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Chemical probes of quorum sensing: from compound development to biological discovery
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Europe PubMed Central
PMCID
5007280
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27268906%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 March 2020
review article
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Europe PubMed Central
title
Chemical probes of quorum sensing: from compound development to biological discovery
(English)
1 reference
stated in
Europe PubMed Central
PMCID
5007280
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27268906%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 March 2020
main subject
quorum sensing
0 references
author
Michael A Welsh
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMCID
5007280
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27268906%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 March 2020
Helen Blackwell
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2
object named as
Helen E Blackwell
1 reference
stated in
Europe PubMed Central
PMCID
5007280
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27268906%20AND%20SRC:MED&resulttype=core&format=json
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12 March 2020
publication date
5 June 2016
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Europe PubMed Central
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5007280
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27268906%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 March 2020
published in
FEMS Microbiology Reviews
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Europe PubMed Central
PMCID
5007280
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27268906%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 March 2020
volume
40
1 reference
stated in
Europe PubMed Central
PMCID
5007280
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27268906%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 March 2020
issue
5
1 reference
stated in
Europe PubMed Central
PMCID
5007280
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27268906%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 March 2020
page(s)
774-794
1 reference
stated in
Europe PubMed Central
PMCID
5007280
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27268906%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 March 2020
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Quorum Sensing Is Accompanied by Global Metabolic Changes in the Opportunistic Human Pathogen Pseudomonas aeruginosa
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Small molecule disruption of quorum sensing cross-regulation in pseudomonas aeruginosa causes major and unexpected alterations to virulence phenotypes
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The hierarchy quorum sensing network in Pseudomonas aeruginosa
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Mutational analysis of the quorum-sensing receptor LasR reveals interactions that govern activation and inhibition by nonlactone ligands
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Identification of anti-virulence compounds that disrupt quorum-sensing regulated acute and persistent pathogenicity
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Competition studies confirm two major barriers that can preclude the spread of resistance to quorum-sensing inhibitors in bacteria
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Selective chemical inhibition of agr quorum sensing in Staphylococcus aureus promotes host defense with minimal impact on resistance
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Structural insights into the molecular mechanism of Escherichia coli SdiA, a quorum-sensing receptor
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Resistance to quorum-quenching compounds
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9 September 2017
Identification of five structurally unrelated quorum-sensing inhibitors of Pseudomonas aeruginosa from a natural-derivative database
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Structural basis for native agonist and synthetic inhibitor recognition by the Pseudomonas aeruginosa quorum sensing regulator PqsR (MvfR)
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9 September 2017
A high-throughput screen for quorum-sensing inhibitors that target acyl-homoserine lactone synthases
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Quo vadis quorum quenching?
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Synthesis and biological evaluation of triazole-containing N-acyl homoserine lactones as quorum sensing modulators
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A dynamic and intricate regulatory network determines Pseudomonas aeruginosa virulence
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Bacterial quorum sensing: its role in virulence and possibilities for its control
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Inhibition of the production of the Pseudomonas aeruginosa virulence factor pyocyanin in wild-type cells by quorum sensing autoinducer-mimics
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9 September 2017
Validation of PqsD as an anti-biofilm target in Pseudomonas aeruginosa by development of small-molecule inhibitors
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9 September 2017
Applications of small molecule activators and inhibitors of quorum sensing in Gram-negative bacteria
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9 September 2017
Identification of small-molecule antagonists of the Pseudomonas aeruginosa transcriptional regulator PqsR: biophysically guided hit discovery and optimization
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9 September 2017
Inhibition of biofilm formation, quorum sensing and infection in Pseudomonas aeruginosa by natural products-inspired organosulfur compounds
