunoglobulin transport across polarized epithelial cells

21 January 2018

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Beyond immediate hypersensitivity: evolving roles for IgE antibodies in immune homeostasis and allergic diseases

21 January 2018

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Asthmatic bronchial epithelial cells have a deficient innate immune response to infection with rhinovirus

21 January 2018

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Mild and moderate asthma is associated with airway goblet cell hyperplasia and abnormalities in mucin gene expression

21 January 2018

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Smoking is associated with shortened airway cilia

21 January 2018

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Ciliary beating is depressed in nasal cilia from chronic obstructive pulmonary disease subjects

21 January 2018

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Cigarette smoke total particulate matter increases mucous secreting cell numbers in vitro: a potential model of goblet cell hyperplasia

21 January 2018

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Involvement of the epidermal growth factor receptor in epithelial repair in asthma

21 January 2018

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Matrix metalloproteinase-14 mediates a phenotypic shift in the airways to increase mucin production.

21 January 2018

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Metalloproteinases mediate mucin 5AC expression by epidermal growth factor receptor activation.

21 January 2018

1 reference

IL-13-induced changes in the goblet cell density of human bronchial epithelial cell cultures: MAP kinase and phosphatidylinositol 3-kinase regulation

21 January 2018

1 reference

Influenza A induces the major secreted airway mucin MUC5AC in a protease-EGFR-extracellular regulated kinase-Sp1-dependent pathway.

21 January 2018

1 reference

S100A8, S100A9 and S100A12 activate airway epithelial cells to produce MUC5AC via extracellular signal-regulated kinase and nuclear factor-κB pathways

21 January 2018

1 reference

Stimulation of airway mucin gene expression by interleukin (IL)-17 through IL-6 paracrine/autocrine loop

21 January 2018

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Dual oxidase 1-dependent MUC5AC mucin expression in cultured human airway epithelial cells

21 January 2018

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Intrinsic phenotypic differences of asthmatic epithelium and its inflammatory responses to respiratory syncytial virus and air pollution

21 January 2018

1 reference

Airway Basal stem/progenitor cells have diminished capacity to regenerate airway epithelium in chronic obstructive pulmonary disease.

21 January 2018

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Remodeling and inflammation of bronchi in asthma and chronic obstructive pulmonary disease

21 January 2018

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Delay of airway epithelial wound repair in COPD is associated with airflow obstruction severity

21 January 2018

1 reference

Cigarette smoking reprograms apical junctional complex molecular architecture in the human airway epithelium in vivo

21 January 2018

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Epithelial to mesenchymal transition is increased in patients with COPD and induced by cigarette smoke

21 January 2018

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Abnormalities in airway epithelial junction formation in chronic obstructive pulmonary disease.

21 January 2018

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Rhinovirus disrupts the barrier function of polarized airway epithelial cells

21 January 2018

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Disruption of tight junctions during traversal of the respiratory epithelium by Burkholderia cenocepacia

21 January 2018

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Der p 1 facilitates transepithelial allergen delivery by disruption of tight junctions

21 January 2018

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Pollen proteolytic enzymes degrade tight junctions

21 January 2018

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Pseudomonas aeruginosa exploits a PIP3-dependent pathway to transform apical into basolateral membrane

21 January 2018

1 reference

Inflammatory features of nasal mucosa in smokers with and without COPD.

21 January 2018

1 reference

Comparison of the structural and inflammatory features of COPD and asthma. Giles F. Filley Lecture.

21 January 2018

1 reference

Chronic obstructive pulmonary disease: molecular and cellularmechanisms

21 January 2018

1 reference

Squamous metaplasia amplifies pathologic epithelial-mesenchymal interactions in COPD patients

21 January 2018

1 reference

Chronic respiratory aeroallergen exposure in mice induces epithelial-mesenchymal transition in the large airways

21 January 2018

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Induction of epithelial-mesenchymal transition in primary airway epithelial cells from patients with asthma by transforming growth factor-beta1.

