(Q38900579)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27428307%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

review article

1 reference

title

Metabolic regulation of stem cell function in tissue homeostasis and organismal ageing (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27428307%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

1 reference

0 references

Navdeep S Chandel

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27428307%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

Theodore T Ho

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27428307%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

publication date

18 July 2016

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27428307%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27428307%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

volume

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27428307%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

issue

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27428307%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

page(s)

823-832

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27428307%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/ncb3385

18 March 2020

exact match

0 references

1 reference

Stem cell metabolism in tissue development and aging

21 January 2018

1 reference

Surviving change: the metabolic journey of hematopoietic stem cells.

21 January 2018

1 reference

Metabolic plasticity in stem cell homeostasis and differentiation

21 January 2018

1 reference

Metabolic regulation in pluripotent stem cells during reprogramming and self-renewal

21 January 2018

1 reference

Mitochondrial regulation in pluripotent stem cells

21 January 2018

1 reference

Pluripotent stem cell energy metabolism: an update

21 January 2018

1 reference

Dynamic changes in mitochondrial biogenesis and antioxidant enzymes during the spontaneous differentiation of human embryonic stem cells

21 January 2018

1 reference

The permeability transition pore controls cardiac mitochondrial maturation and myocyte differentiation.

21 January 2018

1 reference

Mitochondrial complex III ROS regulate adipocyte differentiation

21 January 2018

1 reference

Somatic oxidative bioenergetics transitions into pluripotency-dependent glycolysis to facilitate nuclear reprogramming.

21 January 2018

1 reference

UCP2 regulates energy metabolism and differentiation potential of human pluripotent stem cells.

21 January 2018

1 reference

Mitochondrial DNA replication during differentiation of murine embryonic stem cells

21 January 2018

1 reference

Growth factor erv1-like modulates Drp1 to preserve mitochondrial dynamics and function in mouse embryonic stem cells

21 January 2018

1 reference

Mitochondrial fusion by pharmacological manipulation impedes somatic cell reprogramming to pluripotency: new insight into the role of mitophagy in cell stemness

21 January 2018

1 reference

Mitofusins deficiency elicits mitochondrial metabolic reprogramming to pluripotency

21 January 2018

1 reference

Influence of metabolism on epigenetics and disease

21 January 2018

1 reference

Dependence of mouse embryonic stem cells on threonine catabolism

21 January 2018

1 reference

The metabolome regulates the epigenetic landscape during naive-to-primed human embryonic stem cell transition

21 January 2018

1 reference

Molecular regulation of stem cell quiescence.

21 January 2018

1 reference

Stem cells, ageing and the quest for immortality.

21 January 2018

1 reference

Stems cells and the pathways to aging and cancer

21 January 2018

1 reference

21 January 2018

The hallmarks of aging

1 reference

Aging-Induced Stem Cell Mutations as Drivers for Disease and Cancer

21 January 2018

1 reference

Cell cycle regulation in hematopoietic stem cells

21 January 2018

1 reference

The distinct metabolic profile of hematopoietic stem cells reflects their location in a hypoxic niche.

21 January 2018

1 reference

Regulation of glycolysis by Pdk functions as a metabolic checkpoint for cell cycle quiescence in hematopoietic stem cells

21 January 2018

1 reference

Metabolic regulation by the mitochondrial phosphatase PTPMT1 is required for hematopoietic stem cell differentiation

21 January 2018

1 reference

An MTCH2 pathway repressing mitochondria metabolism regulates haematopoietic stem cell fate

21 January 2018

1 reference

Regulation of the HIF-1alpha level is essential for hematopoietic stem cells

21 January 2018

1 reference

Abnormal angiogenesis and responses to glucose and oxygen deprivation in mice lacking the protein ARNT.

21 January 2018

1 reference

Placental cell fates are regulated in vivo by HIF-mediated hypoxia responses

21 January 2018

1 reference

O2 regulates stem cells through Wnt/β-catenin signalling.

21 January 2018

1 reference

Cripto regulates hematopoietic stem cells as a hypoxic-niche-related factor through cell surface receptor GRP78.

