(Q53352144)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24785004%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

title

Aβ dimers differ from monomers in structural propensity, aggregation paths and population of synaptotoxic assemblies (English)

1 reference

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17 March 2020

6

1 reference

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17 March 2020

Tiernan T O'Malley

1

1 reference

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17 March 2020

Nur Alia Oktaviani

2

1 reference

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17 March 2020

Michael J Rowan

8

1 reference

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17 March 2020

Frans A.A. Mulder

9

1 reference

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17 March 2020

7

George B Benedek

1 reference

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17 March 2020

author name string

Dainan Zhang

3

1 reference

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17 March 2020

Aleksey Lomakin

4

1 reference

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17 March 2020

Brian O'Nuallain

5

1 reference

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17 March 2020

Dominic M Walsh

10

1 reference

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17 March 2020

language of work or name

English

0 references

publication date

1 August 2014

1 reference

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17 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24785004%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

volume

461

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17 March 2020

issue

3

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17 March 2020

page(s)

413-426

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Alzheimer disease in the United States (2010-2050) estimated using the 2010 census

17 March 2020

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Targeting small Abeta oligomers: the solution to an Alzheimer's disease conundrum?

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Amyloid beta protein dimer-containing human CSF disrupts synaptic plasticity: prevention by systemic passive immunization

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Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins

21 January 2018

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Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory

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Water-soluble Abeta (N-40, N-42) oligomers in normal and Alzheimer disease brains.

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Soluble amyloid beta peptide concentration as a predictor of synaptic change in Alzheimer's disease

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The presence of sodium dodecyl sulphate-stable Abeta dimers is strongly associated with Alzheimer-type dementia.

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Soluble pool of Abeta amyloid as a determinant of severity of neurodegeneration in Alzheimer's disease

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Interaction between prion protein and toxic amyloid β assemblies can be therapeutically targeted at multiple sites

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Soluble amyloid beta-protein dimers isolated from Alzheimer cortex directly induce Tau hyperphosphorylation and neuritic degeneration

21 January 2018

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Amyloid beta-protein dimers rapidly form stable synaptotoxic protofibrils

21 January 2018

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A disulfide-linked amyloid-beta peptide dimer forms a protofibril-like oligomer through a distinct pathway from amyloid fibril formation

21 January 2018

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Molecular pathology of dityrosine cross-links in proteins: structural and functional analysis of four proteins

21 January 2018

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A central role for dityrosine crosslinking of Amyloid-β in Alzheimer's disease.

21 January 2018

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Dimerisation of N-acetyl-L-tyrosine ethyl ester and Abeta peptides via formation of dityrosine

21 January 2018

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In vitro peroxidase oxidation induces stable dimers of beta-amyloid (1-42) through dityrosine bridge formation

21 January 2018

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Dityrosine Cross-Linked Aβ Peptides: Fibrillar β-Structure in Aβ(1-40) Is Conducive to Formation of Dityrosine Cross-Links but a Dityrosine Cross-Link in Aβ(8-14) Does Not Induce β-Structure

21 January 2018

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The recombinant amyloid-beta peptide Abeta1-42 aggregates faster and is more neurotoxic than synthetic Abeta1-42.

21 January 2018

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A facile method for expression and purification of the Alzheimer's disease-associated amyloid beta-peptide

21 January 2018

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Autoantibodies to redox-modified oligomeric Abeta are attenuated in the plasma of Alzheimer's disease patients.

21 January 2018

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Aggregation and catabolism of disease-associated intra-Abeta mutations: reduced proteolysis of AbetaA21G by neprilysin

21 January 2018

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Soluble amyloid-beta peptides potently disrupt hippocampal synaptic plasticity in the absence of cerebrovascular dysfunction in vivo.

21 January 2018

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Amyloid beta-protein fibrillogenesis. Detection of a protofibrillar intermediate.

21 January 2018

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Protein production by auto-induction in high density shaking cultures

21 January 2018

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NMRPipe: a multidimensional spectral processing system based on UNIX pipes

21 January 2018

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ncIDP-assign: a SPARKY extension for the effective NMR assignment of intrinsically disordered proteins.

21 January 2018

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Recommendations for the presentation of NMR structures of proteins and nucleic acids. IUPAC-IUBMB-IUPAB Inter-Union Task Group on the Standardization of Data Bases of Protein and Nucleic Acid Structures Determined by NMR Spectroscopy

21 January 2018

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Sequence-specific random coil chemical shifts of intrinsically disordered proteins

21 January 2018

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Using NMR chemical shifts to calculate the propensity for structural order and disorder in proteins.

21 January 2018

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Clinical and biomarker changes in dominantly inherited Alzheimer's disease

21 January 2018

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Cerebrospinal fluid levels of β-amyloid 1-42, but not of tau, are fully changed already 5 to 10 years before the onset of Alzheimer dementia

21 January 2018

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Deciphering the molecular basis of memory failure in Alzheimer's disease

21 January 2018

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Amyloid-beta-induced neuronal dysfunction in Alzheimer's disease: from synapses toward neural networks

21 January 2018

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21 January 2018

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Stabilization of a -hairpin in monomeric Alzheimer's amyloid- peptide inhibits amyloid formation

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Structural characterization of a soluble amyloid beta-peptide oligomer.

21 January 2018

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Stabilization of neurotoxic Alzheimer amyloid-beta oligomers by protein engineering

21 January 2018

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Molecular plasticity regulates oligomerization and cytotoxicity of the multipeptide-length amyloid-β peptide pool

21 January 2018

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Neurotoxicity of Alzheimer's disease Aβ peptides is induced by small changes in the Aβ42 to Aβ40 ratio

21 January 2018

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Structural basis for increased toxicity of pathological aβ42:aβ40 ratios in Alzheimer disease

21 January 2018

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Proteases and proteolysis in Alzheimer disease: a multifactorial view on the disease process

21 January 2018

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The role of metallobiology and amyloid-β peptides in Alzheimer's disease

21 January 2018

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Solid-phase synthesis of homodimeric peptides: preparation of covalently-linked dimers of amyloid β peptide

21 January 2018

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Synthetic dityrosine-linked β-amyloid dimers form stable, soluble, neurotoxic oligomers

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1042/BJ20140219

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24785004%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

1 reference