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Antigenic landscape of the HIV-1 envelope and new immunological concepts defined by HIV-1 broadly neutralizing antibodies.
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Europe PubMed Central
PMC publication ID
5086270
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27289425%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 March 2020
review article
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Europe PubMed Central
title
Antigenic landscape of the HIV-1 envelope and new immunological concepts defined by HIV-1 broadly neutralizing antibodies
(English)
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stated in
Europe PubMed Central
PMC publication ID
5086270
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27289425%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 March 2020
main subject
HIV
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author
Xiang-Peng Kong
series ordinal
2
1 reference
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Europe PubMed Central
PMC publication ID
5086270
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27289425%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 March 2020
author name string
Xueling Wu
series ordinal
1
1 reference
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Europe PubMed Central
PMC publication ID
5086270
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27289425%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 March 2020
publication date
10 June 2016
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Europe PubMed Central
PMC publication ID
5086270
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27289425%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 March 2020
published in
Current Opinion in Immunology
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stated in
Europe PubMed Central
PMC publication ID
5086270
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27289425%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 March 2020
volume
42
1 reference
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Europe PubMed Central
PMC publication ID
5086270
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27289425%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 March 2020
page(s)
56-64
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Europe PubMed Central
PMC publication ID
5086270
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27289425%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 March 2020
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Maturation and Diversity of the VRC01-Antibody Lineage over 15 Years of Chronic HIV-1 Infection
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17 June 2018
Antibody 8ANC195 Reveals a Site of Broad Vulnerability on the HIV-1 Envelope Spike
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A next-generation cleaved, soluble HIV-1 Env trimer, BG505 SOSIP.664 gp140, expresses multiple epitopes for broadly neutralizing but not non-neutralizing antibodies
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Multidonor Analysis Reveals Structural Elements, Genetic Determinants, and Maturation Pathway for HIV-1 Neutralization by VRC01-Class Antibodies
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Structural basis for diverse N-glycan recognition by HIV-1–neutralizing V1–V2–directed antibody PG16
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17 June 2018
Supersite of immune vulnerability on the glycosylated face of HIV-1 envelope glycoprotein gp120
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17 June 2018
Delineating antibody recognition in polyclonal sera from patterns of HIV-1 isolate neutralization
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17 June 2018
Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus
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17 June 2018
Harnessing CD4⁺ T cell responses in HIV vaccine development
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17 June 2018
Vaccine Induction of Antibodies against a Structurally Heterogeneous Site of Immune Pressure within HIV-1 Envelope Protein Variable Regions 1 and 2
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17 June 2018
Recombinant HIV envelope proteins fail to engage germline versions of anti-CD4bs bNAbs
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17 June 2018
Broad and potent neutralization of HIV-1 by a gp41-specific human antibody
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17 June 2018
Most rhesus macaques infected with the CCR5-tropic SHIV(AD8) generate cross-reactive antibodies that neutralize multiple HIV-1 strains
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17 June 2018
Evolution of an HIV glycan-dependent broadly neutralizing antibody epitope through immune escape
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17 June 2018
A Blueprint for HIV Vaccine Discovery
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17 June 2018
Characterization of human IgG repertoires in an acute HIV-1 infection
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17 June 2018
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17 June 2018
Broad neutralization by a combination of antibodies recognizing the CD4 binding site and a new conformational epitope on the HIV-1 envelope protein
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17 June 2018
Broadly neutralizing antibodies present new prospects to counter highly antigenically diverse viruses
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17 June 2018
Structural basis for germ-line gene usage of a potent class of antibodies targeting the CD4-binding site of HIV-1 gp120.