21 January 2018

1 reference

Meis1 regulates the metabolic phenotype and oxidant defense of hematopoietic stem cells

21 January 2018

1 reference

Stem cell aging. A mitochondrial UPR-mediated metabolic checkpoint regulates hematopoietic stem cell aging

21 January 2018

1 reference

Enhancing Hematopoietic Stem Cell Transplantation Efficacy by Mitigating Oxygen Shock

21 January 2018

1 reference

Lkb1 regulates cell cycle and energy metabolism in haematopoietic stem cells

21 January 2018

1 reference

Mitofusin 2 maintains haematopoietic stem cells with extensive lymphoid potential

21 January 2018

1 reference

A PML–PPAR-δ pathway for fatty acid oxidation regulates hematopoietic stem cell maintenance

21 January 2018

1 reference

Stem cells. Asymmetric apportioning of aged mitochondria between daughter cells is required for stemness

21 January 2018

1 reference

Maintaining tissue homeostasis: dynamic control of somatic stem cell activity

21 January 2018

1 reference

Altered modes of stem cell division drive adaptive intestinal growth

21 January 2018

1 reference

Tissue damage-induced intestinal stem cell division in Drosophila

21 January 2018

1 reference

Invasive and indigenous microbiota impact intestinal stem cell activity through multiple pathways in Drosophila

21 January 2018

1 reference

JNK activity in somatic stem cells causes loss of tissue homeostasis in the aging Drosophila gut.

21 January 2018

1 reference

Lifespan extension by preserving proliferative homeostasis in Drosophila

21 January 2018

1 reference

Intestinal barrier dysfunction links metabolic and inflammatory markers of aging to death in Drosophila.

21 January 2018

1 reference

Modulation of longevity and tissue homeostasis by the Drosophila PGC-1 homolog.

21 January 2018

1 reference

Mutant human embryonic stem cells reveal neurite and synapse formation defects in type 1 myotonic dystrophy.

21 January 2018

1 reference

Increased longevity mediated by yeast NDI1 expression in Drosophila intestinal stem and progenitor cells.

21 January 2018

1 reference

Coordinated changes of mitochondrial biogenesis and antioxidant enzymes during osteogenic differentiation of human mesenchymal stem cells

21 January 2018

1 reference

AMP-activated protein kinase stimulates Warburg-like glycolysis and activation of satellite cells during muscle regeneration

21 January 2018

1 reference

The NAD(+)-dependent SIRT1 deacetylase translates a metabolic switch into regulatory epigenetics in skeletal muscle stem cells

21 January 2018

1 reference

Metabolic control of adult neural stem cell activity by Fasn-dependent lipogenesis

21 January 2018

1 reference

21 January 2018

The genetics of ageing

1 reference

mTOR signaling in growth control and disease

21 January 2018

1 reference

The TSC1-TSC2 complex: a molecular switchboard controlling cell growth

21 January 2018

1 reference

With TOR, less is more: a key role for the conserved nutrient-sensing TOR pathway in aging

21 January 2018

1 reference

Rapamycin slows aging in mice

21 January 2018

1 reference

Metabolic regulation of stem cell behavior and implications for aging

21 January 2018

1 reference

Tuberous sclerosis complex and Myc coordinate the growth and division of Drosophila intestinal stem cells

21 January 2018

1 reference

Notch-mediated suppression of TSC2 expression regulates cell differentiation in the Drosophila intestinal stem cell lineage

21 January 2018

1 reference

TSC1/2 regulates intestinal stem cell maintenance and lineage differentiation through Rheb-TORC1-S6K but independently of nutritional status or Notch regulation

21 January 2018

1 reference

High-fat diet enhances stemness and tumorigenicity of intestinal progenitors

21 January 2018

1 reference

mTOR disruption causes intestinal epithelial cell defects and intestinal atrophy postinjury in mice

21 January 2018

1 reference

Sustained activation of mTOR pathway in embryonic neural stem cells leads to development of tuberous sclerosis complex-associated lesions

21 January 2018

1 reference

mTOR-mediated activation of p70 S6K induces differentiation of pluripotent human embryonic stem cells

21 January 2018

1 reference

Rapamycin and other longevity-promoting compounds enhance the generation of mouse induced pluripotent stem cells.

21 January 2018

1 reference

TSC-mTOR maintains quiescence and function of hematopoietic stem cells by repressing mitochondrial biogenesis and reactive oxygen species

21 January 2018

1 reference

Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells

21 January 2018

1 reference

Constitutively active AKT depletes hematopoietic stem cells and induces leukemia in mice

21 January 2018

1 reference

The Dlk1-Gtl2 Locus Preserves LT-HSC Function by Inhibiting the PI3K-mTOR Pathway to Restrict Mitochondrial Metabolism.