21 January 2018

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Reticular basement membrane fragmentation and potential epithelial mesenchymal transition is exaggerated in the airways of smokers with chronic obstructive pulmonary disease.

21 January 2018

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Evaluation of epithelial mesenchymal transition in patients with chronic obstructive pulmonary disease

21 January 2018

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Epithelial-mesenchymal transition in the pathophysiology of airway remodelling in asthma

21 January 2018

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Transforming growth factor-beta1 in inflammatory airway disease: a key for understanding inflammation and remodeling

21 January 2018

1 reference

Epithelial-mesenchymal transition in lung development and disease: does it exist and is it important?

21 January 2018

1 reference

TGF-beta-induced epithelial to mesenchymal transition

21 January 2018

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Smad-dependent and Smad-independent pathways in TGF-beta family signalling

21 January 2018

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Nicotine-induced epithelial-mesenchymal transition via Wnt/β-catenin signaling in human airway epithelial cells

21 January 2018

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Hedgehog/Gli promotes epithelial-mesenchymal transition in lung squamous cell carcinomas.

21 January 2018

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Free radical generation induces epithelial-to-mesenchymal transition in lung epithelium via a TGF-β1-dependent mechanism

21 January 2018

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Role of aberrant WNT signalling in the airway epithelial response to cigarette smoke in chronic obstructive pulmonary disease

21 January 2018

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House dust mite-promoted epithelial-to-mesenchymal transition in human bronchial epithelium.

21 January 2018

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Epithelial-mesenchymal transition in primary human bronchial epithelial cells is Smad-dependent and enhanced by fibronectin and TNF-alpha

21 January 2018

1 reference

IL-22 contributes to TGF-β1-mediated epithelial-mesenchymal transition in asthmatic bronchial epithelial cells

21 January 2018

1 reference

Apoptosis and loss of adhesion of bronchial epithelial cells in asthma

21 January 2018

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Molecular mechanisms of epithelial-mesenchymal transition

21 January 2018

1 reference

Disruption of E-cadherin-mediated adhesion induces a functionally distinct pathway of dendritic cell maturation

21 January 2018

1 reference

Down-regulation of E-cadherin in human bronchial epithelial cells leads to epidermal growth factor receptor-dependent Th2 cell-promoting activity.

21 January 2018

1 reference

Respiratory tract mucin genes and mucin glycoproteins in health and disease

21 January 2018

1 reference

Goblet cell and mucin gene abnormalities in asthma

21 January 2018

1 reference

Airway mucus function and dysfunction

21 January 2018

1 reference

21 January 2018

Mucus and MUC in asthma

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Characterization of human mucin 5B gene expression in airway epithelium and the genomic clone of the amino-terminal and 5'-flanking region

21 January 2018

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Mucin expression in peripheral airways of patients with chronic obstructive pulmonary disease.

21 January 2018

1 reference

Downregulation of secretory leukocyte proteinase inhibitor in chronic obstructive lung disease: the role of TGF-beta/Smads signaling pathways

21 January 2018

1 reference

Severe asthma is associated with a loss of LX4, an endogenous anti-inflammatory compound

21 January 2018

1 reference

Diminished lipoxin biosynthesis in severe asthma

21 January 2018

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Airway lipoxin A4 generation and lipoxin A4 receptor expression are decreased in severe asthma

21 January 2018

1 reference

Interleukin 25 promotes the initiation of proallergic type 2 responses.

21 January 2018

1 reference

Thymic stromal lymphopoietin as a key initiator of allergic airway inflammation in mice

21 January 2018

1 reference

Regulation and function of the IL-1 family cytokine IL-1F9 in human bronchial epithelial cells

21 January 2018

1 reference

Interleukin-8 gene expression by a pulmonary epithelial cell line. A model for cytokine networks in the lung

21 January 2018

1 reference

Alveolar type II epithelial cells produce interleukin-6 in vitro and in vivo. Regulation by alveolar macrophage secretory products

21 January 2018

1 reference

Polymeric immunoglobulin receptor down-regulation in chronic obstructive pulmonary disease. Persistence in the cultured epithelium and role of transforming growth factor-β.

