(Q38848268)

7 September 2017

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title

Caloric restriction: beneficial effects on brain aging and Alzheimer's disease (English)

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7 September 2017

0 references

1 reference

Roosmarijn Vandenbroucke

4

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PubMed ID

27240590

7 September 2017

Charysse Vandendriessche

object named as

Charysse Vandendriessche

2

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author name string

Caroline Van Cauwenberghe

1

1 reference

PubMed ID

27240590

7 September 2017

Claude Libert

3

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7 September 2017

30 May 2016

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7 September 2017

20

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inferred from page(s)

published in

Mammalian Genome

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7 September 2017

27

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7 September 2017

7-8

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7 September 2017

300-319

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https://scigraph.springernature.com/pub.10.1007/s00335-016-9647-6

7 September 2017

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cites work

Caloric restriction and age affect synaptic proteins in hippocampal CA3 and spatial learning ability

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

mTOR signaling in cellular and organismal energetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

The key role of growth hormone-insulin-IGF-1 signaling in aging and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Rapamycin increases lifespan and inhibits spontaneous tumorigenesis in inbred female mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Dietary restriction does not prevent nigrostriatal degeneration in the 6-hydroxydopamine model of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

A low dose of dietary resveratrol partially mimics caloric restriction and retards aging parameters in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Effects of environmental enrichment and voluntary exercise on neurogenesis, learning and memory, and pattern separation: BDNF as a critical variable?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Resveratrol increases antioxidant defenses and decreases proinflammatory cytokines in hippocampal astrocyte cultures from newborn, adult and aged Wistar rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Autophagy induction and autophagosome clearance in neurons: relationship to autophagic pathology in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

SIRT1 transgenic mice show phenotypes resembling calorie restriction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

The SIR2 gene family, conserved from bacteria to humans, functions in silencing, cell cycle progression, and chromosome stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Partial rescue of memory deficits induced by calorie restriction in a mouse model of tau deposition

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Molecular interplay between mammalian target of rapamycin (mTOR), amyloid-beta, and Tau: effects on cognitive impairments

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

mTOR regulates tau phosphorylation and degradation: implications for Alzheimer's disease and other tauopathies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

A network pharmacology approach reveals new candidate caloric restriction mimetics in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Calorie restriction: is AMPK a key sensor and effector?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Will calorie restriction work in humans?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Antidiabetic drug metformin (GlucophageR) increases biogenesis of Alzheimer's amyloid peptides via up-regulating BACE1 transcription.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Neuroprotective properties of curcumin in Alzheimer's disease--merits and limitations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Attenuation of sarcopenia by dietary restriction in rhesus monkeys

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Caloric restriction delays disease onset and mortality in rhesus monkeys

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Caloric restriction reduces age-related and all-cause mortality in rhesus monkeys

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Autophagy and aging: keeping that old broom working

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Red wine and equivalent oral pharmacological doses of resveratrol delay vascular aging but do not extend life span in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Histone deacetylases (HDACs): characterization of the classical HDAC family

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Identification of potential caloric restriction mimetics by microarray profiling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Dietary restriction stimulates BDNF production in the brain and thereby protects neurons against excitotoxic injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Dietary restriction normalizes glucose metabolism and BDNF levels, slows disease progression, and increases survival in huntingtin mutant mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Resveratrol inhibits β-amyloid-induced neuronal apoptosis through regulation of SIRT1-ROCK1 signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

The metabolic regulation of aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Late-life rapamycin treatment reverses age-related heart dysfunction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Mice fed rapamycin have an increase in lifespan associated with major changes in the liver transcriptome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Extending healthy life span--from yeast to humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Curcumin labels amyloid pathology in vivo, disrupts existing plaques, and partially restores distorted neurites in an Alzheimer mouse model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Nutrition and neurodegeneration: epidemiological evidence and challenges for future research

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Lifespan-extending caloric restriction or mTOR inhibition impair adaptive immunity of old mice by distinct mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

The effect of aging on brain barriers and the consequences for Alzheimer's disease development

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Beneficial biochemical outcomes of late-onset dietary restriction in rodents.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

