(Q38847942)

English

C-Terminally Truncated Forms of Tau, But Not Full-Length Tau or Its C-Terminal Fragments, Are Released from Neurons Independently of Cell Death.

scientific article published on July 2015

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scholarly article

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Europe PubMed Central

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20 February 2020

C-Terminally Truncated Forms of Tau, But Not Full-Length Tau or Its C-Terminal Fragments, Are Released from Neurons Independently of Cell Death (English)

1 reference

Europe PubMed Central

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20 February 2020

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Tiernan T O'Malley

5

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20 February 2020

6

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20 February 2020

Tracy L Young-Pearse

7

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20 February 2020

Dennis J. Selkoe

8

object named as

Dennis J Selkoe

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20 February 2020

author name string

Daniel Kanmert

1

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20 February 2020

Adam Cantlon

2

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20 February 2020

Christina R Muratore

3

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20 February 2020

Ming Jin

4

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20 February 2020

Dominic M Walsh

9

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20 February 2020

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publication date

1 July 2015

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20 February 2020

Journal of Neuroscience

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20 February 2020

35

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20 February 2020

10851-10865

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20 February 2020

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20 February 2020

describes a project that uses

1 reference

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC6605107/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Soluble oligomers of beta amyloid (1-42) inhibit long-term potentiation but not long-term depression in rat dentate gyrus.

1 reference

https://pubmed.ncbi.nlm.nih.gov/26224867

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cerebrospinal fluid markers for Alzheimer's disease evaluated after acute ischemic stroke.

1 reference

https://pubmed.ncbi.nlm.nih.gov/26224867

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tau paired helical filaments from Alzheimer's disease brain and assembled in vitro are based on beta-structure in the core domain

1 reference

https://pubmed.ncbi.nlm.nih.gov/26224867

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The formation of straight and twisted filaments from short tau peptides

1 reference

https://pubmed.ncbi.nlm.nih.gov/26224867

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Purification of recombinant tau protein and preparation of Alzheimer-paired helical filaments in vitro.

1 reference

https://pubmed.ncbi.nlm.nih.gov/26224867

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Solution state characterization of amyloid beta-derived diffusible ligands

1 reference

https://pubmed.ncbi.nlm.nih.gov/26224867

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Culturing hippocampal neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/26224867

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolation and characterization of exosomes from cell culture supernatants and biological fluids

1 reference

https://pubmed.ncbi.nlm.nih.gov/26224867

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of tau in cerebrospinal fluid using mass spectrometry.

1 reference

https://pubmed.ncbi.nlm.nih.gov/26224867

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Assessment of cell viability in primary neuronal cultures

1 reference

https://pubmed.ncbi.nlm.nih.gov/26224867

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A facile method for expression and purification of the Alzheimer's disease-associated amyloid beta-peptide

1 reference

https://pubmed.ncbi.nlm.nih.gov/26224867

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Propagation of tau misfolding from the outside to the inside of a cell.

1 reference

https://pubmed.ncbi.nlm.nih.gov/26224867

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

gamma-secretase processing of APLP1 leads to the production of a p3-like peptide that does not aggregate and is not toxic to neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/26224867

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transmission and spreading of tauopathy in transgenic mouse brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/26224867

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypothetical model of dynamic biomarkers of the Alzheimer's pathological cascade

1 reference

https://pubmed.ncbi.nlm.nih.gov/26224867

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interneuronal transfer of human tau between Lamprey central neurons in situ

1 reference

https://pubmed.ncbi.nlm.nih.gov/26224867

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Secretion of human tau fragments resembling CSF-tau in Alzheimer's disease is modulated by the presence of the exon 2 insert.

1 reference

https://pubmed.ncbi.nlm.nih.gov/26224867

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Specification of region-specific neurons including forebrain glutamatergic neurons from human induced pluripotent stem cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/26224867

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Seeding of normal Tau by pathological Tau conformers drives pathogenesis of Alzheimer-like tangles

1 reference

https://pubmed.ncbi.nlm.nih.gov/26224867

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tau transgenic mice as models for cerebrospinal fluid tau biomarkers.

1 reference

https://pubmed.ncbi.nlm.nih.gov/26224867

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interaction between prion protein and toxic amyloid β assemblies can be therapeutically targeted at multiple sites

1 reference

https://pubmed.ncbi.nlm.nih.gov/26224867

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunotherapy for tauopathies.

1 reference

https://pubmed.ncbi.nlm.nih.gov/26224867

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Exosome-associated tau is secreted in tauopathy models and is selectively phosphorylated in cerebrospinal fluid in early Alzheimer disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/26224867

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proteostasis of tau. Tau overexpression results in its secretion via membrane vesicles.