21 January 2018

1 reference

Activation of bronchial epithelial cells in smokers without airway obstruction and patients with COPD.

21 January 2018

1 reference

Increased IgA production by B-cells in COPD via lung epithelial interleukin-6 and TACI pathways

21 January 2018

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Intrinsic biochemical and functional differences in bronchial epithelial cells of children with asthma.

21 January 2018

1 reference

Mucosal immunity in asthma and chronic obstructive pulmonary disease: a role for immunoglobulin A?

21 January 2018

1 reference

Local release of B cell-activating factor of the TNF family after segmental allergen challenge of allergic subjects

21 January 2018

1 reference

Bronchial secretory immunoglobulin a deficiency correlates with airway inflammation and progression of chronic obstructive pulmonary disease

21 January 2018

1 reference

The regulation of immunoglobulin E class-switch recombination

21 January 2018

1 reference

IgE in allergy and asthma today

21 January 2018

1 reference

CD23-dependent transcytosis of IgE and immune complex across the polarized human respiratory epithelial cells

21 January 2018

1 reference

Effects of ciclesonide and fluticasone propionate on allergen-induced airway inflammation and remodeling features.

21 January 2018

1 reference

A randomized controlled trial of inhaled corticosteroids (ICS) on markers of epithelial-mesenchymal transition (EMT) in large airway samples in COPD: an exploratory proof of concept study

21 January 2018

1 reference

TGF-beta1 induced epithelial to mesenchymal transition (EMT) in human bronchial epithelial cells is enhanced by IL-1beta but not abrogated by corticosteroids.

21 January 2018

1 reference

GRbeta expression in nasal polyp inflammatory cells and its relationship to the anti-inflammatory effects of intranasal fluticasone

21 January 2018

1 reference

Corticosteroid resistance in patients with asthma and chronic obstructive pulmonary disease.

21 January 2018

1 reference

Mechanisms of impaired beta-adrenoceptor-induced airway relaxation by interleukin-1beta in vivo in the rat.

21 January 2018

1 reference

Cytokine release and adhesion molecule expression by stimulated human bronchial epithelial cells are downregulated by salmeterol.

21 January 2018

1 reference

β₂ long-acting and anticholinergic drugs control TGF-β1-mediated neutrophilic inflammation in COPD.

21 January 2018

1 reference

Transforming growth factor-β1 and cigarette smoke inhibit the ability of β2-agonists to enhance epithelial permeability

21 January 2018

1 reference

mAChRs activation induces epithelial-mesenchymal transition on lung epithelial cells

21 January 2018

1 reference

Regional differences in susceptibiity of bronchial epithelium to mesenchymal transition and inhibition by the macrolide antibiotic azithromycin.

21 January 2018

1 reference

Macrolides attenuate phorbol ester-induced tumor necrosis factor-α and mucin production from human airway epithelial cells

21 January 2018

1 reference

Azithromycin maintenance treatment in patients with frequent exacerbations of chronic obstructive pulmonary disease (COLUMBUS): a randomised, double-blind, placebo-controlled trial.

21 January 2018

1 reference

A soluble thymic stromal lymphopoietin (TSLP) antagonist, TSLPR-immunoglobulin, reduces the severity of allergic disease by regulating pulmonary dendritic cells

21 January 2018

1 reference

The safety and efficacy of infliximab in moderate to severe chronic obstructive pulmonary disease

21 January 2018

1 reference

Efficacy and safety of a monoclonal antibody recognizing interleukin-8 in COPD: a pilot study.

21 January 2018

1 reference

Tgf-Beta isoform specific regulation of airway inflammation and remodelling in a murine model of asthma

21 January 2018

1 reference

Chronic obstructive pulmonary disease phenotypes: the future of COPD.

21 January 2018

1 reference

Evidence for Temporary Slowing of Mucociliary Clearance in the Lung caused by Tobacco Smoking

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1111/CEA.12712

1 reference

6 September 2017

1 reference