(Q38831994)

English

Statins activate the canonical hedgehog-signaling and aggravate non-cirrhotic portal hypertension, but inhibit the non-canonical hedgehog signaling and cirrhotic portal hypertension.

scientific article published on 28 September 2015

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26412302%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

Statins activate the canonical hedgehog-signaling and aggravate non-cirrhotic portal hypertension, but inhibit the non-canonical hedgehog signaling and cirrhotic portal hypertension (English)

1 reference

Europe PubMed Central

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25 February 2020

arterial hypertension

0 references

portal hypertension

1 reference

based on heuristic

inferred from title

non-cirrhotic portal hypertension

1 reference

based on heuristic

inferred from title

Frank E Uschner

1

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26412302%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

Robert Schierwagen

6

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25 February 2020

14

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25 February 2020

Sabine D. Klein

5

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Sabine Klein

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25 February 2020

Christian Strassburg

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Christian P Strassburg

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25 February 2020

Peter F M van der Ven

9

object named as

Peter F M van der Ven

1 reference

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25 February 2020

Michaela Granzow

4

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Michaela Granzow

1 reference

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25 February 2020

Sebastian Gautsch

8

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Sebastian Gautsch

1 reference

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25 February 2020

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Ganesh Ranabhat

2

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25 February 2020

Steve S Choi

3

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25 February 2020

Esther Raskopf

7

1 reference

Europe PubMed Central

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25 February 2020

Dieter O Fürst

10

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Europe PubMed Central

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25 February 2020

Tilman Sauerbruch

12

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Europe PubMed Central

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25 February 2020

Anna Mae Diehl

13

1 reference

Europe PubMed Central

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25 February 2020

language of work or name

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publication date

28 September 2015

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Europe PubMed Central

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25 February 2020

Scientific Reports

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26412302%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

5

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26412302%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

14573

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26412302%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

copyright license

Creative Commons Attribution 4.0 International

28 September 2015

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

https://scigraph.springernature.com/pub.10.1038/srep14573

0 references

Statin use is associated with a reduced risk of fibrosis progression in chronic hepatitis C

1 reference

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9 September 2017

Hedgehog inhibition reduces angiogenesis by downregulation of tumoral VEGF-A expression in hepatocellular carcinoma

1 reference

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9 September 2017

Toxic damage increases angiogenesis and metastasis in fibrotic livers via PECAM-1.

1 reference

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9 September 2017

Hedgehog signalling regulates liver sinusoidal endothelial cell capillarisation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4585958

9 September 2017

Hedgehog signaling in cholangiocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4585958

9 September 2017

Retracted: Up-Regulation of Sonic Hedgehog Contributes to TGF-β1-Induced Epithelial to Mesenchymal Transition in NSCLC Cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4585958

9 September 2017

Hedgehog signaling in the liver

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4585958

9 September 2017

Interactions between Hedgehog proteins and their binding partners come into view

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4585958

9 September 2017

Leptin promotes the myofibroblastic phenotype in hepatic stellate cells by activating the hedgehog pathway.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4585958

9 September 2017

Signals from dying hepatocytes trigger growth of liver progenitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4585958

9 September 2017

Hedgehog proteins activate pro-angiogenic responses in endothelial cells through non-canonical signaling pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4585958

9 September 2017

Hedgehog pathway activation and epithelial-to-mesenchymal transitions during myofibroblastic transformation of rat hepatic cells in culture and cirrhosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4585958

9 September 2017

Mechanisms of hepatic fibrogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4585958

9 September 2017

Atorvastatin lowers portal pressure in cirrhotic rats by inhibition of RhoA/Rho-kinase and activation of endothelial nitric oxide synthase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4585958

9 September 2017

In vitro scratch assay: a convenient and inexpensive method for analysis of cell migration in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4585958

9 September 2017

Rho GTPases, statins, and nitric oxide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4585958

9 September 2017

Portal hypertension: from bedside to bench.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4585958

9 September 2017

Characterisation of portal hypertension models by microspheres in anaesthetised rats: a comparison of liver flow

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4585958

9 September 2017

Complications of cirrhosis. I. Portal hypertension.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4585958

9 September 2017

Bacterial translocation in cirrhotic rats stimulates eNOS-derived NO production and impairs mesenteric vascular contractility

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4585958

9 September 2017

Plasminogen fragment K1-5 improves survival in a murine hepatocellular carcinoma model.

1 reference

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14 September 2017

Angiotensin-II type 1 receptor-mediated Janus kinase 2 activation induces liver fibrosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4585958

25 September 2017

Multiple roles of cholesterol in hedgehog protein biogenesis and signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4585958

25 September 2017

Development and evaluation of an open source Delphi-based software for morphometric quantification of liver fibrosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4585958

17 June 2018

Sonic hedgehog induces angiogenesis via Rho kinase-dependent signaling in endothelial cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4585958

17 June 2018

Sonic hedgehog is an autocrine viability factor for myofibroblastic hepatic stellate cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4585958

17 June 2018

KLF2 exerts antifibrotic and vasoprotective effects in cirrhotic rat livers: behind the molecular mechanisms of statins.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4585958

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Expression of vasoactive proteins in gastric antral mucosa reflects vascular dysfunction in patients with cirrhosis and portal hypertension.

1 reference

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Activation of the MAS receptor by angiotensin-(1-7) in the renin-angiotensin system mediates mesenteric vasodilatation in cirrhosis.

1 reference

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1 reference

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1 reference

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Simvastatin lowers portal pressure in patients with cirrhosis and portal hypertension: a randomized controlled trial

1 reference

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1 reference

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1 reference

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Teratogen-mediated inhibition of target tissue response to Shh signaling

1 reference

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Etiology, Management, and Outcome of the Budd-Chiari Syndrome

1 reference

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Acute portal vein thrombosis unrelated to cirrhosis: A prospective multicenter follow-up study

1 reference

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Good long-term outcome of Budd-Chiari syndrome with a step-wise management

1 reference

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Simvastatin treatment improves liver sinusoidal endothelial dysfunction in CCl4 cirrhotic rats

1 reference

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21 January 2018

3-Hydroxy-3-methylglutaryl-CoA reductase inhibitors attenuate vascular smooth muscle proliferation by preventing rho GTPase-induced down-regulation of p27(Kip1)

1 reference

https://pubmed.ncbi.nlm.nih.gov/26412302

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Atorvastatin inhibits proliferation and apoptosis, but induces senescence in hepatic myofibroblasts and thereby attenuates hepatic fibrosis in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/26412302

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hedgehog-mediated mesenchymal–epithelial interactions modulate hepatic response to bile duct ligation

1 reference

https://pubmed.ncbi.nlm.nih.gov/26412302

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Post-transcriptional regulation of endothelial nitric oxide synthase mRNA stability by Rho GTPase

1 reference

https://pubmed.ncbi.nlm.nih.gov/26412302

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The morphogen Sonic hedgehog is an indirect angiogenic agent upregulating two families of angiogenic growth factors

1 reference

https://pubmed.ncbi.nlm.nih.gov/26412302

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/SREP14573

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26412302%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

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release_32r3ysc57jcydihwp7i6vr2huy

1 reference

https://api.fatcat.wiki/v0/release/32r3ysc57jcydihwp7i6vr2huy

24 November 2022

based on heuristic

mapped directly with Wikidata item

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26412302%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26412302%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

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