An AMPK-FOXO pathway mediates longevity induced by a novel method of dietary restriction in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Calorie restriction--the SIR2 connection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Mammalian sirtuins--emerging roles in physiology, aging, and calorie restriction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Intermittent fasting and caloric restriction ameliorate age-related behavioral deficits in the triple-transgenic mouse model of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Chronic inhibition of mammalian target of rapamycin by rapamycin modulates cognitive and non-cognitive components of behavior throughout lifespan in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Caloric restriction transiently improves motor performance but hastens clinical onset of disease in the Cu/Zn-superoxide dismutase mutant G93A mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Targets for Cell Cycle Arrest by the Immunosuppressant Rapamycin in Yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Calorie restriction and methionine restriction in control of endogenous hydrogen sulfide production by the transsulfuration pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Endogenous hydrogen sulfide production is essential for dietary restriction benefits

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Caloric restriction in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Cognitive Effects of Intentional Weight Loss in Elderly Obese Individuals With Mild Cognitive Impairment

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

The resveratrol trimer miyabenol C inhibits β-secretase activity and β-amyloid generation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Resveratrol protects rats from Aβ-induced neurotoxicity by the reduction of iNOS expression and lipid peroxidation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

On the importance of fatty acid composition of membranes for aging.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Metformin, other antidiabetic drugs, and risk of Alzheimer's disease: a population-based case-control study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Dietary restriction benefits learning and motor performance of aged mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Calorie restriction mimetics: an emerging research field

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

TSC2 mediates cellular energy response to control cell growth and survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Neuroprotective role of Sirt1 in mammalian models of Huntington's disease through activation of multiple Sirt1 targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

mTOR is a key modulator of ageing and age-related disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Cellular and behavioral effects of stilbene resveratrol analogues: implications for reducing the deleterious effects of aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Atg7-dependent autophagy promotes neuronal health, stress tolerance, and longevity but is dispensable for metamorphosis in Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Eukaryotic transcription: an interlaced network of transcription factors and chromatin-modifying machines

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Regulation of lifespan in Drosophila by modulation of genes in the TOR signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Dietary supplementation with resveratrol reduces plaque pathology in a transgenic model of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

A C. elegans mutant that lives twice as long as wild type

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

SIRT1 deacetylase protects against neurodegeneration in models for Alzheimer's disease and amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Resveratrol selectively remodels soluble oligomers and fibrils of amyloid Abeta into off-pathway conformers

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

The immunosuppressant rapamycin exacerbates neurotoxicity of Abeta peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Human SIR2 deacetylates p53 and antagonizes PML/p53-induced cellular senescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Rapamycin: an anti-cancer immunosuppressant?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Dietary restriction increases the number of newly generated neural cells, and induces BDNF expression, in the dentate gyrus of rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Evidence that brain-derived neurotrophic factor is required for basal neurogenesis and mediates, in part, the enhancement of neurogenesis by dietary restriction in the hippocampus of adult mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Insulin rescues amyloid beta-induced impairment of hippocampal long-term potentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Sirt1: a metabolic master switch that modulates lifespan

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Role for DNA methylation in genomic imprinting

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Glucose restriction can extend normal cell lifespan and impair precancerous cell growth through epigenetic control of hTERT and p16 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Epigenetic regulation of caloric restriction in aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Resveratrol pretreatment attenuates the isoflurane-induced cognitive impairment through its anti-inflammation and -apoptosis actions in aged mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Chronic rapamycin restores brain vascular integrity and function through NO synthase activation and improves memory in symptomatic mice modeling Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Genome-wide analysis reveals mechanisms modulating autophagy in normal brain aging and in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Calorie restriction induces mitochondrial biogenesis and bioenergetic efficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

The epigenetic landscape of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Negative control of p53 by Sir2alpha promotes cell survival under stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Beta-amyloid oligomers induce phosphorylation of tau and inactivation of insulin receptor substrate via c-Jun N-terminal kinase signaling: suppression by omega-3 fatty acids and curcumin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Lifespan extension induced by AMPK and calcineurin is mediated by CRTC-1 and CREB

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Inducing autophagy by rapamycin before, but not after, the formation of plaques and tangles ameliorates cognitive deficits

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Resveratrol promotes clearance of Alzheimer's disease amyloid-beta peptides.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Caloric restriction mimetics: natural/physiological pharmacological autophagy inducers

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Caloric restriction and intermittent fasting: two potential diets for successful brain aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Examination of cognitive function during six months of calorie restriction: results of a randomized controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Metformin improves healthspan and lifespan in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Long live FOXO: unraveling the role of FOXO proteins in aging and longevity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

β-Amyloid regulates leptin expression and tau phosphorylation through the mTORC1 signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Overview of caloric restriction and ageing