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9 September 2017
AI-2-mediated signalling in bacteria
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9 September 2017
Honaucins A-C, potent inhibitors of inflammation and bacterial quorum sensing: synthetic derivatives and structure-activity relationships
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9 September 2017
Pseudomonas aeruginosa RhlR is required to neutralize the cellular immune response in a Drosophila melanogaster oral infection model
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9 September 2017
Isovaleryl-homoserine lactone, an unusual branched-chain quorum-sensing signal from the soybean symbiont Bradyrhizobium japonicum
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9 September 2017
Quorum quenching quandary: resistance to antivirulence compounds
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9 September 2017
Crystal structure of QscR, a Pseudomonas aeruginosa quorum sensing signal receptor
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9 September 2017
Design, synthesis, and biological evaluation of abiotic, non-lactone modulators of LuxR-type quorum sensing
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9 September 2017
Thiolactone modulators of quorum sensing revealed through library design and screening
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9 September 2017
Small-molecule inhibitor binding to an N-acyl-homoserine lactone synthase
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9 September 2017
Chemical genetics
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9 September 2017
A Strategy for Antagonizing Quorum Sensing
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9 September 2017
Potent and selective synthetic modulators of a quorum sensing repressor in Pseudomonas aeruginosa identified from second-generation libraries of N-acylated L-homoserine lactones
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9 September 2017
Lyngbyoic acid, a "tagged" fatty acid from a marine cyanobacterium, disrupts quorum sensing in Pseudomonas aeruginosa
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9 September 2017
Quorum sensing in Gram-negative bacteria: small-molecule modulation of AHL and AI-2 quorum sensing pathways
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9 September 2017
Peptide signaling in the staphylococci
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9 September 2017
Quorum sensing in bacterial species that use degenerate autoinducers can be tuned by using structurally identical non-native ligands.
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9 September 2017
Structural basis of acyl-homoserine lactone-dependent signaling
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PubMed Central
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9 September 2017
Surface-mediated release of a synthetic small-molecule modulator of bacterial quorum sensing: gradual release enhances activity
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9 September 2017
Quinolones: from antibiotics to autoinducers
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007280
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9 September 2017
Molecular Basis for the Recognition of Structurally Distinct Autoinducer Mimics by the Pseudomonas aeruginosa LasR Quorum-Sensing Signaling Receptor
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007280
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9 September 2017
Bacterial quorum-sensing network architectures
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007280
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9 September 2017
A quorum-sensing antagonist targets both membrane-bound and cytoplasmic receptors and controls bacterial pathogenicity
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007280
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9 September 2017
Transition state analogs of 5'-methylthioadenosine nucleosidase disrupt quorum sensing
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007280
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9 September 2017
Orphan LuxR regulators of quorum sensing
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007280
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9 September 2017
Structure and function of the LysR-type transcriptional regulator (LTTR) family proteins
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007280
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9 September 2017
Evaluation of a focused library of N-aryl L-homoserine lactones reveals a new set of potent quorum sensing modulators
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007280
retrieved
9 September 2017
The influence of iron on Pseudomonas aeruginosa physiology: a regulatory link between iron and quorum sensing
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007280
retrieved
9 September 2017
Inhibitors of pathogen intercellular signals as selective anti-infective compounds
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007280
retrieved
9 September 2017
Targeting virulence: a new paradigm for antimicrobial therapy
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007280
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9 September 2017
Chemical biology of steroid and nuclear hormone receptors
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007280
retrieved
9 September 2017
A structurally unrelated mimic of a Pseudomonas aeruginosa acyl-homoserine lactone quorum-sensing signal.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007280
retrieved
9 September 2017
Novel Pseudomonas aeruginosa quorum-sensing inhibitors identified in an ultra-high-throughput screen.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007280
retrieved
9 September 2017
Bacterially speaking
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007280
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9 September 2017
