(Q38849069)

English

A global RNA-seq-driven analysis of CHO host and production cell lines reveals distinct differential expression patterns of genes contributing to recombinant antibody glycosylation

scientific article published on 23 July 2015

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scholarly article

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Europe PubMed Central

PubMed publication ID

7 September 2017

A global RNA-seq-driven analysis of CHO host and production cell lines reveals distinct differential expression patterns of genes contributing to recombinant antibody glycosylation (English)

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Europe PubMed Central

PubMed publication ID

7 September 2017

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based on heuristic

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author name string

Jennifer D Könitzer

1

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Europe PubMed Central

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7 September 2017

Markus M Müller

2

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7 September 2017

Germán Leparc

3

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7 September 2017

Martin Pauers

4

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7 September 2017

Jan Bechmann

5

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7 September 2017

Patrick Schulz

6

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7 September 2017

Jochen Schaub

7

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Europe PubMed Central

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7 September 2017

Barbara Enenkel

8

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7 September 2017

Tobias Hildebrandt

9

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7 September 2017

Martin Hampel

10

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7 September 2017

Anne B Tolstrup

11

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7 September 2017

publication date

23 July 2015

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7 September 2017

Biotechnology Journal

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7 September 2017

10

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7 September 2017

9

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7 September 2017

1412-1423

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7 September 2017

The N-linked sugar chains of human immunoglobulin G: their unique pattern, and their functional roles

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400652

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The current status and prospects of antibody engineering for therapeutic use: focus on glycoengineering technology

1 reference

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Glycans in the immune system and The Altered Glycan Theory of Autoimmunity: a critical review

1 reference

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IgG-Fc N-glycosylation at Asn297 and IgA O-glycosylation in the hinge region in health and disease

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Characterization and comparison of commercially available TNF receptor 2-Fc fusion protein products

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Physicochemical and functional comparability between the proposed biosimilar rituximab GP2013 and originator rituximab

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Biosimilars: are they bioequivalent?

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Obinutuzumab: first global approval

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Marketing approval of mogamulizumab: a triumph for glyco-engineering

1 reference

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The genomic sequence of the Chinese hamster ovary (CHO)-K1 cell line

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400652

21 January 2018

Chinese hamster genome database: an online resource for the CHO community at www.CHOgenome.org

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400652

21 January 2018

Deglycosylation of asparagine-linked glycans by peptide:N-glycosidase F.

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400652

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Nonselective and efficient fluorescent labeling of glycans using 2-amino benzamide and anthranilic acid

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400652

21 January 2018

Into the unknown: expression profiling without genome sequence information in CHO by next generation sequencing

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400652

21 January 2018

Search and clustering orders of magnitude faster than BLAST

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400652

21 January 2018

STAR: ultrafast universal RNA-seq aligner

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400652

21 January 2018

Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400652

21 January 2018

RNA-SeQC: RNA-seq metrics for quality control and process optimization

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400652

21 January 2018

Mapping and quantifying mammalian transcriptomes by RNA-Seq

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400652

21 January 2018

An abundance of ubiquitously expressed genes revealed by tissue transcriptome sequence data

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400652

21 January 2018

Isolation of Chinese hamster cell mutants deficient in dihydrofolate reductase activity

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400652

21 January 2018

Amino acid and glucose metabolism in fed-batch CHO cell culture affects antibody production and glycosylation

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400652

21 January 2018

CHO cell line specific prediction and control of recombinant monoclonal antibody N-glycosylation

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400652

21 January 2018

Optimal and consistent protein glycosylation in mammalian cell culture

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400652

21 January 2018

Evaluating the impact of cell culture process parameters on monoclonal antibody N-glycosylation

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400652

21 January 2018

Glycosylation of recombinant antibody therapeutics

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400652

21 January 2018

Industry and regulatory experience of the glycosylation of monoclonal antibodies

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400652

21 January 2018

With or without sugar? (A)glycosylation of therapeutic antibodies

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400652

21 January 2018

Impact of differential glycosylation on IgG activity

1 reference

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21 January 2018

Quantitative evaluation of fucose reducing effects in a humanized antibody on Fcγ receptor binding and antibody-dependent cell-mediated cytotoxicity activities

1 reference

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21 January 2018

Two mechanisms of the enhanced antibody-dependent cellular cytotoxicity (ADCC) efficacy of non-fucosylated therapeutic antibodies in human blood

1 reference

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21 January 2018

Non-fucosylated therapeutic antibodies: the next generation of therapeutic antibodies

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400652

21 January 2018

Antibody fucosylation differentially impacts cytotoxicity mediated by NK and PMN effector cells

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400652

21 January 2018

Production, characterization, and pharmacokinetic properties of antibodies with N-linked mannose-5 glycans

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400652

21 January 2018

Agalactosyl glycoforms of IgG autoantibodies are pathogenic

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400652

21 January 2018

The absence of fucose but not the presence of galactose or bisecting N-acetylglucosamine of human IgG1 complex-type oligosaccharides shows the critical role of enhancing antibody-dependent cellular cytotoxicity

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400652

21 January 2018

Genomic landscapes of Chinese hamster ovary cell lines as revealed by the Cricetulus griseus draft genome

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400652

21 January 2018

Intraclonal protein expression heterogeneity in recombinant CHO cells

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400652

21 January 2018

Molecular analysis of three gain-of-function CHO mutants that add the bisecting GlcNAc to N-glycans

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400652

21 January 2018

Production platforms for biotherapeutic glycoproteins. Occurrence, impact, and challenges of non-human sialylation

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400652

21 January 2018

Fluorescence in situ hybridization using bacterial artificial chromosome (BAC) clones for the analysis of chromosome rearrangement in Chinese hamster ovary cells.

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400652

21 January 2018

Identifiers

10.1002/BIOT.201400652

1 reference

Europe PubMed Central

PubMed publication ID

7 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

7 September 2017

ResearchGate publication ID

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