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Caloric restriction increases neurotrophic factor levels and attenuates neurochemical and behavioral deficits in a primate model of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Brain evolution and lifespan regulation: conservation of signal transduction pathways that regulate energy metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Energy intake and exercise as determinants of brain health and vulnerability to injury and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Lifelong brain health is a lifelong challenge: from evolutionary principles to empirical evidence

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Meal size and frequency affect neuronal plasticity and vulnerability to disease: cellular and molecular mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

hEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Rapamycin, but not resveratrol or simvastatin, extends life span of genetically heterogeneous mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Rapamycin-mediated lifespan increase in mice is dose and sex dependent and metabolically distinct from dietary restriction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Autophagy: renovation of cells and tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Long-term dietary restriction modulates the level of presynaptic proteins in the cortex and hippocampus of the aging rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Caloric restriction attenuates amyloid deposition in middle-aged dtg APP/PS1 mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Epigenetic control of aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Effects of diet on brain plasticity in animal and human studies: mind the gap.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Rapamycin extends murine lifespan but has limited effects on aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Energy restriction and potential energy restriction mimetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Calorie restriction promotes mitochondrial biogenesis by inducing the expression of eNOS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Calorie restriction and prevention of age-associated chronic disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Membrane fatty acid unsaturation, protection against oxidative stress, and maximum life span: a homeoviscous-longevity adaptation?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Neuroprotective effects of dietary restriction: Evidence and mechanisms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Lessons learned from gene expression profile studies of aging and caloric restriction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Resveratrol ameliorates aging-related metabolic phenotypes by inhibiting cAMP phosphodiesterases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Metabolic syndrome and the role of dietary lifestyles in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Caloric restriction attenuates Abeta-deposition in Alzheimer transgenic models

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Clinical trials of resveratrol

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Resveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending life span

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Early etiology of Alzheimer's disease: tipping the balance toward autophagy or endosomal dysfunction?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Metabolic adaptations to methionine restriction that benefit health and lifespan in rodents

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Dietary resveratrol prevents Alzheimer's markers and increases life span in SAMP8.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

DNA microarray analysis of the aging brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

A 2-Year Randomized Controlled Trial of Human Caloric Restriction: Feasibility and Effects on Predictors of Health Span and Longevity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Caloric restriction in humans: impact on physiological, psychological, and behavioral outcomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Neurotrophin-regulated signalling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

How longevity research can lead to therapies for Alzheimer's disease: The rapamycin story

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Sir2 mediates longevity in the fly through a pathway related to calorie restriction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Brain-derived neurotrophic factor as a regulator of systemic and brain energy metabolism and cardiovascular health

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Regulation of longevity and oxidative stress by nutritional interventions: role of methionine restriction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Ammonium is a key determinant on the dietary restriction of yeast chronological aging in culture medium

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Red Wine Ingredient Resveratrol Protects from β-Amyloid Neurotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Reduction of β-amyloid and γ-secretase by calorie restriction in female Tg2576 mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Insulin receptors and insulin action in the brain: review and clinical implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Late-onset dietary restriction compensates for age-related increase in oxidative stress and alterations of HSP 70 and synapsin 1 protein levels in male Wistar rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Optimized turmeric extract reduces β-Amyloid and phosphorylated Tau protein burden in Alzheimer's transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

The mTOR Inhibitor Rapamycin Mitigates Perforant Pathway Neurodegeneration and Synapse Loss in a Mouse Model of Early-Stage Alzheimer-Type Tauopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Promoting basal levels of autophagy in the nervous system enhances longevity and oxidant resistance in adult Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Effects of the dietary approaches to stop hypertension diet, exercise, and caloric restriction on neurocognition in overweight adults with high blood pressure

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Caloric restriction and the aging process: a critique

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Oxidative stress, caloric restriction, and aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Oxidative damage, mitochondrial oxidant generation and antioxidant defenses during aging and in response to food restriction in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Inhibition of mTOR by rapamycin abolishes cognitive deficits and reduces amyloid-beta levels in a mouse model of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Emerging links between type 2 diabetes and Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Role of sirtuins and calorie restriction in neuroprotection: implications in Alzheimer's and Parkinson's diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Adenosine nucleotide biosynthesis and AMPK regulate adult life span and mediate the longevity benefit of caloric restriction in flies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

The effects of life-long food restriction on spatial memory in young and aged Fischer 344 rats measured in the eight-arm radial and the Morris water mazes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Evaluation of resveratrol, green tea extract, curcumin, oxaloacetic acid, and medium-chain triglyceride oil on life span of genetically heterogeneous mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Resveratrol: challenges in translation to the clinic--a critical discussion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