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17 June 2018
Human peripheral blood antibodies with long HCDR3s are established primarily at original recombination using a limited subset of germline genes
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17 June 2018
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17 June 2018
Characterization of germline antibody libraries from human umbilical cord blood and selection of monoclonal antibodies to viral envelope glycoproteins: Implications for mechanisms of immune evasion and design of vaccine immunogens
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17 June 2018
Rapid development of glycan-specific, broad, and potent anti-HIV-1 gp120 neutralizing antibodies in an R5 SIV/HIV chimeric virus infected macaque
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17 June 2018
Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9
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17 June 2018
H3N2 influenza infection elicits more cross-reactive and less clonally expanded anti-hemagglutinin antibodies than influenza vaccination
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17 June 2018
Antibody mechanics on a membrane-bound HIV segment essential for GP41-targeted viral neutralization
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17 June 2018
A Potent and Broad Neutralizing Antibody Recognizes and Penetrates the HIV Glycan Shield
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17 June 2018
Broad neutralization coverage of HIV by multiple highly potent antibodies
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PubMed Central
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17 June 2018
Focused Evolution of HIV-1 Neutralizing Antibodies Revealed by Structures and Deep Sequencing
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PubMed Central
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17 June 2018
Analysis of a clonal lineage of HIV-1 envelope V2/V3 conformational epitope-specific broadly neutralizing antibodies and their inferred unmutated common ancestors
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PubMed Central
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17 June 2018
Sequence and Structural Convergence of Broad and Potent HIV Antibodies That Mimic CD4 Binding
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PubMed Central
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17 June 2018
Rational design of envelope identifies broadly neutralizing human monoclonal antibodies to HIV-1
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17 June 2018
Structural Basis for Broad and Potent Neutralization of HIV-1 by Antibody VRC01
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5086270
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17 June 2018
Analysis of memory B cell responses and isolation of novel monoclonal antibodies with neutralizing breadth from HIV-1-infected individuals
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5086270
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17 June 2018
Structural Basis of Immune Evasion at the Site of CD4 Attachment on HIV-1 gp120
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PubMed Central
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17 June 2018
Vaccination with ALVAC and AIDSVAX to prevent HIV-1 infection in Thailand
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PubMed Central
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17 June 2018
Germline-like predecessors of broadly neutralizing antibodies lack measurable binding to HIV-1 envelope glycoproteins: implications for evasion of immune responses and design of vaccine immunogens
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5086270
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17 June 2018
Broad and potent neutralizing antibodies from an African donor reveal a new HIV-1 vaccine target
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5086270
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17 June 2018
The membrane-proximal external region of the human immunodeficiency virus type 1 envelope: dominant site of antibody neutralization and target for vaccine design
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5086270
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17 June 2018
Structural definition of a conserved neutralization epitope on HIV-1 gp120
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5086270
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17 June 2018
Cardiolipin polyspecific autoreactivity in two broadly neutralizing HIV-1 antibodies.
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5086270
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17 June 2018
Broadly neutralizing anti-HIV antibody 4E10 recognizes a helical conformation of a highly conserved fusion-associated motif in gp41
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5086270
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17 June 2018
Structure and mechanistic analysis of the anti-human immunodeficiency virus type 1 antibody 2F5 in complex with its gp41 epitope
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PubMed Central
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17 June 2018
Predominant autoantibody production by early human B cell precursors
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PubMed Central
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17 June 2018
Antibody domain exchange is an immunological solution to carbohydrate cluster recognition
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PubMed Central
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17 June 2018
A potent cross-clade neutralizing human monoclonal antibody against a novel epitope on gp41 of human immunodeficiency virus type 1.
1 reference
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PubMed Central
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17 June 2018
Broadly neutralizing antibodies targeted to the membrane-proximal external region of human immunodeficiency virus type 1 glycoprotein gp41.
1 reference
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PubMed Central
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17 June 2018
Immunoglobulin heavy chain expression shapes the B cell receptor repertoire in human B cell development
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5086270
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17 June 2018
Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5086270
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17 June 2018
A role for carbohydrates in immune evasion in AIDS.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5086270
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17 June 2018
A model for induction of T cell-independent humoral immunity in response to polysaccharide antigens.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5086270
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17 June 2018
Efficient neutralization of primary isolates of HIV-1 by a recombinant human monoclonal antibody
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5086270
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17 June 2018
A broadly neutralizing human monoclonal antibody against gp41 of human immunodeficiency virus type 1.
1 reference
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17 June 2018
T cell-independent antigens type 2.
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17 June 2018
Generation of Human Monoclonal Antibodies against HIV-1 Proteins; Electrofusion and Epstein-Barr Virus Transformation for Peripheral Blood Lymphocyte Immortalization
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5086270
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17 June 2018
Levels of somatic hypermutations in B cell receptors increase during childhood.
1 reference
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5086270
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22 August 2018
Limits for antibody affinity maturation and repertoire diversification in hypervaccinated humans
1 reference
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22 August 2018
Progress in HIV-1 vaccine development
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22 August 2018
Identifiers
DOI
10.1016/J.COI.2016.05.013
1 reference
stated in
Europe PubMed Central
PMC publication ID
5086270
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27289425%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 March 2020
PMC publication ID
5086270
1 reference
stated in
Europe PubMed Central
PMC publication ID
5086270
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27289425%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 March 2020
PubMed publication ID
27289425
1 reference
stated in
Europe PubMed Central
PMC publication ID
5086270
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27289425%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 March 2020
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