21 January 2018

1 reference

AKT1 and AKT2 maintain hematopoietic stem cell function by regulating reactive oxygen species.

21 January 2018

1 reference

Balancing dormant and self-renewing hematopoietic stem cells

21 January 2018

1 reference

The autophagy protein Atg7 is essential for hematopoietic stem cell maintenance

21 January 2018

1 reference

FOXO3A directs a protective autophagy program in haematopoietic stem cells.

21 January 2018

1 reference

EGF signaling regulates the proliferation of intestinal stem cells in Drosophila

21 January 2018

1 reference

Mitochondrial reactive oxygen species promote epidermal differentiation and hair follicle development

21 January 2018

1 reference

ROS are required for mouse spermatogonial stem cell self-renewal

21 January 2018

1 reference

Proliferative neural stem cells have high endogenous ROS levels that regulate self-renewal and neurogenesis in a PI3K/Akt-dependant manner

21 January 2018

1 reference

Dynamic changes in intracellular ROS levels regulate airway basal stem cell homeostasis through Nrf2-dependent Notch signaling

21 January 2018

1 reference

Resilient and resourceful: genome maintenance strategies in hematopoietic stem cells.

21 January 2018

1 reference

Reactive oxygen species prime Drosophila haematopoietic progenitors for differentiation

21 January 2018

1 reference

Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells

21 January 2018

1 reference

Mitochondrial metabolism in hematopoietic stem cells requires functional FOXO3.

21 January 2018

1 reference

Reactive oxygen species regulate hematopoietic stem cell self-renewal, migration and development, as well as their bone marrow microenvironment

21 January 2018

1 reference

A low level of reactive oxygen species selects for primitive hematopoietic stem cells that may reside in the low-oxygenic niche

21 January 2018

1 reference

FGF-2 expands murine hematopoietic stem and progenitor cells via proliferation of stromal cells, c-Kit activation, and CXCL12 down-regulation.

21 January 2018

1 reference

Monocytes-macrophages that express α-smooth muscle actin preserve primitive hematopoietic cells in the bone marrow.

21 January 2018

1 reference

S1P promotes murine progenitor cell egress and mobilization via S1P1-mediated ROS signaling and SDF-1 release

21 January 2018

1 reference

Connexin-43 prevents hematopoietic stem cell senescence through transfer of reactive oxygen species to bone marrow stromal cells

21 January 2018

1 reference

Direct measurement of local oxygen concentration in the bone marrow of live animals

21 January 2018

1 reference

Distinct bone marrow blood vessels differentially regulate haematopoiesis.

21 January 2018

1 reference

NAD-dependent histone deacetylase, SIRT1, plays essential roles in the maintenance of hematopoietic stem cells

21 January 2018

1 reference

Aging-like phenotype and defective lineage specification in SIRT1-deleted hematopoietic stem and progenitor cells

21 January 2018

1 reference

SIRT3 reverses aging-associated degeneration

21 January 2018

1 reference

FoxO3a regulates hematopoietic homeostasis through a negative feedback pathway in conditions of stress or aging

21 January 2018

1 reference

The MicroRNA-132 and MicroRNA-212 Cluster Regulates Hematopoietic Stem Cell Maintenance and Survival with Age by Buffering FOXO3 Expression

21 January 2018

1 reference

FoxOs are critical mediators of hematopoietic stem cell resistance to physiologic oxidative stress

21 January 2018

1 reference

Foxo3a is essential for maintenance of the hematopoietic stem cell pool.

21 January 2018

1 reference

Roles of Nrf2 in cell proliferation and differentiation

21 January 2018

1 reference

Keap1/Nrf2 signaling regulates oxidative stress tolerance and lifespan in Drosophila

21 January 2018

1 reference

The Free Radical Theory of Aging

21 January 2018

1 reference

Mitochondrial DNA mutations in disease and aging

21 January 2018

1 reference

Premature ageing in mice expressing defective mitochondrial DNA polymerase

21 January 2018

1 reference

Mitochondrial DNA mutations, oxidative stress, and apoptosis in mammalian aging

21 January 2018

1 reference

Erythroid dysplasia, megaloblastic anemia, and impaired lymphopoiesis arising from mitochondrial dysfunction

21 January 2018

1 reference

mtDNA Mutagenesis Disrupts Pluripotent Stem Cell Function by Altering Redox Signaling

21 January 2018

1 reference

Accumulating mitochondrial DNA mutations drive premature hematopoietic aging phenotypes distinct from physiological stem cell aging

21 January 2018

1 reference

Metabolism, longevity and epigenetics

21 January 2018

1 reference

Metabolic regulation of epigenetics

21 January 2018

1 reference

Epigenetics and metabolism.