A mutant Drosophila insulin receptor homolog that extends life-span and impairs neuroendocrine function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Neuroprotective Sirtuin ratio reversed by ApoE4

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Longevity pathways converge on autophagy genes to regulate life span in Caenorhabditis elegans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Modulation of endogenous antioxidant activity by resveratrol and exercise in mouse liver is age dependent.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Organ and tissue-dependent effect of resveratrol and exercise on antioxidant defenses of old mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

A randomized, double-blind, placebo-controlled trial of resveratrol for Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Insulin signaling in the central nervous system: learning to survive

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Genetics: influence of TOR kinase on lifespan in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Cellular and molecular mechanisms of metformin: an overview

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

All about running: synaptic plasticity, growth factors and adult hippocampal neurogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Could Sirt1-mediated epigenetic effects contribute to the longevity response to dietary restriction and be mimicked by other dietary interventions?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Imatinib mesylate blocks a non-Smad TGF-beta pathway and reduces renal fibrogenesis in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

C. elegans 14-3-3 proteins regulate life span and interact with SIR-2.1 and DAF-16/FOXO.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Artemisinin mimics calorie restriction to trigger mitochondrial biogenesis and compromise telomere shortening in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Caloric restriction: powerful protection for the aging heart and vasculature.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Rapamycin slows aging in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Caloric restriction improves memory in elderly humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Effects of resveratrol on memory performance, hippocampal functional connectivity, and glucose metabolism in healthy older adults.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Transcriptome analysis in calorie-restricted rats implicates epigenetic and post-translational mechanisms in neuroprotection and aging.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Calorie restriction ameliorates neurodegenerative phenotypes in forebrain-specific presenilin-1 and presenilin-2 double knockout mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Increased mammalian lifespan and a segmental and tissue-specific slowing of aging after genetic reduction of mTOR expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Rapamycin promotes beta-amyloid production via ADAM-10 inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Rapamycin extends life and health in C57BL/6 mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Resveratrol decreases the insoluble Aβ1-42 level in hippocampus and protects the integrity of the blood-brain barrier in AD rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

mTOR inhibition activates overall protein degradation by the ubiquitin proteasome system as well as by autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Effects of diet on adenosine monophosphate-activated protein kinase activity and disease progression in an amyotrophic lateral sclerosis model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00335-016-9647-6

Effect of taurine and N-acetylcysteine on methionine restriction-mediated adiposity resistance

21 January 2018

1 reference

12 December 2020

Insulin and Alzheimer's disease: untangling the web.

1 reference

12 December 2020

Neuroprotective role of trans-resveratrol in a murine model of familial Alzheimer's disease.

1 reference

12 December 2020

Caloric restriction, caloric restriction mimetics, and healthy aging in Okinawa: controversies and clinical implications

1 reference

12 December 2020

Overexpression of Atg5 in mice activates autophagy and extends lifespan

1 reference

12 December 2020

hTERT is a critical determinant of telomerase activity in renal-cell carcinoma

1 reference

12 December 2020

Metformin supplementation and life span in Fischer-344 rats

1 reference

12 December 2020

Dietary intervention at middle age: caloric restriction but not dehydroepiandrosterone sulfate increases lifespan and lifetime cancer incidence in mice

1 reference

12 December 2020

The effect of retarded growth upon the length of life span and upon the ultimate body size. 1935

1 reference

12 December 2020

Rapamycin fed late in life extends lifespan in genetically heterogeneous mice

1 reference

12 December 2020

mTOR regulation and therapeutic rejuvenation of aging hematopoietic stem cells

1 reference

12 December 2020

Incidence of dementia is increased in type 2 diabetes and reduced by the use of sulfonylureas and metformin

1 reference

12 December 2020

Relationship between transcription and DNA methylation.

1 reference

12 December 2020

Caloric restriction attenuates beta-amyloid neuropathology in a mouse model of Alzheimer's disease

1 reference

12 December 2020

The free radical theory of aging matures

1 reference

12 December 2020

Mid-life onset of dietary restriction extends life and prolongs cognitive functioning

1 reference

12 December 2020

The curry spice curcumin reduces oxidative damage and amyloid pathology in an Alzheimer transgenic mouse.

1 reference

12 December 2020

Dietary restriction and 2-deoxyglucose administration improve behavioral outcome and reduce degeneration of dopaminergic neurons in models of Parkinson's disease.

1 reference

12 December 2020

10.1007/S00335-016-9647-6

Identifiers

DOI

1 reference

7 September 2017

1 reference

PubMed ID

27240590