Regulation of quorum sensing in Pseudomonas
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007280
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9 September 2017
Pathogen-host interactions in Pseudomonas aeruginosa pneumonia
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007280
retrieved
9 September 2017
Library screening for synthetic agonists and antagonists of a Pseudomonas aeruginosa autoinducer
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007280
retrieved
9 September 2017
Quorum sensing in plant-pathogenic bacteria
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007280
retrieved
9 September 2017
Induction and inhibition of Pseudomonas aeruginosa quorum sensing by synthetic autoinducer analogs
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007280
retrieved
9 September 2017
Functions required for extracellular quinolone signaling by Pseudomonas aeruginosa
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007280
retrieved
9 September 2017
Listening in on bacteria: acyl-homoserine lactone signalling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007280
retrieved
9 September 2017
The crystal structure of the quorum sensing protein TraR bound to its autoinducer and target DNA
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007280
retrieved
9 September 2017
Structure of a bacterial quorum-sensing transcription factor complexed with pheromone and DNA
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007280
retrieved
9 September 2017
Regulation of gene expression by cell-to-cell communication: acyl-homoserine lactone quorum sensing
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007280
retrieved
9 September 2017
Interference with Pseudomonas quinolone signal synthesis inhibits virulence factor expression by Pseudomonas aeruginosa
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007280
retrieved
9 September 2017
Unnatural ligands for engineered proteins: new tools for chemical genetics
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007280
retrieved
9 September 2017
Acyl homoserine-lactone quorum-sensing signal generation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007280
retrieved
9 September 2017
Active efflux and diffusion are involved in transport of Pseudomonas aeruginosa cell-to-cell signals
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007280
retrieved
9 September 2017
Biochemical and biophysical analysis of a chiral PqsD inhibitor revealing tight-binding behavior and enantiomers with contrary thermodynamic signatures
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007280
retrieved
9 September 2017
Discovery and biophysical characterization of 2-amino-oxadiazoles as novel antagonists of PqsR, an important regulator of Pseudomonas aeruginosa virulence
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007280
retrieved
9 September 2017
Analogs of the autoinducer 3-oxooctanoyl-homoserine lactone strongly inhibit activity of the TraR protein of Agrobacterium tumefaciens.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007280
retrieved
14 September 2017
Fimbrolide Natural Products Disrupt Bioluminescence of Vibrio By Targeting Autoinducer Biosynthesis and Luciferase Activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007280
retrieved
14 September 2017
Application of Dual Inhibition Concept within Looped Autoregulatory Systems toward Antivirulence Agents against Pseudomonas aeruginosa Infections
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007280
retrieved
25 September 2017
A Comparative Analysis of Acyl-Homoserine Lactone Synthase Assays
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007280
retrieved
25 September 2017
PqsE of Pseudomonas aeruginosa Acts as Pathway-Specific Thioesterase in the Biosynthesis of Alkylquinolone Signaling Molecules.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007280
retrieved
25 September 2017
RhlR expression in Pseudomonas aeruginosa is modulated by the Pseudomonas quinolone signal via PhoB-dependent and -independent pathways.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007280
retrieved
25 September 2017
Exploring the chemical space of ureidothiophene-2-carboxylic acids as inhibitors of the quorum sensing enzyme PqsD from Pseudomonas aeruginosa
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007280
retrieved
25 September 2017
Triazole-containing N-acyl homoserine lactones targeting the quorum sensing system in Pseudomonas aeruginosa
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007280
retrieved
17 June 2018
The Crc protein participates in down-regulation of the Lon gene to promote rhamnolipid production and rhl quorum sensing in Pseudomonas aeruginosa.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007280
retrieved
17 June 2018
Catechol-based substrates of chalcone synthase as a scaffold for novel inhibitors of PqsD.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007280
retrieved
17 June 2018
The social biology of quorum sensing in a naturalistic host pathogen system
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007280
retrieved
17 June 2018
Crystallization and preliminary crystal structure analysis of the ligand-binding domain of PqsR (MvfR), the Pseudomonas quinolone signal (PQS) responsive quorum-sensing transcription factor of Pseudomonas aeruginosa
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007280
retrieved
17 June 2018
Purification, crystallization and preliminary X-ray diffraction analysis of the C-terminal fragment of the MvfR protein from Pseudomonas aeruginosa
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007280
retrieved
17 June 2018
Synthesis and molecular modeling provide insight into a Pseudomonas aeruginosa quorum sensing conundrum
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007280
retrieved
17 June 2018
Acyl-homoserine lactone binding to and stability of the orphan Pseudomonas aeruginosa quorum-sensing signal receptor QscR.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007280