1 reference

https://pubmed.ncbi.nlm.nih.gov/26224867

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Propagation of tau pathology in a model of early Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/26224867

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Trans-cellular propagation of Tau aggregation by fibrillar species

1 reference

https://pubmed.ncbi.nlm.nih.gov/26224867

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tau and tauopathies

1 reference

https://pubmed.ncbi.nlm.nih.gov/26224867

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hyperphosphorylation and cleavage at D421 enhance tau secretion

1 reference

https://pubmed.ncbi.nlm.nih.gov/26224867

12 December 2020

based on heuristic

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Constitutive secretion of tau protein by an unconventional mechanism.

1 reference

https://pubmed.ncbi.nlm.nih.gov/26224867

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biochemistry and cell biology of tau protein in neurofibrillary degeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/26224867

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The ELISA-measured increase in cerebrospinal fluid tau that discriminates Alzheimer's disease from other neurodegenerative disorders is not attributable to differential recognition of tau assembly forms

1 reference

https://pubmed.ncbi.nlm.nih.gov/26224867

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Extracellular Tau levels are influenced by variability in Tau that is associated with tauopathies

1 reference

https://pubmed.ncbi.nlm.nih.gov/26224867

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alzheimer brain-derived amyloid β-protein impairs synaptic remodeling and memory consolidation

1 reference

https://pubmed.ncbi.nlm.nih.gov/26224867

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Physiological release of endogenous tau is stimulated by neuronal activity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/26224867

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tau pathology and neurodegeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/26224867

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dynamics of hippocampal neurogenesis in adult humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/26224867

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Spreading of tau pathology in Alzheimer's disease by cell-to-cell transmission

1 reference

https://pubmed.ncbi.nlm.nih.gov/26224867

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Changes in amyloid-β and Tau in the cerebrospinal fluid of transgenic mice overexpressing amyloid precursor protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/26224867

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of novel CSF Tau and ptau biomarkers for Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/26224867

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The familial Alzheimer's disease APPV717I mutation alters APP processing and Tau expression in iPSC-derived neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/26224867

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Passive immunization with Tau oligomer monoclonal antibody reverses tauopathy phenotypes without affecting hyperphosphorylated neurofibrillary tangles.

1 reference

https://pubmed.ncbi.nlm.nih.gov/26224867

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aβ dimers differ from monomers in structural propensity, aggregation paths and population of synaptotoxic assemblies.

1 reference

https://pubmed.ncbi.nlm.nih.gov/26224867

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Specificity of anti-tau antibodies when analyzing mice models of Alzheimer's disease: problems and solutions

1 reference

https://pubmed.ncbi.nlm.nih.gov/26224867

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stages and conformations of the Tau repeat domain during aggregation and its effect on neuronal toxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/26224867

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The intersection of amyloid beta and tau at synapses in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/26224867

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prion-like properties of Tau protein: the importance of extracellular Tau as a therapeutic target

1 reference

https://pubmed.ncbi.nlm.nih.gov/26224867

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Divergent CSF τ alterations in two common tauopathies: Alzheimer's disease and progressive supranuclear palsy

1 reference

https://pubmed.ncbi.nlm.nih.gov/26224867

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison and optimization of hiPSC forebrain cortical differentiation protocols

1 reference

https://pubmed.ncbi.nlm.nih.gov/26224867

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proteopathic tau seeding predicts tauopathy in vivo.

1 reference

https://pubmed.ncbi.nlm.nih.gov/26224867

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human secreted tau increases amyloid-beta production

1 reference

https://pubmed.ncbi.nlm.nih.gov/26224867

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tau immunization: a cautionary tale?

1 reference

https://pubmed.ncbi.nlm.nih.gov/26224867

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tau protein in cerebrospinal fluid: a biochemical marker for axonal degeneration in Alzheimer disease?

1 reference

https://pubmed.ncbi.nlm.nih.gov/26224867

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of heterogeneous A4 peptides in human cerebrospinal fluid and blood by a newly developed sensitive Western blot assay.

1 reference

https://pubmed.ncbi.nlm.nih.gov/26224867

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The tau protein in human cerebrospinal fluid in Alzheimer's disease consists of proteolytically derived fragments

1 reference

https://pubmed.ncbi.nlm.nih.gov/26224867

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins

1 reference

https://pubmed.ncbi.nlm.nih.gov/26224867

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.0387-15.2015

1 reference

Europe PubMed Central

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20 February 2020

1 reference

Europe PubMed Central

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20 February 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26224867%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

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