21 January 2018

1 reference

Transgenerational epigenetic inheritance of longevity in Caenorhabditis elegans

21 January 2018

1 reference

Epigenetic Control of Stem Cell Potential during Homeostasis, Aging, and Disease

21 January 2018

1 reference

Which way does the citric acid cycle turn during hypoxia? The critical role of α-ketoglutarate dehydrogenase complex.

21 January 2018

1 reference

Inhibition of hypoxia-inducible factor (HIF) hydroxylases by citric acid cycle intermediates: possible links between cell metabolism and stabilization of HIF.

21 January 2018

1 reference

Proliferation-dependent alterations of the DNA methylation landscape underlie hematopoietic stem cell aging.

21 January 2018

1 reference

Krebs cycle intermediates regulate DNA and histone methylation: epigenetic impact on the aging process

21 January 2018

1 reference

Aging hematopoietic stem cells decline in function and exhibit epigenetic dysregulation

21 January 2018

1 reference

Epigenomic profiling of young and aged HSCs reveals concerted changes during aging that reinforce self-renewal

21 January 2018

1 reference

Dnmt3a is essential for hematopoietic stem cell differentiation

21 January 2018

1 reference

NAD+ and sirtuins in aging and disease

21 January 2018

1 reference

21 January 2018

1 reference

Cdc42 activity regulates hematopoietic stem cell aging and rejuvenation

21 January 2018

1 reference

Oxidized low-density lipoprotein induces hematopoietic stem cell senescence

21 January 2018

1 reference

Hypercholesterolemia induces oxidant stress that accelerates the ageing of hematopoietic stem cells

21 January 2018

1 reference

Prolonged fasting reduces IGF-1/PKA to promote hematopoietic-stem-cell-based regeneration and reverse immunosuppression.

21 January 2018

1 reference

Global analysis of proliferation and cell cycle gene expression in the regulation of hematopoietic stem and progenitor cell fates

21 January 2018

1 reference

Dietary restriction improves repopulation but impairs lymphoid differentiation capacity of hematopoietic stem cells in early aging

21 January 2018

1 reference

Mitochondrial metabolic reprogramming induced by calorie restriction.

21 January 2018

1 reference

Calorie restriction induces mitochondrial biogenesis and bioenergetic efficiency

21 January 2018

1 reference

Short-term calorie restriction enhances skeletal muscle stem cell function

21 January 2018

1 reference

Taking a "good" look at free radicals in the aging process

21 January 2018

1 reference

JmjC enzyme KDM2A is a regulator of rRNA transcription in response to starvation.

21 January 2018

1 reference

Suppression of oxidative stress by β-hydroxybutyrate, an endogenous histone deacetylase inhibitor

21 January 2018

1 reference

Metabolic pathways promoting cancer cell survival and growth

21 January 2018

1 reference

Serine, glycine and one-carbon units: cancer metabolism in full circle

21 January 2018

1 reference

In vivo cellular imaging pinpoints the role of reactive oxygen species in the early steps of adult hematopoietic reconstitution

21 January 2018

1 reference

mTORC1 controls the adaptive transition of quiescent stem cells from G0 to G(Alert)

21 January 2018

1 reference

12 December 2020

Rapamycin fed late in life extends lifespan in genetically heterogeneous mice

1 reference

12 December 2020

Changes in mitochondrial reactive oxygen species synthesis during differentiation of skeletal muscle cells

1 reference

12 December 2020

mTORC1 in the Paneth cell niche couples intestinal stem-cell function to calorie intake.

1 reference

12 December 2020

Mitochondrial fusion directs cardiomyocyte differentiation via calcineurin and Notch signaling

1 reference

12 December 2020

Hematopoietic senescence is postponed and hematopoietic stem cell function is enhanced by dietary restriction

1 reference

12 December 2020

Somatic Progenitor Cell Vulnerability to Mitochondrial DNA Mutagenesis Underlies Progeroid Phenotypes in Polg Mutator Mice

1 reference

12 December 2020

Redox regulation by Keap1 and Nrf2 controls intestinal stem cell proliferation in Drosophila

1 reference

12 December 2020

Stem cells: units of development, units of regeneration, and units in evolution

1 reference

12 December 2020