retrieved
17 June 2018
Small molecules that modulate quorum sensing and control virulence in Pseudomonas aeruginosa
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007280
retrieved
17 June 2018
Evidence that halogenated furanones from Delisea pulchra inhibit acylated homoserine lactone (AHL)-mediated gene expression by displacing the AHL signal from its receptor protein.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007280
retrieved
17 June 2018
Editorial: LuxR Solos are Becoming Major Players in Cell-Cell Communication in Bacteria.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007280
retrieved
22 August 2018
Census of solo LuxR genes in prokaryotic genomes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007280
retrieved
22 August 2018
Potent Irreversible Inhibitors of LasR Quorum Sensing in Pseudomonas aeruginosa
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007280
retrieved
22 August 2018
Optimization of anti-virulence PqsR antagonists regarding aqueous solubility and biological properties resulting in new insights in structure-activity relationships.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007280
retrieved
22 August 2018
Overcoming the unexpected functional inversion of a PqsR antagonist in Pseudomonas aeruginosa: an in vivo potent antivirulence agent targeting pqs quorum sensing
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007280
retrieved
22 August 2018
Combining in silico and biophysical methods for the development of Pseudomonas aeruginosa quorum sensing inhibitors: an alternative approach for structure-based drug design
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007280
retrieved
22 August 2018
Tailor-made LasR agonists modulate quorum sensing in Pseudomonas aeruginosa
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007280
retrieved
22 August 2018
Structure optimization of 2-benzamidobenzoic acids as PqsD inhibitors for Pseudomonas aeruginosa infections and elucidation of binding mode by SPR, STD NMR, and molecular docking
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007280
retrieved
22 August 2018
A cell-cell communication signal integrates quorum sensing and stress response
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007280
retrieved
22 August 2018
Chemical methods to interrogate bacterial quorum sensing pathways
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007280
retrieved
22 August 2018
Design, synthesis and biological evaluation of non-natural modulators of quorum sensing in Pseudomonas aeruginosa.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007280
retrieved
22 August 2018
Discovery of antagonists of PqsR, a key player in 2-alkyl-4-quinolone-dependent quorum sensing in Pseudomonas aeruginosa.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007280
retrieved
22 August 2018
Live cell labeling of native intracellular bacterial receptors using aniline-catalyzed oxime ligation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007280
retrieved
22 August 2018
Reversible signal binding by the Pseudomonas aeruginosa quorum-sensing signal receptor LasR.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007280
retrieved
22 August 2018
Covalent inhibition of bacterial quorum sensing.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007280
retrieved
22 August 2018
Revisiting the quorum-sensing hierarchy in Pseudomonas aeruginosa: the transcriptional regulator RhlR regulates LasR-specific factors.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007280
retrieved
22 August 2018
A new class of homoserine lactone quorum-sensing signals.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007280
retrieved
22 August 2018
The LuxR receptor: the sites of interaction with quorum-sensing signals and inhibitors.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007280
retrieved
22 August 2018
Synthesis and stability of small molecule probes for Pseudomonas aeruginosa quorum sensing modulation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007280
retrieved
22 August 2018
Inhibition of quorum sensing in Pseudomonas aeruginosa biofilm bacteria by a halogenated furanone compound.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007280
retrieved
22 August 2018
An acyl-SAM analog as an affinity ligand for identifying quorum sensing signal synthases
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/27268906
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Benzamidobenzoic acids as potent PqsD inhibitors for the treatment of Pseudomonas aeruginosa infections
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/27268906
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
From in vitro to in cellulo: structure-activity relationship of (2-nitrophenyl)methanol derivatives as inhibitors of PqsD in Pseudomonas aeruginosa
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/27268906
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Targeting virulence: can we make evolution-proof drugs?
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/27268906
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Biosynthesis of 2-Alkyl-4(1H)-Quinolones in Pseudomonas aeruginosa: Potential for Therapeutic Interference with Pathogenicity
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/27268906
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1093/FEMSRE/FUW009
1 reference
stated in
Europe PubMed Central
PMCID
5007280
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27268906%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 March 2020
PMCID
5007280
1 reference
stated in
Europe PubMed Central
PMCID
5007280
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27268906%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 March 2020
PubMed ID
27268906
1 reference
stated in
Europe PubMed Central
PMCID
5007280
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27268906%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 March 2020
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