(Q38852640)

7 September 2017

title

PBRM1 (BAF180) protein is functionally regulated by p53-induced protein degradation in renal cell carcinomas (English)

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7 September 2017

9

Markus Hohenfellner

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7 September 2017

7

Sascha Pahernik

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7 September 2017

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Wilfried Roth

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7 September 2017

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Stefan Duensing

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Stephan Macher-Goeppinger

7 September 2017

1

object named as

Stephan Macher-Goeppinger

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7 September 2017

2

Martina Keith

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7 September 2017

3

Katrin E Tagscherer

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7 September 2017

Stephan Singer

4

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7 September 2017

Juliane Winkler

5

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7 September 2017

Thomas G Hofmann

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7 September 2017

Juergen Kopitz

10

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7 September 2017

Peter Schirmacher

11

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7 September 2017

publication date

16 July 2015

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7 September 2017

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7 September 2017

volume

237

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7 September 2017

issue

4

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7 September 2017

page(s)

460-471

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Identification of the von Hippel-Lindau disease tumor suppressor gene

7 September 2017

cites work

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p53 pathway in renal cell carcinoma is repressed by a dominant mechanism.

21 January 2018

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Combined p53 and MDM2 biomarker analysis shows a unique pattern of expression associated with poor prognosis in patients with renal cell carcinoma undergoing radical nephrectomy.

21 January 2018

1 reference

p53 and MDM2 in renal cell carcinoma: biomarkers for disease progression and future therapeutic targets?

21 January 2018

1 reference

The von Hippel-Lindau tumor suppressor gene and kidney cancer

21 January 2018

1 reference

Systematic sequencing of renal carcinoma reveals inactivation of histone modifying genes

21 January 2018

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Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma

21 January 2018

1 reference

Polybromo-1: the chromatin targeting subunit of the PBAF complex

21 January 2018

1 reference

BAP1 loss defines a new class of renal cell carcinoma

21 January 2018

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Somatic mutations of the histone H3K27 demethylase gene UTX in human cancer

21 January 2018

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Polybromo-associated BRG1-associated factor components BRD7 and BAF180 are critical regulators of p53 required for induction of replicative senescence

21 January 2018

1 reference

BAF180 is a critical regulator of p21 induction and a tumor suppressor mutated in breast cancer

21 January 2018

1 reference

High-throughput SNP-based authentication of human cell lines

21 January 2018

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High-throughput detection and multiplex identification of cell contaminations

21 January 2018

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p53-dependent regulation of Mcl-1 contributes to synergistic cell death by ionizing radiation and the Bcl-2/Bcl-XL inhibitor ABT-737.

21 January 2018

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Nuclear pore component Nup98 is a potential tumor suppressor and regulates posttranscriptional expression of select p53 target genes

21 January 2018

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The soluble Decoy Receptor 3 is regulated by a PI3K-dependent mechanism and promotes migration and invasion in renal cell carcinoma

21 January 2018

1 reference

Notch1 signaling promotes survival of glioblastoma cells via EGFR-mediated induction of anti-apoptotic Mcl-1.

21 January 2018

1 reference

Loss of PBRM1 expression is associated with renal cell carcinoma progression

21 January 2018

1 reference

Comprehensive molecular characterization of clear cell renal cell carcinoma

21 January 2018

1 reference

The cBio cancer genomics portal: an open platform for exploring multidimensional cancer genomics data

21 January 2018

1 reference

Integrative analysis of complex cancer genomics and clinical profiles using the cBioPortal

21 January 2018

1 reference

Siah-1 mediates a novel beta-catenin degradation pathway linking p53 to the adenomatous polyposis coli protein

21 January 2018

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SIAH-1 promotes apoptosis and tumor suppression through a network involving the regulation of protein folding, unfolding, and trafficking: identification of common effectors with p53 and p21(Waf1)

21 January 2018

1 reference

21 January 2018

MDM2: life without p53.

1 reference

Direct, activating interaction between glycogen synthase kinase-3beta and p53 after DNA damage

21 January 2018

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Lithium stabilizes the CCAAT/enhancer-binding protein alpha (C/EBPalpha) through a glycogen synthase kinase 3 (GSK3)-independent pathway involving direct inhibition of proteasomal activity

21 January 2018

1 reference

Inhibitors of ubiquitin-activating enzyme (E1), a new class of potential cancer therapeutics.

21 January 2018

1 reference

Diversity and specialization of mammalian SWI/SNF complexes

21 January 2018

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The SWI/SNF complex and cancer

21 January 2018

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Exome sequencing identifies frequent inactivating mutations in BAP1, ARID1A and PBRM1 in intrahepatic cholangiocarcinomas

21 January 2018

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Whole-exome sequencing of human pancreatic cancers and characterization of genomic instability caused by MLH1 haploinsufficiency and complete deficiency

21 January 2018

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Wnt signaling controls the phosphorylation status of beta-catenin.

21 January 2018

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The Mdm2-p53 relationship evolves: Mdm2 swings both ways as an oncogene and a tumor suppressor

21 January 2018

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Remodelling chromatin on a global scale: a novel protective function of p53.

21 January 2018

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p53, the cellular gatekeeper for growth and division

21 January 2018

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The dark side of a tumor suppressor: anti-apoptotic p53.

21 January 2018

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Control of HIPK2 stability by ubiquitin ligase Siah-1 and checkpoint kinases ATM and ATR.

21 January 2018

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Epigenetics in cancer: targeting chromatin modifications

21 January 2018

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Epigenetics: judge, jury and executioner of stem cell fate.

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/PATH.4592

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7 September 2017

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